SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Insomnia It works too well. You have to take it in really low doses (50mg max) & take it early. You will sleep for a very long time & it takes a long time for the groggyness to wear off. M 34 2 months
9/28/2005
 3  BiPolar I None for 18 months at 25 mg. Now at 50-100mg major weight gain, less sleep, weird dreams, hair loss, and anger My Doctor lets me take any where from 50mg-100mg depending on my state of mind and how bad I need to sleep. In the last 3 months I have gained 20 pounds and didn't know why because my Topamax is suppose to keep my weight down. I just recently realized it was from my recent increase in my Seroquel. For 18 months i took 12.5 MG or 25MG and had no weight gains, actually had wonderful weight loss. Now I cannot loose weight and I am working out 5 times a week and barely eating. Since I use to be anorexic this is a horrible problem and is completely depressing me. So I am going to the Doctor on Monday. I started taking 25 MG two days ago and I am actually sleeping better than I was on 50-75MG. F 40 2 days
9/28/2005
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 1  Poss. misdiag. of dprssn for bipo 2 After first night of 50mg the next morning I had the worst "charlie horse" in my left calf I've ever had. My RX was for 25mg in a.m. 50mg in p.m. The following morning the pain lessened some but never went away and I was forced to hobble when I walked. After a week of this I call the pharm. and she said that I probably needed to find another med. and then I called the emergency psych. and she told me to take one more the next night and then quit. She emailed my psych. and told him she'd taken me off. He nor his nurse think that the seroquel was the problem and that maybe the "heat" or low potassium was the issue. I asked then shouldn't I get my levels tested. And she said no, just wait a few days and start again. Screw that, I wasn't playing lab rat! I called my m.d.'s nurse & she put in a blood work order for me. All my electrolites ect. were just fine. It's been over a month and I still have a rock solid calf. I limp all the time and it's thrown all the rest o I waited a week after this "new" diagnois'was made to make sure that I really needed it and that I understood all the side effects. I was scared to death of this med. Muscle stiffness was all that my prescrip. made reference to that would even remotely cover what I experienced, until I read of 2 others here that had calf and foot cramps. I knew it was the Seroquel. F 46 7 days
9/28/2005
 5  for bipolar disoder and depression if yuo taking this medicine you might want to take something for the side effects that couse me that i coul not walk or talk or move my hands for at least 1-3hrs it last for it does make me feel bettr and know i can even work and deal with feeling F 17 3 years
9/21/2005
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 5  Psychosis Zombie Like state. Seems somehow to help me reintegrate myself into society. I was in complete withdrawal from people and totally paranoid. Seroquel, was started off light dose and now its 300mg per day. Seems to work and is so beneficial enabling human interactions. Very satisfied. M 52 60 days
9/14/2005
 3  I have Bi-polar ll This medication is probably one of the best on the market. I now sleep,the anxiety is gone, and I don't have the racing thoughts. Before the drug,I could'nt sleep for weeks and wanted to jump off a bldg because of mania. Three complaints addiction,adiction and all the weight gain, it has put a major cramp in my lifestyle and employment. I now avoid my talent agent because of it, I have gained 30lbs in less than 6 months. I have tried to wean off the drug, but it seems that I was worse off than before starting it, my advice it you is not to get on this drug except for as a last resort, if you thought sleep was impossible before the drug, try to live without it, it seems to alter your body chemistry. I have tried to go back to some of my old drugs as an desperate attempt to live without the seroquel and its side affects, but have found that I am actually more sensitive to former drugs now than before taking seroquel, and I am convinced its because of the seroquel. I know some of you have a weight gain complaint and some of you don't after taking the drug, but I'll will tell you this, I am a serious hiker,and am always active. I am not one with a big appetite, my caloric intake most days is probably lower than the average person, and I this drug has somehow managed to keep me gaining, slowly, I might add, only because I am so active, but even so I am still gaining. Tomorrow I have an appointment with my doctor, and I will request to be off the drug. I just started lamictal at a low dose of 25mg, can't wait to see results, hear it is a good well rounded drug for Bi-polar patients. HR F 36 1 days
9/14/2005
 5  Bipolar II with mixed states The down side to this med has been the weight gain. In the three years I have been taking it, I have put on at least 60 pounds. Diet and exercise don't seem to make a dent. It's frustrating as hell. I attempted to scale back my dose, but my mania returned. Oh well, so much for that idea. Seroquel has been a godsend for me. It shuts off the racing thoughts, gives me peaceful sleep, and along with Lamictal and Topamax, has kept my mixed state self stable for three years. I've needed a tweak here and there, but mainly in the Lamictal department to ease my depression. The Seroquel has remained the foundation of my mixed state/mania treatment. F 42 3 years
9/13/2005
 4  sleep aid It just worked perfectly for the problem of getting to sleep. I haven't noticed any side effects except one BIG one, weight gain. I suspected it but did not really confirm in my mind that Seroquel was related to my weight gain until I just read some postings and some of them fit me to the T. I have gained at least 25 lbs in the little over 1 year I have been taking it. Two months ago I started on a big diet and exercise routine. I mean BIG exercise. I hadn't exercised in 2 years and it was a big deal. Well, I only lost 11 lbs and I was STARVING myself and working out 4 times per week. It was just killing me! You know, you get a little frustrated when you're killing yourself on a grueling routine and get NOWHERE. So, Seroquel works GREAT for knocking me out BUT gaining all of this weight practically makes me want to sleep! (Run and hide.) I've decided to go off Seroquel (100mg)a night and try to just take Lunesta and Benadryl to sleep. I really hope it works because I just M 47 1 years
9/13/2005
 1  Bipolar Disorder/Manic Episode I've been taking Lamictal (as a mood stabilizer) + Lexapro (as an antidepressant). When prolonged stress recently triggered a manic episode, the doctor told me to stop the Lexapro; he also gave me a SamplePak of Seroquel (100mg) with instructions to take 1 that PM & 1 the next AM, which he warned "might make [me] a little too drowsy during the day" but would help to curb the manic symptoms. As it turned out, the 1st tablet put me to sleep for 24 hours straight. I woke up unable to talk without slurring incoherently; when I finally got out of bed (after 36 hours), I was dizzy/shaky with cottonmouth, dyspepsia & diarrhea)…So the doctor told me to try just 1/2 pill that PM: Within 30 minutes, I was out for 12+ hours w/subsequent unsteadiness, cottonmouth + ongoing gastrointestinal upsets. My 2nd 1/2-tablet PM dose caused an URGENT mid-night call of nature; I fell flat on my face enroute to the stairs -- which I negotiated 1 step at a time, hands braced against each This was my WORST drug experience ever -- including OTC, Prescription, Recreational, any or all of the above! In short: If you want to quel your mania by taking 1 tiny tablet that will knock you out, knock you over, almost give you & your loved one(s) a heart attack & then let you wake up in a puddle of shit, Seroquel might could be your drug of choice!* Oh, & did I mention the WIERD DREAMS? *[Personally, I have chosen to quell MY mania by venting herein...& after only 2 more days + 2 doses of Pepto-Bismol & 1 of Immodium, I actually was able to complete this rant without a single enforced potty break] F 47 3 days
9/8/2005
 1  postictal psychosis, psychosis NOS Paranoia, sever depression, slept all day and night, heart jumped out of my chest right after taking the drug. Inability to deal with everyday life events. Abnormal dreams. 400mg/115lbs. Diagnosed with posticatal psychosis , psychosis NOS , or bi-bolar at the age of 48. Attempted suicide after 3 months, advised doctors of depression induced by seroquel. They wanted to add another drug... said no.. Attempted suicide while on zyprexa 4 months earlier. Have any of you read MAD IN AMERICA BY ROBERT WHITAKER....... F 49 4 months
9/5/2005
 3  Bi-Polar & Mood Stabalizer Weight gain of 75 lbs in 3 years, Extreme fatigue during work, Hard to get up in the morning, Feel like I have a hangover, Can't sleep without it now If I am having a panic attack or my anxiety is overwhelming, I like the fact that I can "pop a Seroquel" and I'll be calmed down. But there are so many negative side effects of taking this drug that I think I was doing much better without it. I went from weighing 140 lbs to now weighing 215 lbs. I feel I am somewhat "addicted" to it and fear I will have trouble getting off of it. F 30 3 years
9/4/2005
 1  Major depression psychotic episodes Weight gain 40lbs, restless leg syndrome, lethargy, trouble focusing - eyes and brain. I am currently trying to get off this medication as the side effects (particularly the weight gain) counteract any benefits the drug may have. Weight gained is in fat and not muscle - no matter what you do. I have always had very low body fat and a hard body - until seroquel and it depresses me no end. Would rather be on the edge than fat. I also worry that I have become dependant on the drug and am going to have major problems flicking it - I tried to go cold turkey and didn't sleep more than an hour for a week, so am back on and trying to taper off. M 41 1.5 years
9/4/2005
 3  Insomnia, possible bipolar Muscular contractions, sleepiness (obviously), originally prescribed 200 mg but could not function the next day at work. Reduced my dosage to 25 mg. Still experience sleepiness throughout the day. Feel somewhat disconnected. Everything takes on a surreal feeling the following morning until about Noon. I started taking this with Effexor XR. I noticed extreme sweating, which I believed is associated with the Effexor. I notice that I don't necessarily have muscle twitching per se, but my muscles tend to constantly be flexed. I workout 4 days a week and have a pretty strong nutrition plan in place, so I'm hoping I can avoid the possibly of diabetes. I have noticed that while working out, the constant tension in my muscles actually seems to be a workout aid. I feel a bigger M 25 7 days
8/23/2005
 4  bipolar type II very little i think these reviews are untrue in some regards i would not be surprised if the pharmaceutical companies write half of these evaluations M 18
8/22/2005
 1  Cymbalta Muscle twitching throughout the night and during the day. This greatly effected my sleep and made me very nervous. F 25 3 days
8/18/2005
 3  Bipolar II Sleepiness, but I take it to help me sleep, so that's fine. A little bit of restless leg feeling if I try to stay awake, but nothing serious. The biggest problem is it gives me the munchies, so I've gained quite a bit of weight--about 20 pounds in a year and a half. F 42 1.5 years
8/12/2005
 5  sleep You must be able to have the time for at least 7 hours of good solid sleep. 25 mg. is best for me at 5'6 F 47 2 months
8/9/2005
 1  Bi polar Weight Gain...extreme zombiness ...anger..dry mouth... psychotic actions that i never had before I would not take this medicine again if my life depended on it, it made me very agitated and angry and i literally would snap and not remember anything that i said or done, i havent seen anyone who has had this kinda side effect but really would like to talk to someone who has...i went to jail because the medicine made me attack someone and i didnt even remember it!!!! F 30 3 weeks
8/2/2005
 5  Bipolar 1 w/ pychosis A slight hangover in the morning and some weight gain. it helps in alot of ways. with my depression and with my hatefull actions. makes me mellow! M 50 4 months
8/1/2005
 3  schizo-effective I was taking mega doses (up to 2 grams a day) Severe dizziness, hypotension, some panicky feelings from side effects. restless legs. Very large amount of hair loss. Feel frozen, just a part of a machine. It helped me controll the anger that comes from being helpless against hallucinations;voices telling me bad things, i.e. F 55 4 days
7/30/2005
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