PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  mild hot flashes and much anxiety I actually believe Premarin cured my headaches. I had migraines before and they quit after I started taking it. I'm now on the lowest dose. If I miss a few days, though, I get pretty clammy. Otherwise, I feel great. F 58 7 years
6/5/2006
 3  Complete Hysterectomy Weight gain, especially around the mid section. It's horrible, I have been going to the gym and trying to eat sensibly, and I can't get into a size 16; I'm only 4'9", always been on the heavy side, but this is ridiculous and brings me to tears. Also, the vaginal dryness and soreness with intercourse is not good. Libido seems to be low. (In a new relationship, this is not good) I have noticed blurred vision, but thought it was because of my age, but maybe not. I have also noticed I cry more and am more sensitive. F 45 2 months
5/8/2006
 5  Total hysterectomy The biggest at first was weight gain. But when I stopped and/or cut on the Premarin after years of taking it memory loss, headaches, mood swings, bed sweats, high blood pressure, and nervousness occurred. 1.25mg was the best dosage. 3 years ago, because of the controversy with Premarin I decided to stop taking it. The side effects kicked in. I had no idea what was wrong. After visiting my doctor, he put me back on Premarin and weeded me off instead. He cut me to .3 mg but it didn't help and switched me to .625 mg. I’ve been on it for 6 months. The bed sweats and headaches are back. I also developed mood swings, memory loss and nervousness. I’m not getting sleep at night and my energy level is low. I’m a 55 years old. I don't smoke, drink socially and has always been in great physical shape. I’ve gain 20 pounds over the past 5 years. I’ve always been a slender lady as it runs in my family. My doctor strongly advised I lose at least 10 pounds as he sees me approaching boarder line diabetes and the weight loss will prevent hitting the “concern zone.” I've scheduled an appointment with my doctor. Hopefully, he can get me back on track. F 55 12 years
4/23/2006
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 4  hyst, 1 ovary stopped functioning breast fullness only I had a hysterectomy at age 34 for cervical cancer. They left 1 ovary which stopped functioning after 5 yrs. I began experiencing sleeping problems, vaginal dryness and mild depression. The Dr. ran testing to see if the ovary that remained was still functioning. The tests showed I was actually post-menopausal. My Dr. prescribed Premarin which completely resolved all symptoms. After all the publicity of prempro I asked the Dr. about premarin. He said there is little worry in women who have had hysterectomies. He also stated that he only keeps women on premarin until they are at normal menopausal age. He felt this was around age 51-55. Of course this age in nature varies. He explained that it should be used as a supplement to provide extra estrogen during the time you would naturally be producing higher levels of estrogen. I asked about the progesterone. He said if you didn't have a uterus it is not necessary nor helpful. When you talk about long term effects. Premarin has been around fo F 46 7 years
3/24/2006
 5  Hot Flashes - partial hysterectomy Weight gain - may not be from Premarin. Quit smoking around the same time found out my thyroid wasn't working. I had a partial hysterectomy in 1996 and started having the hot flashes roughly four years ago. Had been taking Estroven for that time but the hot flashes were disrupting my life. Started seeing an improvement within weeks. I believe this stuff saved my life. I was concerned about the Breast Cancer scare but my doctor says it's when you mix the estrogen and the other one together is when the risk comes in. Having yearly mammygrams will also decrease your risk of breast cancer deaths. Thank you Premarin - you saved my life. F 47 8 months
3/23/2006
 2  Total Hysterectomy Horrible migraine headaches........pounding in head. 3 trips to emergency room. Kept me the third time and did tests. MRI. Found nothing. Think that it is the Premarin. I see the Doctor Monday........It has been BAD,,,I was fin for 3 weeks after the hysterectomy and then BAM....It hit me hard. I thought I was having a heart attach or a stroke. I hope that this dosen't happen to anyone else. F 47 4 weeks
2/19/2006
 2  Total hysterectomy (11-05) Started Premarin immediately after surgery (11-26-05). Sometime in December '05-January '06, started with ringing in my ears, then headaches in the back of my head. Over the past weekend, SEVERE headache that pulsed, pounding heartbeat, and BP of 160/100(!!) My usual BP runs in the area of 120/72. Thought I was goin g to either have a stroke or a heart attack. Went to my MD who said it MAY be the Premarin. I went off of it 3 days ago. Still have ringing in my ears, but the headache is better and BP is down, in the evening to normal.I will most likely stay off this medication if I continue to improve with the headaches and BP. I feel that I would have had a major cardiac event if I continue with it. F 51 3 months
2/15/2006
 5  Total hysterectomy at age 28 I have never had any real side effects .... I believe it even helps me mentally ... I do have swollen ankles sometimes...but that could be due to many things... I did not like the weight gain ... I assume came from the premarin because it effects your thyroid .. I have never had a problem related to premarin ... except the prempro...which effected my eyesight..lucky I figured it out quickly...and my eyesight returned to normal... which I was told would not happen...I feel no one should take the prempro.. .. I've taken regular premarin 1.25 since 1971 ... and feel it keeps me young ... many people compliment me on my youthful appearance ... could be genes ... but it is a fact you have more hormones when younger and better skin.... F 65 35 years
2/4/2006
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 5  totaly hysterectomy None I did not mention in my orginal entry.....My surgeons recommended I take the premarin 3 weeks and leave off one week and I have always done this...which is more in tune with your body as before...I have had doctors argue with me...but I maintain the the time elements are important and the surgeons correct...I have done much research on hormones and their cycles... It is not normal to the body to have the same amount of estrogen all the time...progesterone cream is used the last week...just as the body would cycle these hormones... F 65 35 years
2/4/2006
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 5  Complete Hysterectomy I wrote a post here about 6 months ago (read below)...well my sister has since passed away from Breast Cancer...which was feeding off estrogen. When I last wrote the post I was determined to stay on Premarin...but my doctor told me to get off it asap...because of my sister. I HAVE BEEN OFF PREMARIN FOR 3 MONTHS...AND OTHER THAN THE OCCASSIONAL HOT FLASH - I FEEL MORE WONDERFUL THAN I EVER THOUGHT I WOULD. I CAN'T EVEN BELIEVE IT! EXCERCISE ALSO HELPS WITH THE HOT FLASHES IN THAT I DON'T GET THAT MANY. JUST TAKING CALCIUM FOR MY BONES...BUT I FEEL AWESOME...DON'T BE AFRAID IF YOU HAVE TO COME OFF OF IT...KEEP A POSITIVE MIND! KEEPING MIND OVER MATTER REALLY HELPS YOU TO OVERCOME MANY OBSTACLES!! F 40 5 days
1/25/2006
 1  external/internal vaginal dryness bloating, unusual bleeding with menstual cycle, more dryness and pain Just getting word out that I've read some articles about how premarin is made from HORSE URINE. These horses are treated extremely inhumanely also. My gag reflexes kicked in when I read one article. Also, premarin causes cancer and it's made with mineral oil which is a cheap substitute for real lubrication products. Mineral oil actually dries you out more. I'm definitely writing my doctor and letting her know what I've found. F 28 5 days
1/24/2006
 1  external/internal vaginal dryness bloating, unusual bleeding with menstual cycle, more dryness and pain Just getting word out that I've read some articles about how premarin is made from HORSE URINE. These horses are treated extremely inhumanely also. My gag refelxes kicked in when I read one article. Also, premarin causes cancer and it's made with mineral oil which is a cheap substitute for real lubrication products. Mineral oil actually dries you out more. I'm definitely writing my doctor and letting her know what I've found. F 28 5 days
1/24/2006
 5  Total hysterecomy at age 35 None that I can discern, except those arising from the removal of ovaries and uterus, such as vaginal dryness, etc. Primarily due to my proactive concern about future risk of Alzheimer's Disease, I intend to take Premarin forever. I feel great, look 20 years younger than chronological age, & have never had a hot flash since Premarin was literally administered on the operating table & I've never been without it since 1981! F 60 25 years
1/11/2006
 5  Hysterectomy ovaries removed@age23 Premarin has been a life saver for me. Has helped with night sweats, mood swings. Although over the years I have been weening myself to a lower dosage. I haven't had any problems with taking it. I am currently taking .625 every two days. F 48 24 years
1/8/2006
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 1  menopause just pain in legs and feet had breast cancer had to have masectomy. if you think the hot flashes are bad wait till you have chemo and get those hot flashes and cold chills so bad you shake all over. no one told me it could cause cancer. F 55 16 years
1/6/2006
 1  surgical menopause Felt tired, had foggy brain, low energy, no sex drive, migraines daily 14-16 hours after taking each dose. Switched to an estrogen patch, and am back to being myself! M 33 2 weeks
1/5/2006
 5  HOT FLASHES, NIGHT SWEATS Since 1987 gained 60 pounds, hard to lose, No more sweating, occasional slightly blurred vision, hair loss (had too much to begin with anyway) stopping suddenly caused rage and sweating all night. Just not worth it. Stopping gradually caused vaginal dryness and the hot flashes started up again. F 61 22 years
11/17/2005
 5  Hot flashes at 42,total hysto at 47 My eye sight deteriorated, but that is always to be expected after age 40. Last few years heart rate went up and blood presure and cholesterol, but I believe that is a side effect of the Effexor I am on. I felt SO much better once I was placed on Premarin. I welcomed some weight gain, but once I was at desired weight, I am able to control my weight with Calory counting (same as weight watchers point system). 2 Years ago I started to get break through hot flashes, not really bad, but mentioned it to the Doc. He gave me 3 different types of HRT to try, and adviced me to look for homeopathic herbs in addition (black Cohosh, Soy, estrovan, etc... ALL) The 3 different types of other HRT did not help. I weaned off all HRT and stuck it out with herbs for ONE WHOLE YEAR. I ended up almost insane (Head in freezer)and in addition I was hopitalized with a Phsychogenic stroke (4 months with no HRT), convulsions, mental hospital stay ( at 9 months after I stopped with HRT's). On disability and all ($710 a month). NO quality of life. My MD would not prescibe premarin again for me (he thinks I am nuts by now) I asked my Psych Doc. to be placed back on Premarin 1.25mg/day April this year, which he d F 52 10 years
11/16/2005
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 5  Hotflashes 42/total hysto 47 I have noticed the blurred vision, also more in one eye then another. Sugar has gone up, and now also Hormones from the adrenal gland dont seem to work properly ( Urge to Urine, frequent unrination, Large amounts of urine and discomfort with urination.(tested twice negative for UTI). I urinate 30% more then that I drink. Hands and ankles a little swollen of and on since about the last 6 months. BUT........(This can NOT be related to the Premarin) I am looking into disorders of the Pituitary gland, which controls most of ALL hormones in the body. Disorders from the pituitary gland seem to have the same signs and symptoms as the side effects of the Premarin. I think I will check with an endocrinoogist. F 52 10 years
11/16/2005
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 4  Complete Hysterectomy Dry eyes. I went off premrin for 3 months I was trying Bio-identcal hormones Changed doses 3 times still could not sleep at night. skin was tired looking and my body seemed to be flabby I went back on Premrin .0625 feeling no anziety and sleeping. I know I will stay on as long as I can. I figure by 50yr. old I will try again. that will be 10 more years. No real side effects I actually gained weight off the Premrin. F 40 17 weeks
11/1/2005

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