PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Night sweats, restlessness, hypertension None Started with .6 but didn't work and changed Dr who gave me 1.25. My hypertension disappeared and the sweating F 46 2 years
1.25
12/29/2018
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 5  Partial Hyst.& premen.hot flashes none that I noticed I get extremely hot at times when others are not. Thought it might be time to get off Premarin. After reducing amount over 5 months, am still hot and now am having hot flashes on top of it. Thyroid med. just lowered, may help, but I may have to go back on the Premarin. This drug should be considered habit forming. F 72 20 years
.625 1X day
10/29/2018
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 1  Menopausal symptoms After taking Premarin for 6 weeks my body looked as thought it had been inflated with half set jelly. It took a further 6 weeks to find out the weight gain had been caused by the Premarin. I stopped taking at the end of July 2017 and so far despite rigid dieting and exercising at the gym 3 times a week I still cannot shift the weight gain caused by the medication. I had spent the previous 3 years losing over 7 stones in weight and had an operation to remove the loose skin. I had the body I had worked so hard for, then I was given Premarin and it has all been destroyed. I am devastated and depressed with no help from Pfizer or my GP Don't take it, it will destroy your life F 65 12 weeks
0.625
10/2/2018
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 5  Total Hysterectomy at 32 After my total Hysterectomy at 32 I was placed on premarin and had no side effects at all .and have stayed at .625mg a day A couple months ago ,something started to change .. I Have these severe hot flashes ,I'm losing my hair in patches ,I'm having trouble sleeping ,very anxious,forgetful ,and depression.and irritability. since I have been fine on .625 all these years it never occurred to me until tonight I am feeling all the effects of menopause! Until this happened I was going to start weening myself off ,but now I am going to increase the dosage ! It's been exhausting and miserable ,I hope it makes me feel like I always had 💗 F 46 14 years
.625
9/22/2018
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 5  Complete hysterectomy No effects I want to know if its causing cancer F 51 7 years
4/11/2018
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 5  complete hysterectomy none I beleive as soon as I got on them they began to work their magic and continued throughout the years. Lucky Me. Back in the day I remember when I was younger the older ladies use to call them the banana pills. Do not ask me why, maybe because mine are oblong and yellow, yet not all premarin are looking the same. Yes I have additional comments. I was suggested by physicians a few times to get off of premarin and I tried until I experienced physical pain that I didn't like and at the time I was on percocets and that didn't kill the pain. So as I continued to suffer I said enough is enough. As i went back on my Premarin the pain went away just like that, therefore I told the Dr at the time. Then once again to the next Dr and then again to the next Dr then after this many times I said enough is enough because everytime it was the same, Pain. A new Pain. Comming from not being on Premarin so Drs said my body is addicted or my body needs it and I say I don't care just give me my script I need my Drug!!!!!!!!!!!! F 67 37 years
1.25mg 1X day
1/14/2018
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 5  Total hysterectomy My history: I had hormone NEGATIVE/Her2 Positive Breast Cancer 5 1/2 years ago. During chemotherapy, my constipation was so horrific it caused a cystocele and rectocele. Nine months after I completed chemotherapy, I decided to have it repaired. My GYN told me I should just get a total hysterectomy “while she’s in there” because “you never know.” My genetic testing was negative and my oncologist was not concerned about ovary removal because I was hormone negative. I have regretted that decision (to remove my ovaries) daily. I once had beautiful, thick hair and nice skin. Now it is thin on top and my skin looks old and pale. My hot flashes are HORRIFIC. My quality of life HORRIBLE. I was angry, hateful and depressed. I tried Effexor, Clonidine, and multiple other medications without success. Once more research was published about my type of breast cancer, I learned that estrogen actually blocks the androgen that fueled my breast cancer. So, I was given clearance to try estradiol. I started with the oral route, switched to the patch, then to bioidentical hormones, always resulting in massive post-nasal drip, nausea, headaches, weight gain, swelling, etc. So, I suffered. I recently found this site and learned that some women tolerate Premarin much better than estradiol. So, my GYN prescribed it (with my oncologist’s approval) and although it’s only been a few days, I am thrilled to say, I have had minimal side effects (whereas with estradiol My quality of life was horrible and I suffered. I could have gotten past my appearance had I not endured crippling hot flashes and heat intolerance (I live in the South and can rarely go out in the heat). Praying this works (I will bump up the dosage in a couple weeks). My quality of life, and my marriage, are worth any risks. Thank you, Premarin! F 49 4 days
0.3mg
1/13/2018
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 3  Had a total hysterectomy Waking up often during the night, restless legs syndrome, hot feet & hands thinning hair, weight loss, I wish there was something else to take that won't have the side effects this medication has...Very worried F 60
.0625 1X day
11/14/2017
 5  Hysterectomy (Uterus & Ovaries) None that I noticed The hysterectomy that I had no choice but to undergo force me into surgical menopause. I feel horrible I had no energy I was having hot flashes night sweats and I would gained 35 lb and 8 months. I had never weighed over 110 lb before the hysterectomy. Doc first prescribe me Estradiol as hormone replacement and it didn't help at all. I went back and my doctor prescribe me Premarin and it made a huge difference in my life. With Premarin the hot flashes, night sweats, moodiness, old feeling went away. I also lost 30 pounds within 6 months without changing my diet. It's like it made my metabolism come back to normal. Risk with Premarin are minimal no matter what they've been saying in recent years I've had friends that have been on Premarin since they were in their twenties after hysterectomy and they tried to switch them off of it and it did not go well for them either. Don't be afraid of the Premarin it will definitely make you feel better and help to get some weight off of you. F 46 2 years
.625
8/4/2017
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 3  Total hysterectomy 18 lb weight gain with no change in diet or level of activity and heart palpitations I wake up every 20-30 minutes with horrible night sweats if I don't take this medication. I tried the lower dose but it wasn't very effective. So now I have to decide: do I want to be overweight and miserable or be an insomniac and miserable? I wish there was another way. F 52 6 months
0.9
6/11/2017
 3  Surgical menopause @ 43 Previously on a natural hormone drops for 5 years. I now take .625 MG of Premarin once a day. This change definitely helped dryness, yeast infections and roller coaster mood swings. I now have facial hair that I must keep and eye on but the worst is my weight. This has become a serious issue, I am now 50 pounds over weight! :( I still have some irritability and not the energy level I once had. I am wondering if my dose is too low, or may need to add testosterone, hoping that might help. Would recommend over natural hormone drops F 50 2 years
.625
5/8/2017
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 5  Oophorectomy 2016 I had a partial hysterectomy in 1997. Had a large cyst on my ovary and had a Oophorectomy in December 2016. I immediately went into full menopause, I had experience some issues with the partial but nothing major but after the last surgery, crying spells, hot flashes, depression, not sleeping, you name it i experienced it started. My doctor initial started me on 1.25 mg once a day of the Premarin and that worked for a short time but then the hot flashes got worst so he up the dosage to 2 a day of the 1.25mg and I haven't experienced any issues since. My sex life is even better since I started taking the medicine and I am so glad since my husband is younger than me. Premarin saved my life and my marriage. I rather deal with my husband sexual appetite than to deal with him not being able to touch me because I could stand to be touched because the hot flashes, depression and crying spells were so bad. F 48 4 months
1.25 2X day
3/22/2017
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 5  Severe post menopause symptoms None Helped me so much to be happy, calm, no hot flashes or night sweats F 63 1 years
0.625
3/22/2017
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 1  Postmenopause I was prescribed Premarin because sex became painful, and my doctor said that it would help rebuild my vaginal skin I also had reacurring UTI's due to the change which would cause bacteria to easily reach my uretha. I tried it twice stopped saw spotting. Tried it again stopped and experienced a full five day period. I'm terrified of HRT I have a sort of mild pressure headache and neck pain for months. My mother is in a nursing home due to HRT she has ZMS, DEMENTIA, STROKES, GALLBLADDER REMOVED Therefore I'm terrified of these synthetic drugs and what danger it may cause to my body in years to come. Menopause is a tight cookie but I rather be safe and alive. Just by the few insertions I took I'm terrified still.should I be worried? How long does Premarin stay in your system and does the estrogen dissolved after a while F 55 4 times
30
2/20/2017
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 5  pre-menstral to keep organ health No side effects ever.... Feel wonderful and never had any night sweats or mood changes post-menopausal Excellent hormone replacement therapy... Feel so young and look it, too.... F 71 30 years
1.25 1X day
2/17/2017
 5  To keep organs & hormones balanced. I feel wonderful. no mood swings, skin looks like <57 yr. old, bones strong, Libido great, cardio great, no cancer, still get period monthly (love it), no pain and feel extremely alert..! I take Premarin 25 days and last 10 days together with 10 mg medroxyprogesterone. Never went through menopause. Feel wonderful and strong and vivacious. Stopped for 1 month and thought I was headed for the grave. Immediately began taking and will never quit. I know I look younger than most all women my age and totally believe it's because of the combo of Premarin & Medroxyprogesterone.. along with nutritious diet & exercise, no smoking and very little drinking of wine. I am a health nut. How can I convince my Doctor to let me stay on this and make sure my Insurance covers it??? I know I'll shrivel up and die without it. No joke! F 72 30 years
1.25 mg 1X day
2/15/2017
 5  Menopause symptoms No side effects at all only positive relief of symptoms. Feel 15 years younger since taking Premarin. My hair is thicker and fuller, my skin is amazing. I work out daily with no pain. Sleep 8-9 hrs each night. This medication has been a God send, no menopause symptoms at all. F 54 4 years
1.25mg
2/11/2017
 1   My legs, foot, ankles hurt. Feel legs very heavy. Premarin help with hot flashes, but side effects are making me to discountinue it use. F 51 1 years
1X day
2/5/2017
 3  trying it for stopping hair loss dry skin No side effects yet has any female taking Premarin for dry skin and to stop hair loss? F 65 1 days
30
1/26/2017
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 1  menopause Breast cancer Now after surgery and radiation I should take estrogen blocker Arimidex for 5 years . Avoid F 60 4 years
625
1/26/2017
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