ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)

Average Rating: 3.3 (1668 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

ZOLOFT  (SERTRALINE HYDROCHLORIDE):  Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.   FDA Approval Date: 1991-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLOFTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Panic Attacks Experienced approximately 39 side effects with this drug; everything from nosebleeds to depersonalization to hallucination. Very dangerous drug! F 31 10 days
4/3/2008
 5  anxiety No side effects or anything. Zoloft has worked wonderfully--no issues at all. F 50 1 days
4/2/2008
 4  Anxiety/ Panic Attacks dry mouth (went away), inability to have any orgasm at all (booo!), when I drank alcohol I had major manic episodes where I blacked out after only one drink and became hysterical! The Zoloft helped the panic attacks greatly. I was always in a good mood. I took it at night, as it did make me fall asleep, but was not a problem after a good nights sleep. The inability to have and orgasm for horrible. It was like getting turned on constantly with no release. I was switched to Efexor due to the sexual side effects of Zoloft. Let me tell you, it does nothing for the anxiety but makes the sex the BEST and LONGEST ever! Hmm... not sure which is better? I think I'm going back to Zoloft. F 27 3 months
4/1/2008
 5  depression weight gain! little sex drive. It worked great for the depression, but the weight gain was too much, had to make the unfortuniate decision to go off. F 50 18 months
3/31/2008
 2  Depression major depression, dizzy, slept all the time, lost lots of weight Depression due to getting sober. Doctor reccomended it. I hated it, took myself off of it and started counseling at my church. F 28 7 days
3/28/2008
 1  Depression headache, sweating, night sweats, nightmares, sleepiness, increased appetite, low libido, and suicidal thoughts. I was prescribed Zoloft 25mg daily for seven days and increased to 50mg daily thereafter. I had never, ever, pondered suicide before taking Zoloft. The first two days on Zoloft, I felt, among many other nasty side effects, but this being the most important to stress here, an unnatural drive to harm myself. One can only imagine if I weren't mentally stable enough to talk myself out of committing suicide! Additionally, Zoloft made me feel "dull" and "blah". It numbed my feelings and caused me to sleep a lot - which worsened my depression because I was sleepy all day thus unproductive. I contantly craved junk food, so I think I would've gained a lot of weight. So I only took Zoloft 50mg for one month, and then my doc switched me to Wellbutrin XL 300mg in the morning daily. THANK GOD FOR WELLBUTRIN XL!! No side effects whatsoever! No decreased sexual drive, in fact, an INCREASED sexual drive! (: I have energy and I feel like I'm myself again. Wellbutrin take F 27 1 months
3/28/2008
 5  Depression Takes much longer to reach orgasm - being male, this is a great side effect to have ;-) I'm a stud now! It also appears to have suppressed my apetite and I have lost 20lbs since taking this drug. I'd been trying to lose weight for years without success, so this was another great side effect. This is the first anti-depressant I’ve tried and it worked almost immediately even though the doctor said it would take several weeks to take effect. I started off on 50mg and had a slight improvement. After a month started taking 100mg and had more improvement. This drug has given me my life back – I wish I had been put on it years ago. I used to freak out about the slightest thing, now I don’t care about trivial things and don’t worry about things I used to worry about. I have much more self confidence too. M 47 3 months
3/15/2008
 3  severe depression, anxiety, ED low libido, extreme fatigue, weight gain, suppressed emotions I've been on Zoloft (was 150 then went to 50mg) and Wellbutrin XL 300mg for almost a year and I thought I was doing okay with them. The only side effect that was beneficial was the suppression of my emotions because, well, I don't really feel anything negative (it's hard to feel positive, too, but not quite as difficult). When I started taking Zoloft I wasn't really eating that much, so I initially blamed my weight gain on returning to a normal caloric intake (I gained 15 pounds within a few months of starting Zoloft, but I also began eating a normal caloric intake). I recently discovered I have now gained over 30 pounds since being on Zoloft while exercising and eating a normal, healthy diet (and, the really strange thing is, I wasn't unusually hungry, just eating normally). I never thought Zoloft was the culprit since my psychiatrist, FD, and gyno. insisted that Zoloft was not the cause of my weight gain and still wouldn't have if I hadn't had a reference question about antidepre F 24 1 years
3/13/2008
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 5  Anxiety and OCD This medicine took forever to work....maybe a month and a half. The side effects at first were sleeplessness, fatigue, teeth grinding, no sex drive, hunger, then no appetite. I think I had about all the sideffects. Zoloft really helped me... All I used to plague my mind with anxiety ridden thoughts now my mind is free to think of other things. I haven't had a decent night sleep in more than 5 years due to my anxiety. I would have dreams about my worries making me discussingly tired and anti-social most everyday.Now I sleep and feel refreshed! I never thought medicine could help me, I'm so happy I gave it a try. F 30 2 months
3/12/2008
 3  depression / anxiety severe migraines, extremely low sex drive, mania, excitability, difficulty sleeping, weight gain, rapid thinking i think there are better drugs out there now to treat anxiety and depression, this drug has far too many side effects for anyone to feel comfortable taking it. however, it does make your mood much better. thoughts of suicide decreased. i generally became more optimistic and active. if you can handle the side effects this drug does wonders. i came off this drug successfully 2 years ago. but am now on celexa (which has way less side effects) and clonezipam for panic attacks. in conclusion there are better drugs out there to treat depression. F 22 2 years
3/11/2008
 3  Clinical Depression/Anxiety/PTSD Loss of sex drive, manic episodes, trouble sleeping. Was placed on Zoloft after suicide attempt. Although side effects were minimal, I started having severe manic episodes after a few weeks -- driving 500 miles for no reason, not sleeping for days, etc. Eventually I was taken off Zoloft and placed on Lamictal, which is now slowly reducing my manic episodes. Zoloft helped balance my mood after about a month, but the mania made my life more difficult. F 19 7 weeks
3/9/2008
 5  Severe anxiety Initially, I had sub-Zero sex drive and could not achieve orgasm. This went away after about 5 weeks, and now I have slightly *increased* sex drive. The only bad side effect I have had is a MAJOR weight gain...about 50lbs in 2 years. Losing weight is very difficult, but I guess it's the price I'm paying for feeling much better....when I started Zoloft, I was in the midst of a mental breakdown. My Dr. suggested Wellbutrin, in addition to Zoloft, but the side effects scare me. F 36 2 years
3/1/2008
 5  Anxiety, OCD In the beginning, I felt a little bit of dry mouth, but I'm not really sure what else because I was 15 at the time. Like any antidepressant, you start out slow and then build up your dose as necessary with doctor supervision. This drug has been wonderful for me. It really helps to control the panic attacks and ocd symptoms. I feel no side effects and taking it every day is now completely natural for me. I have also had extensive behavior therapy, so my advice is not to expect a magic bullet! The medicine will help you get to a place where you can make some inroads via therapy, but should not be used on its own as a cure. F 28 13 years
3/1/2008
 3  depression night sweats, bloating, indigestion, teeth grinding (night), drymouth (these side effects may not all be attributed to Zoloft, but it's my best guess) relieved depression; uncertain about long-term effects (i.e. changes in side effects and effectiveness) F 26 4 years
2/27/2008
 5  Depression and anxiety any I had initially went away after a few weeks but the lack of sex drive is why I had to quit taking it. Some mental fogginess in school. I have taken many drugs but Zoloft was the best for me. No weight issues, energy was good, sleep was amazing. Success with these meds truly depends on staying in touch with your physician so they can adjust or change as necessary. This drug works fast and worked great for me! I have been on Prozac (loved it but I got migranes), Effexor, Wellbutrin, Lexapro, and mood stabilizers Depakote and Lamictal. Today I start Celexa since it has less sexual side effects. If I was single, my only choice would be the best for me, Zoloft. F 40 1 years
2/26/2008
 5  panic disorder insomnia, trouble getting out of bed in the morning, some increased anxiety, heartburn (major) only have been on it 4 days, but panic attacks seem to be lessening, will have to wait and see 25 mgs at bedtime F 38 4 days
2/24/2008
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 4  Depression Hot flashes, weight gain, fatigue, loss of sex drive. I have taken in between 50 and 75 grams of the generic Zoloft, sertraline, for the past two years. This drug really has helped me combat my depression in that I have fewer mood swings, am less irritable and don't get upset as easily. I did gain a minimum of 20 lbs when I went on the drug which was NOT good. In the beginning, I also had some hot flashes and also was pretty sleepy, but that has gone away now. I also have decreased sex drive and can't reach orgasm, but I couldn't while I was depressed either. F 19 2 years
2/23/2008
 1  Mild Depression Severe teeth clenching/TMJ which caused excruciating headaches -- clenching came on right after taking the dose and would gradually wear off -- took me three days to figure out the connection, during which I was laying in a darkened room with a migraine. Do NOT take this drug if you have a history of migraines or TMJ -- this was the worst three days of my life till I figured out the connection from Googleing it -- the manufacturer doesn't say anything about this but there are thousands of hits on the topic. F 52 3 days
2/23/2008
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 5  Major Depressive Episode First 2 weeks @ 25 mg--slight diarrhea and queasiness First day @ 50 mg--felt weird: heaviness in head, floaty feeling in legs & arms and spaciness. However, these effects were gone the next day and never returned though I stayed at the 50 mg dose. I do seem to be experiencing difficulty reaching orgasm though, much to my disappointment : ( I was diagnosed with a major depressive episode about a month ago, and my docs and I decided to combine talk therapy with the Zoloft, and I already feel better. Not cured, mind you, but better so far. Rather than crying fits and sleep-deterring anxiety, I smile and actually sleep at night. My appetite has returned and I have energy again, and don't feel nearly as rotten and worthless as I did. I am going to stay at the 50 mg dose for the next month until I talk to my doc again, but hope it will do the trick. I'm also going to continue my therapy as I have some underlying issues that will need addressing. My goal is to spend no more than 60 days on the Zoloft. F 31 3 weeks
2/22/2008
 4  severe depression Hot and tired all the time for first month or so of treatment. Worsening depression and suicidal thoughts, which I'm not sure is drug-related; could have been organic. Deadening of sex drive! It took 2-3 months for me to get used to this medication, but once I was stabilized on it, it was fine. Helped a lot with ruminative thoughts. It really sucked to go off it-- brain zaps, heart palpitations, etc. F 26 8 years
2/15/2008

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