ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)

Average Rating: 3.3 (1667 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

ZOLOFT  (SERTRALINE HYDROCHLORIDE):  Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.   FDA Approval Date: 1991-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLOFTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  PPD, bipolar II, ADHD-I i responded to the zoloft immediatly - within 24hrs. I was on 50mg and was so "up" i was giddy and excitable. I dropped back down to 25mg and i was fine, very stable until a week ago when i started getting irritable and easily angry. it really made my bipolar worse, not better. however, i am still nursing my son so i cant go onto a different med till i wean him. I havent noticed any weight gain thankfully, my sleeping is fine, but i do have terrible eczema on my face since taking the Zoloft. I was diagnosed with PostPartum Depression. I have bipolar II which of course is why i had the PPD but i was not on any medicatation for the bipolar at all. I was having terrible depressive episodes so when i went to the p-doc they put me on drugs. i was on wellbutrin 100mg originally and it made me have severe mood swings, so they switched me to the Zoloft which was fine for 2 months but now i am expereincing more severe mood swings again. I am also on a whole bunch of Omega3 and b-complex vitamins, my p-doc is thinking he might take me off the Zoloft entirely until i am done nursing so i can go on a mood stabilizer instead of an antidepressant. F 31 2 months
12/16/2008
 5  depression None that I can remember, insomnia at first and a little mania but it worked wonders for me. I was prescribed zoloft 8 years ago for post-partum depression. It worked great for a few years but I wound up on the highest dose and my doctor switched me to paxil. Paxil stopped working for me about 6 months ago and I was started back on zoloft. I love it, I feel so much better. F 27 6 years
12/15/2008
 3  Depression Massive reduction in libido This was a good antidepressant. Took 50mg daily for half a year, really helped with the depression with no drowsiness and a clear mind. The libido thing was pretty bad though, it killed it almost completely, probably due to the serotonin. When i tapered down to 25mg for the 2 weeks before stopping, it came back straight away. M 23 6 months
12/15/2008
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 5  Depression - life-long Headache and insomnia, nightmares when I first started the med. This drug has made a big difference in my life. I suffered for so many years with a depressed feeling -- I did not realize that I had an illness. A lot of people are afraid of SSRI's...that they will change your personality..well, all I can say is Praise God for this medication. I wake up in the morning happy for the day to begin. I started out at 25mg, then 50, 75, and I am now on 100mg. I am now living life as it should be lived. F 50 12 months
12/10/2008
 5  severe depression, anxiety Weight gain, can't lose weight, sleepy This has saved my life literally! I have tried so many anti-depressants and this actually worked! And I could take it while breastfeeding and pregnant F 27 4 years
12/8/2008
 5  Irritable Bowel Syndrome Night sweats My GI doctor prescribed this drug (in conjunction with Seasonique) to help control my irritable bowel symptoms (both diarrhea and constipation with intense cramping which were tied to my hormone levels) and it has worked wonders. I haven't experienced any IBS symptoms with the combination of Zoloft/Seasonique (which I have been on for about 6 months) and had only occasional symptoms when I was on Zoloft alone (for 1.5 years). Before I was put on the meds I lost about 20 pounds due to all of the gastro issues and have since been able to return to a normal weight. The only side effect I have noticed are night sweats. I get them every night (typically a few hours before I get out of bed) and wake up covered in sweat. It can get annoying but I'd much rather deal with sweating excessively than diarrhea. Haven't noticed any difference in my mood since I'm on a low dose (50 mg). F 24 2 years
12/4/2008
 1  depression, anxiety Serotonin Syndrome Zoloft sent me into a manic state and eventually to the ER. Serotonin syndrome is a rare side effect, but it happened to me. This effect took only 1 week. M 8 6 days
12/4/2008
 4  PMS/PMDD WEIGHT GAIN, LOW SEX DRIVE, DRY MOUTH, NIGHT SWEATS, LOSING HAIR, VIVID DREAMS, TROUBLE SLEEPING. ASIDE FROM THE SIDE EFFECTS, ZOLOFT (50 MG) DID MAKE ME INTO A MUCH NICER PERSON. THINGS JUST DID NOT BOTHER ME LIKE THEY USED TO...I LET THINGS SLIDE ALOT MORE AND I WAS MUCH MORE PATIENT WITH MY HUBBY & KIDS (AGE 7 & 4). I COULD LIVE WITH THE SIDE EFFETCS EXCEPT FOR THE WEIGHT GAIN AND SEX, OR LACK OF. I GAINED 8 LBS IN 9 MONTHS AND THEN I STARTED TO FEEL SUPER CRAPPY ABOUT MY CLOTHES FITTING ME TIGHTER AND COMBINE THAT WITH AN ALREADY LOW SEX-DRIVE (FROM THE MEDS), SEX WAS NOT HAPPENNING. I JUST DIDN'T FEEL SEXY ANYMORE WITH THE XTRA LBS. AFTER 9 MONTHS ON THE MEDS, I DIDN'T FEEL LIKE THEY WERE DOING IT FOR ME ANYMORE, SO MY DR. SUGGESTED i INCREASE DOSAGE WHICH I DIDN'T WANT TO DO...I DECIDED TO TAKE A BREAK FROM THE MEDS AND TRY TO DEAL WITH MY SUPER PMS ON MY OWN. WELL, ITS BEEN 2 MONTHS AND THE HORRIBLE PMS IS BACK. I DECIDED TO GET BACK ON MEDS BUT NOT ON ZOLOFT. I AM GOING TO TRY WELLBUTRIN. IT'S SUPPOSSED TO SUPPRESS APETITE AND INCREASE SEX DRIVE. ILL POST F 37 9 months
12/2/2008
 1  social anxiety Worst GI problems of my life- diaharrea, vomiting, intense nausea (and I started at a low dose!) Could only tolerate it for about a week before the GI problems made me dehydrated. Then I tried Celexa with no GI side effects. Unfortunately though, after 5 months, Celexa hasn't worked for my social anxiety at all though. Prozac is next! F 24 7 days
12/2/2008
 5  anxiety at first there was slight dizziness, dry mouth, loss of sex drive, fatigue but these went away after a few months. Now I take 50 mg/day, 100mg when PMS symptoms start and no side effects. This is a medication that pays off if stick through the tough first few months. I have tried several other anti-anxiety medications that either did not help or had unbearable side effects. LexaPro was great, but caused awful migraines, Wellbutrin did nothing for my anxiety, Prozac wiped my sex drive out completely and made me tired all the time. Zoloft has worked well for me for the past 3 years and I wouldn't even consider switching or stopping. F 36 3 years
11/30/2008
 4  Anxiety/Panic Attacks/Depression Loss of sex drive and difficulty in achieving an erection Started at 50mg for 7 days and worked up to 100mg. Zoloft really helps with the anxiety and depression! I no longer have those ridiculous and horrible irrational thoughts of anxiety and feeling dark and down. I'm taking Zoloft with Wellbutrin to combat the loss of sex drive. Don't be afraid of taking anti-depressants like I was. I should have started right when I was feeling those past symptoms. Some individuals claim that anti-depressants cause people to be robots or a vegetable. I'd rather be those than living in hell everyday. Try Zoloft! M 26 10 months
11/28/2008
 1  depression anxiety, fear, loss appetite ssri,s are terrible M 35 1 years
11/26/2008
 3  depression on a 1 to 10 scale mood would stay between 4-6 at all times... no ups or downs just mellow. Gained about 10lbs.... and no sex drive at all on 100mg. Cut back to 50mg and in 2days I had a nonstop boner... no joke. It works but its time to try life again without it.... M 29 1 years
11/21/2008
 4  Panic Attacks, GAD, Phobias Strange sensations during initial week of use which later subsided. Makes me a little sleepy within 30 to 60 min of taking my once daily dose, but not too bad. Zoloft has helped somewhat with my panic disorder, but did not help at all with my phobias. I had to increase my dose all the way to 150mg per day to maintain benefit from taking the drug. I was able to lower it back down to 100mg per day after adding Buspar to my line-up (at 15mg 3 times per day). The Buspar helped me a great deal, and I considered dropping the Zoloft, but my doc thinks the combination of the two is responsible for my improvement so I have maintained the Zoloft at 100mg per day. I would recommend trying Buspar first, and then add the Zoloft if the Buspar is not enough. All in all, I think the Zoloft is helpful... to a degree... but it's definitely not a miracle-drug (at least not for me)... M 33 9 months
11/20/2008
 4  Depression and Anxiety No libido at all, weight gain, not as passionate about things Overall, the benefits of Zoloft outweigh the side effects, since I had anxiety problems (i.e. waking up in the middle of the night worrying about things out of my control, feeling nauseous in public places that were crowded) and severe depression (suicidal ideations, hopelessness, lack of motivation). Zoloft, as well as therapy, has helped me overcome these obstacles. I just wish I hadn't gained so much weight on this medication (30 lbs in 3 years) and that I had a sex drive. My doctor just prescribed me Wellbutrin to combat some of the side effects, specifically the libido issue, so I will see how the combination of the two works. F 33 3 years
11/19/2008
 5  depression anxiety Very sick first day, thought I was going to pass out and was on only 25mgAfter that felt great for 3 months Have raised dosage to 100 mg and feel like myself, No side effects, Regained my appetite. Thank god for this drug M 53 150 days
11/18/2008
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 5  Post Nal Depression, insomnia Shocking nightmares for the first couple of weeks, these then subsided to just bad dreams which continued throughout me taking it. This defintely cured my PND and anxiety. If I had another baby I would take it again if needed. I was also breastfeeding. I was able to sleep again and felt back to my normal self after a couple of months. F 35 6 months
11/17/2008
 4  PTSD, Anxiety Can't sleep at all if I take it at night. if I go to 100mg, severe tremors, worse than albuterol tremors. I started on 50 for a while, and taking it at night was really bad. I didn't get any sleep whatsoever. Falling asleep took hours and if I managed to, I would wake up within the hour for another two hours, so I just took it in the morning. It helped a good deal just being on it with my anxiety and triggers/flashbacks, but it didn't seem like it was working for me as well as it's meant to. 75 didn't help much more than 50 at all, in fact the difference was negligible. My stupid crazy psychiatrist then said oh let's bump you up until you start exhibiting side effects so up to 100 you go! then the shaking started. I would recommend the medicine for someone with PTSD who has problems with anxiety and flashbacks. F 16 3 months
11/17/2008
 4  Depression, anxiety and OCD I would say I felt tired at first, i started taking a low dose and now would like to increase it to 300 mg. If I miss a dose, and I've been on it a year, then I get emotional and upset easily and irritated. I've read the highest dose you can take is 275, so I am wondering if 300 is safe for me to take. I think it is good to try if you have depression, it doesn't help my OCD very much, but it is mild anyway. F 42 1.5 years
11/10/2008
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 3  Depression Sleepy, buzzed, spun out, however I was like that before I started medication, then became more accepting of abuse. Not good. In hindsight, should have kicked out manipulative verbally abusive husband, taken half of his pension, and started a new life, then I would not have needed to take any medication at all!!!! Now he's just an old ugly fart and has made a decision for his family. Was it worth the fight? I'm not sure. F 56 12 months
11/9/2008

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