SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Psychosis Stuffy nose, sinus-like. Emotional block. Mental block. Stiffness. Sleep forever. Slows down thought processes. Very dumbening. Erases inspiration. Indiscriminate effects, it blocks both psychotic and normal thoughts alike. It has a chemical holocaust effect, and totally obliterates the mind. F 27 11 days
6/30/2007
 3  Psychosis Stuffy nose, sinus-like. Emotional block. Mental block. Stiffness. Sleep forever. Slows down thought processes. Very dumbening. Erases inspiration. Indiscriminate effects, it blocks both psychotic and normal thoughts alike. It has a chemical holocaust effect, and totally obliterates the mind. F 27 11 days
6/30/2007
 3  Psychosis Stuffy nose, sinus-like. Emotional block. Mental block. Stiffness. Sleep forever. Slows down thought processes. Very dumbening. Erases inspiration. Indiscriminate effects, it blocks both psychotic and normal thoughts alike. It has a chemical holocaust effect, and totally obliterates the mind. F 27 11 days
6/30/2007
 5  Bipolar i speed excessively and want to eat all the time. Seroquel isn't so bad, i sleep like a baby, and i don't think violent thoughts toward people i don't know. If you can master being hungry all the time, then this drug is amazing. Within the first two months of talking seroquel and zyprexa i put on 30 pounds. After struggling to get into my pants, i decided i'd just have to deal with being a little hungry all day long, its a small sacrifice for its benefits. M 21 3 months
6/26/2007
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 1  bipolar - mania The first year on Seroquel I was a total zombie. When I visited family for a holiday dinner I was terrified. How can I possibly stay awake for 4 or 5 hours during the dinner? My energy level went to zero and I felt exhausted after less than an hour out of bed. I went from a muscular (benching 275) 195 pounds to a flabby 245 the first year and let my gym membership lapse. After 5 years the side effects started getting much worse. No erections and crappy orgasms led to a complete loss of interest in sex. I just couldn't stop eating, and would wake up starving in the middle of the night and devoured an entire box of cereal. Of course I was too doped up to go to a restaurant or store, and the cereal for the next morning was the only carb fix around. If chips, cookies or Ice cream were around I cant't imagine how much I would have eaten. 2 weeks after quitting seroquel my glucose was 98, and along with the other symptoms, it appears that I was getting diabetic. Blurred vision imm This drug made my bipolar mania much worse. By engaging in demanding activities in an attempt to feel better and control weight, I was driven into mania but the Seroquel hid the mania. I ended up being hospitalized with a mixed episode after 4 months of mania in 2004. The Seroquel dosage was increased , and I gained 10 pounds in 2 weeks in the hospital. 2 months later, unable to lose the 10 pounds, I became extremely depressed and spent a month planning suicide. The same pattern repeated in 2005 (the cognitive decline side effects of Seroquel prevented me from seeing what happened in 2004) and culminated in a mixed episode where I had a tremendous urge to kill people. Another increase in Seroquel really zonked me out for a few months. The side effects began to worsen rapidly in late 2006 and by early 2007 a horrible event made the decision clear - one of three changes was to discontinue Seroquel immediately - I forget the other 2. Within a week I felt much better and was no lon M 47 5 years
6/26/2007
 5  Anxiety Weight gain (20 pounds) This medicine works! I am no longer a slave to anxiety and panic. Peripheral benefits: seroquel cured my insomnia and, surprisingly, menstrual cramping, which I suffered from for years! F 38 2 years
6/25/2007
 4  bipolar disorder Sedation and confusion 30 - 60 minutes after ingestion, difficulty waking up, extreme confusion after waking up, forgetfulness At first I thought this was a wonder drug - after suffering from a nervous breakdown it made life bearable, 'took the edge off', helped me sleep, helped me get through the day, gave me a lot of mental clarity that I had been missing. I started on 100mg, taking 25 throughout the day as needed, ended up at 600mg (slept faaar too much), came back down to 400mg about 8 weeks ago and have slowly had to come down to 75 - 150mg as needed since then as I was having major problems with sedation, completely oversleeping (missing work etc.), being unable to be woken by others, etc. I have difficulty sleeping without it, and if for some reason I don't take a dose I get hypomanic the next day. I find it helps me heaps, and I haven't had the issues with weight gain that others seem to have had (in fact my weight has dropped drastically), but it's become obvious to me that over time it has completely screwed my memory - I forget words, names of people I have known for years, my own phone number, w F 25 10 months
6/24/2007
 4  Depression/Anxiety/Bipolar/PTSD When I first sought psychiatric care in 2002 I was a wreck. I will tell you that a Psychiatrist has to be advised of all goings on while taking the meds prescribed. I had my doses adjusted and the type of meds changed all based upon the results I experienced. Understand that sometimes I felt terrible only to have the meds stabilize after taking them for a while. Sometimes they stopped providing the desired results my Psychiatrist wanted. I am more stable now and remain so after all the adjustments. I take 100mg of Seroquel for sleep and to help organize my thoughts. It works for me. I agree that Seroquel gives me cravings but this is after about 30 min to an hour so I go to bed within that time frame to keep from eating. I also take 2mg of Gabitril 4 times a day for anxiety, mood swings and headaches. Twice a day I take 30mg of Cymbalta for depression and 200mg of Provigil twice a day for wakefulness. A .5mg Klonopin wafer 4 times a day helps to suppress my anxiety. I praise my Psychia At the direction of my Psychiatrist I went off of the Seroquel and tried lower levels than 100mg. With no Seroquel I could not fall asleep and I would lay in bed with all kind of thoughts racing through my head. With less than 100mg those symptoms went away but I would wake up and go back to sleep through out the night. It seems that 100mg is the magic number for me. M 58 5 years
6/24/2007
 2  BIPOLAR/PTSD SWEATING, STANDING IN FRONT OF FRIDGE AT 5AM FORCING CARBS INTO MY MOUTH UNCONTROLLABLY, ALMOST BLACKED OUT TWICE AND FAINTED AFTER A SWEATING SPELL, LETHARGY, ADDICTION, HORRIBLE WITHDRAWLS, HEAD ACHES, BODY TREMORS, MESSED UP JUMBLED SPEECH THIS MEDICATION IS WORSE THEN HEROIN. NOT ONLY DO DOCTORS TRY TO FORCE IT ON PATIENTS KNOWING HOW EXPENSIVE IT IS BUT THEY ALSO DO NOT TELL YOU IF YOU TAKE IT FOR OVER 2 YEARS YOU MAY HAVE TO TAKE IT FOREVER!!! THEY ALSO DO NOT TELL YOU IT CAUSES SLURRED SPEECH EVENTUALLY...I HAD TO FIND OUT ON MY OWN. AFTER MY WORDS WERE DIFFERENT THEN MY THOUGHTS. IT ALSO HAS A HORRIBLE WITHDRAWL THAT IS SIMILAR TO THE SWEATING ONE WOULD EXPIERENCE WHEN THEY COME OFF OF HEROIN. THIS IS TERRIBLE. I WOULD NOT RECCOMEND TAKING THIS EVER!!!! IT WILL ALSO MAKE YOU GAIN WEIGHT LIKE NO OTHER DRUG AROUND. I WOULD RECCOMEND THIS FOR ANOREXIC PATIENTS. BUT ANYONE WHO IS THINKING ABOUT TAKING THIS MIGHT AS WELL SMOKE A JOINT FOR YOUR DEPRESSION/MANIA, IT WORKS BETTER. F 26 3 years
6/21/2007
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 1  depression A.R.D.S. doctor told my husband I had a 60% chance of living seroquel caused a lung infection then blood clots form.....next went into surgery , heart stopped 3 times they broke a rib doing cpr.,,,,,,,then i had a stroke AGH! F 48 60 days
6/21/2007
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 4  insomnia I black out entirely. I don't remember anything that happens when I take it, though my roommate says I am quite conversational and friendly. I do remember feeling very happy and content while I am "tripping." I sleep incredibly well after I have taken Seroquel. I only take Seroquel about once a week when I can afford to really black out. I would never take it if I were alone. It makes me giggly and happy, but also very sensitive to loud noises, criticism, and worry. F 24 3 times
6/19/2007
 3   The range of effectiveness of this drug is VERY wide and depends on the individual. Some can sleep with 25 mg. I started out at 600 and am now weaning off it because of weight gain. Have gained at least 25 pounds over the last year. Experienced the stuffy nose at (300-600 mg. No longer experience it at 25-50 mg. Physical energy has been low and I have had little motivation to exercise. DEFinite increase in appetite. Otherwise, the drug has been effective in terms of lowering anxiety levels and tempering mood swings and I can understand choosing to take it. F 42 1 years
6/18/2007
 3  Bipolar Disorder II F 25 8 months
6/18/2007
 4  PTSD and unable to stay asleep I have been on 25 mg once a day at bed time for 5 years. About 20 minutes after taking it I need chocolate or anything sweet. I have been known to eat a 12 pack of reeses peanut butter cups in about 1/2 hour. If there has ever been any weight gain it's because of that and not the drug. I also feel slightly groggy in the morning but it passes after a cup of coffie. The drug has been a lifesaver when it comes to a full nights sleep. I also have been functioning amazingly well, (top 2% in sales in my company) and am quite happy on a daily basis when before I had a ton of anxiety and sadness. My big worry is that I have been taking it for so long. I feel like I need to go off it just to cleanse my body but Then I won't sleep. All in all I love it and am trying to get my mom who has insomnia to take it. F 48 5 days
6/17/2007
 3  manic\depressive - losing sleep I've been diagnosed w/ OCD since I was 14. A couple of years ago this diagnosis was changed to bipolar as I was having depressive and manic episodes, sometimes getting only 3-4 hrs of sleep a night for about a month- racing thoughts. Well, my doc put me on zyprexa and that helped but I gained about 30lbs. Then I switched to seroquel and started working out and I got my weight back down. About 8 months later, however, I had to go to the emergency room for dehydration (blood pressure or something dropped 40 pts when I would stand up). dr said it was due to postural hypotension. since then my nights have been bad. 30 minutes after taking it at night I would have trouble w/ shortness of breath and heart racing. Couldnt go to sleep until side effects subsided. I was up to 600mg but have since tapered off to 300mg but now I'm going to try phasing off. It worked for me for a while but these current symptoms are frightening. I dont know if I share similar experiences as other long t Just guage it for yourself M 27 2 years
6/12/2007
 3  Alcohol induced insomnia While it got me to sleep, I slept through 4 job interviews and was unable to get up in the morning. When I do take it I sleep but wake up way too late, sleep through my alarms, and feel like a zombie for the first 3 hours. I also have memory loss, have a hard time remembering who I talked to and what I did that day. Mind eraser. The last 7 months I have taken it seem like a fog. Does not matter if I take 200mg or 50, it knocks me out. Perfect drug if you are a multi millionaire and don't have to work, for the common man who needs to earn a living and get up every morning, forget it. Better off using Sonata, short half life and no hangover. M 38 7 months
6/9/2007
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 4  anxiety i havnt noticed any bad side effects, i have expienced alot of weight gain, 25lbs in just a few months but i also started Depakote 500MG 3x a day at the same time. my doc thinks depakote is the reason for my weight gain. i take 50MG to 100MG at night and it has helped me to sleep like a baby. I love it. F 24 4 months
6/8/2007
 3  Severe Insomnia Fainting, over sedation, hang over the next day, unable to wake up in the morning I was glad to come off of it, but when my friend died, I took it to help me sleep all day, and it worked. I only took 50mg. I used to take 400. That was WAY too much! F 26 1 years
6/7/2007
 1  back pain Stevens Johnson syndrome. Can be fatal reaction causing rash or worse to mucus membranes. My doctor was very insane (hypomanic) My back pain was determined to be delusional. An MD started me on tequin but the pyschiatrist said he would deny the antibiotic if I didn't take 800 mg of this poison, The man should be in jail F 51 5 days
6/6/2007
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 5  Bipolar I Current dose is 400 mg/day. The expected drowsiness and weight gain (in my case 15 pounds, which on a formerly 130-lb, 5'4" frame is a lot of weight). Weight is coming off gradually though. Mild increase in heart rate & drop in blood pressure within first hour after dosing. My psychiatrist reviewed any and all potential side effects with me though so I was prepared, which makes things much more manageable. Also, I spread my dose out into 4 100-mg doses throughout the day, so I don't experience extreme fatigue, dizziness or passing out which was a problem for me when taking 200 mg or more at a time. Overall, great stuff. For me, works better than anything else I've tried (which includes Risperdal, Zyprexa - which brought on extreme heart palpitations - and Lexapro). One thing to remember is that everyone reacts differently to each drug. The only way to truly know if something will work for you is to try it, under the supervision of a good psychiatrist. F 35 6 months
6/3/2007

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