MACROBID Reviews (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE)

Average Rating: 1.7 (1815 Ratings)

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 ANTISEPTICS,URINARY TRACT

 Type: Rx Drug

  

MACROBID  (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE):  This medication is an antibiotic used to treat bladder infections (acute cystitis). It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. This medication should not be used in infants younger than 1 month old (see also Precautions section). This drug should not be used to treat infections outside the bladder (e.g., kidney infections such as pyelonephritis or perinephric abscesses).   FDA Approval Date: 1991-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MACROBID: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MACROBIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  UTI Bad headache on 2nd day of meds, malaise, after first 2 doses, had a strange tightness in the chest and a dry cough, increased heartrate The bacteria I have now are resistant to Sulfatrim and Cipro...so the doctor reluctantly put me on this (I have very recurrent UTIs). This is the third time that I'm taking it. Several months ago, it worked fine (I just felt sleepy). The second time, I think it started to help my UTI, but it never eradicated it, but thats possibly due to not taking them for long enough. This third time, I have a very bad headache and just feel like lying in bed all day...I just pray it gets rid of the infection. F 21 7 days
2/25/2009
 1  UTI Severe hives, swelling on face, hands legs and feet. Ive had never felt this miserable in my life. I was constantly scratching all over, one place stop itching then another place starts, it was a worst experience I've ever had with any drugs. I ended up going to an ER in the middle of the night. They gave me a couple shots of benedryl and steroid. The doc told me to take antiacid also. It took me a couple days to actually get rid of swelling. Oh, yeah, I am also allergic to sulfer. F 40 10 days
2/23/2009
 1  bladder infection/uti This is my second time to take this medication and on the 4th day I started to get an excruciating headache, muscle and joint pain, itching on feet and belly and general flu like symptoms. My last dose was over 48 hours ago and I still have all these symptoms. I am taking generic Macrobid F 27 4 days
2/22/2009
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 1  uti I have taken macrobid before with no problems. This time after taking macrobid for 6 days I woke up with hives within a few hours they were so bad on my legs I looked burned. I went to insta care they told me I was allergic to macrobid and to take benadryl. I did this. I worsed all day getting a fever and flu like symptoms. Later in the evening I got a bad pain in my chest and felt like I couldn't lay down. I got sick to my stomach in the night and got up to go to the bathroom, at which time I passed out. I was rushed to the hospital. This is the sickest I have ever been!!! I was on generic nitrofurantoin 00378-3422-01 batch number 300 7011 F 53 6 days
2/20/2009
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 3  UTI Flatulence, headache, dizziness, mild to moderate flu-like symptoms which included: body aches, mild mood change, perceptual changes, mild sore throat, runny nose, headache, etc. Also had some difficulty concentrating. It did seem to help with the UTI. I felt OK the first 3 days then started feeling like I had the flu. Took for 6 days then stopped as side effects were getting worse. Side effects began to abate about 14 hours after my last pill. M 47 6 days
2/19/2009
 3  chronic recurring UTIs preventative I used the generic for Macrobid as a preventative and treatment of UTI's for about 2 years. After a year and a half I started getting hives about 8 hours after taking a macrobid pill. It took me a while to figure out. At first I would take it at night and wake up with hives, which I mistook for some kind of bug bites ALL over my body. It happened at my mother's house, my house, my partner's house and finally when I took it in the morning and the hives showed up in the evening I knew it was an allergic reaction to the macrobid. My hives never lasted more than 3 hours at a time and did not always happen when I took the macrobid. I learned I'd developed and allergy and that with time my allergic reaction(s) could become more severe. I have also been exhausted for the last 2 years, but the exhaustion could be due to a general decline in health and other things like problematic sinuses. I am a smoker, so I don't know if the worse condition of my lungs and respiratory health over the Macrobid worked for me, till a year and a half when I developed an allergy. It was really great to be able to have sex, take a pill and not wake up with a UTI. Now that I have reported the hives to the Dr, I've been taken off the macrobid, and now I don't know what I am going to do, because I am sure my UTI will be back by tomorrow. I no longer have any antibiotics and the Dr says other antibiotics will cause yeast infections, and have higher risk of even worse side effects. I'm back at square one and have to manage somehow to go in and give a urine sample when I have an all out infection. I have also developed an allergy to all the creams for yeast infections. So next time I am given an antibiotic I will have to take several doses of diflucan to combat a yeast infection, and each dose of diflucan is hard on the liver and kidneys...which have already had a beating with 2 years of macrobid use. F 26 2 years
2/17/2009
 4  uti nausea, fatigue im taking the generic macrobid for 7 days 2x a day. 1day was a breeze, probably because I took my 1st dose before bed. 2nd day was complete hell with nausea, headache, and vomiting! 3rd day was different, my morning pill made me sick but my bedtime pill didn't. 4th day was the same, morning pill had the worse vomiting but my bedtime pill didn't. that's when I realized I should take the pill an hour after eating (not with food as the pharmacist told me, could just be me). today is the 5th day and this morning was fine since I waited the hour (plus munching afterwards! once your tummy is empty all hell breaks loose! I munch on cap'N'crunch). I do have slight heart burn from the pills but every thing gives me that. my last pill will be weds morning. as long as I don't have any of the weird allergic reaction a lot of these other ladies experienced ill be fine and im not going pee every 20min which is a plus! F 26 7 days
2/8/2009
 1  uti extremely itchy hives all over my body after taking it for a week. Stopped taking it last Thursday and here it is Monday and I still have horrible itchy hives. Was prescribed prednisone last thursday and almost done with pack and still not helping. Also taking benadryl every 4 hours. This medication sucks. I cant get rid of itch hives after stopping it 4 days ago. I am suffering with itchy hives and have bad indigestion/heartburn from it as well. Not going away and starting to get anxious as to when this reaction will subside. I have almost finished my prednisoe pack and it is still very much here with hives and intense itching. This medication is awful. I am also allergic to sulfa drugs. M 41 7 days
2/2/2009
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 4  bladder infection I am pretty lucky i guess no side effects just a little gas. very happy my bladder infection is gone It was making me so uncomfortable without this medication my life would of been at risk! F 26 6 days
2/1/2009
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 1  UTI I took this med for 4 days then developed hives so bad that I was out of work for 12 days no, I didn't make a mistake it was 12 days of pure HELL. I could not walk and I scratched my palms so much they were blistered.I never itched so bad in my life.I had to go to the emergency room twice during this time. The Doctor at the hospital said never take this again (no s***)or anything that has sulfur in it and that is what I stick too!!! I think I said it all!!! F 35 4 days
1/29/2009
 1  UTI No fetal Heartbeat Was nearly 9 weeks pregnant when doc called to place me on this drug for a UTI. At the 11 week check up there was not fetal heartbeat. The fetus was dated at 9 weeks and 2 days. Called it a missed miscarriage. F 34 5 days
1/27/2009
 3  UTI general aches and pains, headache, itchy rash (hives?) on thighs, knees, and elbows. I have lupus though so everything but the hives might be just part of a bad week rather then specific side effects. I am not aware of any drug allergies and these are the first hives or reaction I have experienced. This did seem to work for the UTI symptoms but I had one day of Cipro before switching to this antibiotic. I was switched off of Cipro because I was told Macrobid was safer for pregnancy. After 3 days of taking it I started to develop an itchy rash which got worse the next day. Stopped taking it after the fourth day and on day 6 the rash seems to be slightly better. Not sure if it's an allergic reaction to the medication or something else. F 33 4 days
1/26/2009
 1  A supposed UTI Chills, headaches almost migraine like for going on 8 days now; complete lethargy, body aches, loss of appetite, I was prescribed this for a UTI, but had absolutely no symptoms of such. I had only 6 doses of this medicine and honestly thought I was dying of goodness knows what. ALL blood work, etc., has come back completely normal; CBC, liver/kidneys all normal or negative. I originally went to the Dr. about ovarian pain. The only thing my GP and I can seem to come to, is this medicine and can you believe it says Allergy to sulpha drugs ON MY/IN MY OB/GYN CHART ? Thank goodness my G/P had the presence of mind to take me off; I still had 2 more days I was supposed to take. But what can you expect from my OB who clearly took no time to refresh his memory about me...he asked this client after say 4 visits over 3 years if I'd ever had Children!!?? That answer would be no. I'm not surprised he missed this and needless to say, he's been fired. And know for all you folks out there who didn't/don't/won't complain; they'll never get any better about such things if they don't feel some pain. And as so F 49 6 times
1/26/2009
 1  Chronic UTI 10 minutes after I took my first pill I started itching all over my body even my gums! I felt really hot and I my head felt like it was going to explode. My heart started pounding, I could feel it in my ears and it was racing. I took 2 benedryl. I ended up at the ER. They took me straight in. By that time I had started to wheeze. They started an IV on me giving me steroids and I got a shot. I don't know exactly what is in this medicine but I am allergic to something. F 35 1 days
1/24/2009
 1  UTI swollen sensation in hands at first, then severe itching by day 4. I stopped taking it on day 5 (uti s/sx gone) but the itching still persists5 days post drug use. UGH! if anyone else has this problem please let me know how long your itching lasted.... F 39 5 days
1/19/2009
 1  UTI I took only one dose. First, I had severe itching on palms of hands and feet bottoms, then severe vomiting and diarrea at the very same time!! Eyes became blood shot. On my way to the emergency, my throat began to swell as did my tongue..my throat was closing in on me.Drs. in the ER immediately treated me with steroids other meds in an IV. Had to take a predisone tablets daily. Now, after almost one month I have Thyroiditis. This is a very dangerous medicine. Please, if you have contact with the FDA, I would recommend they take another look at this medicine before approving. The Dr. said I could have died had I not lived nearby a hospital. F 53 1 days
1/19/2009
 3  uti shortness of breath; anxiety Took once or twice a year for 5 or so years. Side effect was subtle and came after finishing med so I did not associate it. Thought I had breathing problems... would last a day or so. Last time, thought I was getting worse and saw the dr. He made the connection -- but thought my lungs were pretty good for age and ex-smoker; told me it was probably my "breathing center" -- i.e., it's all in your head! Did get rid of UTIs -- now I'm working on prevention. F 64
1/15/2009
 1  UTI/Kidney Infection 104 fever, headache, nausea, lethargy After 3 doses my 16 yr old daughter ended up in the ER to bring down 104 fever that would not respond to OTC fever reducers. They even checked for meningitis since the headache was so bad. Did nothing for the kidney infection. ER doc wondered why she had been prescribed this med to begin with. Ended up on IV Cipro. Will never use this med on her again. F 16 2 days
1/15/2009
 1  uti nausea, exhaustion, chills, probable fever (i have not had a fever for thirty years so don't even know where the thermometer is), flu-like muscle and joint ache, no appetite, feeling like skin crawling followed by itching and then hives. it did work for the uti but the price was way too high. (i took a generic version: mylan 3422 mylan 3422). would not have suspected a drug reaction without your site so thank you. side effects began at end of 7 day treatment, are still with me 3 days later, subsiding some each day. further research uncovered this worrisome information from medicinenet.com: Nitrofurantoin can cause acute and chronic liver disease. Most commonly, nitrofurantoin causes mild and reversible elevations in blood levels of liver enzymes without symptoms. In rare instances, nitrofurantoin can cause hepatitis. Symptoms of nitrofurantoin hepatitis include: fatigue, fever, muscle and joint aches, poor appetite, nausea, weight loss, vomiting, jaundice, and sometimes itching. Some patients with hepatitis also have a rash, enlarged lymph glands, and nitrofurantoin-induced pneumonia (with symptoms of cough and shortness of breath). Blood tests usually show elevated liver enzymes and bilirubin. Recovery from hepatitis and other skin, joint, and lung symptoms is usually rapid once the drug is stopped. Serious liver disease such as acute liver failure and chronic hepatit F 64 7 days
1/13/2009
 1  UTI diagnosis from Gyn Started with a low grade fever and stomach ache. Felt sick to my stomach so I didn't take the second dose felt fine the next morning. Took my dose with brunch, by dinner I had a high fever and stomach ache again. Forced myself to eat and took another Macrobid. By 1:00 am I thought someone was trying to pull my hips out of socket, horrible pain in my lower back, extreme chills, high fever, muscle aches, exhaustion! By day 3 my doctor sent me to the emergency room fearing my UTI had become a kidney infection, after being catheterized and having a CAT Scan kidney infection was ruled out and I was switched to another med. F 38 3 days
1/13/2009

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