SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Bipolar Depression I felt like I was on a horse tranquilzer. The first day I took it, I was totally out. I stopped it after that day. F 22 1 days
2/23/2008
 5  Bipolar Wild, vivid dreams, nightmares. Weight gain. After trying just about every other medication for my depression and experiencing either limited relief or horrible side effects, I tried Seroquel and have been very pleased with the results. I cannot comment on the side effects that some mention regarding groginess, etc. as I take pain killers that would mask that symptom/side effect. M 55 2 days
2/19/2008
 1  BIPOLAR MANIA EXTREME WEIGHT GAIN of more than 100 pounds. Unless you have an extreme medical reason that no OTHER DRUG cannot help, do not take SEROQUEL. With this much weight gain you could literally be killing yourself slowly. M 38 3 years
2/19/2008
 2  Anxity,seeing things,hearing things Constipation,crushing chest pains,vivid dreams,zombie like could not function,slow alertness,nothing really matter. I slowly was introduced to 300 mg but the night I took it I thought i was stroking out chest crushing pain my heart felt like it was about to burst right out of my chest. Next night i broke it in half and still was like a zombie.This is an awful medication to be on. I was prescribed this because I had real high anxiety and thoughts of crazy things and seeing things that were not there my doctor said that was because of the prozac. The only thing I did like was the crazy dreams very vivid almost real like. F 43 8 days
2/18/2008
 1  Panic Disorder/Anxiety/Bipolar Excessive sweating, suicidal ideations, crying spells, stoned feeling, anxiety I stopped taking this drug two nights ago and I still cannot stop sweating. It's awful. I sweat when I am sitting, doing nothing, wearing nearly nothing. I can't stop. This drug, along with pretty all the rest of the prescribed medications for these disorders, are nothing but terrifying. Seroquel in itself has 1665 side effects recognized by the FDA. It is also addictive, which is something I was never informed of. This drug did nothing but horrify me, so it absolutely did not help with my panic. It made me suicidal, so it absolutely did not help with depression. I suggest finding another option if you have any kind of nervous disorder. We are patients, not lab rats. F 24 2 weeks
2/12/2008
 1  bi polar/ insomnia problems The very first night I took this it immediately knocked me out. The next morning I literally could not lift my head off of my pillow and I was drooling. I could not get out of the bed to go to the bathroom until noon and then everything was slow. I spent 2 days in the bed behind one of these dangerous little pills. I think this medicine could be very dangerous and when I told mey doctor how this medicine had me " paralyzed" she said she had never heard of anyone having this experience before. F 28 1 days
2/11/2008
 1  insomnia I took it before bedtime and had extreme restlessness and couldn't lay still, was extremely hungry and had to get up to eat, and it took longer to get to sleep than usual. I eventually did get to sleep and woke up groggy. I reduced the dose and had less extreme side effects but it still made my insomnia worse M 40 12 days
2/10/2008
 4  Anxiety; Depression; Mood Swings Drowsiness; dizziness Love the drug; it has made me feel like a normal person again. I take Prozac as well as Seroquel in order to subside some of the violent mood swings one may experience as a side-effect of fluoxetine. Great medication; recomend it highly. M 25 2 months
2/9/2008
 5  INSOMNIA ALITTLE FOGGY IN THE AM BUT NOT TO BAD WORE OFF WITH BREAKFAST AND A CUP OF COFFEE. I ONLY TOOK 12.5 MG AND THIS STUFF REALLY WORKS!!! I HAVE TRIED EVERYTHING TO SLEEP FROM AMBIEN, LUNESTA, XANAX, LIBRIUM AND NOTHING EVER KEPT ME ASLEEP!!! THIS DRUG MAY NOT BE FOR EVERYONE BUT IT WAS THE RIGHT MEDICATION FOR ME!!! MEDICATION WORKS DIFFERENTLY FOR EVERYBODY ...IT MAY BE WHATS RIGHT FOR YOU!!! F 33 3 months
2/8/2008
 4  to correct a tic I developed worst side effect is difficulty in waking up in the morning. Also, I perspire in my feet and groin. Big upside is worth low downside, for me. M 55 4 months
2/5/2008
 1  Bi-polar II DON'T TAKE!!! Anger, agitation, 2-3 hour crying spells like I've never had before. You will turn into someone else. Not cool. Seroquel made me psychotic (ironically), and that's on the lowest dose! Please hear me out as I have a MA in Psych. and I am like you, off the bell-curve with supposed "Bipolar II". I've given this drug 3 chances the last 6 mo., & have not been able to take it. After drowsiness wears off, agitated in bed, angry, have 2-3 hour crying spells, and this last time at 3:30 a.m., had to get out of bed and hit my pillow against the wall because of anger and agitation. This is not like me!! My Bi-polar symptoms are quite different than this. I have never done this before and it happens when I take seroquel. People, please be careful! Be yourselves without taking drugs. Just because we don't conform to the norm in society doesn't mean we are not healthy or that we need fixed. There are no medical tests to prove "mental disorder". Be your creative unique selves w/out thinking you need to be a 9-5 M-F person. I'm done with pcyhiatric meds. Interesting how anti-depressant F 33 1 weeks
2/5/2008
 4  bi-polar/ phychosis weight gain due to cravings already described, really vivid nightmares,does knock me out pretty quickly. I was first diagnosed as bi-polare 16 yrs ago and have been on about every med you can think of. I'm currently taking depakot,sero,klonopin,and,invega. My symptoms have been pretty severe through the years ie, several hospitalizations a number of mania induced legal problems that sort of thing. I think that this med is very powerful effective for me but you should way this against the severity of your own symptoms.I can't see this as being the answer to insomnia, depresion,anxiety It just seems like overkill. M 32 3 months
2/4/2008
 1  Anxiety Very lethargic, cannot function at all, indigestion, uncontrolable movements, if I would close my eyes, I would start 'soaring', blurred vision, fast heartbeat, stomach upsets On the second day of taking it, I had an indigestion in the morning and stomach upsets. I was very lethargic and I would not recommend to begin a treatment with seroquel if you have work the next day. M 22 4 days
2/1/2008
 1  Severe Depression and Anxiety MAJOR WEIGHT GAIN. I wasn't overweight when I started taking Seroquel, and never had been, but it put 100 POUNDS on me within 12-18 months! I'm not kidding. The 100 pound weight gain from Seroquel has been devastating to me. I want to hide in my house so that people won't see me. It has caused me to have GERD (gastro-esophogeal reflux disease) where I've had to have two operations where they've put a camera and a scope down my throat. Acid reflux was causing erosions in my esophagus (all because of the weight gain due to the Seroquel). And then I developed severe sleep apnea, once again due to the horrific weight gain due to the Seroquel. I had two polysomnographies and I would stop breathing 1,000 times a night. I now have to breathe with a CPAP machine forcing air down my airway at night so that I don't stop breathing or have a heart attack. I can barely move now-- getting up and down from bed or a chair and even walking a few steps is very difficult. I can't clip my own toenails or shave my legs or put on my shoes because of the terrible weight gain due to the Seroquel. I live in fear of developing heart disease and diabetes. F 41 2 years
1/31/2008
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 4  Chronic, life-long insomnia I have not experienced the typical side-effects of weight gain or the other effects I've read about. I began with 50 mg dose at night, but I was sleeping 10-12 hours, so I cut the pills in half (12.5 mg) and that did the trick. I thought I had found the "Holy Grail" of sleep aids, since nothing had ever worked before. However, after about six months, the effects seemed to wane slightly. A couple of months ago, I began to have intermitten full-on panic attacks. At first, I thought it was stress from the holidays. But the panic attics continued and grew worse in January, and I began sleeping less. I'm beginning to fear that my body is becoming immune to the drug, and that the effects are changing from a positive sleep aid to a negative anxiety inducer. I mean, even trivial things were starting to just FREAK ME OUT, such as the thought of needing to affix the 2008 stickers to my automobile license plates or refilling my pets' food bowls. I tried going off it a couple of nights, but I flat-out could NOT sleep. I'm giving it a few more days, and then I'm calling the sleep clinic and asking to try something new. I would love to hear from anyone else who has experienced these symptoms. M 45 9 months
1/30/2008
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 2  Bipolar Disorder Nighmares; Erratic, painful, heavy periods; spaced out, hard to concentrate at work; sleeping a lot but tired all day; no sex drive F 39 6 months
1/29/2008
 4  OCD/GAD/Chronic Insomnia/Bi Polar Negatives: Carb craving/weight gain; restless legs syndrome; lack of drive; reduced libido; stuffy nose; reduced after several weeks of treatment. Positives: mood stabilized, anxiety greatly reduced without the use of Benzos, anger control, no nightmares, better quality of sleep, greatly reduced OCD/repetitive thoughts. I have been on Seroquel XR 400mg for about two weeks now and all of the above negative side effects have increased. I will be titrating myself back down to 300mg XR this week since the side effects were less intense with the same degree of positives (the RLS and lack of sex drive in particular). Definitely give this drug time to work, as the side effects do lessen over time after the first few weeks of treatment or dosage change. The weight gain is a problem, but drink a lot of water and excercise regularly and you can at least stop the weight gain. The XR does not give you as large of a rush when you first take it at night, works throughout the day to help with your disorders, and I recommend it over taking multiple doses throughout the day to avoid the up and down feeling. I definitely feel the benfits heavily outweigh the side effects once you are accustomed to how the medication affects you. Everyone around me has noticed how my behavior has greatly improved and I feel human M 33 3 months
1/28/2008
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 2  Insomnia - (am also Bipolar) Very dry mouth, very dry, sore eyes, bad taste in mouth, drowsiness, constipation, hang-over effect, mind fuzziness. I'm very worried about taking this medication after reading the comments here. I for sure do not want more weight gain and these awful side effects. But can anyone tell me what has worked better for insomnia due to anxiety? I took 100 mg of the Seroquel the first night - was way too hung over next day, then 35-50 mg the next 3 nights - 1 of those nights did not sleep well at all. Last night was better but today am quite groggy. I also take Lamotrigne 200 mg and Lithium 900 mg/day. If anyone has gone off the Seroquel, can you write about your experience, and what if anything did you take instead? F 54 4 days
1/26/2008
 5  Bipolar, anxiety sleepiness & weight gain I was taking this several years ago and gained 60 pounds. that was the main vain reason i quit using it. i did lose the weight, though my severe level of anxiety and quick witted anger has taken control of my life. i now take seroquel again 400mg daily along with 3 tranquilizers a day (lorazepam). As i told my doc... living in my brain was like pure hell on a daily basis. At this point, I welcome the lethargic afternoon naps and the dyslexic typing, thank goodness for spellcheck and a very understand loving family. I've already noticed the weight gain again... shooot. but days of normalcy outweigh the extra pants size or two... hell... maybe i'll go up a cup size! lol F 38 1 months
1/24/2008
 3  bipolar, obsessive thoughts weight gain, weight gain, weight GAIN. 40 lbs in 12 mos- and subseqeunt depression because of it! Blurred Vision, dopey "out of it", thinking slowed way down, no mojo, sleeping more, wake up in a fog, DEPENDENCY. How do I describe how seroquel has been both my wonder drug & worst enemy? This was the 1st med prescribed after a yr of rapid cycling mania/depression & the inability to sleep due to racing/obsessive thoughts. The 1st night I took this pill, 25 mg which still knocks me out after a yr I thought I died & went to heaven. Sure I nearly fell into my plate head 1st at the dinner table & my speech was that of a drunk, but SLEEP- precious sleep! This med quells mania & knocks you out cold. Sadly, this med also made me an insatiable cookie monster. Shortly after ingestion, I am literally 'driven' to seek & devour any sweet & cakey thing in my path before rolling over & falling asleep with nuts & chocolate packed in my teeth. This pill has also given me cavities. I have, on occasion woken up @ mid-night & eaten 2 heaping bowls of sugary cereal like a starving, rabid animal & then topped that off w/ a snack cake chaser before tossing my exhausted bloat F 29 1 years
1/22/2008

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