PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Total hysterectomy at age 25 same as with regular menstrual cycle - increased water retention during course of the month and some tenderness in breasts with a decrease of side effects during last 5 days of month when not taking the medication At age 50 my doctor advised that I stop taking Premarin because of the possibility of susceptibility to heart attack, cancer and stroke. As a direct result began having hot flashes, night sweats, dry skin, reduced mental acuity, was unable to sleep, had loss of libido, acute joint pain and depression. I suffered miserably with these problems for 8 months and they did not diminish. After taking into consideration my reduced quality of life, I decided that it was worth the risk to begin taking Premarin again to see if the probems would disappear. I began taking a dosage of 1.25mg every other day and was relieved to find that my symptoms began to disappear within a week or so. I am currently taking .625mg/day and have some joint aches and pains, drier than normal skin, occasional mood swings, weight gain and fluid retention. Overall I think the possible risk of stroke, cancer and heart attack does not outweigh the poor dally quality of life that I experienced while not taking Premarin. Possibly I may live a few years less, but my quality of daily life is far superior when taking the drug; therefore I will continue to take Premarin. After having read some of the comments here, I considering taking a higher dose to see if the joint aches and pains occasional night sweats, loss of libido and dry skin and mood swings disappear altogether. F 63 38 years
.625 1X day
10/31/2011
 5  Total hysterectomy at 35 years old. I have had no side effects whatsoever. I am now 75 years old. I can outdo my children. I have no arthritis. My skin looks very good for my age. I have a nice head of hair. My friends thinks I look much younger. My doctor has wanted me to get off the Estrogen many times through the years but I have refused to do so, at one time having to change doctors. If someone has a stroke or heart attack, just because they are taking estrogen, they blame it on the drug. Many people have strokes and heart attacks that have never taken estrogen. I told my doctor that I am not willing to go through a lifetime of suffering just because I may or may not one day have something happen to me, that may or may not be the effects of the drug. There are side effects from any drug on the market. F 75 35 years
1.25 1X day
10/11/2011
 4  total hysterc. none yet I am only 28 but had to have everything taken out. I still have hot flashes some times but they have decreased the longer I am on premarin. I think I am on the highest dosage. My doctor also said I could take half in the morning and half at night to help with any side effects...not sure if this will help anyone else but it has helped me F 28 2 months
1.25 1X day
9/23/2011
 5  TOTAL HYSTERECTOMY NO NEGATIVE SIDE EFFECTS DEXISCAN PERFEECT/SLEEP WELL/.FEEL HEALTHY/ NEW GYN ASKED ME TO SWITCH TO ELESTRIN LAST WEEK/ CANNOT SLEEP/ NIGHT SWEATS/HAVE GREAT SKIN/ALERT AND VERY HAPPY WITH PREMARIN /NOW I HAVE TO PERSUADE GYN TO WRITE Rx FOR PREMARIN. F 85 41 years
0.625 1X day
9/7/2011
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 5  Complete hysterectomy Weight Gain Recently I was taken off premarin for an upcoming MRI - I have had night sweats, weight gain, fatigue, depression, trouble sleeping, hair loss, dry skin....I CAN'T wait to get back on it. It is the bomb for me. My mother has been on it for 35 years and has not suffered any bad side effects. It has been a huge help to me. I had a Complete hysterectomy at 45. I am thankful for the drug. For those of you that do not react well with it, there are natural remedies that work well too. F 51 6 years
.925 1X day
8/18/2011
 5  Total hysterectomy at age of 28. No side effects I feel terrible when I am off of Premarin. I have joint aches, headaches, hot flashes etc. when I miss a dose. My doctor said to wein myself off by taking one every 2 days. I have noticed joint pain everywhere and my skin is drier. I have been depressed. I am going back to my regular dose. I have never had high blood pressure like many of the comments I have read. My doctor told me that he has had 3 women in their 70's that have been on Premarin for over 20 years that have wanted to get off of the drug. They called him back a week later and told him to never let them do that again. I will be on this drug until God calls me. I can't stand to feel bad. I am 56 years old and feel very young. Great skin, great sex life. I just need to start my work out plan again and lose weight and I will fell like a million bucks. I am so glad I found this website and read all your comments, because it has helped me with the decision to never get off Premarin. F 56 28 years
.625 1X day
8/17/2011
 4  Removal of ovaries when I was 32 I did not notice any side effects-now at 67 my doctor lowered my dosage amount to 0.625MG. After reading all of the reports-I have stopped using premarin 2 months ago. My entire body aches,I do not sleep well and I have night sweats.I have Vagifem. However, I do not want to start another drug that may increase my risk for heart problems or cancer. While taking premarin my desire to have sex good. I have been on the premarin for over 15 years and not sure how I will feel in 6 months. F 67 15 years
0.9 1X day
8/1/2011
 5  total hysterectomy before premarin lack of sleep,mood swing,HOT FLASHES,LEG PAIN.WEAKNESS.after premain the first two weeks WOW feel like a new women.but after about two months hot flashes can back went to see my ob dr and he incre my premarin to 0.9 WOW again feel great now my only concern is the weight gain and bloating. tried to stop cold because of the weight gain made me a little depressed.so off for about two weeks and i am haveing mood swing., crying spells.body pain,hot flashes.so the bottom line i love how premarin makes me feel so i have join the ymca and started to take aqua water fitness. if i get real with my self and not blame it all on the premarin i can do better with my eating. so yes i will stay on the premarin and try to do my part will keep you all update. pray for me and i will pray for you. F 43 8 months
0.9 1X day
7/19/2011
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 2  extreme hot flashes only started the medication 1 week ago but I feel horrible. I have been very depressed, nauseated and i ache all over. If i didnt know better I would think i had the flu. Also having stomach pain. I dont know if symptoms are from the medication. I will try for a little longer. If symptoms dont improve I will contact the dr. F 52 1 weeks
.625 1X day
6/12/2011
 4  Vaginal atrophy,dry skin,osteoporosis Mood Swings, Bloating, hot flashes, back pain and headaches My doctor put me on Prempro 0.625 once/day and Premarin vaginal cream once daily at bedtime, my husband and I had pretty much stopped having sexual intercourse due to the severe pain it was causing me, no lubrication we tried helped and for 2 yrs. that was what we were dealing with, then a friend told me about the Premarin vaginal creme and I saw a Dr. at a local clinic and she got me started on both medicines last week. In less than a week my husband and I was able too resume having sexual intercourse with no pain whatsoever. Then the next day I started having bad mood swings and hot flashes, my head and back hurt all the time and I had bloating so bad I looked pregnant. I didn't want to discontinue taking it so I decreased it to half a tablet and stopped using the cream altogether and I'm doing so much better on the half tablet. The odd thing is I never really had any hot flashes and mood swings before I started taking the Prempro or Premarin. If I can do it without the severe side effects, I plan on sticking with it for now. I don't think this is something I'd want to do without taking a break every so often. F 53 9 days
0.625 mg. 1X day
6/11/2011
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 5  hysterectomy and ovaries removed none I was put on this immediatly after ovaries removed. Dose of 1.25mg. and now was decreased to .625mg. per day. I did have some migraines but they were associated with stress! I have tried to lower dose but skin has gotten very dry,palpitations, anxiety and mood swings with depression was bad.Also started growing facial hair and had to shave daily! It lowers my blood pressure and helps me. It does help with cholesterol levels. My GYN said to increase it to .9mg/day and I will. Some fluid retention until body regulates to it but it is worth it. I also have a history of heart attacks but that was before the premarin and it has caused no cardiac problems in 26 years. I will take it as long as I can. F 51 26 years
.625 1X day
6/7/2011
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 5  complete hysterectomy none Over the last 10 years I have reduced my dosage from 1.25mg to .625mg daily. My Doctor wants me off completely because heart disease is prevalent in my family. We continue to debate this. I continue to take .625 mg. At age 48 my previous physician told me his 94 year old Mother was still taking Premarin and I should too. 59 37 years
1.25 1X day
6/2/2011
Email
 5  Early Menopause at Age 30 I did not experience any side-effects. I actually felt pretty good while taking Premarin. My skin still looks good and people tell me I look younger then my 55 years. But that being said, I think it's time to give my body a break. I also take Provera from the 1st of the month to the 12th, then usually on the 15th I have a period. Frankly, I am tired of the whole period thing at my age and this last one was a doozie! I called my GYN yesterday and discussed this with her and she said to just stop taking the Premarin and see how I felt. It's only the 2nd day that I have not taken one so don't see any real changes, YET. Guess I am waiting for the other shoe to drop, so to speak. Anyone else quit cold turkey? If so, and you have developed menopausal symptoms while off the Premarin, how long do the last and can you work through them? Thanks! F 55 25 years
0.625mg 1X day
5/19/2011
Email
 3  menopause I just had a complete physical and it was found my hormones were totally whacked out and the doctor was surprised I'd had any energy or hair left because of the drastic hormone imbalance. I have been tired but I do work 3 jobs - and absolutely no trouble sleeping. I think I've had maybe half a dozen hot flashes in the past year, and days where nothing makes sense. My doctor suggested two hormone pills to take daily and supposed to go back for blood work again in two months to see how the treatment is doing. I've never taken any prescriptions other than an antibiotic for sinus infection about ten years ago. I don't even take tylenol. In reading these comments, I'm now fearful of premarin .3mg. Other than hormone imbalance, there is nothing wrong with me. F 51 2 days
.3 mg 1X day
5/3/2011
Email
 5  Extreme hot flashes after No side effects all these years I had a stroke last Friday and the Doctors did not find any cause why I had it w/every test they could give me but told me to immediately stop taking premarin. Now I can not sleep at nite and memory has slowed down and very nervous. I will be calling my GYN Doctor for an appointment to discuss this-my body feels terrible and I had no trouble over these years at all. Of course we are all different but had been very happy over all these years w/no complications. F 67 28 years
1;25 1X day
3/18/2011
 5  complete hysterectomy- 30 yrs old None. Now, after the reports of cancer and stopping taking it, I'm having hot flashes. How long do they last??? Never had any side affects, just didn't have to suffer the hot flashes. If there isn't any hope of getting rid of them, I'd go back to taking it again. F 77 47 years
.625 1X day
3/6/2011
 2  Hot Flashes and night sweats Headaches, weakness in my legs, lower back pain, depression, upper respirtory infections, continous coughing, weight gain and lack of sleep. I'm wanting to quit cold turkey, I hope this doesn't cause me any problems? I'll try to handle this menopause with nothing at all, instead of killing myself with this drug. F 50 2 years
1.25 1X day
3/3/2011
Email
 1  Total Hysterectomy Never experienced any side effects until. . . Feb. 26, 2011 I had a "mini-stroke" or TIA. I was given every test imaginable and everything came back normal. The only link seems to be the Premarin. Quit cold turkey. No other choice. F 44 4 years
.9 1X day
3/1/2011
 5  after hysterectomy bad time only good ones beleive it or not I stayed on Premarin for 27 years doc said it was ok then a lady doctor came to my surgery and said to come off them.she gave a half dose and then finished. At 77 I am having all menopausal symptons and feel like a wet rag and in general pretty lousy.Dr gave pills to combat this but they do no good F 77
1..25 1X day
2/20/2011
 1  menopause It is the WORST KIND OF ESTROGEN TO TAKE!!!!! BEWARE...IT GAVE ME BREAST CANCER..I JUST FOUND OUT 2 WEEKS AGO. I AM SICK ABOUT IT...I FEEL LIKE I GAVE IT TO MYSELF...TAKING IT KNOWING THAT IT "COULD " CAUSE BREAST CANCER...I THOUGHT I WOULD TAKE IT FOR A SHORT TIME AND I WOULD BE OK. I AM NOT OK. I KNOW OF ANOTHER FRIEND WHO GOT UTERINE CANCER FROM PREMARIN. DO NOT TAKE IT. WHY DID I TAKE IT YOU ASK? BECAUSE I TRIED APPROX 4 OTHER KINDS OF ESTROGEN AND ESTROGEN/PROGESTIN COMBOS AND THEY EITHER MADE ME CRANKY, WAY TIRED, OR DID NOT WORK FOR HOT FLASHES. I HAD DEBILITATING HOT FLASHES TO THE POINT OF IT MAKING ME SICK. SO I TRIED PREMARIN...ALTHOUGH IT WORKED BETTER THAN ANYTHING ELSE I HAD TRIED FOR HOTFLASHES...I STILL FELT CRANKY....BUT SINCE IT WAS BETTER THAN ANY OF THE OTHERS...I TOOK IT FOR 3 YEARS. I NOW HAVE BREAT CANCER..DON'T TAKE IT, TRY SOMETHING ELSE...!!! THERE ARE NOW OTHER THINGS TO TRY OUT THERE, THAN THERE WAS WHEN I HAD MY HYTERECTOMY 14 YEARS AGO. IT SHOULD BE TAKEN OFF THE MARKET YESTERDAY.!!!!!!!!!!! F 49 3 years
.09 1X day
2/4/2011

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