ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)

Average Rating: 3.3 (1667 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

ZOLOFT  (SERTRALINE HYDROCHLORIDE):  Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.   FDA Approval Date: 1991-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLOFTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  depression My insurance switched me to generic sertraline when it came out, and I'm usually a big fan of saving money, but that pill was NOT THE SAME -- it dissolves way to easily (in my mouth, before I even swallow it), burns my esophagus unless I take it with dairy, and most importantly, DO NOT BREAK IT IN 1/2 ! When my dose got lowered I tried taking 1/2 of a 100 mg pill, but it is impossible to swallow, dissolves even faster (in the mouth before you can swallow it), tastes nasty, and burns like you're swallowing lye. I previously took the brand-name product from Pfizer, and it worked great - even helped my constipation, and my libido has been better than ever (since I'm no longer depressed). F 35 2 years
7/9/2007
 2  depression, nervous breakdown loose teeth (!) and zero sex drive I took for almost a year - and it did help "even me out" when it came to my mental state. HOWEVER- all of my teeth became loose and would "pop and crackle" when I bit down, kind of like cracking one's knuckles. Dr. said that was not a side effect but I finally did find an obscure mention on a web site that this was a very rare side effect. Was VERY annoying and my teeth actually became loose enough to wiggle some of them with a finger. Weened off as soon as i could because this became rather distressing! M 47 1 years
7/9/2007
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 3  Depression and anxiety Sweatiness, loss of libido, difficulty in orgasm, EXTREME headaches if forget to take drug. Zoloft certainly got rid of my depression and anxiety. It also helped me with sleeping and I did not gain any weight like others have. However I was younger when I tried this so perhaps my metabolism worked differently then. It was impossible to reach orgasm on this drug so I would sometimes delay taking my drug to give my body a mini wash out period and this helped. However, if I waited too long to take the tablet, I endured severe headaches and had to lie down. Fortunately, this was reversible as soon as I took the drug again. I eventually tapered off this drug thanks to my doctor's plan which worked perfectly. The main reason I gave up Zoloft is because at the time there were reports saying that long term use of it was dangerous. M 40 2 years
7/6/2007
 1  Postpartum depression Weight loss, upset stomach This med did clear up the PPD, but weaning off of it has been absolute HELL. I got/am still getting the "zaps" that so many others talk about. Had I known it would be like this, I would have requested a different med. I will NEVER take this med again under any circumstances! M 35 7 months
6/29/2007
 5  depression loss of sexual desire and anorgasmia; difficulty maintaining a quality diet; difficulty getting up in the morning My experience is that there is a minimal dose required to be effective, and that there is a maximum dose above which the effectiveness wears off. At the proper dose, the effect is darned near magic. Whoever said that the generic is not as good as the real Zoloft is exactly right. There is a profound difference, and it's not made up by increasing the dose. The drug acts very quickly, and the loss of sexual desire is almost immediate. I haven't gained weight yet, but I can see how it would be possible. I have a yearning for donuts and recommend an aggressive program. Also, the combination with alcohol is seductive...watch out. M 57 3 months
6/28/2007
 4  anxiety & depression vaginal dryness, decreased libido I've been taking it for 12 years for suicidal depression. This drug has worked really well for my depression, and I feel is worth the side effects. F 26
6/28/2007
 3  Major Depressive Disorder, anxiety Slight dizziness and nausea that went away after the first week, yawning all the time, feeling spaced-out, disconnected, and sedated, complete loss of sex drive, loss of appetite for the first few weeks Zoloft worked somewhat, it helped my anxiety and stress a whole lot, but as for the depression, I think it lessened it but did not relieve it completely. The major problems for me were the complete loss of sex drive and the sedation. I was not even vaguely interested in sex, nothing aroused me at all. And I always felt out of it, very sleepy and not able to concentrate very well. But it did improve my mood and I wasn't so hard on myself. I'm now switching to Wellbutrin XL because of the sexual side effects and sleepiness, hopefully if those are gone I'll be able to get back to normal. I was afraid of Zoloft because of all the weight gaining stories, but I haven't gained a pound. (Initially I lost a couple lbs due to the loss of appetite, but gained it back after a few months) F 25 6 months
6/27/2007
 5  post partum depression Mild malaise, apathy. Didn't really notice the side effects until after I had stopped taking Zoloft and was back to my normal self. Took 50mg every morning. Benefets greatly outweighed the side effects. It did take about two weeks to see any progress, but was well worth the wait. I went from not being able to function at all day to day (think: would not get out of bed) to being able to get through the day like normal. Was very easy to wean. Went from 50mg to 25mg for about a week, then was able to take nothing with no adverse effects. If I ever experience PPD again, I will go straight to the doctor and request this medication again. F 23 8 months
6/25/2007
 5  PANIC ATTACKS,GENERAL ANXIETY,WORRY WEIGHT GAIN,(OFTEN HUNGRY),LOSS OF INTEREST IN SEX, LACK OF ENERGY! I WANTED TO BE THE 'POSTER CHILD' FOR ZOLOFT, IT TURNED MY LIFE AROUND FOR THE BETTER. MY PANIC ATTACKS WERE SO BAD THAT I WAS AFRAID TO LEAVE MY HOME FOR FEAR OF HAVING A PANIC ATTACK (AGORAFOBIA).IT MADE ME FEEL TOTALLY NORMAL,I COULD ENJOY MY LIFE AGAIN, NOT BE AFRAID OF LIFE.IT CURED A LUMP IN MY THROAT FROM ANXIETY, WHICH MADE IT HARD TO SWALLOW CAUSING A LOT OF WEIGHT LOSS. NOW I'M FAT AND HAPPY.WANT TO GET OFF MEDICATION BECAUSE OF WEIGHT GAIN,AND LACK OF ENERGY,(I NAP EVERY DAY W/ MY TODDLER),AND HAVE TRIED BUT I AM A RAGING *ITCH WHEN I'VE TRIED TO GO OFF...THIS IS A CATCH 22.BUT I WAS FEELING SO BAD WHEN I STARTED ZOLOFT, AND IT WORKED REALLY WELL FOR ME IN A DESPERATE TIME IN MY LIFE. BUT I GUESS THERE IS NO MAGIC PILL. DARN! F 38 12 years
6/23/2007
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 4  Depression Decreased libido - works great on my depression. F 40 3 years
6/22/2007
 1  Anxiety/Depression Yawning. Yawning. Yawning. Loss of appetite, weight and desire for sex. Tired all the time. Spaced out feeling. Felt more depressed. I want to take back my earlier rating of 3 on 6/3/07 and now give this a 1 because of the "discontinuation syndrome". This withdrawal is a kicking my ass. I am constantly tired and everytime I move my eyes from side to side there is a sort of jolt throughout my body. It's horrible. Also I get extremely angry at minor things and start to ruminate over said minor things. I don't know how long this is going to last but I will be very happy once it's over. I really believe that SSRI's are evil. The only good that came out of using this drug has been that my anxiety went away and on the second day of using it the pain I had in my joints went completely away. Even that is not worth the mental pain I'm going through now. I am really disgusted with this drug. M 36 7 weeks
6/14/2007
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 3  fatigue, irritability Sleepiness, didn't help with irritability, helped somewhat with energy. I had taken Zoloft initially for chronic fatigue and irritability. For about 1 year it worked well with taking the edge off the irritability, but didn't do a lot as far as giving me energy. So I switched to Effexor, which helped with energy, but didn't help with the irritability. So I went back on the Zoloft since it helped with mood, but this time it made me very sleepy! I had a hard time focusing and wasn't being productive at all. My ob/gyn suggested Wellbutin, which I tried for 1 week and by day 6 and 7, I laid in bed all night, my heart beating fast, my mind racing, feeling very anxious and panicky. I simply could not tolerate this drug!! F 43 5 months
6/13/2007
 4  anxiety, irritability Diarhea, Insomnia, mild euphoria at times, very anxious for first few days Side effects are calming down after 4 days, the side effects havn't been too bad. My anxiety has been like a roller coaster but I am sure once the drug kicks in it will calm down. M 20 5 days
6/12/2007
 1  depression, anxiety weight gain, loss of libido I took Zoloft for 3 months... within those 3 months I gained 30 pounds, without changing my eating and exercise habits. After 30 pounds, I was through with the zoloft. F 24 3 months
6/9/2007
 3  ocd,depression,anxiety dry mouth, increased sweating, sexual problems (libido and ability) I was taking 200mg every morning, however I now only take 50mg as I am trying to get my sexual problems to improve. In addition, I am taking 300mg of wellbutrin, soon 450mg, and I am feeling sexual again. It has also helped me out of a deep depression that zoloft could not do. I love the extra energy! I also take klonopin 1mg 3 times daily. M 36 6 months
6/6/2007
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 3  Anxiety/Depression Yawning. Yawning. Yawning. Loss of appetite, weight and desire for sex. Tired all the time. Spaced out feeling. Felt more depressed. Although this medicine took away my panic it also took away my energy and feelings. I literally felt like there was an impenetrable force around me that nothing could get through. Nothing made me anxious. Nothing made me laugh. Just flat, dull responses to life in general. This was not a good feeling for me. I like having energy. It made me lose weight which is not good for me since I'm naturally thin. I had no motivation on it to do anything. I'd even stopped going to the gym which was something I hadn't stopped doing in years. I asked my psychiatrist specifically for Wellbutrin because of its low sexual side effects and high energy level it's supposed to bring. I'm now on day three of Wellbutrin. M 36 6 weeks
6/3/2007
 2   didnt help me at all i did is cry on this med F 42
5/30/2007
 5  Depression, Anxiety, Disorientation The first week or so I felt a little weird but once the medication kicked in, it was great. I have been on Zoloft for three years(25mg). This medication saved my life. I was very depressed and felt as if I was always disoriented. I wasn't able to sleep at night because I always felt like I was going crazy. I realized I had a chemical inbalance and once zoloft began working for me I was able to get a full nights sleep without waking up feeling like I was spinning or experiencing some kind of psychosis. I wanted to end my life and zoloft really has helped me kick the depression and suicidal thoughts. I take the brand medication zoloft, not the generic. This medication works wonderful for me. You have to sometimes try a few before you find the right one. F 33 3 years
5/26/2007
 3  Anxiety, Depression No side effects I've been taking 50 mg for two weeks and do not notice any side effects but also do not notice any change in my anxiety/depression either. Like taking a placebo right now. F 29 2 weeks
5/25/2007
 1  not really sure... PSSD, low sex drive. it has awful long term side effects (5+ years) F 21 3 years
5/25/2007

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