SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1512 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   (Sources: U.S. Centers for Medicare Services, FDA) FDA Approval Date: 2005-10-04

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Severe Depression and Anxiety MAJOR WEIGHT GAIN. I wasn't overweight when I started taking Seroquel, and never had been, but it put 100 POUNDS on me within 12-18 months! I'm not kidding. The 100 pound weight gain from Seroquel has been devastating to me. I want to hide in my house so that people won't see me. It has caused me to have GERD (gastro-esophogeal reflux disease) where I've had to have two operations where they've put a camera and a scope down my throat. Acid reflux was causing erosions in my esophagus (all because of the weight gain due to the Seroquel). And then I developed severe sleep apnea, once again due to the horrific weight gain due to the Seroquel. I had two polysomnographies and I would stop breathing 1,000 times a night. I now have to breathe with a CPAP machine forcing air down my airway at night so that I don't stop breathing or have a heart attack. I can barely move now-- getting up and down from bed or a chair and even walking a few steps is very difficult. I can't clip my own toenails or shave my legs or put on my shoes because of the terrible weight gain due to the Seroquel. I live in fear of developing heart disease and diabetes. F 41 2 years
1/31/2008
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 4  Chronic, life-long insomnia I have not experienced the typical side-effects of weight gain or the other effects I've read about. I began with 50 mg dose at night, but I was sleeping 10-12 hours, so I cut the pills in half (12.5 mg) and that did the trick. I thought I had found the "Holy Grail" of sleep aids, since nothing had ever worked before. However, after about six months, the effects seemed to wane slightly. A couple of months ago, I began to have intermitten full-on panic attacks. At first, I thought it was stress from the holidays. But the panic attics continued and grew worse in January, and I began sleeping less. I'm beginning to fear that my body is becoming immune to the drug, and that the effects are changing from a positive sleep aid to a negative anxiety inducer. I mean, even trivial things were starting to just FREAK ME OUT, such as the thought of needing to affix the 2008 stickers to my automobile license plates or refilling my pets' food bowls. I tried going off it a couple of nights, but I flat-out could NOT sleep. I'm giving it a few more days, and then I'm calling the sleep clinic and asking to try something new. I would love to hear from anyone else who has experienced these symptoms. M 45 9 months
1/30/2008
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 2  Bipolar Disorder Nighmares; Erratic, painful, heavy periods; spaced out, hard to concentrate at work; sleeping a lot but tired all day; no sex drive F 39 6 months
1/29/2008
 4  OCD/GAD/Chronic Insomnia/Bi Polar Negatives: Carb craving/weight gain; restless legs syndrome; lack of drive; reduced libido; stuffy nose; reduced after several weeks of treatment. Positives: mood stabilized, anxiety greatly reduced without the use of Benzos, anger control, no nightmares, better quality of sleep, greatly reduced OCD/repetitive thoughts. I have been on Seroquel XR 400mg for about two weeks now and all of the above negative side effects have increased. I will be titrating myself back down to 300mg XR this week since the side effects were less intense with the same degree of positives (the RLS and lack of sex drive in particular). Definitely give this drug time to work, as the side effects do lessen over time after the first few weeks of treatment or dosage change. The weight gain is a problem, but drink a lot of water and excercise regularly and you can at least stop the weight gain. The XR does not give you as large of a rush when you first take it at night, works throughout the day to help with your disorders, and I recommend it over taking multiple doses throughout the day to avoid the up and down feeling. I definitely feel the benfits heavily outweigh the side effects once you are accustomed to how the medication affects you. Everyone around me has noticed how my behavior has greatly improved and I feel human M 33 3 months
1/28/2008
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 2  Insomnia - (am also Bipolar) Very dry mouth, very dry, sore eyes, bad taste in mouth, drowsiness, constipation, hang-over effect, mind fuzziness. I'm very worried about taking this medication after reading the comments here. I for sure do not want more weight gain and these awful side effects. But can anyone tell me what has worked better for insomnia due to anxiety? I took 100 mg of the Seroquel the first night - was way too hung over next day, then 35-50 mg the next 3 nights - 1 of those nights did not sleep well at all. Last night was better but today am quite groggy. I also take Lamotrigne 200 mg and Lithium 900 mg/day. If anyone has gone off the Seroquel, can you write about your experience, and what if anything did you take instead? F 54 4 days
1/26/2008
 5  Bipolar, anxiety sleepiness & weight gain I was taking this several years ago and gained 60 pounds. that was the main vain reason i quit using it. i did lose the weight, though my severe level of anxiety and quick witted anger has taken control of my life. i now take seroquel again 400mg daily along with 3 tranquilizers a day (lorazepam). As i told my doc... living in my brain was like pure hell on a daily basis. At this point, I welcome the lethargic afternoon naps and the dyslexic typing, thank goodness for spellcheck and a very understand loving family. I've already noticed the weight gain again... shooot. but days of normalcy outweigh the extra pants size or two... hell... maybe i'll go up a cup size! lol F 38 1 months
1/24/2008
 3  bipolar, obsessive thoughts weight gain, weight gain, weight GAIN. 40 lbs in 12 mos- and subseqeunt depression because of it! Blurred Vision, dopey "out of it", thinking slowed way down, no mojo, sleeping more, wake up in a fog, DEPENDENCY. How do I describe how seroquel has been both my wonder drug & worst enemy? This was the 1st med prescribed after a yr of rapid cycling mania/depression & the inability to sleep due to racing/obsessive thoughts. The 1st night I took this pill, 25 mg which still knocks me out after a yr I thought I died & went to heaven. Sure I nearly fell into my plate head 1st at the dinner table & my speech was that of a drunk, but SLEEP- precious sleep! This med quells mania & knocks you out cold. Sadly, this med also made me an insatiable cookie monster. Shortly after ingestion, I am literally 'driven' to seek & devour any sweet & cakey thing in my path before rolling over & falling asleep with nuts & chocolate packed in my teeth. This pill has also given me cavities. I have, on occasion woken up @ mid-night & eaten 2 heaping bowls of sugary cereal like a starving, rabid animal & then topped that off w/ a snack cake chaser before tossing my exhausted bloat F 29 1 years
1/22/2008
 3  DID, PTSD, depresssion, insomnia I gained over 40 pounds on this medication. I have been gaining weight with several anti psychotics for a while. I went from 110 to 230 pounds, then I finally went from 230 to 165 and then my new psychiatrist started me on Seroquel, very slowly. I then gradually went up to 195 and I can not lose it no matter what I try. My Psychiatrist reduced my dose from 800mg to 600 mg at bedtime. I do crave sweet foods late at night. I hate the weight gain but it helps me sleep when I don't take it I just don't sleep at all and become paranoid and suffer horrible child sexual abuse flashbacks. There has got to be a better way to help with PTSD effects rather than a drug that causes horrible weight gain. I used to be an active anorexic and was very thin and this just makes everything so much worse with body image. F 38 2 years
1/21/2008
 5  bi polor and to help me sleep it just makes u really tired and hungry i would fall asleep with food in my mouth F 23 2 years
1/20/2008
 4  Bipolar I Very groggy in the morning and find it hard to get up early. Also, if I am forced to wake up too early, I have "waking dreams" with Seroquel...kind of like hallucinations, but more like a dream (except I know I am awake and what I am seeing is not real). I don't dare drive before 10 am. I take this drug 25mg in the morning and 50 mg at night along with 125mg Lamictal. I used to only be on the Lamictal and became suicidal. In the hospital they added Seroquel to my regimine, and two nights later I woke up laughing in my sleep; the improvement in my mood was incredible in both its degree and its rapidity. Mild weight gain has been an issue, but I now just avoid sugar and simple carbs and exercise more. F 40 1 years
1/20/2008
 4  Anxiety & Depression Sleepiness and dry mouth (but both really did stop after 2 weeks). Awesome sleep continued after the sleepiness stopped. Antidepressants or benzos work by "compensating" (for depression or anxiety or mania). Seroquel works by "normalizing." So at a low dose it works for insomnia and at a high dose, it works for schizophrenia. For me, Seroquel really helped stop suicidal thinking. Since it's great for PTSD, it got me to finally acknowledge and deal with having been an abused child. I never realized how much supressed memories were messing me up every day. I have to credit Seroquel(100mg 2x/day) for giving me the strength to deal with this -- something that years of SSRIs couldn't do. After being on Seroquel for 6 months, I downgraded to benzos for a year and then to nothing. Hopefully I'll continue to stay well. The two biggest problems with Seroquel (my opinion) are: 1) It "turns off" your ability to feel hungry or full, which means that you overeat -- and gain 30 pounds in the process. If you know this -- and can measure portions instead of trusting your F 40 6 months
1/20/2008
 1  depresssion sleep problems Dry Dry Dry mouth chest pain strange feeling slept 10 hours woke up felt drunk and tried I felt like I was on fire This is the worst medicine I have ever taken. It gave me the sickest horrible nightmares And I dream the same nightmare twice. I couldn't wait until this garbage was out of my system. This drug is Creepy.... Do not take this stuff.... F 46 1 days
1/20/2008
 4  anxiety,insomnia 58 6 days
1/19/2008
 1  bi-polar Weight gain. We thought Seroquel was working a little for our daughter (now 11, she started at 9). But when it seemed to be working less well, the dosage would be increased. Finally, after maxing out on the dosage, we came to the realization that this drug was a disaster. We think all it was doing was making her tired. So the combination of the rage of bipolar disorder and tiredness was making her even worse. We dropped it and tried Risperdal, which was her wonder drug. Without Risperdal she was heading toward institutionalization. F 11 18 months
1/19/2008
 1  Secondary insomnia VERY drowsy in the am. After 1 month, dose increased from 50 mg to 100 mg. Now I feel like a zombie. I am going to stop taking it. VERY scary dreams - Freddy Kruger type dreams where u are in a dreamlike state and wake up trying to talk/scream. Sugar cravings, eating in middle of night (which I have NEVER done). My doc prescribed this for "secondary" insomnia. He says if you find your thoughts racing at night, this drug will shut off your thinking. I feel like I am losing my mind now, harder to fall asleep now, afraid of falling asleep. I don't get it, I have always been "pretty together" as a person. I feel crazy now. I am going to stop this insane junk. F 49 2 months
1/18/2008
 4  bipolar, anxiety, insomnia restless leg This drug has helped tremendously with my panic attacks and depression. I am sleeping through the night consistently. 100 mg a day don't help me sleep as heavily as I'd like, but 200 mg increases the restless leg problem which lasts about an hour before falling asleep. I have not experienced any noticeable weight gain. I have not had as much help with my anxiety and depression as I have had with Seroquel. I couldn't imagine taking more than 200 mg a day, though.. F 32 6 months
1/17/2008
 3  ocd drowsiness and insomnia at the same time, severe restless leg syndrome took only one dose in my life, which was larger than what the doctor prescribed. first effect noticed was an euphoric calm-like feeling after which a state of intense drowsiness followed, also accompanied by insomnia and restless leg syndrome. it was a horrible state as i couldn't do anything because of the drowsiness but couldn't sleep either. M 19
1/16/2008
 3  schitzoaffective disorder/insomnia Fluttered heart beat, inability to walk, extreme dizziness, difficulty swallowing, 15 pound weight gain, severely anxious, trouble speaking and thinking clearly, very vivid nightmares Although there are sometimes terrible side effects when I take it at night, i would never get off of it because it's the only thing that will put me to sleep at night since I have racing thoughts due to bipolar disorder. Definitely an excellent drug for insomnia but just like any drug there also can be some pretty serious side effects. F 20 5 months
1/14/2008
 1  Depression Gained 12lbs in one month. Extreme hunger and thirst. Extremely hard to wake up in the morning, and very sleepy throughout the day. Tendency to nod off at my desk. Erratic sleep: I can sleep 15+ hours on this medication one night, and the next sleep three hours and be wide awake at 3 in the morning like I am right now. Tossing and turning all night, waking up with heart racing. General confusion and in a constant state of being out of it. Feeling very hot and sweaty. Lately I sleep with just a sheet and the window wide open (mind you that it's 10 degrees outside). F 25 33 days
1/13/2008
 5  Bipolar II This drug SAVED my life, despite the 15 lbs I put on, I feel like I have never felt before. I have been on many antipsychotics before, and the side effects were brutal, but with Seroquel @ 300 mg I don't have ANY side effects, I take it @ 9pm, around 11pm I start feeling groggy by 3am i'm fine, up at 7am and feeling wonderful, the only thing is my appetite, I was allways thin, not so much anymore, but I was never so happy in my life, and so at peace, like I'm now. F 28 4 months
1/12/2008

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