ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)Average Rating: 3.3 (1678 Ratings)Filter ResultsCompare ZOLOFT with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 |
More on ZOLOFT: Reviews Summary | FDA Adverse Event Summary
| RATING | REASON | SIDE EFFECTS FOR ZOLOFT | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | Anxiety | Brain zaps, sore bones/joints, major irritability, tightness in chest | I originally started taking 100 mg of this med a few years back due to mild depression. I didn't notice any side affects. However, my doctor increased the dosage to 200 mg/daily. The side effects were severe. I started experiencing brain zaps that I could actually hear. My bones and knee/hip joints were killing me and I was very irritable. Since these effects were nothing less than scary, I started weaning myself completely off. It has been 6 weeks since my last dose and the side effects have not improved. I'm very active for my age. I live in a tri level house and I am pretty hyperactive. I run up and down stairs all day, every day. All of the sudden, the pain in my knee and hip joints was unbearable. I also started experiencing tightness in my chest which took me to emergency. EKG, blood work, chest x-ray were all normal. In my opinion, this drug is poison! I can't believe doctor's prescribe this to anyone! | F | 67 | 3 months 200 mg 1X day | 3/12/2026 | 1 | Depression | Mild tremors in legs after 8 months. Started tests for various things - Parkinson’s etc. all tests negative. Decided to d/c and started to wean off per doctors’ instructions. This did not work. I obsess about trivial things and over react which is not my usual temperament. | I was able to decrease dose to 50 mg. However, I still have days where I get a little ragey and I pop another half to try and control myself. These pills were bad news for me. If I get to the point where I do not need the extra half pill, I may try again to decrease the dosage. | M | 66 | 1 years 100mg 1X day | 11/17/2025 | 1 | Dementia restlessness | My mother has moderate dementia and was really restless. My sister decided to give her this poison with a doctor's prescription and this crap turned her into almost a vegetable for about 2 months. She eventually recovered but it was the worst two months we had. | Do NOT give this to an elderly with dementia. It was BAD!!! | F | 84 | 5 days 10 1X day | 8/4/2025 | 1 | MDD and anxiety | All it ever did was numb me completely. Made me drowsy all the time and unable to function normally. I missed years of being able to relate to my children and feel any sort of joy. | F | 43 | 3 years 25-100mg 1X day | 3/13/2025 | 2 | anxiety | nausea ibs symptoms | F | 76 | 5 days 100 1X day | 8/24/2024 | 2 | Anxiety | Impotence and emotionally flat. | Slight elevation in mood, but not worth the side effects in spite of my very low dose. | M | 53 | 21 days 12.5 1X day | 8/5/2024 | 4 | Anxiety depression | I feel better than I did before starting this antidepressant. The benefits outweigh the occasional side effect of feeling extremely restless. This is the first time I've taken an antidepressant, though I do wish it were more effective. | F | 70 | 26 days 25 mg 1X day | 8/2/2024 | 1 | Agoraphobia | Felt like jumping out of my skin diarrhea heartburn. Shortness of breath. Vision problems l Lightheaded and dizzy Lack of sleep. Even though I was on a small amount | Even though I was on a small amount Apparently I can't take serotonin things worst symptom now, as I feel lMy sinuses are all dried up and I've pain behind my eye. I have tried many of these and think I'll just stay with the anxiety. On zoloft I couldn't function at all | F | 76 | 2 weeks 15 1X day | 7/29/2024 | 2 | Depression / anxiety | After a week or 2 , I had chronic diarrhoea! I felt drained and unwell , loss of appetite . My stomach sounded like a washer machine constantly, not a nice feeling at all. I took Imodium but had no effect . I stopped taking them on my 3rd week after speaking to my gp. But my diarrhoea continues to give me grief. I just hope it stops soon and I get back to normal . This drug done me no favours ! I have gone back on Citalopram . | F | 57 | 3 weeks 50 mg 1X day | 5/12/2024 | 3 | Anxiety and depression | I feel more antsy , nervous, and jumpy on it . I jump easily at loud noises now. More sensitive to noise . I feel kind of like there's a motor going in me . Pulling out my hair much more than usual . | I switched from lexapro 10 mg , because it stopped working as well , and on lexapro 15 mg I was very tired and lackadaisical and I didn't want to leave my bed ; I just wanted to sleep . I'm going to ask my psychiatrist to lower the dose of Zoloft, because it seems to be too stimulating for me . | F | 40 | 4 weeks 100 mg 1X day | 5/10/2024 | 2 | Panic attack | Diarrhea and heartburn and since I have a hiatial hernia it made it worse | Didn't Take it that many days. But couldn't stay with it because of side effects. | F | 76 | 3 days 12mg 1X day | 4/25/2024 | 1 | Anxiety | I'm no longer taking this medication. Now 4 years later... still no improvement with insomnia! The Zoloft caused me permanent damage, it needs to be investigated for its permanent side effects. Doctors have given up and cannot help my insomnia, the damage from zoloft is irreversible and I urge anyone out there to not take this med. | Now over 4 years later and damage from Zoloft has ruined my life. I have not taken zoloft for over 4 years now and I still have this extreme insomnia. I slept great for 35 years until I took this Evil medication, please DO NOT take it! It is not worth the risk! | M | 38 | 25 1X day | 3/12/2024 Patient History | 3 | Depression | Felt like I was on speed and I went manic but with a mood stablizer I'm okay now. That lasted only for a month or two. | Zoloft did not control severe depression. I was cured with antibiotics. However, it helps me as someone with BP to keep a steadier mood. | F | 59 | 15 months 200 mg 1X day | 2/23/2024 | 3 | depression and anxiety | very tired, fed up, burning in back, dizziness, nausea | I started taking 50mg 10 months ago, upped to 100mg after 3 weeks as wasn't doing anything. then upped again to 150mg which I did see a few signs of working. now on 200mg and although have had glimpses of good days I'm starting to wonder if I should try something else. been diagnosed with clinical depression, which I've had for 40 years. if anyone has any similar experience please get in touch. | M | 74 | 200mg 1X day | 10/12/2023 Patient History | 3 | Anxiety and depression | I am still going through these side effects 4 weeks later; Worst anxiety I've ever had Nausia Derealization Upset stomach Jumpy | I really didn't think the side effects could be this bad | F | 73 | 4 weeks 50 mg 1X day | 10/6/2023 | 3 | Anxiety/depression | Lost libido completely. | F | 35 | 3 years 10mg 1X day | 9/29/2023 | 5 | Anxiety and depression | Decreased libido - still present but not an issue. Insomnia to begin with but mirtazapine helps combat this side effect. Nausea and loose stools but changes in diet have helped alleviate some on this. Plus I would rather have side effects than suffer with anxiety/depression. | Wow!!! Wished I'd known about this year's ago as I've always struggled with anxiety which has prevented me from achieving so much from life! Honestly, I have confidence to talk to people now without worrying or working out what they might say or think about me. I am doing things I was never capable of doing and not over thinking about tasks. I can drive on motorways now, in fact I prefer them now. My brain is no longer racing at 100mph. I'm calm, happier and all the things in life that got me worrying and dreading are no longer present. I feel normal, whatever that is :) my wife cannot believe the changes in me, my kids now benefit from me being happier and doing more with them. My work life has improved due to having more confidence and laughing more. It took around 2 months for side effects to subside but well worth sticking with. It also took about two months to fully feel the benefits. Started in 50mg and raised to 100mg after couple of months. Absolutely a life saver for me. I know this won't be the case for everyone as we all have different experiences but for me I would like to stay on it the rest of my life. I take it around 10am after breakfast. | M | 38 | 1 days 100mg 1X day | 6/15/2023 | 2 | depression | drowsiness/low energy, dimmer feelings | it made me super tired, i couldn't make it through a day without taking a nap, this got in the way of my school work and negatively effected my performance. i feel like this just dimmed down my experience of life. i credit my therapist and the changes i made to my own life for my recovery from depression, not zoloft. | F | 22 | 2 years 50 mg 1X day | 4/21/2023 | 4 | Severe anxiety | Had the shakes, nausea and dry mouth at the start. But after a month and put up to 100mg felt fine and more relaxed. Now I have noticed hair loss which is making me more anxious. Anyone else suffering with this? | F | 65 | 6 months 100mg 1X day | 4/16/2023 | 3 | Anxiety and depression | For the past 6 weeks I have been suffering from chronic diarreah so have tapered off the drug. Other distressing side effects include palpitations, sweats, chills, headaches, exacebation of rash, insomnia and vivid dreams. | It did help with my anxiety and depression, but once the dose was put up from 50mg to 100mg per day, the gastric problems started. My GP tapered the dose and I have now been off the drug for 3 days. The gastric problems are slowly getting better but other side effects remain. | F | 62 | 4 months 50mg-100mg 1X day | 3/13/2023 |
ZOLOFT (SERTRALINE HYDROCHLORIDE): Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. (Sources: U.S. Centers for Medicare Services, FDA) FDA Approval Date: 1991-12-30