LUPRON DEPOT Reviews (LEUPROLIDE ACETATE)

Average Rating: 3.0 (783 Ratings)

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 ANTERIOR PITUITARY HYPOTHALMIC FUNCTION ANTINEOPLASTICS

 Type: Rx Drug

  

LUPRON DEPOT  (LEUPROLIDE ACETATE):  Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.   FDA Approval Date: 1989-01-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LUPRON DEPOT: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LUPRON DEPOTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Endometriosis Hot flashes MAJOR!! And big time lack of sex drive...which is SOOO no like me!! weight gain in the abdominal area, kind of like a guys beer belly :( I found my miracle drug!! I'm 27 Y.O and have had endometriosis for about 10+ years...severe bleeding to the point that I'd pass out, severe pain to the point of missing school and work, it was miserable...then my Dr. told me about Lupron and I agreed to take the regimen. Ends up that's just what I needed, I took my last of 6 shots October 29th and I'm now waiting to see what will happen now, I haven't restarted my menstrual cycles to know if there will be any pain but that's definitely not a problem, I just wish the sex drive would come back SOON, and so does Hubby!! F 27 6 months
12/5/2005
 5  Endo Hot flashes/sweating, fatigue, irritability, mood swings, weight loss, exhaustion I have two months to go on this, and although it's not as bad as I had thought it would be, I can't wait to be off of it. I just hope that the pain doesn't come back. It has made my life better because I'm not suffering with extreme pain three weeks out of the month, but I'm exhausted all the time, and I have dark circles under my eyes that won't go away. I honestly would do this therapy again down the road, but it makes for a rough time. The hot flashes and sweating aren't so bad---being exhausted all the time is the hardest. I started losing weight and have been eating junk food to try to fatten myself up. The nurse told me I should be exercising, but I'm so tired all the time, my joints ache, and I don't want to lose any more weight! My first surgery wasn't succesful due to the severity and build-up of the tissue. I honestly wanted a hysterectomy, but because I haven't had kids, my doctor advised Lupron---(at this point I'd rather adopt.) I was scared to go on the drug afte F 27 4 months
8/27/2005
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 4  SEE LAST POST BY THE WAY, YOU ALL SHOULD BE AWARE THAT ALTHOUGH YOU PUT A RATING ON HERE OF ONE NUMBER, THIS SITE AUTOMATICALLY CHANGES IT TO A 5. I ACTUALLY GAVE IT A 4. BEWARE. F 27 6 months
3/14/2006
 4  Endometriosis and Fibroids Oh my, let me tell you, hot flashes that made me feel like I was in an inferno! TAKE NOTE OF THE TIME YOU GET AN EXTREME FLASH, you will notice that they happen around the same time everyday! In the beginning, some extreme headaches, but they subsided once in the second to third month. Can't say that I miss having my period, I only had one short cycle in the first one to two months. The relief of the PAIN I would be in means alot however, in spite of the 20lbs+ that I gained. I too mostly gained around the mid-section. I have never been this size in my life! So be ware on that! I also don't have much of a sex drive, not sure if its the meds or not but I think I'm more detached than ever! Night sweats are also a factor, I sleep with a fan blowing directly on me at night, every night! I still have another month to go and I am scheduled for the last shot the end of next week. Some mood swings and irritability is a factor.I can not tell you how happy I am to be leaving this medicine behind Perhaps they should come up with a way to deter the weight gain, or atleast explain the process for the weight gain. F 27 6 months
3/14/2006
 4  Endo, fibroids Weight gain, severe cramps (for about the last 3 days) depression... This is my 2nd treatment of lupron, my first was about 5years ago post lap, and after my 6month treatment i got pregnant.. Now the endo is back with avengance so my doctor decided to try thr lupron again to help with the pain. Both times I have have weight gain , and this time I have a lump where I got my injection that hurts like heck and won't go away! anyone else experience this? F 27 14 days
9/6/2006
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 4  Endometriosis Stage IV Vomiting, fatigue, very emotional, tremors, dry mouth, hot flashes, acne, hair loss, memory loss, bone pain, and pelvis pain. The side effects suck, but they are worth delaying the endo from returning. F 27 3 months
3.75 mg 1X M
1/12/2011
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 4  Endometriosis Hot Flashes, Weight gain, mood swings I took two shots that lasted six months and the side affects have been pretty minimal. I have had mild hot flashes and tend to get hotter easier. My husband seems to think I have mood swings, my doctor prescribed lexapro when I got my first shot to help with the mood swings. The side affect I dislike the most is the weight gain. I have put on anywhere between 10-15 pounds but most seems to have come on after the second shot in September. I would suggest keeping a workout schedule to try to keep weight gain to a minimum from the beginning. I have been trying to lose weight while on the shot and nothing seems to give. Overall I would say the Lupron shot has worked very well, I can live with a little extra weight. F 27 6 months
2X O
11/14/2011
 4  severe endometriosis I just took my 3rd month shot yesterday. Honestly, I only experienced severe pain during my menstrual cycles. I mean it was debilatating pain. It wasnt until I started taking this shot that the pain stopped immediately. No periods, no cramping, mild hot flashes, mild night sweats. Nothing too bad. Sometimes i feel like I am losing my mind, i forget a lot of stuff. Oh and my sex drive is all there, but I am very dry, like shredded wheat. But nothing a little lube wont solve. I am halfway done with the treatment so my prayer is that things will be a whole lot better for me when trying to conceive. I will be getting married in 2 months so a pregnancy after this treatment would be the perfect gift for me and my soon to be husband. i have not experienced any weight gain, maybe some water weight. Overall I am happy with it thus far. The only reason i rated it a 4 was because i am not finished with the treatment so i dont know if it helped me a great deal yet. but i am very satisfied so far n I've noticed in reading a lot of different forums, that the shot seems to have a different effect on women older than 30. I notice in the blogs that they experience a lot of pain and the side effects are far worse. I wonder if this can be a factor in considering taking this medication. One should also take into consideration that there are more negative reviews than positive reviews, so that may be a factor as well. Also I was advised that it is recommended that this treatment be only done once and that this is only a temporary cure, 3 - 5 years. I am a recent survivor of pulmonary embolisms in both lungs as a result of birth control and had fears of taking this medication. I was advised that the hormone that causes the embolisms (like that in BC) is not in this shot, HOWEVER, the pills they give you to ward off the side effects DOES include this hormone and one should not take it if you have had previous issues with blood clots. Even still while on this medication, i am very cautious and pay a lot of attention to cramps and breathing for safety's sake. At the end of the day, there is no harm in trying this medication. I would have went to the end of the world and back to find a cure for the pain i was having. Its always worth a try, but it is never worth your life. Pay attention to the side effects and and your body. GOD BLESS F 27 6 months
3.75 MG 1X M
5/9/2012
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 4  endometriosis HOT FLASHES, night sweats, weight gain, mood swings I am a phisician and F 27 3 days
9/29/2004
 4  Endometriosis Bad hot flashes, headache, nausea, mood swings, crying spells I just received my second shot on Tuesday. The doctor told me that I should not have anymore pain after my third shot. He gave me add back therapy for the hot flashes and other side effects but I have only taken them for three days. So far I haven't seen any change. Does anyone know how long it takes for them to start working? F 27 2 months
1/18/2007
 4  Endometriosis and Dysmennorhea weight loss, Moderate headaches, urination frequency, hot flashes, tiredness. It should be used as a last resort prior to hysterectomy. You must outweigh the possible side effects/compared to the state of disease itself. All medications have side effects. Personally I do not regret the decision to start Lupron Therapy. I am also on HRT LOW DOSE, and it has helped with side effects. F 27 1 months
1/28/2007
 4  Endometriosis headache (pretty bad at times), Minor hot flashes, no appetite I underwent a partial hysterectomy at 26 to stop excessive bleeding. Also had ovarian cyst's and endo. Three months later had to have my right ovary removed. Now almost six months later still have severe pain from the endometriosis with only one ovary in me! Just started Lupron yesterday and so far I love the results! Any one else already had a hysterectomy??? F 27 1 days
5/3/2007
 4  Severe Endo with Severe Anemia I have experienced night sweats a few nights a week! I am happy to read the more postive experiences as when I first came to this website every post was negative. I am having a positive experience. I recieved my 2nd shot on 8-29-07 and I have yet to experience a hot flashand but have experienced night sweats which is not a bother to me! Throught the remainder of my treatment I hope it goes as smooth as it is now! So far my experience has been great and I have not suffered from many of the side effects assoicted with this medication! 27 2 months
9/13/2007
 4  Endo Hot flashes, night sweats, mood changes,body aches,tired,stomach problems,cant sleep, I will be getting my 4th shot next week.I have been pain free for 2 of the 3 months that I have been on this.Yes the side effects are not always nice but are manageable. I do see this is helping. I only had a few days of pain since I started this. Dont let other reviews scare you.Everyone is different and all things help others in different ways. If you want to try to get rid of your pain,its worth a try. F 27 3.5 months
11/26/2007
 3  endometriosis,fibroids, Adenomyosis terrible hot flashes,extreme fatigue,restlesness,depression,aggitated,cold,empty feeling,hair loss,weight gain. has anyone else experienced hair loss. my doctor says its normal to experience alot on these shots and i was put on hormones to help calm me with no success.i am on a nine month regimen with it. and the symptoms got so bad i stopped for two months before the hubby made me go back and finish the therapy. no fun F 27 6 months
9/13/2009
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 3  ENDOMETIROSIS HOT FLASHES, SEVERE MOOD SWINGS, VERY IRRITABLE, HEADACHES, UNABLE TO FOCUS FORGETFULNESS. NOT SO MUCH INSOMNIA BUT RESTLESSNESS!!!!! I HAD SEVERE PAIN BEFORE THIS SHOT AND NOTHING WOULD HELP. AFTER TAKING THE SHOT I CAN SAY THAT THE PAIN HAS REDUCED DRASTICALLY.SIDE EFFECTS ARE TERRIBLE. I AM A VERY ORGANIZED PERSON, NOW I FEEL LIKE I CAN'T THINK STRAIGHT, I LOSE MY TRAIN OF THOUGHT EASILY AND I AM EASILY DISTRACTED VERY FORGETFUL, IT JUST SUCKS THAT YOU SUFFER IN PAIN THEN WHEN YOU GET THE RELIEF YOU WAITED FOR EVERYTHING ELSE FALLS APART. THE FACT THAT I HAVEN'T HAD A GOOD NIGHTS SLEEP IN 3 MONTHS DOESN'T HELP THE SITUATION ANY EITHER. I HAVE TROUBLE FALLING ASLEEP, STAYING ASLEEP AND MY WATER BILL IS HIGHER BECAUSE OF ALL THE SHOWERS FROM SWEATING SO BAD. AT TIMES I DON'T EVEN WANT TO GET UP AND GO. THE SEVERE PAIN IS GONE BUT I DO HAVE PAIN AND CRAMPS NOW AND THEN THEY JUST SEEM TO PASS OCCASIONALLY WITH ANAPROX FOR THE PAIN. F 27 3 months
8/13/2009
 3  endometreosis Flu like symptoms a couple of days after getting the shot, severe weight gain, mood swings, lower back pain While the shot improved my overall pain, the side effects were much more alarming. The fever/chills, flu like symtoms,migraines and panic attacks were very scary. F 27 4 days
11/1/2004
 3  ENDO MOOD SWINGS, SEVERE HOT FLASHES, SEVERE WEIGHT GAIN... iT HAS HELPED WITH THE PAIN, BUT THE PAIN IS NOT COMPLETLY GONE. I'M ON MY 4TH SHOT. i HAVE GAINED A LOT OF WEIGHT AND IT IS HARD TO GET IT OFF. F 27 4 months
12/21/2004
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 3  Endometriosis At first I was taking one shot a month and I experienced the worse! Extreme fatigue (still have) severe migraines, crazy night sweats, hot flashes sweat was literally pouring down! I also take hormone pills to calm down the side effects. I lost 7lbs on the month to month. Now I am on the higher dosage taken once every three months. Good thing I no longer get the horrible periods and heavy bleeding that just completely stopped. Now it's more so dry mouth vision problems, I'm extremely extremely tired I'm constantly calling out of work because I have no energy. I've gained my 7lbs back appetite is extremely large I eat so much! Honestly I feel preggo and I don't even know what that feels like! Just can't wait til this therapy is complete don't wanna lose my job! F 27 6 months
1 every 3
11/28/2012
 3  Endometriosis hot flashes, headaches,muscle and joint pain, dizzyness , fatigue This is my first month on the shot so I guess my body is gonna be alittle out of wack at first. I haven't had any break through bleeding because I am on an add back medication. I am also on an anti-depressant which has helped with the mood swings I guess. I have noticed some relief in the pain. I am still having some pain but not like before. After two surgeries and many years of pain this medicine seems to be helping me I'll let ya'll know how shot 2 goes F 27 1 months
2/9/2007

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