SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  anxiety, insomnia, depression, PTSD None that I note other than being too sleepy if I do not allow a solid 8 hours sleep after taking it. ** No weight gain at all and no increase in appetite.** In fact, since I started eating a diabetic diet 18 months ago, I've lost 30 lbs. Sleep, GLORIOUS Sleep! It definitley has a calming effect for me which has enabled me to reduce my valium intake. (always a good thing!) I do need to make sure I take it by a certain time each evening if I want to be up and at work on time the next morning. F 39 2 years
11/30/2005
 5  Schizoaffective Disorder Used to be really thin-must have gained about 70lbs during the five years I have been on this med. I love how the paranoia, confusion, hallucinations ect. have been successfully blunted, and I can sleep, which is great. But I have been hungry constantly on this med-I am now aggresively trying to lose weight on a diet pill program after trying hard just through excercize and dieting. No matter how much I excercized, and I used to walk upwards to 6 miles a day, I only lost about fifteen pounds. So I was about 179 on my lowest seroquel weight, I should be about 135 considering I am 5'9" and have a petite frame. My triglycerides also have skyrocked-This med seems to have the effect of speeding up the aging process-you get fat, with high cholesteral and you drink ridiculous amounts of coffee to gain your senses again. Nevertheless, this antipsych is better than any of the others I have been on as I don't have the awful akasthasia anymore. F 42 5 years
11/27/2005
 3  Schizophrenia Hair loss (very concerning) moderate weight gain, though less than when using other antipsychotics like Zyprexa. Dry mouth is horrible, at night/morning especially. Muscle spasms at night, which used to be intense and almost intolerable. Taking magnesium supplements helped contain those. Motor skills coordination problems, some days worse than others. Intense hungover feeling every day, takes several hours for this effect to leave each day, which means I sleep for 10 hours +, and am hungover for 4 or 5. Most of each day wasted. Very hard to get up for work, etc. Contains positive and negative symptoms of schizophrenia quite well, but I am getting so distressed by the side effects, I am looking for an alternative to this medication. M 26 4 years
11/26/2005
 5  insomnia/mixed state bi-polar It's made it difficult to lose weight, but I don't think it's made me gain any. Memory is definitely affected. Seroquel saved my life - I didn't sleep for 6 years and was on a slippery slope down the bipolar path. On Seroquel, I sleep like a normal person and no longer have the intense anxiety, anger, or depression that characterized my daily life. Also- if I allow less than 8 hours of sleep on Seroquel, I feel drugged out - but that has forced me to take care of myself and actually schedule enough sleep time. F 35 2 days
11/25/2005
 5  insomnia/mixed state bi-polar It's made it difficult to lose weight, but I don't think it's made me gain any. Memory is definitely affected. Seroquel saved my life - I didn't sleep for 6 years and was on a slippery slope down the bipolar path. On Seroquel, I sleep like a normal person and no longer have the intense anxiety, anger, or depression that characterized my daily life. Also- if I allow less than 8 hours of sleep on Seroquel, I feel drugged out - but that has forced me to take care of myself and actually schedule enough sleep time. F 35 2 years
11/25/2005
 5  bipolar and severe depression increase in appetite and memory loss from when i take my meds until next morning although i have gained some weight i am much more concerned about my mental state i find the meds are definetly improving the mood swings,but i also take lamactil,100mg at night, efexor 150 night and 75 morning, zopiclone 2 7.5 night, proprananol 80mg morning, ciclizine and lorazepam as required and last but not least seroquel 450mg nightly and 100mg morning. I am somewhat concerned about the memory loss. as far as being hungry constant, I am trying to control this myself as i feel the meds can only do so much, the rest is up to me. Ihave suffered bipolar from the age of 13 and have had severe depression on top for 5 years as a result of my sons death. But in my adult life this is the first meds that have eased the swings, suicidal thoughts and given me a full nights sleep,although night terrors are at times a problem.I do find it really does slow up the racing thoughts in the brain enabling me to relax and not worry so much, most of the time anyway. I would really appreciate others F 42 1 years
11/22/2005
 4  BP RAPID CYCLING, insomniam anxiety Short term: Side effects are intense-like hitting a brick wall. Dry mouth, difficulty thinking and talking shortly after dosage but the body gets used it at low dosages in particular. Large dosages will put me to sleep unless I am higher than a kite. Long term use has not had any real side effects except for the traditional weight gain with an anti-psychotic. My immediate world credits this drug for turning me into a relatively sane and functioning individual (BP rapid cycler, anxiety, severe insomnia. It put me to sleep at night (with 200 mg) and awake in the morning since it has a short half life. A small dose in the am of 25 mg kept me mellow but not drugged during the day. IT is increased of times when I crack apart and willing to give up the remainder of my life to the drug=I guess it is a balance. It is tauted as a mood stablizer which I cannot necessarily vouch for given that this is only one drug in my arsenal of 6 RX of a rapid cycler. After over 3 years on this drug, I am trying Zyprexa as a new avenue to gain greater sanity since there seem to be few options left and I still could use a bit more...At this moment, I much prefer Seraquel over Zyprexa in terms of sleep and mental clarity but Zyprexa for mood elevation. F 35 3 years
11/21/2005
 5  Icouldn't sleep prior to Seroquel. I experienced no side effects. Seroquel has been a Godsend. I can sleep all night every night. I wake with very little or no feeling of being hung over. Prior to this med, I couldn't sleep for days, and could only fall asleep by passing out from exhaustion. Then the same horrible experience would occur again and again. I probably have a screwed up suprachiasmatic nucleus. MAN it makes me feel smart to say that. I think I'll say it again. Suprachiasmatic nucleus. WOW! Anyway, kudos to the makers of this med. Can you repay my student loans? M 44 3 years
11/18/2005
 5  Schizophrenia drowsiness at first but subsided after time. I take 600mg at night because I need it to sleep. I was taking 400mg in the pm and 200mg in the am but I was too drowsy at work. So now I take it all at around 6:00pm and have a good nights sleep and wake up refreshed. It has managed my symptoms pretty well...at least better than all the other ap's I have tried. F 33 2 months
11/14/2005
 3  insomnia Weakness and anxiety after dose wore off Seroquel seems to help regulate and induce sleep very well. When I don't take seroquel, I often wake up 10-15 times a night if I'm lucky enough to fall asleep in the first place. I take an extremely low dose since I'm sensitive to medication (12.5 mg). At first, I had no problems with the med. After a couple of weeks on it, I began to feel anxiety and weakness as my dose would wear off. I'm sure my body has become acustomed to the med, so I'm going to try taking a morning and an evening dose. Hopefully this works since it is the only effective sleep med for my insomnia (even benzos don't work very well). M 25 4 weeks
11/9/2005
 1  chronic depression and anxiety I am on Cipralex anti-depressant and my doctor recommended I try Seroquel as an anti-anxiety. I took it for five days and I experienced confusion, loss of focus, couldn't read a thing, dizziness, self paraonia, anxious, and it knocked me out (I fell asleep within 1/2 hour of taking it for 3-4 hours. It made me feel awful. F 44 5 days
11/2/2005
 4  Manic Episode Yes I did gain a few pounds, but nothing that can't be rectified. Also felt a bit dizzy whenever dose was increased Taken as adjunct agent along with Lithium and Tegretol, my mood gradually became stable. I continue to take 300mg at night and 200mg in am and I don't feel sedated. I feel good on it. My doctor feels if am doin so well on it i should stay on it for now anyway. F 28 6 weeks
11/1/2005
 5  Bipolar,insomnia,anxiety drowsiness, dry mouth, agitation This drug is great. It relaxes both my body and mind. I barely gained any weight it and it has completely turned my life around. I have made so many gains since I started taking seroquel. I have a great job and I'm doing better at university, and I am an overall happier person. 2 years
10/25/2005
 4  Chronic Insomnia Very difficult to get up in the morning. Really bizzare, vivid dreams @ 12.5 mg which went away when I increased the dosage to 25 mg. per night. Weight gain - I am sooooo hungary all the time. Recently, I have had problems with severe heartburn/gastric reflux, but I am not sure if this is related. I definitely sleep better, which I am sure is also the reason for my improved mood. I can not sleep without it, but I am not really concerned b/c I have had difficulty sleeping for most of my life. However, I am concerned about the weight gain - I am in the Army, and getting fat can get me into a lot of trouble. F 33 1 months
10/25/2005
 3  bipolar disease EXTRME drowsiness, muscle twitches at night (it seems that as soon as my mind wants to go to sleep, my legs and hands don't,), HORRIBLE nightmares It helped with the auditory hallucinations (hearing voices), but if you are to take this drug take it when you don't need to be awake as is causes severe drowsiness. The muscle twitches were tolerable once my body finally decided to go to bed, but the nighmares were horrific. I at first thought it was "just me" until i saw that other people had vivd dreams and nightmares on this med too. I am also diabeteic (prior to taking drug) and I am interested to see how this affects it. I am currently taking 200mg at night. So although the meds technically worked, the side effects (esp the vivd nightmares and twitches) are plaguing. M 29 5 days
10/20/2005
 5  Psychosis and Mania somnolence, dry mouth, slurred speech, problems with walking correctly/balance. Some difficulty with sleep. Problems with urine retention. Zombie like state. Difficulty concentrating. Seroquel has restored my life to me. I no longer experience mind riveting paranoia. I am much more relaxed. I live in the moment, I do not seem to worry about tomorrow as much as I did before. Overall my life has been restored to me, as I am much more affectionate to family, I have slowed down from mania and feel happier about my self. Please email me if you have any questions. M 52 45 days
10/15/2005
 2  Anxiety/depression Dry mouth (not a big deal), Zombification (not a huge deal), Anger/rage/ lashing out (very big deal) This medication put me in a very dangerous state of mind though not at its peak in my blood, rather in the morning after having taken it multiple times through the prior day. I assess my rage side effect as being some type of withdrawal from Seroquel as opposed to a direct effect of the drug. This happened only this morning and I have yet to speak with my DR. Fortunately, I am writing this from home and not from a prison cell. I would recommend people pay close attention to their moods and self control while getting used to this medication. M 40 1 weeks
10/11/2005
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 2  BiPolar Anxiety and nausea in the morning. Different feelings at different levels. Slept well though. Going off of it is difficult. Insomnia. F 36 4 weeks
10/8/2005
 4  Bi-Polar I started Seroquel along w/ trileptal while inpatient. I'm on half a 25 mg tab in the AM and 50 mg of Seroquel at night. Trileptal 300 mg, twice daily. Terrible nightmares the first few nights and that has stopped. I did feel like a zombie, but I can tell I'm getting used to it. I have been having stomach cramps for an entire day and I'm not sure if it's drug related at all. It feels like it. I've been on other medications that cause me to feel the same way, but again, I'm not certain. No racing thoughts. I can go to bed and relax. My overall mood is better. I feel more organized and have focus to take on a task at a time instead of seeing it all and not doing anything. Overall, much better. F 34 2 weeks
10/6/2005
 3  Insomnia, anxiety and depression Few pounds in weight gain at first but managed to fight them off with Atkins Diet. Sleepiness long after waking up. Dry skin and corns on my baby toe. Slight sexual side-effects. I take 2x25 mg before bedtime. It's a great anxiety and insomnia killer. However, my depression stayed firmly in place. I'm hoping to lift this by adding 150 mg Wellbutrin SR which I now feel (day 11) is increasing the anxiety again. May be this is only a side effect of Wellbutrin which will pass?? Anyone who can shed some light on this: feel free to e-mail me! F 37 5 months
10/1/2005
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