ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)

Average Rating: 3.3 (1667 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

ZOLOFT  (SERTRALINE HYDROCHLORIDE):  Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.   FDA Approval Date: 1991-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLOFTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Depression First 3 months had "tremors" in my hands during the night, which went away. Ongoing side effects include sleepiness, intense dreaming (take in the morning to avoid this), inhibited sexual response (I'm female, it's like hitting a wall right before the finish line), night sweats and sometimes "hot flashes" during the day. The libido problem actually improved my sex life with my husband by forcing us to be more creative and take more time with foreplay. DO NOT go off this med cold-turkey. If I do it, within 48 hours I'm paranoid and homicidal/suicidal. DO NOT drive a car during a withdrawal - impulses to intentionally wreck the car are very strong. I become certain I'm being followed/watched. This med has given me my life back. I've been taking it for about 10 years now, and my irritability, anger, headaches are all gone. I'm more relaxed and have an upbeat outlook on life. It was as if a veil were removed from my eyes and colors in the world got brighter. F 36 10 years
12/10/2007
 4   F
12/6/2007
 4  Bipolar II/Panic Disorder I currently take 100mgs, but at one time I was boosted up to 200mg which caused two days of seizures. The only side effect that really bothers me is the nausea. F 41 2 years
12/5/2007
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 5  Major Depression Mostly sexual side effects (ED). Alternately sleepiness/sleeplessness. Lethargy. I have to agree that this drug was the godsend for me. Along with therapy, this helped me through the most difficult parts of my life so far, and I wish I had started it years ago. I'm gearing up for a switch to Cymbalta because the lethargy has been increasing for a year or so. Although, I have to say, after reading this site's ratings on Cymbalta, I'm a bit afraid! But after 3+ years on Zoloft @ 200 mg/day, I still think it's time for a change. M 43 3 years
12/3/2007
 3  depression YAWNING, like uncontrollably, really vivid dreams, NO sex drive, inability to orgasim, trouble sleeping, and WEIGHT GAIN! I took this medication for about 5 weeks and gained 10 lbs with no diet change. The yawning was horrible, and felt euphoric. Almost felt high when on this drug. Also, had trouble sleeping and no sex drive, whatsoever. Switched to Effexor XR and it seems to be working so far. F 22 5 weeks
11/28/2007
 4  depression - ocd No specific side effects - just that it stops working over time no matter the dose. Over time - sweet zoloft just losses her spunk. Over 9 years of taking zoloft it works like a champ for awhile.. then drops you like a bad date. So you shop around for another drug dejour - and lose your mind. After a year or so you come back to zoloft and it works again. You can up the amount you take but eventually its a divorce. 300 mg daily wont even put a smile on your face once she has left the building for good. F 35 9 years
11/27/2007
 3  bi polar Loss of sex drive,electrical like brain zaps going off in my head feeling like Frankenstein, diarrhea and the worst effect of all, grinding my two front teeth down to nubbins at night in my sleep in the course of being on it for ten years. Had to get constructive surgery on my two front teeth that got ground down to nubbins due to this drug and grinding my teeth in my sleep at night. Got off this drug recently and glad I did. Still haven't gotten my sex drive back after three months of being off of it. F 52 10 years
11/18/2007
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 2  Depression worked like a low dose of extacy for about 1 mo, then became complacent. No feelings at all, happy sad, nothing. then went suicidal. I stoped cold turkey after taking 150 ml 5 days later ended up in the ER for a suicide attempt, next day, paramedics at my house for talking suicidal thoughts, 7th day tried again spent 2 1/2 weeks in phych word. I couldn't even remember acting this way. I'm now back on it and "stable" , but planning to wean slowly very slowly off it, take coution when weaning, start only as a last resault IMO, herbals, exersize and therapy, spiritual or other wise, anything but a drug as ADDICTIVE gravely so as this type. Yea, don't talk to me about so called addictive medicationsie opiates or benzos.... I never tried to kill myself coming off those.... and never went insain either. feel free to contact me I'm a research junky when it comes to meds! I've got more to talk about! F 33 1 years
11/13/2007
 3  Depression/anxiety weight gain, extreme spaciness and forgetfulness, loss of vocabulary, lethargic, cloudy head, lack of concentration The first few months i was on Zoloft my depression and anxiety were definitely lifted. But in the past month, things have a taken a turn. I'm tired all the time, have gained 10 pounds and can't think straight. This drug has made me feel really stupid and I find myself at aloss for words quite often - simply because I can't think of the right words to use. But my overall mood has been much better which I guess is a good thing. But do i want to be dumb and happy or smart and depressed? Hmmm... I saw my doctor today and am going to switch drugs. I'm a little nervous about the withdrawl from Zoloft after hearing other reports here. I'll be sure to write back with my experience... F 34 6 months
11/12/2007
 5  Depression & Anxiety no side effects after the first week; after the first week, didn't feel like I was "on" anything or "medicated" Zoloft cured my depression and anxiety. My libido has actually improved on Zoloft, perhaps because I am no longer clinically depressed. Zoloft is an SSRI but slightly works on dopamine as well and I think that might give it some advantages over other SSRIs in regard to energy, motivation, etc. 30 minutes of continuous excercise at least five days per week also contributes to SSRI-like mood improvement, which I do. I recommend Dr. Daniel G. Amen's library for all here, especially "Making a Good Brain Great" and "Change Your Brain, Change Your Life." Lots of great stuff in all of his books that you can benefit greatly from. Best wishes M 28 5 years
11/9/2007
 2  depression/anxiety headaches, sexual This drug brought me out of a fog and calmed my irritability. It really was like a happy pill. Too bad the price tag is so high. I took it for 2 months and have been off for a month and still have no libido, no sensation. I hope it's not permanent. I know people who've been off for years and still no return of sexual function. That's too high a price IMO. F 33 10 weeks
11/9/2007
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 4  Depression When I was pregnant the doc told me because it was a class C drug that I had to stop cold turkey..BAD IDEA...I was a wreck for 3 weeks...had the fast head movement/jitter feeling/zapping all over body...Went back on it after my pregnancy and was fine,my last pregnancy my new doc told me to NOT stop taking it cold turkey..thank GOD for him...much better experience...I have 2 healthy,happy children...no effect on them at all. I have been on it for almost 9 years, I have noticed over the past few years it seems to not have an effect anymore so I tried Cymbalta...that didn't agree with me so now I am back to the Zoloft 100mg but it just seems to halp me get by and no sex drive....anyone else? F 28 8 years
11/7/2007
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 4  Anxiety/panic attacks very loose stools, yawning, feel pretty tired I have only been taking this for 2 days, 25mg, so far I have gotten calmer, but it's more like I'm drugged, but that could be the combination of the zoloft and the xanax, cause I'm taking it twice a day. I am not freaking out today, so that is definitely a good thing, I'm going to contiue with this medicine and wait out the side effects and see if this is for me or not. F 31 2 days
11/1/2007
 3  PMDD Blurred Vision I actually really like the Sertraline (for my moods), but then when I ended up with blurred vision which caused headaches I had to stop taking it. Too bad F 28 2 months
10/29/2007
 4  depression and anger stayed awake for the first week or so. None others. Don't ever run out. Cold turkey is dangerous. After 3 days stopping 100 mg a day, I should not have been behind the wheel. A whole weekend went by and I didn't know where I was or what time or day it was. A nurse at the emergency room that checked me vitals, was the only person I remember, beside my two children. She looked at me and said I was being ridiculous, "Zoloft is a day to day medicine and there is no effects from stopping!" This was 5 years ago and I will never forget her stupidity or condescending face. Both my children started laughing at her. On the positive side, I'm much more relaxed in tense situations. If I'm cut off in traffic, I don't flip anymore. I let them in and give a polite wave. the anger is just not there. M 50 10 years
10/25/2007
 4  chronic anxiety with mild depressio lack of sex drive yawning It is a great medication as it has saved my marriage - no one wants to be married to a woman suffering from chronic anxiety and not sleeping, it makes everything pretty stressful - for everyone! F 31 6 years
10/22/2007
 1  OCD, panic disorder restless legs, insomnia, uncontrollable trembling, jitters, complete loss of appetite, weight loss, mood swings, crying spells, extreme depression this is a horrible wretched drug! took it for 2 months and it worsened my anxiety and depression. have never felt as bad in my whole life as i did on this drug. made me feel like my life was hopeless. could not eat or sleep. constant feeling of agitation and needing to move around. uncontrollable shaking.. F 32 2 months
10/17/2007
 3  Depression significant weight gain. Complete Loss of libido. Does work well for anxiety and depression if you can deal with those side effects. I wish this medicine did not have the weight gain/loss of libido because other than that it works great. F 39 2 years
10/16/2007
 4  anxiety disorder Libido down. Causes too much "zip". Took care of obsessive thinking. Only downer is that I now need to take other meds to keep me from being too zippy. It may have triggered a complex motor tic disorder as well. But I don't struggle with thoughts too much. M 31 3 years
10/15/2007
 3  depression/dysthimia Flattening of mood, dry mouth and weight gain. It's the thrid anti depressant I've tried. I was allergic to Effexor and Prozac only worked for a short time. The Zoloft worked and did help my depression for a while, but after a year I don't feel like it's still helping. I tapered off once, but started to feel depressed again and went back on it. Now the dry mouth is really bothering me and I'm considering going off of it again. F 59 13 months
10/13/2007

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