PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  surgical hysterectomy I was very happy on the pill. I am wondering why I am having chest pain and dizziness AFTER stopping it suddenly? My doctor wanted me off of them and so a year ago, I went down to 0.625 mg a day. Then I just stopped about a week ago. F 64 21 years
1.25 mg 1X day
12/11/2010
 2  FAH due to ovarian cyst Headaches, WEIGHT GAIN, aches, blurry vision and dry eyes. Have jusr reduced dose to 0.3 - so far not helping.... F 47 18 months
0.6 1X day
12/6/2010
 1  Surgical Menopause/Oopherectomy I'm 29 Years old and have just had my ovaries and fallopian tubes removed because I had tumors that kept coming back...this was my 5th surgery since I was 14yrs old to remove tumors... I am depressed, have migraines, night sweats, insomnia, hot flashes, mood swings, and weight gain...i'm afraid to take the Premarin that my doctor prescribed for me @ 1.25mg...Do I have to take anything? .... I'm tired of living like this but I don't know what to take that isn't going to make me feel worse... PLEASE HELP!!! F 29 0 days
1.25 1X day
12/6/2010
 3  HYSTERACIMIA PREMARIN WAS WORKING GREAT WHEN I FIRST USE IT. THAN 6 YEARS LATER IT TURN ON ME VERY BAD LEG PAIN LOWER AND VERY BAD LOWER BACK PAIN HAD BAD CRYING BOUTS HAD GOTTEN BLOOD CLOTS IN STOMACH HAD TO GET OFF DON'T HAVE ANY OF THESE SYSTOMS ANYMORE. EVEN THOUGH I HAVE BEEN OFF IT FOR 4 YEARS I DID FEEL GOOD WHEN I FIRST TOOK IT. I AM NOW VERY TRIED SKIN ALL DRY HARD TIME SLEEPING AND VERY MOODY. WHEN I DID HAVE TO STOP THE PREMARIN COLD TURKEY I WENT RIGHT INTO MENOPAUSE HAD ALL MENOPAUSE SYSTOMS TERRIBLE. YOU HAVE TO WEEN YOURSELF OFF. HOPE I HELP SOME PEOPLE REGARDING THIS DRUG. F 54 13 years
6.25 1X day
12/2/2010
 1  menopause My doctor gave me Premarin .625 late in the summer. Shortly after that I had some back pain and I thought i had pulled my back. Then I would have bouts of nausea and dizzyness. I didn't put any of this together with taking the premarin :(. so i have been feeling this way for a while. then last night i was sitting in the chair crying because i just felt so bad and my husband asked me where i felt back at and I said it feels like i have menstrual cramps. At that point it dawned on me! it could be the premarin. i logged onto the computer and sure enough i had all of the side effects. today i cut the pill in 1/2 and now i'm searching for how to get off of this stuff. i found this website. has anyone here ever quite cold turkey? i'm afraid! F 54 3 months
1X day
12/1/2010
 1  Hot Flashes My chest began to hurt within hours of taking the first and only pill. Within 6 or 8 hours I felt like I was having a heart attack. Yes, I am seeing a cardiologist and spending a whole lot of money checking out my heart and lungs....not finding anything wrong there. I am convinced that this drug has had a terrible effect and possibly set off a complete change in my body. Doctors are finding it hard to believe that Premarin did this but the more research I am doing the more I believe it. I had none of the heart symptoms that continue to plague me....for the last 7 weeks....prior to taking this medicine. F 46 1 days
.3 1X O
11/21/2010
Email
 5  total hysterectomy at age 30 No side effects. MD has changed dose from 1.25mg to 0.625mg to 0.9mg now. I feel best with 1.25mg. I look at least 10 years younger than my age (good genes?) and thick head of hair. Tried patches and Estratest before premarin and had continuous hot flashes. Started the Premarin and they stopped within an hour. I do not ever want to be without the Premarin. F 51 20 years
.9 1X day
11/9/2010
 2  complete hysterectomy been taking premarin for ten months and thought i had poison ivy due to rash on arms, legs etc. depression so bad i didnt leave my bed for days , no shower or anything just slept . extreme mood changes, very poor impulse control, re-triggered my gambling addiction, pawned wedding ring and took out multiple loans etc. pain in legs, swelling , cramps in legs, inability to wear contacts comfortably. dry eyes , terrible migraines , feels like i am in another dimension , disoriented, dizzy, terrible knee and joint pain , hips. insomnia.flu like symptoms. suicidal thoughts, homicidal thoughts, crazy distorted thinking.gained 40 lbs. NO sexual desire vaginal dryness have gone off premarin for 3 weeks and am experiencing hot flashes but not much else. my knees still hurt and i cant sleep, very irritable, depressed, hopeless. F 45 10 months
1.25 1X day
11/5/2010
Email
 1  Total Hystroectomy Migraines, severe depression/mood swings, leg camps, loss of sleep I have talked with my doc about my side effects and she would just lower the dose. I actually cannot take this med any longer. I stopped taking it on Monday. Hopefully I can take back control of my life. So far no hot flashes. If I end up having them I will deal. F 35 3 months
1.25/.625 1X day
11/5/2010
 5   I have experienced no side effects The day after a total hysterectomy my doctor suggested that if I took Premarin I would feel better. I have taken Premarin for over 28 years. I have not gained weight. I am flexible, have lots of energy, do not have trouble sleeping or with mood swings or memory. Intimacy has not been a problem. F 70 28 years
.625 1X day
10/25/2010
 5  hysterectomy, removal of ovaries Can't think of a single side effect I am, of course, worried about the report that came out today about the dangers of progestin and estrogen and the risk of breast cancer. I thought that estrogen alone was not as much of a risk. I was diagnosed with osteopenia last year, considered increasing estrogen but decided to stay at the lowest dose. When I do not take Premarin - i feel like I could bite a 10 penny nail in two! I am 54 and figure that I would naturally go through menopause now, so I may wein myself off this year. Premarin made my life better. F 54 11 years
.325 1X day
10/19/2010
 5  Vaginal atrophy, low libido No side effects experienced. Intercourse was so painful, I thought I would never have sex with my husband again. No lubricant helped and my urethra was irritated and torn. Total reversal of these symptoms! I love this therapy! Changed our lives! F 57 3 months
0.5g 2X W
10/10/2010
 3  TAH/BSO weight gain. night time leg cramps. sore leg muscles. irritability. sleeplessnes, tiredness I am trying to decide if the side effects are worth continuing with the medicine for. I had TAH for severe endometriosis, and I just seem to have swapped one nightmare for another. I would like to hear from anyone who may have had similar symptoms, and to know what they did F 41 8 months
0.625 1X day
10/2/2010
Email
 2  after complete hysterectomy age 48 mood shift, unable to shake depressive thoughts, very low energy I tolerated it as long as I could and then went back to MD -- he switched me to a patch -- the relief from symptoms was within a day or two, like a cloud had been lifted - the patch was great and I used it for years with no side-effects -- I also had a bad reaction to Ortho-Novum years ago, enough that the reaction was labeled an allergy, "maybe" to the estrogen component F 70 14 days
? 1X day
9/18/2010
 5  hysterectomy none I have had back surgery and I feel Premarin is keeping my bones strong. My DECA scans are perfect. I am the only one of my friends that doesn't have osteoporosis. They do not take Premarin. My skin is young, and I feel great. I am 71 yrs. old F 71 17 years
0,045 1X day
9/4/2010
 5  complete hysterectomy NONE,that I am aware of. Recently I had to have a breast biopsy, and I was told to stop taking my premarin. I did. It was not cancer, we were blessed but when I wanted to go back on my Premarin, my Dr. suggested not doing so,because I had taken it for so long. I felt so good when I took it. I did not feel as tired, I had energy. I have lost a very few pounds since I have been off the medication but I believe I could manage those pounds. My joints were more flexible when taking Premarin. Now, I get no sleep,the hot flashes are unbearable, the heart palpitations are common. I just really will talk to my Dr. at this point about a dosage every other day possibly. I have been off Premarin for over 90 days and I feel like I am older than 65, I want it back. Recently I bought Black Cohosh to maybe help. I had more problems with that over the counter supplement than I ever had with Premarin. F 65 22 years
.065 1X day
8/23/2010
Email
 2  Irritability post partial hyst Excessive weight gain, even though my eating habits have not changed, tired, headaches F 50 1.5 months
1X day
6/19/2010
 1  Hysterectomy, then Ovaries removed Dibialiting Headaches, rapid aging, depression, anxitey, weight loss Had total hysterectomy due to endo, then ovaries removed 6 months later due to severe scar tissue. Doctor put me on 0.625 and felt great at 1st but gradually started getting dibialiting headaches, then depression, anxiety and weight loss. I also felt like I aged about 5 years in 9 months. Went to female gyno who also had ovaries removed and told me to throw Premarin in the trash. She told me about Estrogel which is the HRT that she is on. I tried it and within 2 weeks felt like my old self again. Headaches are gone and my skin and hair look great!!! I do have a little anxiety but nothing that interferes with daily activites. I run 4 miles 2 times per week, bike 15 miles 3 times a week and swim twice per week. I am 47 and feel so great that I've actually signed up to do my 1st Triathlon. That would have NEVER happened if I was still on Premarin. Plese throw your Premarin away and ask your Dr. to prescribe Estrogel 0.06%. M 47 9 months
0.625 2X day
6/8/2010
 5  hot flashes No side effects that I know of, been taking it for over 10 years, but I now have high blood pressure and thyroid issues. I have decided to stop taking it cold turkey, any suggestions from anyone if this is ok. No side effects that I know of, been taking it for over 10 years, but I now have high blood pressure and thyroid issues. I have decided to stop taking it cold turkey, any suggestions from anyone if this is ok. F 52 10 years
.09 1X day
6/5/2010
Email
 5  Complete hysterectomy at age 33 No side effects attributed to Premarin At the urging of my family doctor, I decreased my dosage to .9 and two years ago to .625. I haven't had problems with hot flashes, sleeping, weeping episodes, etc. My bone density is great, my skin good, and people don't believe my age. My GYN is OK with my taking Premarin. I'm scheduled for a total knee replacement in just over three weeks, and earlier this week, the orthopoedic surgeon told me that I had to stop the Premarin immediately. Cold turkey. Today is day two. I have very stressful circumstances in my life, so the thought of adding more is somewhat frightening. However, it pales in comparison to the potential of a blood clot after surgery. It's something I must do. I do have the option of going back on it later on if it gets too bad. Who knows? I pray for strength during this time and wisdom to know what to do later on. F 67 30 years
.625 1X day
6/4/2010
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