LUPRON DEPOT Reviews (LEUPROLIDE ACETATE)

Average Rating: 3.0 (783 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION ANTINEOPLASTICS

 Type: Rx Drug

  

LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on LUPRON DEPOT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LUPRON DEPOTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Endometriosis I'm currently receiving an injection of 11.25 mg of Lupron Depot every 3 months. The pain I was having due to my Endometriosis has gone away completely, however, I am experiencing a lot of hot flashes and mood swings. I also lost 8 lbs in a matter of 3 months which does concern me as I'm only 5'3" and now weigh 104lbs. I just started a new medication to help with the hot flashes. Everyone is different and the negativity about this medication made me leery at first. The only thing I have negative to say is the hot flashes can be HORRIBLE at times (but I learned to dress in layers and wear light clothing), but I'm willing to take them over the pain. If you're considering Lupron Depot, just remember that everyone is different and your side effects could be minimal like mine.... it's worth a shot! (no pun intended) :) F 26 3 months
11.25mg 1X O
1/5/2011
 4  endometreosis. pain one bout of severe menopause like symptoms after first shot. hot flashes, nausea, dizziness At age 19 had a abdominal surgery for recurrent endometriosis and severe abdominal adhesions. Did a three month course of Depo Lupron. Immediately after went on Yasmin. Since then I take three months of active pills before having a period. This in theory is to prevent the endo from having a chance to come back. I am 26 now, have no recurring problems, have been scoped again for endo, and they found nothing. I am told that as long as I'm having periods, there should be no concern about having children in the future. F 26 3 months
1X M
10/8/2010
 4  Endometriosis Hot Flashes, extreme weight gain with inability to loose any weight, depression, anxiety Even with the side effects, I would prefer dealing with them more than the 14 years of agony I went through before I was diagnosed and put on the lupron therapy. After almost three years on the shots, I will still go religiously every 12 weeks for the shot until I decide to try to conceive. The first three months of the shots are the worst. After that you are so used to everything that the side effects don't seem that bad anymore. F 26 2.75 years
10/28/2005
 4  endometriosis hot flashes, insomnia, and weight gain I have had my first scope for endo and this drug has done wonder's for it F 26 4 months
1/24/2009
Email
 4  Endometriosis Fatigue, bad lower back and legs pain and hot flashes F 26 3 months
2/25/2009
 4  Severe Endometriosis Hot flashes, weight gain, fatigue I am nervous about the long-term effects that I have heard about with this drug. However, my side effects have been very manageable (though the weight gain is a bit maddening) in comparison to the pain I was in with my endo. I had surgery and was hospitalized with a post-op infection two weeks after my surgery, but other than that, it has worked very well for me. Everyone needs to remember that medications affect everyone differently, so don't dismiss something simply because others have had a bad reaction. I was TERRIFIED to start this shot because I don't have the best health, but I'm glad I did. I just need to try and remain positive about my future now. Best of luck! F 26 1.5 years
1/3 months 1X O
7/10/2015
 3  Endo Migraines, hot flashes, night sweats I had my first injection 2 weeks ago. Since then I have had 2 major migraines, one ending me up in the ER. I had never had a migraine before. I am on the 6 month treatment and I'm not sure I can make my self go back next month. Hot flashes aren't bad, funny for my 26 year old body that's always cold to experience. Night sweats are tolerable, just have to get used to waking up dripping wet. F 26 2 weeks
5/1/2008
 3  ENDO FIRST MONTH INSOMNIA, NOW IN SECOND MONTH AND NIGHT SWEATS, HOT FLASHES, MOODSWINGS, TIREDNESS, IRRITABILITY, MEMORY LOSS AND HEADACHES NOT SURE HOW I REALLY FEEL ABOUT THIS TREATMENT. PAIN IS BETTER BUT ALL THE SIDE EFFECTS DRIVE ME CRAZY. I AM ON ADD BACK AND ALSO TAKING WELLBUTRIN XL TO HELP WITH THE MOODSWINGS AND DEPESSION. THAT IS HELPING BUT THE MEMORY LOSS AND TIREDNESS IS NOT GOOD FOR ME I HAVE A 5 YR OLD SON WHO NEEDS ME TO PLAY AND DO THINGS WITH HIM AND I AM JUST TO TIRED THESE DAYS. PLEASE IF ANYONE HAS ANY ADVICE EMAIL ME. F 26 2 months
11/1/2005
 3  Shrink lrg fibroid/prep for surgery mild hot flashes (not that often) noticed them more after my 4th shot, night sweats and weight gain. Emotions weren't too bad, what I noticed most was that I started getting a short temper, which is not like me. My doctor recommended Lurpon in hopes that it would stop my heavy bleeding (which it did) and shrink my very larger fibroid that was crushing my right fallopian tube, my bladder and growing into the endometrial cavity and other ways. I was told I pretty much had 3 diff types of fibroid in 1 and that it was a little bigger than grapefruit size. I had 4 shots 1x month for 4 months. After reading a lot of comments on here...I thank god that I didn't have that bad of side effects (and am sorry for those that did and had to go through that crap). The side effect that I had the worst was the night sweats and now being that my last shot of Lupron was 2-18-13 I'm not having any side effects except for sometimes light night sweats and I now have an acne break out on my bottom/upper thighs. Not sure if the break out is from the Lurpon or sweat, but the sweating is from the Lupron so I guess technically it is. Anyways, as I said I did not suffer from the side effects too bad, but I don't know about recommending this medicine? I chose to trust my doctor and if it did shrink the fibroid that would make the myomectomy easier and less risk of possible hyst or loss of tube. Overall...my fibroid did NOT shrink at all, but oh well. Fortunately my doctor was able to remove fibroid and keep everything else in tact and after healing should be able to have children! F 26 4 months
1X M
4/6/2013
Email
 3  Severe Endo, Heavy bleeding My lower back hurt some, not sure if I can say that is from the shot! I read all the post's and was not going to take this shot at all after reading all the horrible experiences others have had from this shot. I spoke to my doctor and decided to give it a try. I just took my first shot yesterday and feel fine. Now the side effects might come later but for right now I feel like I usually do. I thought right after I got the shot I was going to have a hell of a time because of the horrors I read on here, but again nothing yet. I will post in a month, I hope if I do experience side effects they ae not to bad. F 26 1 days
8/2/2007
 3  Severe Endo and Anemia! Mve some aches in my lower back, hips and legs! Nothing Asprin did not help so far! I have only had one shot on the first of August! I have had some aches in my lower back, hips and legs but asprin at this point has helped me! I am not taking the add back therapy I am actually taking Yaz the birth control pill with as my GYNO says it helps better with the side effects! I came to this website and was horrified and did not want to take this drug and fought my GYNO on taking it. So far so good, but this is justmy first shot so who knows. Here is my journal address. I will on a daily basis note my condition so please come: http://journals.aol.com/narwood25/my-endometriosis-diary/ F 26 8 days
8/8/2007
 3  chronic pelvic pain,heavy periods HOT FLASHES GALORE,cramping-rt side pelvic area,wiped out feeling,discharge,emotional rollercoaster,HOT FLASHES,arm and leg pain, HEADACHES I cant stand the side effects and wont be taking it anymore. It was great for the simple fact that I no longer got my period, but the way it makes me feel all month just isnt worth it. F 26 6 months
4/11/2005
 3  endometriosis depression,crying,extreme moodiness,headaches in the first 2 weeks I have just recieved my first shot of Lupron. My emotions are going crazy. I keep thinking my life is falling apart but it is all the effects the lupron is playing on me. I don't know if my daughter and boyfriend can take much more of me. I havent even began experiencing the other symptoms yet. F 26 2 weeks
5/10/2005
 2  Endo,Irregular bleeding,Anemia I have not experienced them yet, however after reading all of your comments I really think I am not taking this stuff! On June 22, 2007 I had a laparoscopy and a DNC, before I had these procedures I was hospitalized for Severe Anemia do to heavy blood loss from a month long period and had to have a blood transfusion. Other than the Severe Anemia and the very irregular periods I had no pain. My OBGYN stated I will bleed to death because of the Anemia if I do not do something about the issue. So I had those two procedures and I thene found out I have Severe Endo. Ever since these two procedures I have had nothing but headaches and stomach cramps and pains. I am now to go on lupron dupot for 6 months and then if that does not help with the severe endo I have to have a hysterectomy! After reading all these comments about this drug, I know I cannot handle those side affects. I just wanted to thank all of you for your honest opinions! F 26 0 days
7/12/2007
 2  endometriosis, ovarian cysts hot flashes, night sweats, mood swings, decreased libido, memory loss, decrease breast mass, decreased muscle mass and tone, fatigue, knee pain I decided to try Lupron after living in constant pain since I was 18. I lived on pain killers for two years before I realized this was not a way of life. I have had surgery every year since I was 18, I am now almost 25. I started Lupron successfully at first. At almost one year, i had developed yet another huge cyst on my ovary and my endo. was out of control. My doctor and i decided Lupron did not help me, so I stopped the treatments. Now, almost a year later, my normal periods have returned. I still have pain, but now I suffer from PMS symptoms when I never had before. I have hot flashes still, i am highly emotional, my memory is not sharp, and i feel that my hormones are "out of whack". All of this i attribute to Lupron. Although my pain has dissapted somewhat, I do not feel that this drug was right for me. I know that it has worked for others and I am happy for those people. I only wish it could have worked better for me and that i did not still suffer from its long term F 26 1 years
3/7/2006
 1  endometriosis, adnomyosis Terrible hot flashes, fatigue, knees aching. Now my vision keep blacking out every 3 minutes. I still have the same pain I had from the begining, only difference I have the pain daily. I'm weighing my options about having a hysterectomy. I wish some one would have told me about these side effects. Very in happy F 26 9 months
11.25mg
2/25/2012
Email
 1  Ovarian Cyst + endo Hot flashes, insomnia, irritability, anger I would not recommend this drug to any woman who cares about having any kind of a sex drive. I took lupron for 6 months almost 4 years ago when I was 22. I am now 26 and have no sex drive whatsoever, and it's killing my boyfriend. I have no desire anymore at all. I wish I would have been given other options, or I wish I would have reseached this drug more. I am sitting here crying reading some of the comments because they are all what I feel. Also, my anger has increased since taking the shots. I seem to fly off the handle over little things now, and it seems to be getting worse. My legs and ankles ache all the time now, and I'm not sure if it's from the lupron or not, but I read other people have aching joints as well. Please, if you're told you have to take this, ask tons of questions, and see if there are other options you can try! Good luck to those of you who are taking it. I hope it turns out differently for you than it did for me! F 26 6 months
8/2/2007
Email
 1   M 26 1 months
6/18/2003
 1  yes contant bleeding, b/w light and heavy bleeding for now 12 weeks now DON"T DO IT!!!! Unless you have spoken to your doctor about the your past history including blood clots and depression, nothing was asked except if " i had unprotected sex within the last two weeks" that's it and then it was given to me, injected in my buttox, (I don't know it the location has anything to do with it", the first time i got it my arm and i had no problems" I don't no also if your hormones change signicantly after you have a baby that might have somthing to to with it, but i've been bleeding for 12 d@#N weeks now, and i'm mad, my advice DON'T DO IT at all F 26 4 months
11/18/2006
Email
 1  endometriosis Lupron ruined my life!! At first I was all for feeling better but I'm regretting ever letting that needle touch my skin. I started lupron after the birth of my second child. I had tried 17 different birth controls that could possibly help or hinder the pain from the endometriosis the one that did help got recalled. I figured wth might as well give it a try. Worst mistake ever! The doctor did not give me a pamphlet just told me of the hot flashes. The first week the hot flashes came and went all day every day. I then started feeling dizzy and faint. My energy was gone. By week 6 I started having signs of a uti so got azo and prescribed meds little did I know it wasn't a uti it was a side effect. My kidneys began to hurt. It hurt to breath it felt as though I had an elephant sitting on my lungs.Then my whole body started to weaken to the point I couldn't open a jar that had previously been opened. My muscles and bones ached it hurt with every little movement. My body then began to swell(this side effect is still with me it's been several months since I've had my last dse) my ankles swell the second I put them on the floor each mornings the rest of the body parts soon follow. I had lost all interest in sexual activity.I soon got depressed I felt worthless couldn't even play with my kids. My marriage got rocky bc of how I felt. I started getting bumps under my skin on my neck, shoulder and back and it was very painful. My primary care physician said shingles but i don't think F 26 3 months
1 shot
7/14/2014
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