PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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 Type: Rx Drug

  

PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  menopausal symptoms My mother was prescribed this for 11 years and it GAVE HER BREAST CANCER. If you still have your ovaries and you take this, you run a high rist of breast cancer. If you have had a hysterectomy with ovary removal than you should be ok i think?? F 11 years
4/19/2008
 5  hrt (hypogonadism) only good side effects including weight loss ! (BMI was over 30) My symptoms before trying it were : night sweats, muscle pain, osteopenia, high calcemia, high T4/TSH, libido decreased. I'm intersex (delayed puberty due to low LH-hCG bioactivity, partial gonadal dysgenesis) 41 12 weeks
4/18/2008
 4  total hysterectomy weight gain right around the middle despite diet and exercise, joint pain, blurred vision I found this site looking for answers. After reading 50+ negative comments and the 2 or 3 positive ones, I am tossing this drug. I am thrilled to see that I am not the only one with these symptoms! Whoever created this site.. THANK YOU! F 40 6 years
4/18/2008
 4  complete hysterectomy major weight gain, tire around the middle I had a complete hysterectomy on ll/15/07, there was a mistake made and I ended up with my ureter cut. So a second surgery was required immediately. I did not have any hormone replacement until about 2.5 weeks after surgery. I went back to my doctor he prescribe climara patch, which would not stay on and caused my skin to burn. So the doctor switched me to premarin .625 and now I have a tire around my middle. I excerise six times a week for one hour since I was release from the doctor's care 1/8/08. I also have good eating habits, I have not lost one pound, instead I have gained. Reading everyone else's comments have given me the tools to make some changes. thanks F 51 58 days
4/10/2008
 5  complete hysterectomy at age 40 None at all! I stopped for awhile when all the scare studies about estrogen came out then asked to go back on them after a couple of years of horrible hot flashes and depression. I feel great with the low dose of this pill. Take it, it works! F 56 16 years
3/26/2008
 3  TAH CHRONIC TIREDNESS LOW SEXUAL LI ONLY STARTED TO TAKR PREMARIN YESTERDAY AWAITING ANY POSSIBLE SIDE EFFECTS HOPEFULLY NONE FEELING QUITE CONCERNED AFTER READING COMMENTS FROM OTHER PREMARIN USERS F 54 2 days
3/26/2008
 4  Had a hysterectomy hair loss, weight gain, stiff legs and joints, I was put on Premarin .625 after a hysterectomy, it made me feel bloated, my breasts felt heavy, my stomach swelled, weight gain, my hair grew thin and balding, I was breathless, I came off it after 9 years and it was awful, dreadful sweats, skin dry mind was muddled, suffered this for 2 years, and went back on it but I would rather find a natural alternative to premarin. It does make my skin look younger, though and gives me more energy. F 65 15 years
3/23/2008
 5  complete hysterectomy No negative side effects I have had none of the side effects others have mentioned. I feel the benefits far outweigh whatever negative press Premarin may get. F 58 11 years
3/10/2008
 3  Complete hysterectomy Vaginal dryness and thinning of the skin around the vaginal areas. I have tried stronger strengths and have stopped taking it because I have felt so bad while taking the Premarin. I am now taking 325 dose. Actually I started searching the web to see what was possibly making me feel so "lifeless" now. I could actually stay on the couch all day long. No interest in anything and there is no other reason not to be interested in things. I'm just tired all the time! I sleep great with the help of melatonin and eat well too. F 44 7 years
3/9/2008
 5  Hot flashes none I feel great and look much younger than my years... F 66 20 years
3/6/2008
 3  complete hysterectomy age 16 bloating, swelling of joints, skin discoloration, hair loss, breast tenderness, vaginatis, mood swings, did not realize how bad this drug made me feel until I quit taking it two years ago F 46 29 years
2/24/2008
 3  Hysterectomy, doctor said I need it I am not sure if these are side effects from the PRemarin or from the Nitrofur they were giving me--weepiness, depression, anxiety, weird thoughts in my head. Sunday night, I had the adrenaline rush, fogginess and all. That was after my second day of Premarin. Sunday and Monday I was in pain(bladder) and they thought maybe it was a UTI. On the way to get the medicine, I had the adrenaline rush feeling again. That was the third day of Premarin and my synthroid. Monday night took the antibiotic. Tuesday, woke up with leg pain, and all week, the tingling and numbness and all in my legs was there, except Wednesday, until Wednesday night. Thursday, didn't take the Premarin, extreme fatigue and the head stuff started. Was still on the Nitrofur. Friday morning, head stuff was weird. Saturday, the head thing was fierce, felt like creepy crawlies, and extreme fatigue. They have all told me, oh it is just a viral infection attacking your nerves. Went to the ER Saturday, and they did a CT scan, t Premarin 1.25, Nitrofur was 100 2 times a day, and the Synthroid is 75 mcg. I am really trying to decide about the Premarin and what to ask my doctor when I go back to see her. We are waiting also to see if I have an adrenal gland dysfunction and/or carcinid tumor. I had Ovarian Cancer in 2006 but they got everything and took everything out and have not had to have chemo. F 38 5 days
2/20/2008
 5  Hot Flashes, Sleepless nights I fell wonderful. I can finally sleep and hot flashes are gone. I have also lost 6 pounds in one month. I have been on premarin .3 for 6 weeks and am very pleased. F 51 6 days
2/14/2008
 4  hrt Hard to say because I was taking Provera with it as well F 49 4 years
2/8/2008
 5  Had surgery when I was 38 years old Had no side affects until 8 months ago when my dr took me off it, then my hair started to fall out and my skin became so wrinkled! I have gone back on 1/2 dose, but plan to go back to full dose. I love my hair and the skin I had, want it back! I'm 69 and I'll continue taking 2.25 mg for the rest of my life. I'll continue to take it. Started taking it when I was about 39 years old. It kept my skin beautiful and my hair didn't fall out until I stopped taking it. F 69 30 years
1/29/2008
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 5  total hysterectomy I coulden't sleep after having my hysterectomy so doctor put me on .625 premeran apex three weeks after surgery. I go off of it on the 25 of the month and start again on the first. I heard it was not good for you to be on premarin very long so apex 5 mo ago I started splitting mine in half. My hair is falling out my head is sore and have been having more cramps. I am 5.2 and weigh 135.I have not had any complications except my hair. I feel great, play golf and do yoga. I am going back to taking my.625 premeran. F 77 25 days
1/20/2008
 1  Excessive menstrual bleeding Hunger then lack of hunger within a matter of days, trouble sleeping, feelings of sadness and hopelessnesses, almost depressed, anxiety, my hair started falling out when brushing or washing, general tiredness and feeling not like myself. My Gyn put me on Premarin after a laparoscopy to treat 4 weeks of menstrual bleeding, his thinking was that it would balance out the hormones to stop the bleeding, was concerned after researching that Premarin can increase the size of uterine fibroids as just discovered that I have many (which may be causing the bleeding) after doing further research, especially into how Premarin is manufactured decided the risks and side effects outweigh the benefits and took myself of the tablets today, hoping my mood will now get back to normal. F 36 7 days
12/21/2007
 1  total abdominal hysterectomy Allergy type reactions. Weight gain,moodiness. Nervousness,nausea,headaches,swelling...feeling unwell....I could go on and on! Awful stuff and there are so many better alternatives! This drug should be banned! Not to mention how it is made! WOMEN TAKE CHARGE OF YOUR HRT! ASK FOR SOMETHING ELSE! I STOPPED PREMARIN AFTER 5 YEARS OF A STUPID DOCTOR PUSHING IT ON ME...NOW I AM TAKING ESTRADIOL! MUCH BETTER! F 35 5 years
12/20/2007
 4  Diagnosed with Turner Syndrome Wen off the Premarin: Emotional, Hot flashes, Dizzyness, Personality disorder, Depression, unable to think clearly or stay focused. I was diagnosed with Turner Syndrome when I was 12 years old in 2000. I started taking Premarin in 2003 starting at .3MG than to .9MG than back down to .6MG. I havent had any serious side effects except for heart palpitations every once in a while, but when I dont take my medication its worse. I get dizzy, my blood sugar drops immediately, hot flashes, one minute I am happy, the next Im suicidal. I get major mood swings and I become depressed permanently until I go back onto my medication. F 19 4 years
12/4/2007
 2  hystorectomy had a hystorectomy in 2003 with 1 partial ovarie left, had that removed 10/25/07, now its 11/10 and have had the worst symptoms. Hot flashes constantly, night sweats, fatigue, body aches. my dr put me on.625 premarin a week ago, no change yet almost feel worse, very tired, just icky. How long before i feel relief? F 39 1 weeks
11/10/2007

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