MACROBID Reviews (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE)

Average Rating: 1.7 (1815 Ratings)

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 ANTISEPTICS,URINARY TRACT

 Type: Rx Drug

  

MACROBID  (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE):  This medication is an antibiotic used to treat bladder infections (acute cystitis). It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. This medication should not be used in infants younger than 1 month old (see also Precautions section). This drug should not be used to treat infections outside the bladder (e.g., kidney infections such as pyelonephritis or perinephric abscesses).   FDA Approval Date: 1991-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MACROBID: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MACROBIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  UTI I have taken macrobid since I was 17 for UTI's and Kidney Infections and never had an allergic reaction until this last time. I took my 1st dose of Macrobid for a UTI on Monday night at 9:00pm with food, and woke up at 1:30 am with this pain in my chest, I thought it was heart burn so I took two antacids then went in to the washroom and noticed that my face was swollen, as were my hands, feet and Lips, and my whole body was red and felt like it was on fire. I walked in to my living room and started to have trouble breathing, Had to call an ambulance and was treated with Benadryl, Gravol, and ultimately a shot of Epinfrine. I will never take this medication again, and I feel scared to take anything else after my severe adverse reaction. I feel like they have changed the drug, as I never had any adverse reactions to this before this and I haven't taken Macrobid in over a year. If you get perscribed this medication please do not take it, or ask for something else. F 34 1 days
100MG 2X day
1/26/2011
 3  UTI I feel swelled and itchy and have dry skin from head to toe. I am dizzy and numb in my feet and hands. I feel nausea and have headaches. Sometimes all at once. The dizziness comes and goes same with the numb feet and hands. Also have a black tongue. Now on day 7 and STILL have a slight feeling like I have to pee once in a while so is this really helping? This drug scares me. I have UTIs all the time and swear I know more of how to prevent them than the doctors do since I've had them for 30 years and have done a lot of research on them. My UTIs are VERY hard on my body, blood, horrible urgency and pain, severe diarrhea too so I MUST take something for them. I was on Norfloxacin but my body is now immune to that drug. F 49 7 days
100 mg 2X day
1/23/2011
 2  UTI Nausea, headaches. My pharmacist said take with food. He wasn't kidding. Nausea is 10x worse if taken without food. This is the 2nd time I've taken this drug for a uti. To me, it's not worth it when other drugs out there are just as effective. It's not worth the constant nausea or persistent headaches. Yes, it did help my uti. Took 2 doses before my discomfort went completely away. Usually 1 does of cipro or bactrim clears it right up. Will never take this again. F 31 2 days
100 mg 2X day
1/21/2011
 1  UTI Severe neck stiffness/fatigue/palpitations It did help my UTI--but the side effects are horrible...palpitations were worse upon any type of movement. Didn't associate any of this until last dose was taken. F 50 3 days
100mg 2X day
1/21/2011
 1  UTI throat, tongue, neck and face swelling. eye swelling, awful rash, shortness of breath. headache..it also made me extremely tired. I felt just short of death! I took this paired with another antibiotic. By the 5th day i could hardly breathe, couldnt even swallow water, couldnt talk because of the facial swelling it was horrible. this medication is a dangerous medication and should be removed from the market. F 29 7 days
100 mg 2X day
1/19/2011
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 1  UTI The first time I took Macrobid, it worked but I was nauseous, sweaty, and had chills and joint pain. But my UTIs kept recurring. I even developed two kidney infections while on Macrobid, which does not work on upper tract infections. Cipro worked both times to cure them. But, I was placed on Macrobid as a 'prophylaptic treatment' to prevent further UTIs, although I am not sure it ever actually helped. I should have listened to my body, and not the doctors, who absolutely denied the drug could cause any side effects. I developed a very severe allergic-like reaction, including hives, vomiting, angioedema (swelling of the hands, face, ears), difficulty breathing, and tachycardia. One year later: I still have eosinophil activation in my gut (confirmed by biopsy), causing vomiting and intense nausea. Heart palpitations still occurring. This is a non-IgE mediated allergic reaction which may have been triggered by Macrobid (there is not, unfortunately, a conclusive diagnostic test for this type of reaction). I am being treated with steroids, and may have to remain on them for the rest of my life. I would advise patients who first experience side-effects of this drug to please listen to their body and discontinue treatment!!! It doesn't work for everybody, and unfortunately, doctors seem to find its strange side effects difficult to accept. I wish I could go back in time and stop myself from taking this drug... the last year has been hell. F 31
2X day
1/18/2011
 1  UTI Took on a Thurday night woke up in the middle of the night with fever, chills, and sever joint pain. Thought I had the flu stayed in bed all weekend Fri - Sun. Felt better on Monday and remembered I didnt take the macrobid thru the weekend so started it back up Monday night and again woke up with the same problem along with a chronic cough and shortness of breath. Relized it might be a side effect of the drug and researched it on the web. It does list those as side effects. Will never take Macrobid again. Had taken it a few months back for my chronic UTI's but had no side effects the first time. F 34 7 days
100 2X day
1/18/2011
 4  UTI turned into Kidney Infection 6 days out of the 12 prescribed. I honestly did not notice any side affects the first few days as I was heavly medicated from the hospital from a drip bag thinking that the vomit feeling I have had/ still get at night was from that. Now apon reading this site. I have noticed alot of the same symptoms. Drinking tons of water still leaves my urine a weird greenish/orange color, at night I feel the need to vomit, and have been going to bed around 6pm waking up at 5 30 am still tired. I have though noticed my kidney's do not hurt, and going to the bathroom feels normal now. Expect that I may have got a yeast infection from all the antiboditic. ( It dose say though on the medical form that itching and white dischage may appear) So I am not fully sure. Just incase i may use monostat tonight.. All in all I will still use to the end of the dosage as it seems to of cleared up the orginal problem. F 23 12 days
100 MG 2X day
1/17/2011
 1  uti Extreme nausea all day starting the 3rd day. Racing heart. Bad taste in mouth. Cotton mouth. Weird feeling in feet. Quit drug and switched. The effects were extreme and terrifying. On the 2nd day, my belly was distended with gas. On the 3rd day, I was hit with a violent wave of nausea. No fever. Full appetite. Just bed-ridden with horrid nausea. Between 3rd and 4th day woke at 4am with my heart racing so wildly that I. Was ready to call 911. Seemed my face and feet and tongue felt weird as well. Bad medicinal taste in mouth. All symptoms went away 96% within 24 hours of quitting this drug. I have never had such a horrible reaction. I literally felt out of control. Now switched to keflex. I found this page after I started to get sick on the macrobid and my doctor thought it was unlikely the drug causing it since it started after the 2nd day. F 37 7 days
2X day
1/17/2011
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 1  UTI I developed a sore throat and terrible cough and tightness in the chest. Very tired. By day 6 i woke up and my chest was so tight I couldn't catch my breath or stop coughing. I stopped taking it and was put on a zpack and within 24 hours the cough is 10x better. Also caused diarrhea and stomach cramps. I will never take this again. F 35 7 days
100 MG 2X day
1/11/2011
 1  Urinary infection Macrobid also known as Nitrofurantoin contributed to development of peripheral neuropathy feet and lower legs. Manifestation presented with night time severe cramping and eventual painful arch tendonitis and compromised and very painful walking. No history of diabetes or other medical contribution for the neuropathy - only Nitrofurantoin prescribed as a prophylactic treatment for chronic bladder infections over an 18 month period. Nitrofurantoin eventually caused permanent disability. Physician beware. Because of the use of the term Macrobid I recently did not pick up the fact this is also Nitrofurantoin and within 48 hours of taking this product I was again experiencing nighttime spasm and painful feet and shin area. It was through my own research that this product is not recommended for everyone and physicians should pay attention when prescribing this drug and hearing patient trying to get help for the neuropathy complaints. F 77 7 days
100 mg 2X day
1/11/2011
 1  bladder infection Do not take this drug. I was rushed to hospital with difficulty breathing and rapid heart beat. Caused a non bacterial pneumonia. Spent two days in the hospital on oxygen, many tests, pulmonary and cardiology. Hoping lung damage is not permament. It has been three weeks and am still fighting side effects. Do not take this medication!!! F 50 3 days
100 mg 1X day
1/10/2011
 1  UTI, I thought nauseated, tired, dizzy, drowsy I never have problems with meds. I am so glad I read your comments before I started taking it. That way, I knew it was the medicine that was causing my symptoms. Before I took the first pill, I called my OB/GYN and was re-assured that this med. is safe and "mild." She said that's why they give it to pregnant women for UTIs. (I called the pharmacist and she said the same thing.) So I felt ok about taking it. (I was concerned with the drowsy warning sticker on the bottle, since I teach. I couldn't afford to be drowsy!) I felt terrible on it and stopped it after 10 days; I just couldn't complete the 14 days. I felt better when I stopped! I never want to take this again...and I won't! F 59 10 days
100mg 2X day
1/8/2011
 4  UTI No side effects on day two. Cipro was ineffective on my bug. Has anyone noticed problems with healing of decubitus ulcers while on Macrobid or the generics? I see studies where some have complained of the problem. M 51 10 days
100mg 2X day
1/4/2011
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 1  UTI I woke up on New Year's Eve with a bad rash all over my body. My face was swollen and I felt very fatigued. On New Year's day I started with severe headaches and that lasted for 3 days. I also experienced gas and bloating. I have never had an allergic reation to any type of medicine or antibiotic. This was my first time on Macrobid. I have advised my doctor and my pharmacist to make sure that I will never be prescribed this again. I have been miserable since New Year's Eve and is worse than the UTI! F 47 2 days
100 MG 2X day
1/4/2011
 2  Urinary Tract Infection I've taken this drug many times throughout the years. This time, OMG! It was the 5th day. I woke up at 6am with hives. Not thinking...I took all my medications along with some Reactine and went on with my day. Oh and yes....I took the Macrobid. Well...by 1pm I was covered in welts on all of my extremities. My vagina, down my legs, under my arms, my bottom, my hands, my feet and my head. My ears began to well huge. I went to the ER. Because I wasn't having difficulty breathing, they gave me a 1/2 dose of prednazone and told me to take Benadryl. The Benadryl didn't do much for me so I took Reactine instead (20mg). ER dr said don't be surprised to see another breakout in 24 hrs. Yes...he was right. I'm now covered and itchy!! I feel like I have the chicken pox. So, bottom line, I won't be taking this again but that's just me and how my body reacted. Allergies can appear out of the blue even when prior you never had them. I did get a numb tongue and lips also but because my F 43 7 days
100 MG 2X day
1/3/2011
 1  UTI Nausea, Dizzines to the point that I fainted, cramps, fatigue, chills, vertigo, headache I was never allergic to any medications, this is the first time I experience something like this. I have been drinking lots of cranberry juice and water and has help with the pain. I called the pharmacy to put an alert in my file and call my doctor to request a change of antibiotic. HORRIBLE! I was sick all the Sunday, it was very scary. This is not a safe medicine to take specially if you are pregnant. NOT RECommended at all..... F 36 1 days
100MG 2X day
1/3/2011
 1  UTI DO NOT TAKE THIS MEDICINE!! Horrible hives 2 days after the last dose- swollen wrists and hands, itchy everywhere, neck, scalp, arms, knees, feet, groin, EVERYWHERE....HORRIBLE...put me on it b/c it is "safe" for pregnancy. I became terrified. Now I am wondering if my baby will even make it... F 32 7 days
110 mg 2X day
12/29/2010
 1  uti Nausea, intestinal cramps, terrible gas, diarrhea, fatigue, headache pretty much non-stop. Feverish, chills, body aches especially in joints, insomnia despite fatigue. Yet another case of cure being worse than disease. Back to doc this am to find out what my other options are, as still have UTI after a week (and Christmas week at that) of feeling awful. Big thumbs down for macrobid!! F 57 7 days
2X day
12/27/2010
 1  UTI I just spent 5 hours in the emergency room with an epinephrine injection and intravenous antihistamines as the result of an allergic reaction to Macrobid. This is the second time on this drug. First time, mild rash that I didn't associate with Macrobid. Second time, this a severe allergic reaction with hives and welts all over my body as well as extreme swelling of my face, hands, feet. Next time the Dr. said it could kill me and gave me epi-pen just in case. Ask for a different antibiotic. There are many others. I don't have any other drug allergies but now I am scared to death that similar symptoms could occur after treating a simple UTI. Be aware, my allergic reaction started 3 days after I had finished the entire course. These symptoms were not present during the dosing week. F 34 7 days
100 2X day
12/21/2010

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