MACROBID Reviews (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE)

Average Rating: 1.7 (1815 Ratings)

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 ANTISEPTICS,URINARY TRACT

 Type: Rx Drug

  

MACROBID  (NITROFURANTOIN; NITROFURANTOIN, MACROCRYSTALLINE):  This medication is an antibiotic used to treat bladder infections (acute cystitis). It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections. This medication should not be used in infants younger than 1 month old (see also Precautions section). This drug should not be used to treat infections outside the bladder (e.g., kidney infections such as pyelonephritis or perinephric abscesses).   FDA Approval Date: 1991-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MACROBID: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MACROBIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  UTI Severe migraine-like headache, nausea, chills, severe neck pain, leg pains, shakiness. Only took 3 doses over 1.5 days. Took as directed with food and full glass of water. Drank lots of water while on medication. Side effects started after first dose -- got very dizzy and drowsy and took a 4 hour nap. Woke up with headache that worsened with each dose. Called doctor and told them about effects and that I stopped taking it. I am calling 1.800.fda.1088 to report my side effects. F 29 1.5 days
9/11/2009
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 1  Bladder Infection Fatigue, an extreme, stabbing headache, blurry vision, balance problems, nausea, chills and sweats (but no fever). The headache trumped any migraine. I only took two doses, contacted my doctor and was instructed to immediately stop taking the medicine. The headache, vision and balance issues lasted for about 24 hours and then went away. I felt like I was going to die. I would never let someone I know take this drug. F 38 1 days
9/11/2009
 1  uti sudden onset severe chills, tremors, fever headache, arthralgia, severe muscle pain, weakness, couldn't walk, thought I would die rushed to Ed by ambulance after apparent vascular collapse. Had nausea vomiting, a real nightmare! I took this Rx had above side effects 4 hours later called MD in a.m. said most likely viral. Stopped taking while sick took 4 days to get over. Started to take again 1 week later, wound up in ED blue nails cold feet hands, SOB unable to walk. Took 4 days to get over. Never take this drug!! F 54 1 days
9/10/2009
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 1  UTI ACUTE LIVER FAILURE! Barely made it before getting a liver transplant. If anyone prescribes this medication to you don't take it. F 64
9/8/2009
 1  long term suppression therapy UTI over 18 months I continued to get worse without any positive bacterial cultures in my urine-but had pain, fatigue, confusion. Finally I collapsed and ended up in emergency with diffuse intersticial lung disease and fulminant hepatic failure. My lungs responded to treatment, but my liver finally was necrotic. I received a liver transplant July 5 2008, spent 2and 1/2 months in the hospital, and will be on immunosuppressants forever. I also have neuorpathy in my right arm, though it seems to be improving. The effect of the drug is insidious-and the symptoms could I think have mimiced a UTI. I saw my GP at least twice a month, and a urologiest 5 times over the course of prescribed treatment. My advice is if you take this drug for more than a month, get frequent blood tests to check for liver function. Be alert to breathing difficulties. F 57 18 months
9/4/2009
 1  UTI Constant nausea, vomiting, chills, dizziness, sweating, severe knee joint pain, fatigue, weakness, unable to eat or keep anything down. Cannot believe that a Dr. would prescribe this medication. My mother had a recent severe illness & got a bladder infection from the catheter. She called Dr. with the symptoms after beginning this drug and he told her it was probably just the flu. She took this for 3 days....hours after first dose she was constantly vomiting, had chills/sweats, couldn't eat, dizziness, felt like she was going to die. It was all she could do to get from bed to bathroom each day. Day 3 afternoon was feeling a little better, until she took her evening dose....it all started back again! I looked up this med online & wish I would have done it earlier. After all she has been through - this was totally unnecessary. F 59 3 days
8/29/2009
 1  UTI Tightness in chest and upper back, chest pain, coldness in lungs & difficulty breathing, extreme fatigue, rapid heart rate, panic attacks, nausea, lack of appetite, unexplained coldness in hands & feet, overall body weakness, pain in hips, wrists, ankles and knees, diarrhea, frequent need to urinate, continued side effects post-medication cessation. I was sick with what I thought was an autoimmune illness for nearly 4 weeks before the nurse practioner who works w/ my dr. ordered a CT scan to see what might be causing my endless nausea and abdominal pain. When I couldn't get in to see her the next day for the results of my test, I went to the ER of the hospital where I had the test. While there, I had a urinalysis and found out that I had a UTI. They gave me 100 mg of Macrobid and a prescription for 14 more pills (100 mg) of the Macrobid generic Nitrofurantoin. I didn't start experiencing the side effects until the next day when I woke up from a nap to extreme panic attack-like symptoms (closed throat, difficulty breathing, RAPID heart rate and chest pain). I was so afraid that I was having a heart attack, that I called 911 and went back to the hospital via ambulance. As I have panic/anxiety disorder, they diagnosed it not as an allergic reaction, but rather a panic attack. The ER called my dr. and he said for me to stay on the drug. During the next four days, I suffered the same side effects around the same time every day, some more than once a day, others continuously. Finally, on the evening of day 4, I paged my dr. at home and he called me and basically felt that it was anxiety-related, despite my talking about all of my other symptoms, none of which I get when I have a panic or an anxiety attack. I took my last pill 48 hours ago and I'm still experiencing most of my side effects, again which are being called anxiety- F 39 7 days
8/27/2009
 4  Bladder Infection Mild stomach ache with ocassional stomach cramps, mild to moderate fatigue. Was prescribed Nitrofurantoin Mono/Mac, the generic form of Macrobid for an acute bladder infection that developed 3 weeks after being operated on for bladder cancer. Also had to have a stint put in my bladder to protect the site where the cancerous tumor was removed during the same surgery. Pain and nausea from the pressure of the stint in my bladder since the surgery 3 weeks ago has been indescribeable and goes well beyond the threshold level of 10 on a 1 to 10 scale for pain & suffering. Have somehow survived it all so far and the stint will finally be surgically removed 5 days from now IF THE MACROBID CLEARS UP THE BLADDER INFECTION IN TIME! So, I'm really counting on the Microbid to do what it is supposed to do...otherwise, surgery to remove the stint will have to be postponed until the bladder infection clears up. My Macrobid dosage is 100 mg twice a day for 10 days. Was previously prescribed Bactrim which resulted in only minimal improvement in clearing up the infection. Have been on the Macrobid approaching 3 days now with 7 more to go before finishing the 20 capsule prescription. At this point, other than experiencing some mild nausea and ocassional stomach cramps for about an hour or so after each dose, haven't had any severe side-effects or adverse reactions to this drug. M 57 3 days
8/26/2009
 1  UTI I was fine for the first day, but on the second day I suddenly developed severe itching and tingling in my hands and feet. We were out to dinner near a bookstore and immediately went to a bookstore to find a Physician's Desk Reference. We looked up Macrobid and found that this was a serious side effect and could lead to permanent nerve damage (peripheral neuropathy), and if it occurs the drug should be discontinued immediately. I did so and contacted my doctor the next morning. Fortunately, the symptom did not persist (well, it did, sort of -- see comment) Ever since taking that Macrobid several years ago, I have had what seems to be a unique symptom in detecting future UTIs. Whenever I get a UTI, my first symptom is a recurrence of that same heavy, tingling, itching feeling in my feet that I got with the Macrobid. Within an hour of that, I will start feeling the other symptoms. So, it DOES seem to be permanent nerve damage, although in my case it's actually proved helpful. Not that I would recommend getting nerve damage for any reason, mind you. F 42 2 days
8/25/2009
 2  UTI I am experiencing fatigue, severe throat tightness, mild tightness in the chest, definitely feeling sort of "disconnected" and oh my gosh these headaches are the worst I've ever had. I've only been on it for 3 days. Should I stop? F 23 10 days
8/24/2009
 1  Urinary tract infection I was supposed to be on it for ten days but on the sixth day I started to have nausea and severe stomach pains and back. I tried it for two additinal days and gave up. It was taking too much out of me and I was very weak, and tired all the time. Had tried Ciproflox and it didn't help,similar symptoms but not as bad as Microbid. I have also tried Sulfatrim. After eight weeks of trying these drugs none has solved the problem. I am a fairly healthy senior, not taking any other medications and no other problems, except a little arthritis F 80 8 days
8/24/2009
 1  chronic UTI i was prescribed macrobid by a urologist to take twic a day for 2 weeks then once a day for two weeks. by the third week I developed severe chills and fever 101 to 103 degrees with complete loss of appetite. I saw my primary physician on the 5th day with fever of 102.8. He did a complete lab, chest xray, and influenza test...all negative. My only other symptoms were shortness of breath and severe fatigue. I stopped the Macrobid and the fever subsided within 2 days. I am certain this was a reaction to this medication. F 57 3 weeks
8/23/2009
 1  UTI Symptoms came on suddenly, 103 fever, nausea, severe headache, light-headed, loss of appetite, tired, head hurts even laying on a pillow, body aches. went to hospital, they thought I might have a virus, but weren't really sure. They never suggested a reaction to this medication. F 49 8 days
8/23/2009
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 1  bladder infection After only two pills I had a fever,chills, aches,pains and cramps in my legs. It was worse than any flu that I have experienced. I could barely walk and I thought I was going to die. This drug is poison and should be off the market! The doctors and nurses at offices give prescriptions not warning people that these drugs have life threatening side effects. M 63 1 days
8/23/2009
 5  UTI loss of appetite, tiredness Was taking this before I found out I needed something else so I was then given Cipro. That was a horrendous story of itself. Macrobid was awesome and the loss of appetite wasn't a bad thing. No other side effects at all other than being tired. Everyone is different so don't take these reviews too personal. F 27 7 days
8/22/2009
 1  UTI rash, intense itching all over, tingling, numbness, chest pains, sore throat, heart burn, stomach upset I went back to my doctor who thinks I have a virus. After reading the other people's symptoms here, which match my experience, I think I've had an allergic reaction to macrobid. Never, ever take this again! F 44 8 days
8/21/2009
 5  UTI prevention no side effects This has been a wonder drug for me, Have been taking macrobid daily for 2 years and have not had a UTI since. F 38 2 days
8/20/2009
 1  UTI developed a rash, lips feel hot and face at times, vulva felt red hot and slight itching on the outside, depressed, tired, low back pain, tightness of the throat and when swollowing, some cramping..rash on my hands..thought they were bug bits at first...symptoms were bad on the 6th day..I know I'm having an allergic reaction..but I only have two more days to go. Just so mad that my obgyn saw me yesterday since i thought i might have had a fungal infection.because of the intense heat in my vaginal area on the outside and burning sensation that lasted one day..now i see its allergic reaction to this drug. This drig should be off the market..my obgyn never asked me if i had any health problems before prescribing this drug to me nor warn me of the side affects as well. I hate this drug..i kept finding myself getting depressed and crying for no reason...now i know its the dumb drug. F 34 7 days
8/18/2009
 1  UTI numbness in areas of arms hands and fingers, joint pain, muscle pain, ligament impairment in arms, weakness of arms, pain in area of gallbladder, breathing problems, anxiety, photosensitivity resulting in burning swollen red skin on arms, racing heart I took this drug for the treatment and prevention of UTI's over a year ago. I experienced severe side effects some of which plague me today. I finally was able to get off antibiotics when i discovered d-mannose. I went from having a severe UTI every week or two to having none at all. D-mannose has prevented me from developing a uti for over one year now. D-mannose is a natural sugar that's even safe for diabetics to take. Please, I don't sell d-mannose, if you are suffering like I was, or know someone who is, visit squidoo.com/d-mannose and read about my personal battle with UTI's and how I finally found safe relief. I hope this reaches you or someone you know in time to help prevent the kind of suffering I went through. F 28 18 months
8/16/2009
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 1  UTI flu like symptons fever, chills, muscle pain everywhere nausea, couldn't eat, slept for hours Won't take again F 49 3 days
8/15/2009

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