PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

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PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Total Hysterectomy Unresolved Peripheral Edema. Been off the medication now since October. They switched me from Premarin to Estratest to Climara and currently off of all HRT till after cardiac testing is done. Never had a single problem with edema or anything till starting this medication. Have been told that the problems will never resolve. Went from 144 lbs to 167 lbs. Bra size 36C to 40DD! Unless anyone wants the benefits of extra large breast then I would suggest they stay away from the medication. Or FDA should get off their A$$ and figure out why it causes this is some women and some women it causes no issues. There is a missing link somewhere. They just need to take the time and figure it out! Spoken from a licensed NURSE mouth! F 37 5 months
11/29/2009
 5  total hysterectomy tried bioidentical because they were to be so much better not, after several months of chest pain ,heart palpatations, increased blood pressure and increased pulse rate I went back to Premarin and all those side effects went away, will not change again. Do not be fooled by bioidenticals if you have any heart symptoms could be that. I have not had any problems since going back on Premarin. F 41
11/22/2009
 5  hysterectomy at 45 I've never had a side effect. The doctor suggested I stop taking it and immediately felt horrible. I also gained 10 pounds & my blood pressure went up. I've never been on blood pressure medicine but now I am. I went back on premarin & now have a GYN appointment to fight for my right to remain on it. I know the risks but there are risks in everything - this works for me. F 64 19 years
11/10/2009
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 5  Total hysterectomy at age 26 I bled for 8 months straight. Very heavy with huge clots. None of the meds that was prescribed worked. I had to have everything removed except for one ovary. I went for 8 months not taking any kind of hormones. The doctors were hoping that my 1 ovary would kick in and work. But it did not. My body began to swell and just touching my body anywhere with the slightest pressure caused me great pain. I was then put on Premarin. The swelling went down, no more pain. I have been on it since 1986. My doctor wanted to lower my dosage. We did and all the pain and swelling came back! And we tried this over the years several times. Always came out the same with the same results...all BAD!. I told her that I will stay on it for life. I will not go through that again!! F 49 23 days
10/10/2009
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 1  hot flashes,depression Hot flashes increased,leg cramps,nausea,severe heart palpitations,dizziness,confusion,extreme fatigue (in bed all weekend) This is an awful drug..and I was only on it for three weeks! I had such bad side effects that I had to go to the ER (thought I was having a heart problem)..and I cannot afford this. I am still really sleepy, 3 days after stopping.I would never recommend this drug...there are better alternatives. My MD says all these problems were not related to the 0.625 mg. Premarin...but why do I feel better,since stopping??? F 53 21 days
10/7/2009
 1  Haven't started yet, and won't now Terrible hot flashes. Night sweats, mood swings, depression, ect. I had a hysterectomy in 2001 and has been dealing with all of the terrible symptoms since 2003. Last week I decided to maybe try Premarin after being pushed for years by my Doctor to at least try the smallest dosage,0.3MG. I filled the RX but after reading all of the negative press I'm slam dunking them like right now. I have managed for all these years, might as well keep on. F 52 0 days
9/30/2009
 1  DESPERATE..TYRING AS MY LAST OPTION I have suffered most of the side effects severly already ...can it really get any worse than ready to stand in front of a moving train ??? if yes.., then its death by chocolate and champagne 24/7 Started "Premanin today !!! ((((praying for some glimmer and SAFE return of the once sane happy capable woman and life in me)))) .....I'm in total contradicted FEAR :(((...BUT ITS ALL I HAVE LEFT. THAT I HAVE NOT TRIED !!! However my deep emotional logical FEAR is gripping me, as my younger sister and aunt have had and survived breast cancer. If only there was a successful clear and simple way to simulate balance our own hormone producing glands.........but every woman's body and life paths have set personal patterns which are almost impossible to unravel pinpoint a clear pathway to true hormone balance and health throughout our life. Have other Women out there felt this bad and in FINAL DESPERATION go directly against ones own logic FOR SOME SORT OF QUALITY TO LIFE ...having to fin I'm 54 now with very *Low estrogens, *MENO-INSANE, very unhappy, single(no interest in a partner) overweight not from eating too much, unfit, chronically depressed, aging rapidly, feel like a cold fat unattractive vegetable, cannot concentrate or work with little interest clarity, poor memory, un sociable, lost confidence, no motivation for anything or positive outlook, always very tired fatigued.....feeling like everything has shut down, body has just given up, crashed, stoped with no fuel left, train wreck, Elvis has left the building :(((. (At 50yr I finally sarcome to a Hysterectomy leaving one ovary after battling multiple fibroids, very *High estrogens dominance, years of heavy emotional stress fatigue. However felt I was still quite intelligent,kind caring, creative talented, hard worker,outgoing with a real zest, strong assured confidence, quite attractive slender feminine nice body, thick hair, thoroughly enjoyed fulfilling sexual intimacy rewarding life) Now I have spent all time efforts money on naturopaths health supplements advise talking listening reading studying comparing......now in my final desperation worn down/out, have finally given into dreaded *Premarin .625mcg that I SAID I WOULD EVER TAKE ( my mum in desperation seeing me try so hard with everything natural and suffer much for so long finally took THE *P SCRIPT ( I had kept for my last and final desperate measures ) to the chemist today and filled it for me, she with hope tears and hug just try it F 54 1 days
9/26/2009
 3  Dry Vagina - itching in genital are
9/17/2009
 5  Total hysterectomy at 39 I had no side effects and had taken it for 25 years! .065 dose. My doctor took me off of it about 1/1/2 years ago, as he said they believe it increases blood pressure. High blood pressure runs in my family anyway, but I do take medication for it, its borderline.Since stopping premarin, I have terrible hot flashes, hair loss and getting flabby around the middle, despite my working out, and more hair on my face. I am going back to the doctor tomorrow and want to go back on it. I never gained weight from premarin and I am going back on it!!!! F 66 25 years
9/8/2009
 1  will not, take plant-based hrt i don't understand how so many women could blithely take this drug that is produced from so much suffering and death from the premarin mares and their foals. there are other hrt's that are produced without the awful impact of this drug. and lobular cancer is associated with taking of premarin. F 54
8/29/2009
 5  menapause/osteo migraine, but this is genetic and based on the normal hormonal cycle anyway for members of my family. I had no side effects and felt wonderful. Full of beans, fit and healthy. Last year I did have abnormal cervical cells which were checked OK. Being checked again shortly. Just recently taken off premarin by doctor after increase in BP after heavy stress at workplace, and prescription availability problems on NHS. Put on Femoston. Suffered night leg cramps, aching, dizziness, dulling of brain, nearly had a road accident and I cannot sleep anymore because of the cramping of my legs, which also have sensations like insects crawling over my skin, and assorted sudden pains everywhere. I want my premarin back! I'm off to the doctors to sort things out. Love it! F 64 15 years
8/20/2009
 3  MENOPAUSE WEIGHT GAIN (15 lbs.). UNABLE TO LOSE WEIGHT DESPITE DIET AND EXERCISE. MY SKIN AND HAIR WERE GREAT PLUS NO NIGHT SWEATS AND WAS ABLE TO SLEEP. LESS HEART PALPITATIONS. ALTHOUGH IT WORKED ON ALL MY MENOPAUSE SYMPTOMS, I COULD NOT STOP EATING (THIS STATED AT THE EXACT TIME I STATED THE MEDS). AND IT HAD RAISED MY BP SLIGHTLY BUT NOTICEABLY. ALSO HAD MORE UTI'S AND PAINFUL BLADDER WHEN FULL (NOT SURE IF THIS IS RELATED - BUT I HAD A NAGGING FEELING THAT IT DID). AM THINKING OF GETTING OFF DUE TO ALL THE NEGATIVE INFORMATION ON THIS MEDICATION. F 53 6 months
7/29/2009
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 3  Complete histo- I was worried about heart disease and cancers so against my Dr's advice, I stopped my .675 Premerin dosage. I was fine at first, then, maybe two months later, I started really feeling it...terrible hot flashes, brittle nails, lots of hair loss. Maybe I should go back on?? I have been bruising very bad on legs and feet. Breast cancer runs in our family. I am trying Estroven..first day is today. Hopeful! I think more info should be available...more options also. Not just our doctors pushing manufactured drugs b/c of the drug companies and the money they pay..... F 37 18 months
6/14/2009
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 1  total hysterectomy Horrible leg swelling, then whole body swelling after only 7 days on prescription. Ending up in ER to rule out DVT, on diuretic for over a month now trying to get edema under control. Will never touch hrt again, prefer to wake up sweating numerous times a night. Dr didn't recommend, I had asked for hrt since I had gone without for over a year since sx and the sleepless nights were getting to me. I have decided I can live without a full nights sleep. F 47 7 days
5/16/2009
 5  Total hysterectomy age 44 Mostly side effects when I didn't take it. Intense crying episodes. I do have concerns about it with the breast cancer thing..but do not know of any negative side effects Initially took 1.25 decreased to 1.0 & 6.0 over time now taking .3 every other day for 2 years. F 68 20 years
4/26/2009
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 2   Hot flushes,trouble sleeping, weight gain, hair loss,breast pain,nervousness,facial hair. When I first started taking it I felt fine but now 13 years on the side effects are increasing especially hair loss which I am finding very distressing. F 52 13 years
4/20/2009
 4  total hysterectomy aged 32 i was given a total hysterectomy at 32 after years of suffering severe pain due to endriometrious .i would total recommend this type of hrt apart from a little weight gain which could be age or diet related anyway , my hair skin and health are better than they have been throughout the earlier part of my life . i feel this is a very good hrt and ive been very happy with it . F 44 11 years
4/2/2009
 5  hot flashes none I just afraid of the cancer threats with taking this medication. F 55 4 years
3/30/2009
 4  Total Hysterectomy weight gain-15 lbs., tingling, joint pain, stiffness and exhaustion I can't afford night sweats due to diabetes-and know Premarin helps me look younger, I have tried going without before and didn't like results. I take insulin and synthroid so am confused as to whats causing what. Have been on .625 Premarin-after reading posts I will try and decrease the Premarin to see if any improvements. Sugars and thyroid tsh are great. F 55 17 years
3/20/2009
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 1  Total Hysterectomy 44 yr old, normally in great health. After 1 year on Premarin I began to have constant pain, throbbing and swelling in my legs. I suffered for months. I suspected that the HRT was the cause. Finally I decided to stop the Premarin and within 4 days of stopping the meds all leg symptoms were gone! I will NEVER EVER take this med again. F 44 12 months
3/17/2009

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