SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  depression and bipolar EXTREME weight gain especially in the stomach. High trigylcerides/cholesterol. I loved initially how it got me to sleep and quieted my mind like no other drug out there. However, I did find myself sleepy throughout the day and was difficult to wake unless I got 10 hrs. of sleep. Yes...ten hours. Avoid this like the plague. Do not take unless it is a last resort...like institutionalization. You WILL get fat and your lab results will show how unhealthy you have become. You will crave carbs even in the middle of the night. I gained 30+ lbs. on this drug. F 43 5 years
1/30/2009
 4  bipolar II extreme sleeping within half hour at night taking 300mg. No weight gain. I must, however, eat upon waking to fend off extreme drowsiness. Grogginess all morning. No longer able to do morning workouts as it is now impossible to feel awake & energized. Husband claims I have improved emotionally. Personally cannot notice much other than more calm and less anxious. This pill feels very strong as it truly knocks me out after taking at night. I wonder if I could wake if the house was on fire?!? F 45 6 months
1/29/2009
 3  Depression / Anxiety / Panic attack Dry mouth, very sleepy; hard to keep one eye open, weight gain, munchies... I'm on 50mg so far and seems to make me think less at night and I sleep good with some good dreams too,it kinda puts everything in slow motion and definately calms the nerves and makes you chilled out, so far I like it but I hear it could contribute to type 2 diabetes so watch what you eat because it does give you the munchies late at night.... M 32 3.5 weeks
1/24/2009
 4  Depression, Insomnia, BPD, OCD Weight loss; Crave carbs late pm; muscle spasms in legs after about an hour after taking it; short term memory loss and inability to multi-task like I used to; vivid dreams that mix with reality so I get confused about what I have said to whom; really hard to wake up once taken drug so hopefully no emergency arises; groggy and down in the mornings but not as bad; more headaches/migraines; gassiness; Nasal congestion 90 mins after taking it, so I snore!; low libido and sex is more painful because of the muscle contraction and dryness. Think I am going into early menopause which is unusual in my family. I thought we were having earth quakes the first few times I woke up after a few hours of taking it, by whole body was trembling. Find I am going through alot of pain killers for the headaches and sore legs etc. It helps me sleep soundly which is a god send, plus I am happier than I have been for the last 40 years. I am also mixing it with Lexapro 10mg (in mornings) M 42 2 years
1/23/2009
 2  Insomnia BE CAREFUL WITH THIS DRUG. It is not tested enough -- NOR APPROVED FOR -- Heart palpitations, shortness of breath, rapid heartbeat, couldn't get up in the morning, nightmares. At first, I thought this drug was great because it cured my horrible insomnia with Effexor. But then, all those odd side effects and fatigue happened, so I stopped using it. F 41 7 days
1/23/2009
 2  insomnia weight gain,dry mouth,morning hangover,trouble falling asleep,having to increase the dose after awhile. i started the med at 25mg,and slowly inched my way up to 300 mg. I stayed there for a year,finally couldnt take the morning hangovers,soo got it lowered back down to 100mg,but I found that I couldnt sleep without taking atarax along with the seroquel. At 300 mg i had excesive munchies,and dry mouth and eyes. At 100 mg the only thing is that I cant sleep. soo anyone out there thinking of raising the dose to 300 mg or more,DONT!! F 29 2 years
1/22/2009
 5  Panic Disorder Extreme sleepiness. I have been on seroquel for about 3 years now. It helps me fall asleep. If I am having a nighttime panic attack i take a little bit of a higher dose and I am able to sleep through the attack. At first it made me groggy the next day- but after time that side effect passes. i wake up just fine now. My husband says that it makes me "blah" all day- i don't feel that way though. I am happy with seroquel- and people say that it causes weight gain but i have not gained any weight. F 29 3 years
1/19/2009
 2  bipolar disorder I feel like my brain has turned to mush. My short term memory is majorly messed up, and I have trouble thinking clearly. I also had some extremely vivid violent dreams and a lot of breast pain. Oh, and menstrual problems. I have wayyyy too much to say about Seroquel, so I wrote a long review of it on Epinions today: http://www99.epinions.com/review/Seroquel_25mg/content_457985199748 If that link doesn't work, go to www.epinions.com and look under username Sunnyglitter. F 26 2 months
1/16/2009
 1  as an adjunct for major depression Since I was also taking other meds it is difficult to determine the effects from seroquel alone. I think this drug is over prescribed in treating depression and insomnia. When I first starting taking seroquel it was at 50mg, it was sedating and while it may have helped with depression it made me feel mentally fuzzy. The drug was titrated up to 150mg from 50 to 100, 125 then 150. At 150mg it seemed to cause some insomnia but it is difficult to know for sure. I have been titrating down 25 mg every 4-5 days and have not experienced any withdrawal symptoms. I have only been taking the drug for about 1.5 months. I don't like this drug because of the potential side effects shakiness (which I do experience), diabetes, tardive dyskinesia, and others.I also experienced a few nights where I would awaken with cold sweats. If you are stopping the drug and have been taking it for a long time make sure you discuss a tapering plan with your doctor. Even if you have been taking it for a short time you should discuss your withdrawal plan with your doc. My doc knew of my dislike of this drug and gave me several options but it was his opinion that this drug would get M 50 1.5 months
1/16/2009
 5  bipolar mania weight gain, constipation, some hair loss, increased libido Thanks to Seroquel I can sleep again like a normal person, which in itself prevents any mania sympstoms from escalating into psychosis. It gives me the munchies after 1-2 hours of taking it so I have gained some weight, however it is something that can be controlled with exercise and a diet free from junk food; the same applies to the constipation. I think the 'munchies' are worse with higher doses so it is important for the doctor to give the lowest effective dose. I am taking 75mg before bedtime and I am happy. I can still think clearly and I am not as irritable as before. For people experiencing severe side effects I believe that lowering the dosage can help. F 27 2 months
1/14/2009
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 4  PTSD/BPD Dangerously low blood pressure (70/40), severe tachycardia (up to 150 bpm even while lying down). Severe gastrointestinal problems, namely severe constipation, which required additional medications. It basically shut my bowels down. Severe sedation; often overslept and was late for work. Would fall unconscious after taking the drug. Could not be woke up after taking the drug. Slurring of speech, amnesia, blackouts, short term memory loss, fatigue; some weight gain, but I fought this off with a rigid diet and a highly disciplined workout regimen. Some binge eating (which I didn't always remember). Difficulty concentrating. It was a huge improvement over the crap they had me on. At first it helped me. I was having severe PTSD symptoms and Seroquel knocked me out and helped me sleep, eliminated recurring nightmares, made the anxiety tolerable, and reduced the disassociation; for awhile, Seroquel was a life saver. I was taking up to 450mg. Then, it became a nightmare. The racing heart was terrifying. ANd one night my heart stopped for a couple minutes. No pulse. Then my blood pressure began to crash regularly. My internist told me I had to reduce my Seroquel or it would kill me. Since then (summer 2006) I have been gradually cutting it back. Next, I was diagnosed with tachycardia, after having severe shortness of breath and landing in the ER twice because I could not breath. Now I take a beta blocker to control my heart rate. The cardiologist says there is no medical reason for the tachycardia. The beta blocker has done more for my anxiety and PTSD symptomps (particularly the adrenalin rush, flight or figh F 33 4 years
1/14/2009
 2  Biupolar, Insomnia, Schizophrenia Major hair loss, major weight gain, excessive sleep, groggy, short term memory problems I have been on 600mg of Seroquel for about 4 years. At first it was wonderful, it helped me sleep helped with my mood swings and somewhat with my delusions. After about 6 months on the medicine I started noticing that I was losing and and have now lost atleast halr of my hair, going from very thick hair to very thin. I also sleep for atleast 12 hours a day unless woken up, and when I am woken I feel like crap for the rest of the day. I have gained in excess of 60 lbs asnd my weight fluxuates quite a bit. I would not suggest using in this medicine in high doses. I am currently trying to find someone to change my medication. F 26 4 years
1/14/2009
 5  Bipolar Dry Mouth, restless legs at night, vivid dreams, tachycardia, morning grogginess, trouble concentrating in the morning. I started with 25mg/day, but I am now at 300mg/day. This is my main form of medication, and I am glad that it is. It is wonderful compared to other Bipolar meds because the side effects aren't as bad. Also, this medication helps me to sleep, which helps with managing a potential manic or depressive episode due to a lack of sleep. I have gained some weight, but I no longer have a "huge" appetite as I did when I first started taking this medication. I recently started having tachycardia which lasts for a few hours after taking it, so I will be talking with my doc about this. Overall, this medication has saved my life. F 23 6 months
1/11/2009
 4  Bipolar/Impluse Control Disorder EXTREME grogginess, weight gain. However, it significantly slowed down my racing thoughts. But my biggest positive is that it gives me a quick "pause" to think before I act violently which I had so much trouble doing before I started taking it. When I first took Seroquel 4 years ago in the hospital, it nearly knocked me unconscious to the floor. I was taking 200mg at bedtime. I couldn't keep my head up. Usually happens an hour after taking it. The side effect feels as if my brain has a brick on top of it, and no matter how hard I TRY to think positively, there is a negative fog that clouds every thought I have. Usually all of this goes away after 2-3 hours, which is why I can only take it before bedtime. Recently, I relapsed and ended up back in the hospital because I stopped taking my meds. I now take smaller 50mg doses of Seroquel at morning and night. I do notice that the negative side-effect is not as severe. M 24 4 years
1/11/2009
 4  insomnia dry mouth i took 100mg right before bed and i fell asleep and didnt wake up for 16 hours. M 18 5 days
1/10/2009
 5  Bipolar I, mania Not every night, but occasionally I get dry mouth, lack of coordination, very rarely a few minutes of rapid heartbeat. I used to get terrible nightmares, but adding Ativan at bedtime stopped that. This drug has been a lifeline for me. It is the only thing that has truly helped my mania. Yes, there are side effects, but they are a small price to pay for having my sanity back. Seroquel does tend to wear off rather quickly, so I'm thinking of trying the XR version to get better all-day coverage. F 46 2 years
1/7/2009
 1  Bipolar Disorder RLS, dry eye, dry mouth, severe weight gain, severe grogginess, rapid decline in vision This medication makes me eat everything in the house! I have gained 80 lbs on it over the years. If I go into a manic and stop taking it, I always lose 20 lbs within 2 weeks. It is supposed to help me sleep, but as the months go by, the sleep is cancelled out by the horrid RLS. I have mentioned all of these effects to my Psyc. and family MD, but neither of them thought it was a big deal and insisted I stay on it. I hate it now. If anyone has a refil for it soon, I suggest to get the manufacturers sheet that comes with the stock med. bottle (NOT the pharmacy print out) and read the effects...it is terrifying. The only reason I still take it is on the off chance of sleeping and when I do not take it, I get very dizzy and get migraines. I have an MD appt. in Feb. I am going to MAKE them take me off of it. BTW, if you are taking this, it is recommended that you get checked every 6 mths for cataracts, triglycerides, and diabetes! With the way this stuff makes you eat, no wonder people get d F 26 7 years
1/5/2009
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 4  Severe Anxiety/ Insomnia I have had some joint pain and have a hard time waking up in the morning. I use to workout in the morning but I cant make it to the gym anymore. I take between 25 and 50 mg, depending on what is going on in my life. I hate to admit that this drug has helped me, but it has helped me sleep and and control my anxiety. I am going to talk to my doctor about going off of this drug, to see what happens, because I just don't like taking drugs. I have started eating a raw foods diet to see how that impacts the way I feel. I did gain a little weight but have been trying to be smart about what I put into myself. M 49 6 months
1/4/2009
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 5  Hormonally driven mood swings Only dry mouth and perhaps a little grogginess in the morning. That goes away very quickly. I am 50, in very good health, very fit and starting to go through my changes. For the past year I have felt out of control. Every month, regardless of whether I get my period I feel out of control, depressed, anxious and unable to get a grip on things. I have tried a number of meds that have made me feel toxic as I am sensitive to medication. I take the lowest dosage of Seroquel and cannot believe the difference. Within 2-3 days I felt like myself again - clear, even, strong and with the ability to sort everything out just fine. I felt jumbled and had a constant knot in my stomach before Seroquel. I hate the fact that I need meds for anything but this has been a Godsend!!! F 50 45 days
1/2/2009
 1  Bipolar disorder Horrible. I have tried lamictal and abilify. I am 61 years old, had OCD since age 12. Have been taking Prozac with complete success for 25 years. Started crying or feeling eurphoric. All of these meds have made me feel like I am no longer me and I hate it. Seroquel does make me sleep great but I'd rather cry all the time and feel like me than this other person. I feel like I am becoming unconscious. I'm off of these now, too, effective tonight. I believe this is my third bipolar episode. Had one 10 years ago. I started taking 2 Prozac instead of only one and it happened. This time my psychiatrist told me to take 2 again for the depression and constant crying, I told him I couldn't and he told me to do it anyway. Big mistake. Prozac is my "get out of jail free" card, and I won't do without it but the seroquel is horrible for me. I only took 25mg last night. I was perscribed 100mg, then he decreased it to 75. I decreased it to 50, then 25, and now zero. Makes me feel unlike myself. F 61 15 days
1/1/2009

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