MACROBID Reviews (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE)

Average Rating: 1.7 (1815 Ratings)

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 ANTISEPTICS,URINARY TRACT

 Type: Rx Drug

  

MACROBID  (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE):  This medication is an antibiotic used to treat bladder infections (acute cystitis). It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. This medication should not be used in infants younger than 1 month old (see also Precautions section). This drug should not be used to treat infections outside the bladder (e.g., kidney infections such as pyelonephritis or perinephric abscesses).   FDA Approval Date: 1991-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MACROBID: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MACROBIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  UTI Headache, neck pain, jaw pain, chills and, eventually, heinous hives requiring medical treatment. I started taking Macrobid on Jan 2, 2010 and completed a 7 day course. I was exhausted and had a headache and chills, but attributed it to the infection. I did notice a slight rash on my leg, but didn't attribute to macrobid. Approximately 2 weeks later the infection recurred, I was placed back on Macrobid and took about 5 pills. I had a headache, jaw, ear and neck pain. When I woke up on the 4th day of treatment, I had hives on my legs, arms, back, etc. I stopped the antibiotic, called the nurse took a benadryl. That evening the hives got worse, clinics were closed, I felt exceedingly ill and did not have the energy to do much other than take more benadryl and cover my body w/calamine. By 8am the rash was so bad that I could barely get up. When I got to the walk in clinic, I was short of breath, I had hives LITERALLY from head to toe, chills, etc and was sent to the ER. I was given prednisone and an additional antihistimine. Two days later and I am still on the course of treatment from the ER, I have hives (though they come and go...but not gently), headache, chills, hot skin, neck and ear pain. Upon picking up the first prescription for this, I looked at it and told my boyfriend that it looked like poison. I am only hoping that when the 6 days of steroid treatment ends, I the hives will be gone. It is sheer luck that I didn't take another pill, as I would likely have gone into shock. I will NEVER take this again and would strongly suggest that no one else does. F 41 3 days
1/29/2010
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 3  UTI Nausea pretty severe. Slight swelling. Bloating. I don't think I can take this medication again. The nausea is just too severe. F 40 10 days
1/28/2010
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 1  uti Chills and abdominal pain F 39 5 days
1/28/2010
 5  UTI None I have been put on this for many UTIs and now use it as a preventative after intercourse. I've never had any problems with it. I would advise to take this at least 4 hours away any vitamins or probiotics as that can cause the medication to not work as well or at all. F 22 4 years
1/27/2010
 1  POTENTIAL UTI fever, body aches, chills, stomach cramping, exhaustion I am allergic to Sulfa. I am nursing. I told this to the nurse practitioner and she still prescribed this to me. I don't think the medical profession is aware of these horrible side effects this medication can cause some people. i was on this for 3 days and on the 3rd day the symptoms started. I was put on for a supposed UTI, but results came clean and I stopped macrobid ASAP. I wonder if this is just some new drug that all the sales reps are pusing? Everytime I am at the dr. the pharmacy reps are there hogging their time and making us all wait more and more. I feel much better today, but still not right. I have been drinking as much water as I can stomach in order to flush this out of my system. F 33 3 days
1/26/2010
 1  UTI Severe Nausea,heartburn, indigestion, I thought I was dieing, went to the emergency doctor told me that I had heartburn from the baby growing, I immediatly stopped taking it even though they told me to continue it. DO NOT CONTINUE THIS MEDICINE IF YOU FEEL SICK WEAK NAUSEA HEARTBURN - Go To emergency!! F 18 2 days
1/22/2010
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 4  recurrent UTI I am only on day 3 - experiencing a mild "sour stomach" feeling, abates if I keep my stomach full, and frequent bowel movements. I had a kidney infection last year from undiagnosed UTI,so I take antibiotics at the first signs. Cipro has been good for me, but my doctor doesn't want me to become resistant as there aren't stronger antibiotics. Started Macrobid for the first time, twice daily x 7 days. So far only mild effects as I described. Maybe a mild depressed mood, but can't definitely attribute it to the antibiotic. The UTI symptoms are diminishing. The website is scary though. F 58 3 days
1/21/2010
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 1  UTI prophylaxis I am the nurse practitioner who posted below, this is an addendum to previous post....by the end of the week I saw my primary doctor again and at that point all my liver functions were elevated. It took over a week of being off the medicine for them to normalize. On the 8th and last day I took this medicine, I developed a rash and had extreme painful swelling of my hands and feet which took days to resolve. I had to reschedule my tests with the urologist due to my "fever of unknown origin" and before I had them done this past week, I tried the Macrobid again but after one dose was convinced my experience in December of '09 was due to the medicine. Within a few hours of taking one pill, I developed chills and again for 3 nights had painful swelling of my hands and feet. Anyone prescribed this medicine should be warned of potential serious and dangerous side effects. F 35 8 days
1/21/2010
 1  UTI Extreme chills, muscle pain everywhere(but esp lower back), extreme lethargy, migraine-like headache, minor cough, shortness of breath when walking, and now severe joint stiffness Several UTI's but have never been this ill with a drug before. Assumed I had H1N1 in addition to bladder infection. Finally, on the 6th day, went to emerg because of the severe chills, then profuse sweating, back pain, and malaise because I thought perhaps it had spread to my kidneys, or worse. Urine was clean. I was apparently wasting the doctor's time. Told me to go home and finish the Macrodbid (only 2 pills left) and that I likely had the flu. This is day 2 off the drug. Headache is still there but much better. However, my joints are extremely swollen and I can't make it up and down the stairs in the morning without heavily relying on the wall and railing. My finger joints and even toes are swollen and stiff. I am so sick of feeling this way. I am - correction, was - a fit 50 year old who was supposed to meet at the fitness club tonight to start a new regime. Need this to stop. Wonder if you can OD on prolonged use of Advil? F 50 7 days
1/20/2010
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 1  UTI prophylaxis I am a healthy 35 year old nurse practitioner who has never had any medical problems nor problems with any medication in the past. This drug took 8 days of my life from me. I had about 4-5 UTIs in 2009, which I had never had before, so I decided to see a urologist about them. He wanted to do some tests and put me on the macrobid as prophylaxis until I had them done. Once I started the macrobid, I initially began experiencing muscle aches and fatigue, which progressed into chills and fever up to 103, SEVERE headache, chest tightness like it was hard to take a breath, and a generalized anxious feeling. By day 4 I saw my primary doctor, who I had never seen for anything other than a physical before, and she told me I most likely had a viral syndrome. Through her and the office I work at, during that week I had negative mono, flu, epstein-barr, even parvovirus tests done, a negative chest x-ray, and normal CBCs. But by the end of the week when I went back to see my primary doctor, a My primary doctor agreed, but when I told the urologist about it, he said he had never had a patient experience anything like that, but at least did point out that any person can have a bad reaction to any medicine at any time. I have seen several patients that can take it no problem, but obviously there is a subset of us who REALLY can't take it and I think prescribers (including myself) ought to be aware of the potential side effects from this medicine. F 35 8 days
1/19/2010
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 1  UTI Joint Swelling beginning in right knee, after 2 days moved to left knee, moved to foot and then shoulder. Excrutiating pain so bad could not walk. I've been to my PCP twice for bloodwork, to an orthopedic, and now a Rhuematologist and more bloodwork. No one knows whats wrong with me. I nearly went to the ER twice because the pain was so severe. I'm still suffering the pains from this drug. I started it on 12/22/09 and stopped taking it on 12/28. I'm wondering if I'll ever feel normal again. Do Not Take this Drug! And shame on the Doctor's for prescribing it! F 45 5.5 days
1/18/2010
 1  UTI I wrote in earlier and wanted people to know the hell I have been through since taking Macrobid. I stopped taking the drug on my own on the 4th day or 7 as I was so freaked out by all the reactions I was having - joint pain, muscle pain etc. 8 days after stopping the medication I was rushed to the hospital with a tight chest, problems breathing,heart palpatations, dizziness, and my head in a fog - I thought I was having a heart attack! I was in the hospital for 1 1/2 days being monitored and I have a heart monitor attached to me now. I have now been experiencing tingling and pressure on my entire face and head, stomach ache, and nausea, dizziness and my head is still very foggy for 2 days, 13 days after stopping this dangerous drug! I beg people not to take Macrobid as I have always been a very healthy person and now I can't believe the illnesses I am experiencing! I have now been off the drug for 13 days and I am severely ill. F 49 4 days
1/17/2010
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 1   Never take this med! This medication is very dangerous. This is apparently a fact that is well known throughout the medical field. One dose can be harmful. I see some people commenting on having no side effects, those people should consider themselves very lucky. It is only a matter of time before it is taken off the market. Meanwhile people are being hurt by this drug. Thank goodness for forums like these, if I hadnt found it we never would have figured out what was wrong with my wife. There are so many other meds that can be used to treat UTI's. why even bother. M 30 1 days
1/7/2010
 5  UTI Drowsiness, and a little gassy. The bladder infection, or UTI, itself is a miserable thing to have. So I can endure the side effects as long as it will cure the infection. I was lucky—the side effects were low. The one I seemed to have was drowsiness, although I can’t tell if its from the medication, or the infection itself. Take this medication with food and if taking it twice a day, be sure to take it like clock work. I felt improvements with my UTI within the second dose. By the time my week was over, and my meds gone, I seemed to be cured if the UTI completely! F 31 7 days
1/5/2010
 5  UTI None I've taken this every time I get a UTI and have never noticed a single side effect. I could easily write horrific reviews about Pennicillin and Sulfa drugs because I'm ALLERGIC to those. It's not the drug or the dr. that's the issue if you're allergic. I've been on this with every UTI. years and years back and am on day 3 of it now. F 36 5 years
1/5/2010
 4  UTI Some minor stomach cramping and diarreah (once per day) which is manageable I took bactrim first for 3 days and it did not resolve the UTI. I am currently on day 3 of macrobid and other than the minor side effects I have listed the drug seems to be working. I am not completely well yet but do think that by the end of my prescription (10 days) that it will be gone. F 46 3 days
1/5/2010
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 1  suspected uti but didn't have one In March 2006, I was prescribed Macrobid. I was 40 yrs old, athletic, never sick in my life, non-smoker, drinker or drug user. I was given 14 pills. On the 1st pill I got a racy head and felt totally buzzed, and got a hive on my hand. Silly me I continued to take them. On the 4th pill I couldn't even walk up a flight of stairs I had what felt like water on my lungs. I had pain behind my eyes. Pains in my arms. Sick to my stomach. I stopped the meds completely, which in turn, resulted in hundreds of hives from head to foot. My lips were cracked, larengytis, couldn't walk from one room to the other without being out of breath. I was at the ER about 15x in the course of a few months. My blood cell count was so elevated meaning my body was fighting something that was invading my ammune system. I had a period where my head was so painful I thought it was going to explode. I couldn't touch my chin to my chest I was frozen stuck and stiff. My entire tongue, left side of my face and left big I have had friends use this medication with no side effects. You couldn't give me a million dollars to ever take one pill again as long as I live on the face of this earth. F 44 4 days
1/2/2010
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 1  UTI Dizziness, Joint pains, muscles tickled, foggy, gas, inability to focus, bloating, nausea, shortness of breath, anxious feeling. This is my first UTI infection. I informed the doctor I am allergic to penicillin and septra drugs. I am on day 3 of taking Macrobid of a 7 day prescription. After day 2 I went from urinating 7 times overnight to 4 times, but I started feeling joint pain, tickling of the muscles in my arms, legs, and hands and a stomach ache. I called Telehealth Ontario and spoke to a registered nurse after checking this website since I think I may be having an allergic reaction and I'm not thrilled about being on Macrobid. She suggested I take the next pill since I can't see the doctor until tomorrow and then decide after consulting with my doctor. I very rarely get ill, so this is very disturbing for me and I'm just hoping I can be switched to another antibiotic. F 49 3 days
1/2/2010
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 1  UTI Nausea, dizziness, hot feeling in face and hands, sore throat, spacing out, stomach cramps, fatigue, heartburn I was prescribed this for a UTI by an ER physician. I took the first pill today and never have I felt more sick in my life!! I feel "high" and sick at the same time. This is the most awful medicine. I certainly will not continue to take this medicine. I am going to ask my Doctor for something else. F 26 1 days
1/2/2010
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 1  UTI Almost 4 years after taking five MacroBid pills over a 2.5 day period, I still experience the pain of severe nerve damage. The pain is mostly in my arms and hands, but when I have a flare-up, the pain is everywhere. MacroBid was poison to my system and has negatively impacted my quality of life. Stay away from MacroBid. The FDA should remove it from the market, and doctors should be made aware of its impact on many people. F 68 2.5 days
12/31/2009

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