SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1512 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   (Sources: U.S. Centers for Medicare Services, FDA) FDA Approval Date: 2005-10-04

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Dr. said Severe depression, thoughts of suicide F
5/9/2009
 1  Anxiety, Depression, Bi-Polar Get off this medicine!!! I took it for 10 days and it made me feel completely lethargic, lightheaded, dizzy, short-term memory loss, and completely tired. I felt like a complete zombie. I could not concentrate, could not walk straight, I could not even function as a normal human being. I had constant pain in my arms and fingers. Violent mood swings where I was happy one second and crying the next. I have absolutely no sex drive. Tunnel vision. And although it might not be related, I got a urinary tract infection right after starting the med, even though very few men get UTI's. This is the worst drug I have ever taken in my life and I do not know how it was ever approved by the FDA. M 22 10 days
5/6/2009
 2  Insomnia Tachycardia, Tolerance, Occassional Nightmares, Zombie-like feeling, change in body chemestry. I am also fatigued all the time due to getting less and less sleep. I am never get that good drowsy feeling...just fatigue. I have been on this drug for almost a year now. My psyche prescribed it to wean me off of Temazepan which caused me to "crash" after I had built up an incredible tolerance for due to overmedication by my family doctor. I originally took 250mg but successfully weaned down to 150mg within two months. However, efforts to go below 150mg have been largely a failure. In fact, after relatively good sleep in January-March (averaging about 125mg) I have been experiencing some of my worst sleep since crashing in June, 2008. I cannot sleep without taking this drug. I have not had natural sleep in over 15 months now. Even when I am taking the drug, I no longer feel drowsy and it is taking longer for me to get to sleep. Worst of all, I have been slowly been inching up the dosage past 150mg again just to get even minimal sleep. I do not want to go above 150mg again because of the zombie-like affect it has on me (which is bad enough below 150mg) I only average about five hours sleep even with taking the drug. It has been almost three months since I have had a night of 7 hours of sleep or more. My worst fear is that the longer I take this expensive drug, the harder it will be to ever get natural sleep again. Cleary, taking this drug is clearly not sustainable. Anyone with advice on an inexpensive, relatively safe drug that helped them get off Seroquel? M 44 11 months
5/4/2009
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 2  bipolar knocks you out completely, totally destroyed my sex drive, gained some weight initially but leveled out, very sedating, short term memory loss, fuzziness, confusion, trouble concentrating/focusing i take 125 at night plus lithium, topamax and lamictal, but when i have manic spikes take up to 300/day, have taken some during the day and this was the worst. basically, it does fix the mania, but only because i'm a drooling idiot or asleep. i cannot function at all taking this during the day. i would stop taking this right away except it seems to be the only thing between me and the edge. really hate this. F 23 2 years
5/4/2009
 1  Bi Polar 2 I took this medication on a Friday night and proceeded to sleep for 12.5 hours solid. I woke up for 2 hours, and ate everything in sight. I then was so exhausted and dopey that I took a 5 hour nap. I woke up, feeling like my limbs were encased in concrete. I couldn't walk straight or talk clearly. I only took this medication one night at 50mg. I will never take it again. F 21 1 days
5/3/2009
 1  for sleeping i just took it for one night.... I was in the hospital for diabetes and a blood infection and had not slept good for months... they gave me 100 mgs around 9:00 pm and then another 50 mgs around two ol clock in the morning when i given the 100 mgs i went to sleep and slept for about four and a half hours then they gave me 50 more mgs and i felt extrememly wierd!!! I felt like i caould do any thing i wanted and i would have no consquences. i felt like a super hero or something. I had a pic line in my arm and still had a blood infection but i decide that i was going home at about two thirty that morning. So, i stole my moms keys out of her purse un-hooked my iv and left the hospital... Just to make the story shorter i just tell youu what the outcome was i ended up having a head on collision and totaled the car. I had to be cut out of the car and when i woke up i couldn'tmove. I was rushed to Baptist hospital and the feeling came back into my body. I was then put back into the hospital and i was never given that medication again. F 21 1 days
4/30/2009
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 5  Bipolar/Anxiety/depression Groggy for the first couple of hours in the morning, tons of energy in the afternoon (thats good!)Usually knocks me out 20mins after taking it at bedtime. Also taking Ativan when needed for anxiety attacks. I have been on Seroquel for 3 weeks, this medicine has been a life saver for me! I started out on just 25 mg a night before bed, then moved up to 50 mg's. I have actually LOST weight, 5 lbs so far (I put on 15 when my depressive episode returned). For so long I thought Dr's just didnt understand what I was going through, they continued to try me on different anti depressants, all of which made me more anxious and freaked out, to the point I wanted to hurt myself and others! Finally with my Therapist and new Dr, came to my Bipolar diagnosis. Seroquel has helped me want to be productive and actually LEAVE my house again, it has mellowed out my severe mood swings, its helped with my anxiety attacks, but we are still working on that. Im not saying its for everyone, but for a person like me who kept getting the typical depression diagnosis over and over again, I cant say enough good things!!! F 33 3 weeks
4/28/2009
 4  Major depression (debilitating) Initially placed on 600 mg. I gained 50 lbs in 3 months but the gain was mostly water (edema). I was swelled up. After reducing the dose to 100 mg. I dropped 35 lbs in one month and now am 10 lbs. lighter than when I started. I have some nasal congestion and (infrequent) restless legs (but exercise helps a lot with that) and am foggy for the first 3 hours in the morning. I also take 180 mg. Cymbalta. Those of you who are experiencing drastic weight gain should consider the possibility that it's mostly fluid retention (edema) and talk to your doctor about reducing your dosage. At 100 mg. I am getting about 75% of the benefits I was getting at 600 mg. but without the weight gain. M 46 5 years
4/26/2009
 1  bi-polar/depression At 100mg Restless legs and some body twitches. Can not sleep, It will make me drowsy but just as i fall asleep I will suddenly wake up wide awake. The insomnia is making me suicidal. Also I have developed cataracts at age42 and think it is causing sun sensitivity and poor body temperature control in the heat. In addition after reading some of these post my joint and neck pain might be from this drug Initially it was great and really did help with my depression but after 6months these side effects are killing me. M 41 6 months
4/24/2009
 4  insomnia/depression/anxiety I take seroquel mainly for insomnia, I only take 25mg per night and that works great for me. I take 75mg of effexor per day too, in combination with 1.5 mg of clonazepam per day I am a far better person now. I am happy go lucky getting my sleep, not suffering with anxiety and am able to deal better with my life. You can get a little groggy in the morning, just make sure you leave 1o hrs aside for sleeping, this covers the hour you feel groggy in the morning. F 42 90 days
4/22/2009
 4  BP,Rage,Depression,Bizarre thoughts A bit sleepy during the first month. Now taking 50mg morning, 50mg night. Started with 25, and went up from there until I felt good. Also take 300mg 5-HTP, 900mg St.John's Wort, 20mg Lithium Orotate. Seems to be a great, side-effect free cocktail. Great sleep, great dreams, much calmer and happier. Still enjoy life, but not worried about freaking out. Have been taking all the other things for about 2 years, but still needed something to "take the edge off" and Seroquel seems to be the answer. F 47 2 months
4/22/2009
 3  Bipolar disorder Constant headaches. It is awesome at making one sleepy M 39 1 weeks
4/22/2009
 2  depression, headaches, ocd, some bp the shankiness in the legs ruin everything. weight good wich is good for me. drowsy alot. i duno if its working yet. i switched from resperidol to seroquel. im feeling terrible. can you get bad withdrawls even though from switching drugs. im also for depakote for headaches n irritation with neruontin and cogentin wich doesnt help with gettin rid of the restless leg. i havent felt good in 3 years. whut shoulod i do. these meds dont do nything. im tired of bein patient M 21 3 days
4/22/2009
 1  minor sleep disturbances Severe pain in my chest, thoughts of suicide, wanted to kill myself, extremely depressed, extremely tired, memory problems, basically impossible to function. I now know Seroquel is not FDA-approved as a sleep aid but that's what my doctor, Dr. Andrew Sarka, gave me it. It made me really tired, but the other horrible side effects were not worth it. I came really close to killing myself.
4/22/2009
 1  Anxiety Bi-Polar type one symptoms; insomnia. M 27 2 months
4/21/2009
 1  CRONIC INSOMNIA DR.STARTED ME @ 800MG NIGHTLY, OH! I SLEPT BUT COULD NOT WAKE UP FROM FOGGINESS, SLURED SPEECH, WAY BAD COTTON MOUTH, NITEMARES 80lb.GAIN IN 7-8mo. INVOLENTARY TONGE & LEG MOVEMENT, SOILED BED & A HEART ATTACK IN MY SLEEP, COULD'NT WALK 200ft. WITHOUT PROFUSE SWEATING, & PAIN. FOREVER AFTER THIS 'LOVE CANAL' OF DRUGS.... MY LIFE AS I KNEW WAS OVER, IN 02'-03', SEROQUEL DID ME IN, NOW THE LAWSUITS ON TV, NOT BACK THEN. KNEES WENT, BACK PAIN BECAME CRONIC, DISK DEGENERATION FROM WEIGHT GAIN, WEENED OFF AFTER ONE YEAR OF LIFE CHANGING HELL, MEMMORY LOSS, ASTRA-VENZA? KNEW FROM 1999 IT WAS RISKY & DEADLY BUT @ 32 BILLION DOLLARS IN SALES ON JUST THEIR SEROQUEL DRUG ALONE FIRST 2-3 yrs., WHO CARES? RIGHT 'ASTRA-VENZA' YOU ARE A VERY VERY BAD & RICH COMPANY, WE ARE SORRY IT TOOK 80 MILLION? A BILLION? TO PRODUCE OR MORE? BUT AH! THE REWARDS, I KNOW GOD SAID WE ARE ALL CREATED EQUAL, OUR SEROQUEL DOSAGE WAS NOT! NOT BACK WHEN WE DID NOT KNOW WHAT 'ASTRA-VENZA' KNEW..... M 56 300 days
4/21/2009
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 4  to control bi-polar upswing Normally I take 50mg, but when the daylight increases, I go through a tremendous high. In March '09, I increased it 25mg at a time 'til I got to 175mg! I am down to 150, but recognize that I am still in a danger zone so haven't reduced it any further yet. I can't take more than 50mg at a time because I get leg tremors when in bed. I've been stretching out taking the doses starting in the early evening. I am wondering if I took them throughout the day (morning noon and night), if would help curb the eating binges I seem to go through at night. I am not sure if my inability to focus is because of the Seroquel or because of the mania of the upswing. I suspect the latter. At night, I take Seroquel, 300mg gabapentin (Neuronton, for mood stabilizer) and for depression, 75mg Effexor XR (because of its cost, sometimes venaflexine, the generic, a pill that has to be split and taken a.m. and p.m. because of the "half life"). In the morning, I take 300mg lamotrogine (FINALLY the generic of Lamictal is available, MUCH less expensive) for mood stabilization. I know how bad my bi-polar upswing can get (I was hospitalized, involuntarily, for more than 2 wks in 3/03), so I realize that I MUST take the Seroquel when weathering one of these episodes. IS there another drug to replace it that doesn't involve weight gain? F 56 6 years
4/20/2009
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 3  bipolar affective pain in right breast, slight cognitive difficulty, some irritability at first, hair looking flat Psychiatrist started me on 50mg per day but I found that too much and even 25mg was too much so am taking 12.5mg at night now and my mental health is good at the moment. Also take 4mg of stelazine and one cap of lithium in morning. Baby doses of everything but the combo seems to be good at present. Don't like being on any drugs but I get in a real mess if I'm depressed. I work full time and I enjoy that. Not getting weight gain on smaller dose and it seems to be keeping me level. F 55 2 months
4/20/2009
 1  Bipolar Disorder 200mg a day. Too tired to function; 12-20hrs sleep each night, still hard to wake up. Listlessness, apathy, confusion. Dear god no more please. M 20 1 months
4/16/2009
 4  Bipolar/ Anxiety Major, weight gain (fast) At first I felt out of it , fuzzy and disconnected from reality, now I sleep well but now have NO dreams (which sucks), Memory problems, but severely increased focus It comes at a price if you are in a fix with moods and manic phases you must sacrifice your weight/looks to feel better,but then of course in turn you feel worse with decreased self esteem. F 22 2 months
4/15/2009

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