PREMARIN Reviews (ESTROGENS, CONJUGATED)

Average Rating: 3.4 (505 Ratings)

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PREMARIN  (ESTROGENS, CONJUGATED):  This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREMARIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PREMARINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  total hysterectomy kept ovaries I have gained 12 lbs. in 3 years-swollen breasts,spare tire and fat around the stomach-feel very bloated and retain water.I have always been normal weight and no excersize helps the weight around the middle. I had very bad hot flashes,chills,weepiness and anxiety after my hysterectomy. My Dr. said I still wasnt in menopause -still producing estrogen at first. Tried soy and herbal remedies-they helped reduce the hot flashes a bit for a while but I still felt very nervous and like crying all the time. Finally got the courage to try Premarin-dr. said it would help and the awful hot flashes stopped. I feel somewhat better mentally. I cut .45 in half and take it daily but wonder if the full dose would be better. Cant stand the weight GAIN. always had been slim.It does keep you looking younger I think-my skin is much smoother and younger looking than a friends who never took hormones. I worry about breast cancer but quality of life is better while on Premarin so I guess its worth the risk. F 60 3 years
2/26/2009
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 1  hysterectomy I had been on Premarin 1.25 for 21 months. Everything seemed to be going well, yes I put on 45 lbs but thought it was the hysterectomy. In August I started having severe foot pain and unbearable leg cramps. I bought several pairs of shoes trying to relieve the pain. Numerous trips to the doctor, all kinds of blood work, and on and on. I was in so much pain with horrible swelling the last month I could no long stand it. I started a Chiropractor and again nothing helped. The doctor had thought it was a blood pressure medication they had me on for high bp, I stopped taking it but the horrible pain and edema continued. Finally one morning I said "I am going to stop taking the Premarin, and you know what the swelling left, the pain in my legs were gone, and I felt great. I told the Doctor I had quit the premarin and he said he didn't think it was that but it certainly worked. He gave me HRT patches to wear but I am not starting them unless hot flashes begin. I can not tell F 51 21 months
2/24/2009
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 4  Total Hysterectomy - Age 38 Slight Memory loss (but always been a bit scatty!), mood swings, a little weight around my belly I can honestly say since having my hysterectomy and taking Premarin (1.25mg now - the lower dose originally made me feel very tired) I have felt so much better. Having suffered since my early 20's with endometriosis and adenomeyosis I feel rejuvenated. My skin is glowing and I look and feel great. Lucky to conceive twins at the age of 37 with the help of IVF, I have a pain free life and the slight side effects are a small price to pay and do not worry me. I feel pain free for the first time in 15 years and enjoying my fantastic life. F 40 2 years
2/17/2009
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 4  Total hysterectomy at age 25 none I had to have a full hysterectomy at age 25. I dealt with some depression as a result of it. I dont feel that the pill caused the depression, I think it was just me getting usto the idea that I will never have the possibility of having a child of my own DNA. I thought it may have ben the drug causing my depression so i quit taking it. I received sever hot flashes and mood swings. Once i started taking the pill again, I leved out. I would like to warn younger people who have had their ovaries removed thinking of quitting hormone replacement. Please consult your Dr. before stopping, your risk of developing osteoporosis is greatly increased. The benifits greatly outway the risks for me having to take hormone replacemnt at such a young age. I am no Dr. but thats what my Dr. told me. F 28 3 years
2/13/2009
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 1  Hot Flashes and Bone Concerns Increased my eating habit which lead to weight gain 13 lbs in 7 months. Sleepiness and fatigue. Very sore breast. Although it took away the hot flases this pill has to many dangerous side affects. If you are considering this medication please read side affects very carefully. I would never recommend to anyone. F 50 7 months
2/8/2009
 4  Totaly hysterectomy on 1/29/08 Total hysterectomy due to endometriosis, bleeding in fallopian tubes and cysts on my ovaries. After that I experienced dry skin, aches in shoulder & knee joints, and hot flashes. My body suddenly felt very old. Sexual feelings/urges were completely gone. I felt like I'd been castrated, it was so apparent that a part of me was missing. After 2 week follow-up appt, the MD placed me on 0.625mg of premarin. However, the physical problems persisted. In my 3 month follow-up visit, I asked for an increase in dosage and the MD changed it to 1.25mg. The problems went away in 2 days and I felt normal again. But in the following 3 months after my 2nd appt, I gained over 30 lbs!!! I have concerns about the abuse of mares in the maufacturing of Premarin. I'm also greatly concerned about it's risks for causing heart disease, breast cancer, etc. But even though I'm fat, I feel more normal and able-bodied with the Premarin, than without it. Still, I'm thinking about asking the MD to lower the dosage one notch just to cut health risks and see how my body adjusts. And I'm trying to take off the weight. F 48 1 years
2/6/2009
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 3  hysterectomy bloating weight gain acne took away hot flashes M 52 10 years
2/4/2009
 5  total hysterectomy I gained weight on the 1.25 when my MD cut them in half to .6 I lost it right away. 5 yrs later my MD rotated me between .6 and .4 and I did that for a yr and now she's wanting me to take the .4 full time. I agree- everyone says I have great skin- I think it's gebnetics tho' Polish/german both sides and my folks still lokk 50 and they are in their 70's F 52 10 years
1/26/2009
 5  Had a total hysterectomy I don't believe I have had any negative side effects. I was told I would gain weight after my hysterectomy, and I am heavier then before the surgery and taking Premarin. However, I have been able to lose weight by following Jenny Craig, so I don't believe the weight gain is from either. At age 40, I had a total hysterectomy (both ovaries and uterus)due to Endometreosis. After surgery, I was immediately given a hormone injection, then started taking Premarin. I often get compliments on my great skin and most think I am at least 10-yrs. younger then my 57 years. I do not have a history of breast cancer in my family, and watching my Mother develop a hump on her back by not taking any HRT after her menapause, I have made the concious decision to stay on Premarin 0.625 and have a great quality of life, unlike some of my friends who are scared to death to use it and suffering. In the end, it is a personal decision, everyone's bodies react differently to meds, and based on each individual's family history and life choice. One more plus, I have same libido as prior to surgery/Premarin and experience no vaginal dryness, so no need for vaginal creams, gels, etc. F 57 18 years
1/21/2009
 4  Full Hysterectomy None I can directly blame on this drug. Did have weight gain but this was most likely due to inactivity after operation. My libido is fantastic and I'm looking good for my age. Enforced Hysterectomy at 39. Been taking 1.25mg for 10 years. MY SANITY SAVER. My doctor wants to take me off it due to high blood pressure and the length of time taking premarin I am fighting to stay on premarin. F 49 10 years
1/20/2009
 1  total hysterectomy Pain everywhere. in knees, legs,hips restless leg syn I was put on premarin following hysterectomy just to make up the oestragen and to offset menopausal symptoms after op. I never experienced hot flushes or anything like that but when the scare came in about breast cancer my doctor took me off premarin 18 mths to 2 years ago having taken it for 11 years. I felt absolutely terrible, anxious and nervous all the time, not wanting to go out. So he put me back on it and now I find I have breast cancer. Surgeon reckons Ive had it 18mths or so and the tumor was very oestragen receptive. I did not realise this medicine was made from mares urine and doubt I would have taken it if I had known. But the way of the internet enables me to look things up now. I didn't connect the joint pain with the premarin but now I am off it I have realised it is not so bad. I've been off it three months now and have started hot flushes, but have to get rid of the cancer so have no option. F 57 13 years
1/9/2009
 4  lichen sclerosis weight gain (?), breast tenderness premarin HAS helped my lichen sclerosis although i don't like the idea of being on it long-term. F 34 10 months
12/31/2008
 3  oopherectomy Breast tenderness , heart palpitations , I choose premarin over estradiol . after my sergury I was put on premarin 1.25 .I did get some side effects at first. sore breast, leg cramps , then I heard all the bad side effects premarin will cause .so I got nervous I asked my doc to put me on a bio-identical hormone .I was put on estradiol in fear I would get breast cancer or something from premarin. After taking estradiol for 6 months now I have aged at least 5 years. my skin is loosing its elactisaty my hair is thinning and I still got the side effects as I did when I was on premarin . I went back to my doc and i told him that when I was on premarin I at least had energy my skin looked soft and glowy . As for the bad side effects I felt when I was on premarin It was because the dosage needed to be ajusted .Just like with any med. the scary thing is ladys if you only new what goes into 90% of the meds on the market and the side effects and risk taking them, Its scary . even most of the the food we eat is saturated with pestiside F 40 2 days
12/29/2008
 1  menopause , bone health,etc. The #1 Side effect was peripheral edema, which fluid retention in the legs. This is horribly painful. The fluid does not disappear overnight when you stop the drug, it takes months. Additionally, I had extreme anxiety and mood swings. Wow, my health has never been this bad,never. There is no doubt this drug is toxic to my body. F 53 2 days
12/9/2008
 5  hot flashes, night sweats None. Possibly big weightgain but who knows? It's the PROVERA that's the poison; not this. The Womens' Health Initiative used Provera or Prempro. I take this ALONE and have 0% hot flashes. I cannot live without my sleep, period. Raising my grandson. First week of the month I stop. F 64 20 years
12/1/2008
 1  Total hysterectomy Weight gain 30 lbs..mental fogginess, forgetful, depression, joint pain, swelling. Insomnia.. I was put on HRT after total hysterectomy 3 yrs ago. I didn't see any change initially, but started on a patch which my skin couldn't tolerate (rash). I have aged probably 10-15 yrs. My skin looks horrible..have a tire around my abdomen and have blotchy/brown patches everywhere. I never had weight issues, have been very active. Always had a flat stomach (even after birth of twins!) I have recently had a saliva test done, and have found I have adrenal fatigue. My recommendation is to find a doctor that uses bioidentical hormones and get tested ASAP. We are in process of weaning my dosage, will try to repost with update. F 42 3 years
11/29/2008
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 5  Symptons of Menopause None yet. F 54 5 days
11/19/2008
 5  abnormal uterine bleeding none 1 pill for 21 days each month. F 48 3 months
10/25/2008
 2  Hystorectomy chest pain, hair loss, severe joint pain expecially in knees, anxitey, weight gain, blurred vison, headache, and trouble sleeping. I have been on this medication for 7 months now and I just realized what was wrong. I am no longer going to take this medication. Would not recommend this at all.I thought I had injured my knees they hurt me so bad. F 29 7 months
10/21/2008
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 5  Menopause None what so ever. Doctor has me on .3 mg 25 days on, 5 days off. After one and one half month the hot flashes have disappeared and I can now get a full nights sleep. I no longer go from hot sweat to refrigerator with no in between. It was awful. I tried everything under the sun and got fed up. I had hyst. at 40, kept ovaries. The symptoms took 1 1/2 months to fully go away (you have to be patient). Still need the fan on sometimes. Do not need progesterone due to no uterus. Got three month supply through mail in with insurance coverage and costs $30 per month. F 52 45 days
10/12/2008

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