ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)

Average Rating: 3.3 (1667 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

ZOLOFT  (SERTRALINE HYDROCHLORIDE):  Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.   FDA Approval Date: 1991-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLOFTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  depression, anxiety Jaw clenching, insomnia, sexual side effects, upset stomache, yawning, fogginess, muscle twitches. been taking zoloft for about 4 months now. I take 200 milligrams. it also helped my OCD that i didnt realize i even had until i quit doing and thinking obsessively and negatively.I still clench my jaws a bit. yawning went away after about a week. fogginess comes and goes. getting better.sexual side effects abated. lack of desire did not. constant muscle twitches in leg. you get used to it. Attitude wise,. this pill has saved my life and probably my family and my marriage. Did get a spending high and maxed out all of my credit cards. i have always been a penny pincher. so that was odd. Things dont get to me as they used to. i dont worry as much. im quicker to get "over" something. Its a good thing. F 35 4 months
8/29/2006
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 5  depression/ anxiety sexual indifference, dizziness when I miss a dose I have been taking 150 mg of Zoloft for a long time. (10 yrs). About 3 months ago,I began to have symptoms- not so much depression but of mood swings, severe irratibility & anger. I went to my doc & asked to try something new so we tried Cymbalta (made me manic), then Lexapro (made me completely emotionless). I have been on a downward spiral since going off zoloft, to the point that my doc has me on 2-3 mg of Xanax a day. Yesterday, I went in to my doc & said please, please dear God, put me back on Zoloft. If I thought it was bad before, I was SO SO wrong. Doc says that after being on Zoloft for so long, my brain may now have a chemical need for it. Not addiction, just an alteration. At least with Zoloft I can function and take care of my family. F 30 10 years
8/29/2006
 4  Depression/PTSD The biggest side effects would have to be lack of sexual desire, dry mouth, constipation. Zoloft worked wonders for me for my depression & PTSD. Feels like the medicine is not as effective as it was in the beginning. I started on 25 mg and I am now up to 150 mg. My doctor perscribed Wellbutrin XL to try and help combat some of the side effects & to help with a recent onset of depression that the Zoloft did not help with. All in all, I would have to say that I have had a good experience with Zoloft, but I have heard horror stories about trying to come off the drug. I am going to ask my doctor to help decrease the dose because the addition of Wellbutrin XL has increased side effects of both medicines. F 28 11 years
8/21/2006
 1  Depression Destroyed my sexuality, put me into a dream world Terrible drug, I believe it has permanently ruined my sex life. Doctors have no clue as to dangerous and permanent side effects. I took myself off a large dose very quickly in a vain attempt to save a relationship, crashed within 2 weeks. Lucky to be alive today. Do even consider this drug if you enjoy sex. M 50 4 years
8/20/2006
 4  Chronic Depression for most of life Severe insomnia,weight fluctuations. Once you eat a bite, you don't feel full and crave SUGAR. Works for my form of depression, however it has destroyed my sleeping patterns. Dosage of zoloft is 50 to 150 mg range. I started taking AmbienCR to sleep but at 12.5mg it only helped for 4 hours. I asked doctor about supplementing Zoloft with Trazadone(antidepressant) and he agreed. Trazadone puts me to sleep in 20 minutes. There is synergism (works well together) with the two antidepressants. Currently 50mg Zoloft and 125mg Trazadone. Not sure what ratio will work yet but if I can't sleep, I can't function so I will continue to find balance. I researched Zoloft and literature says 50mg is max dosage. Anything over and it does not help(but I see many take it at higher dosage and my psych. doctor typically prescribes at much higher dosages to patients. This worries me. If sleep is still issue over long term I will look into subsituting Zoloft for something else. M 43 7 months
8/19/2006
 4  depression, anxiety At first, sweating, dry mouth & diarhea(sp?). Longer term, inability to achieve orgasm during sex-but i havent told the dr this still--nice to see i'm not alone here. thought it was bcp, but after getting off them, no improvement. i really wonder why zoloft has this effect. what is it shutting off in my brain?? Zoloft helped me stop crying all the time and get out of bed in the morning & find a more even balance in life-i no longer was sweating the small stuff. Ive varied my dosage, from a high of 200 to a low, now of 25. i am trying to wean myself off, i know it will take time, becuz experiences from missing a dose =weird bad day. So i've been going down in 25 mg increments each month. i'm leaving the country for research for a year and fear i may not be able to obtain a reliable supply, so better get prepared. But ultimately, zoloft helped me. i just prefer to be medicine free if possible, and for pregnancy, etc. i just hope i can do it. F 32 4 years
8/19/2006
 5  Anxiety, Panic Attacks At first, headache, heartburn. Sexual desire is down but sexual feelings are better! I have been on Zoloft almost 4 months now. I started on 25 mg then went to 50 and now I am on 75. I think I have found my dose. I have been on this dose for 3 weeks and now feel so happy..sometimes so happy I can't stand it lol. I also have started taking vitamins and eating better so that might be helping also. I still have a little anxiety, but it only happens when I am tired in the evenings after I have worked a long day. I love the medicine! F 32 3 months
8/17/2006
 1  Depression/Anxiety Excessive sweating, nervousness, sick stomach, zombie-like feeling, tiredness, etc... I would not recommend this drug to anyone, it is not worth the hell you go through, due to the side effects. I had to stop taking it. F 30 4 days
8/13/2006
 5  OCD/Panic Disorder None I have been on Zoloft all of my life. I went through a small phase where I stopped taking it, b/c I wanted to be "free of it". The panic attacks/OCD were so intense, I have never gone off of it again. I started taking it when I was 8 for severe OCD. The dose started at 100mg, in 14 years I am now up to 175lbs. I'm a healthy active indivigual, I'm not over weight, I dont get headaches, and my sex drive is FINE! I wonder how many of these symptons are mental because i've been on it forever and do not have one of these problems. Its worth considering that people with OCD/anxiety/stress tend to examine themselves more closely and therefore notice things that a typical person would not. I love Zoloft. Literally, love it. I'm the Pfizer poster child. I have graduated college and am heading into law school, im a totally normal functioning person. This medicine will help you. If you notice most of the low ratings are from people who only took it for a day or 2 weeks. Well the medicin F 22 14 years
8/10/2006
 5  OCD/Panic Disorder Minor arm tremors, occasional sudden night awakening, decreased libido, bizarre euphoria on third day, vivid dreams This is a wonderful drug. I was an Obsessive-Compulsive hypochondriac who would have several major panic attacks per day over certain worries. This drug has helped me feel like myself again. M 18 2 weeks
8/10/2006
 4  clinical depression with anxiety Initially, some insomnia which subsided. Long term: low libido, fatigue. I currently take 200mg. Zoloft has made all the difference in my life: I'm no longer depressed. The anxiety I experience is somewhat resistant, however, and Zoloft isn't really helping. My doctor has prescribed a very low dose of Seroquel (off-label) to help the anxiety, but I haven't taken it. Its an antipsychotic with lots of serious side effects (I'm not psychotic). So, I may need to try a different SSRI to see if it will help with the anxiety. F 39 9 years
8/9/2006
 4  Depression / Anxiety Diarreah, Upset stomach, tired, trouble sleeping. I guess its working, feel better than I did, but the dirreah is getting old real fast. Its not everyday though just about every 2-3 days. hope it gose away soon, but all in all Id say its doing the trick. M 27 2 weeks
8/8/2006
 5  mild social anxiety/depression For the first couple weeks I was very tired, felt lethargic at times and more anxious at others. I also had an irrational fear that this drug was going to cause me to 'lose my mind' or have some other horrible side effect that SOOO many people write about on-line. I stuck with it, and I am very glad I did. It has been 4.5 months and have had no adverse side effects from Zoloft. I am only on 25 mgs, but I feel it is working for me. I have way more energy, actually crave social situations, when before I preferred solitude, I have a sex drive, and more confidence. The difference was very subtle, but remarkably and slowly life-changing. I am still me. I still feel, my emotions are not numb (thank God), but I no longer internalize, and foster negative feelings. In addition, I am more able to cope with life's blows without sinking into the abyss. As I've already noted, Zoloft is working very well for me. 4.5 months ago when I was researching Zoloft on-line, it seemed that the only people who wrote comments about Zoloft were those with horrible experiences, or had some other negative thing to say about it. Needless to say I was discouraged, very fearful and skeptical to try Zoloft for my first time. I felt I was relatively normal, with just mild depression and anxiety, I certainly did not want to make my situation WORSE! Well I am happy I stuck it out for the initial two weeks (you'll make it through too), because now I feel like myself, only fine-tuned. I promised myself that IF Zoloft worked for me, I would come back and write my experience here. Keep in mind...it is alot easier for anxious/depressed people, like most of us on this sight are/were to some degree, to report negative feedback. People who the drug is working for (like myself), would rather be out enjoying our lives than on the computer writing about Zoloft. But I F 34 4.5 months
8/7/2006
 1  Anxiety/Panic Disorder Complete loss of appetite. Depression. Suicidal thoughts. Increased Sex Drive. This drug turned out to be a disaster. After only a few weeks I didn't eat, had no emotion whatsoever, was more compulsive than usual and had an almost unbearable increase in sex drive- meaning thats all I thought about. It actually made me depressed, which had never been a real problem for me. I eventually attempted suicide after one heated conversation I had with a friend, and because my boyfriend hadn't called that night. I wouldn't suggest it for adolescent depression. F 26 4 weeks
8/3/2006
 5  medium depression, obsessions Sweating, feeling stoned, insomnia, lost appetite and sex-drive, unable to achieve orgasm, all these effects disappeared after 2-3 weeks Love it! Misty depression disappeared, and felt like the turbo in my brain finally stopped. Back to being ME again, even better than in years, more focussed and calm without feeling sedated or anything. Had trouble sleeping but wasn't tired, changed to taking it in the morning, now better. My normally healthy sex-drive disappeared, that worried me, but I started taking Maca-supplements and now its even better! Great orgasms... Frankly, I believe it might even be a bit of a placebo effect, meaning that if you're really motivated to let go of your depression and anxiety, and stop obsessing about yourself (and the side-effects), it will work great for you, as will any pill provided... F 42 3 months
8/1/2006
 5  Depression, Anxiety, Social Phobia Light Headedness, Loss of Appetite, Sleeplessness, Dizzy feeling I have only been on Zoloft for 2 days and I notice slight changes. I am more social and have a more positive attitude towards life. I can finally be me. My only worry is about weight gain. M 18 2 days
8/1/2006
 2  depression loss of libido, insomnia, emotionally flat waste of 6 months of my life M 19 7 months
7/31/2006
 4  Depression/Social Anxiety Insomnia, restlessness, decreased appetite Initially, Zoloft was like my magic pill. It dramatically increased my mood, gave me energy, and just generally relieved the depression in general (I've been on Paxil in the past which was greatly ineffective). However, I took a long break from the medication and when I returned I found it increasing my anxiety and causing a lot of tension and nervous energy. But, it is more than possible that I increased my dosage too quickly the second time. Overall, I found this to be an excellent drug for both depression and anxiety. It made me feel much more self-confident and reduced social tension to a more manageable level. F 21 1 years
7/29/2006
 3  Severe depression, panic attacks Still get depressed and panicky even though I take 200 mg a day and 1.5 mg of Klonopin. F 19 4 years
7/29/2006
 2  anxiety psychosis couldn't sleep for 3 days (after 2 doses), mania, then depression, suicidal voices in head M 16 2 days
7/26/2006

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