PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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 Type: Rx Drug

  

PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  ovaries removed F 44 2 years
2/9/2005
 3  
2/7/2005
 5  hysterectomy with one ovary left 10yrs. after surgery started getting hot flashes/insomnia & went on .3MG for 6 years then got off. After 2yrs off, hot flashes/insomnia came back with a vengence, day & night! I am back on .3MG and don't care if I ever get off. The risk is worth it to me. My legs ached to no end when I went off it, headaches were unbearable, usually 28 days out of a month, many of those days were spent in bed. F 51 6.5 years
1/30/2005
 5  Hysterectomy with ovaries out I have been taking premarin since 1986 when I had my surgery. I have felt wonderful and expected to take it the rest of my life. Now my doctor says I should go off. I have been off for three months and my hair is thinning. My hair was thick and full while on the premarin. I thought it was good for the skin and hair. I am so disscouraged I am thinking of going back on. Anyone with this problem? Great drug! My quality of life was maintained at 32 and I never felt better! F 56 19 days
1/22/2005
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 5  Surgical Menopause both ovaries None - Premarin has been a life saver. I don't care if it's from horses urine...most people EAT animal don't they...so I don't understand what the big deal is there. Recent studies scare me a little bit...but wait and new studies will reveal something different. The benefits I get while on Premarin far outweigh the risks! I will stay on it as long as I can just for current quality of life if nothing else! F 39 5 days
1/4/2005
 4  total hysterectomy Since starting on Premarin 5 years ago I've gained weight, I have joint pains and get so stiff its like I'm 95 instead of 35.I have done all the things I did before Premarin to lose weight only to get on the scales and find I've actually ADDED pounds. I have decided to stop taking it and see what happens. F 35 5 years
12/26/2004
 3  Hot flushes 12/10/04 - I have been on Premarin for 8 years and 3 years ago I stopped it immediately. The doctor said I could go off it but she didn't tell me to wean off it. Don't ever just stop!!! I went into such a terrible depression, rage and couldn't sleep well. The pharmasist told me it was because I went off it cold turkey. I went right back on in a high dose, and have been weaning off it. I am now down to one a week and the symptoms are coming back so I'm going to increase the dose to every 3 days and am staying on it unless someone can come up with a better idea. I WISH I'D NEVER STARTED IT! F 58 9 years
12/10/2004
 1  SURGERY EXPERIENCED MOST OF THE SIDE EFFECTS LISTED, ALSO MENTAL SIDE EFFECTS NOT LISTED...IT BECAME A NIGHTMARE. DO NOT TAKE!!!FOR ANY REASON FOR ANY LENTH OF TIME...ALSO READ HOW IT IS AQUIRED...IF YOU FEEL YOU NEED ESTROGEN...THE NATURAL OR HERBAL WORK, AND DO LESS HARM, THERE IS MANY NATURAL HEALTH HELPS AVAILABLE. F 63
10/12/2004
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 3  full hsyterectomy including ovaries Premarin did help with hot flashes and mood swings, but my blood pressure was becoming high. Since I have been off of Premarin since May 2004, I now have hot flashes. I am now current taking Lexapro for my mood swings and I am living with the hot flashes and chills. I believe I will have these hot flashes/chills for at least two years, but at least the blood pressure has been lowered. F 44 19 months
9/26/2004
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 5  Hysterectomy with 1 ovary removal Breast tenderness for a couple of months. I started taking it because I was not feeling well. Fuzzy mind, emotional, hot flashes, losing my hair, depressed. Heart palpitations, anxiety. Premarin has helped me and I feel great. I am very concerned about Cancer, either breast or ovarian. But I am not ready to go off of it. F 46 3 years
9/22/2004
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 4  perimenopausal symptoms weight gain I began taking Premarin for night and day sweats, the feeling that F 47 1 years
9/13/2004
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 1  hot flashes No immediate side effects except a little weight gain, which I was happy with because I was thin at the time. A few years after I was on premarin (and I tried all the various combinations) I still had the hot flashes but added heart palipations. Then just gradually I developed migraines which got worse every year. After trying everything, and quit the premarin. Headaches have lessened over the years. Also heart palipations are gone. If you are experiencing migraines or heart palipations and you are taking premarin it could be the cause. Because of the heart paliptations I was diagnosed with prolapse valve and put on Inderal for a couple years. Then when trying to get off Inderal gradually, I almost had a heart attack, so was put on a different med to gradually get off Inderal. I can't say that premarin really did me any good for over 20 years, but I was brainwashed into believing, if we did not take premarin we would get old and our bones would break. F 65 20 years
9/11/2004
 2  after hysteroectomy gained 40 lbs, blood sugar shot up, blood pressure went up, cholosteral went up. The weight gain has been the worst part of the experience. I was put on actos for diabetes along with the premarin after my hysteroectomy. I just kept gaining weight and had no energy. I am now off premarin but the damage has been done. F 60 7 years
9/9/2004
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 4  hysterectomy 25 lbs weight gain. Not able to lose the weight, have been trying for 7 years. I even joined a gym. Any tips on how to lose the weight? Legs aching all the time. The pill really helped w/ hot flashes & night sweats. F 46 7 years
9/5/2004
 4  hysterectomy weight gain can't seem to loose the weight . that alone will make a women depressed. is there any way to not gain weight ? when on this drug I mean it helps but then you are a emotional wreck. F 45 18 years
8/30/2004
 2  surgical hysterectomy WEIGHT GAIN! I went down to the lowest dosage possible, and I still couldn't get the weight off. I quit Premarin after two years and feel fine. Three weeks, a diet and some exercise, and I'm down twelve pounds. Take lots of soy to battle the hot flashes. I take soy and calcium faithfully twice a day, and I'm fine. F 45 2 years
6/26/2004
 4  hysterectomy No side effects during the 24 yrs I took Premarin. Felt great. Due to recent studies, my doctor urged me to stop Premarin. I have been off Premarin for only one month. I am now suffering from severe leg stiffness. Also experience stiffness after sitting for short periods. Now my fingers are being affected with stiffness after a nights rest. My quality of life has been greatly affected. F 66 24 years
6/17/2004
 4  Hysterectomy + ovary removal Thought I was gaining weight. Just a shift in what I have. Went off premarin for 3 weeks. Headaches, depression, couldn't sleep more than 1 1/2 hours at a time. Hot flashes, night sweats. After 3 weeks I gained more weight, so I started taking premarin again. The weight is gone. Also started trying to be more active and that helps a lot. Had water retention, but once I started an excercise program it's not as bad. Don't think I'll try getting off again. F 47 4 months
6/8/2004
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 3  Total Hysterectomy Very itchy rash on lower legs and stomach Weight gain, hair loss 1.25 mg doseage, previously .62mg Tested recently and increased to 1.25, hot flashes, depression, spotting disappeared on increased dosage. F 47 32 months
5/19/2004
 1  To treat vaginismus from episiotomy Continued pain in perineum Not worth it. Terrible drug. Derived in a cruel manner by forcing female horses to remain pregnant while dehydrating them to collect concentrated urine (and their babies are destroyed). Horrible medicine--should never be on the market! F 31 2 weeks
5/4/2004

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