ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)

Average Rating: 3.3 (1667 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

ZOLOFT  (SERTRALINE HYDROCHLORIDE):  Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.   FDA Approval Date: 1991-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLOFTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  depression for first week bad nausea and just a general feeling of being unwell. sleepy alot. these symptoms were gone by one week. the worst thing i have experienced is after about 4 days i started having terrible tightening in my jaws and all of my facial muscles. three days ago i cut my dose down from 50 to 25 mg and i think the tightening/clenching is better so i plan to continue with the 25 mg as i do feel my mood is uplifted from the zoloft already. i do feel a little buzzed at times. i haven't gained any weight and in fact have lost a pound or two because my appetite hasn't been up to par. no bad sexual side effects yet but it has delayed orgasm a little - but this could be me thinking about it too much! i do feel better now that i have been on the drug 2+ weeks and would like to stay with it if i can get past this awful jaw thing. if anyone has experienced this side effect significantly i would love to hear about how you dealt with it so please email me. F 47 15 days
11/5/2008
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 4  anxiety, mild depression rough when I started it, bad anxiety. Then worked well. Had some sexual issues that I remedied by moving the dose, but I started to put on weight extremely quickly and it wasn't stopping. Worked really well on my anxiety, but it caused bad weight gain for me :-( Ten lbs in 3 months. Starting maybe 2-3 months after I started the drug. Finally had to get off due to weight gain and switched to something else. F 27 6 months
11/4/2008
 3  
11/3/2008
 5  depression none whatsoever F 25 4 months
11/2/2008
 5  Manic-depression, OCD Very dry mouth, acne (maybe?) @50mg (I will repost if SE's change and after dose increase. I went on Seroquel and it was great for my mood, but made the OCD much worse, so now I have a different mood stabilizer(lamictal) and added zoloft. I am so happy. I have energy again. F 27 1 weeks
10/30/2008
 4  PMS 2 weeks of miserable exhausted feeling, buzzy like sleep deprivation. Later, increased post nasal drip and thirst. I feel much better now but still increased sinus symptoms and thirst and teeth grinding. Totally worth it overall. I am so glad I stuck it out the first month. My PMS symptoms are so much better, and the side effects seem minor in comparison. F 43 90 days
10/30/2008
 1  severe depression/anxiety Constant nausea, alternating constipation/diarrhea, very anxious, sleepy but can't sleep, clenching jaw, waves of sadness, total loss of appetite, tremors when trying to write, moody and low. lethargic, no desire to do anything I used to love to do, feeling like I want to cry all the time This drug works well for two of my kids, but they are taking it for anxiety only. They seemed to suffer very few side effects. I had taken Prozac for many years, but it wasn't seeeming to help anymore. I never had these kinds of side effects. Have since had trials on Cymbalta, Seroquel and Remeron. I didn't like any of them. I'm only taking 25 mgs of Zoloft in the morning, and it's only been for ten days, but I can't see doing this much longer. I'm already too thin, so weight loss and loss of appetite is not a good thing for me. Everyone says to give it more time, but I don't think this is the drug for me. F 60 10 days
10/27/2008
 3  depression Headaches, mood swings, grinding teeth, feeling low, loss of concentration,anger, suicidal and omicidal thoughts. I started taking it at 100mg and then went on 50mg due to headaches I was also using endep 50mg for insomnia and pain. At the moment I can say that I felt better on 100mg. I still feel depressed and have negative thoughts racing through my mind so I don't think 50mg is really enough for me. M 45 3 years
10/26/2008
 4  Anxiety/PMS @12.5 mgs: First week: stomach ache, very fatigued, brain zaps, sinus. Increased dose to 25 mgs: no more side effects except for mild sinus. Before period (very tender swollen breasts & bad cramps). This is a med you should try to stick with I think. It did help me overall but not with PMS. I was generally more at ease, a little less on edge. I'm not sure about the weight. I quit smoking the same month I started taking it and over that month gained about 4 pounds. I think the weight is due to the smoking cessation, but I've been running about 3 miles every other day for a month and a half and I can't lose a single lb. It might be zoloft related. Otherwise, I would recommend this med. Hardly any side effects when I got used to it. Taper slowly when you get off. F 32 2 months
10/23/2008
 5  BDD, OCD, Compulsive Eating Headaches, Thirsty, 20 lb Weight Loss, Extra Perspiration During Exercise, Lower Sex Drive. Aside from the side effects, which went away after about 2 weeks, this drug has made a huge difference in my life. I will be forever thankful that this medication is on the market. I have a history of mental illnesses in my family and unfortunately I inherited the genes. I no longer feel frustration, anxiety, worry, and the urge to stuff my face. I have less ugly days and don't focus on my "imperfections" as much. Not as many BDD "flare-ups" as I once had. My social anxiety has decreased greatly. I could go on and on... I do not plan on stopping this medication any time soon...as it is a huge part of my survival and my well being. My changed attitude has given me a whole new perspective on life and has improved my marriage tremendously. F 28 6 months
10/20/2008
 3  PMS Loss of libido, weight gain-unable to lose it, weird brain pain on right top side of head. Bad sinus issues, heavy post nasal drip. HORRIBLE diarrhea if I miss one dose. I'm trying to quit this drug but it is hard to taper from 12.5 mgs. I feel more irritable & snap easily. I'm unable to lose weight despite strict diet and exercise. Anxiety isn't much better. No libido. I don't think this is the one for me. F 32 1.2 months
10/16/2008
 4  Anxiety/Depression Clenched jaw...slight headache...little short term memory loss. I have been taking Zoloft for almost 5 years and have had nothing but good experiences except for very mild side effects in the beginning. It does take time for it to kick in but once it does it helps tremendously! F 24 5 years
10/10/2008
 3  Depression mildly sleepy,had 2 short episodes of vertigo the first day,bloating, gas and constipation the first 2 days I am starting out at 25mgs(taken at night)and working up to 50mg. I am also taking this with a combination of 25mg of Lamectil for a mood stabilizer and 1mg of Klonopin for anxiety. I started feeling depressed when I started taking Lamectil which doesn't make sense so I lowered the dose of that. In the mean time because of the depression weather or not its caused by the Lamectil or its a coincidence I am taking an antidepressant. I tried Lexapro and felt like i was going to throw up and felt "coked" out: speedy,my pupils were dialated, colors were a little off, spacey, yawning...it was hard to deal with so I got off and now taking zoloft. I don't really feel depressed all the time only sometimes so this should help. I really don't want to even take this stuff but I'll see if its helps. I will repost something after a few weeks and after moving up to 50 mgs. I have taken so many medications for anxiety in my life and never soley for depression. I have had so many diff F 24 3 days
10/7/2008
 5  Severe PMS When on 50 mg, had jaw clenching--very weird. Lowered to 25 mg, no symptoms. Helps with the PMS, also helped with IBS and overall outlook. F 51 11 years
10/6/2008
 3  anxiety/depression/insomnia constipation, weight gain, loss of interest, sluggish, but after 6 weeks of taking it religiously, I am able to get off of all sleep meds. Zoloft is great for insomnia and anxiety. It takes six weeks to take care of insomnia. I weigh 110 and take 100 mg/day if I want to sleep w/o xanax. If I want to just get rid of the anxiety and "usually" fall asleep with out xanax, I stay with 50 mg. However, I feel really depressed right now. I don't want to do anything! I think we go through cycles, picking between the evils...we get on an SSRI and forget how bad it was before we started on them. What do I do? Take Zoloft, get great sleep, but be lazy and gain weight? Or be skinny, motivated & driven, but anxious & irritable? Oh, and NEVER fall asleep naturally!. Today I have decided to go back to anxious. Ho hum, back to xanax. 10/01/08 F 37 2 years
10/2/2008
 5  Depression/Panic Attacks Insomnia. This is the only anti-depressant I can tolerate. I've tried them all. F 42 10 years
10/1/2008
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 4  panic attacks, general anxiety low sex drive; weight gain; not as passionate about life Side effects decreased when i reduced zoloft from 150 to 100 mg. I truly believe Zoloft has made my life better. I used to wake up in the middle of the night worrying at least 5 nights a week. I had ulcers. I had panic attacks before dentist appointments. When I got angry at someone, I felt like I would explode. All of that disappeared, so to me, it's well worth the side effects. It's nice to sleep and be able to deal with things rationally without worrying i'll have a panic attack or double over from stomach pains! F 35 5 years
10/1/2008
 5  Depression, Bi-Polar, Anxiety Dry mouth, heightened side effects if more than one day's dose was missed (aggression, agitation, restlessness, mood swings) but not severe enough to quit taking it long term. I was on 100 mg for 3 1/2 years when it quit working as well as it had been. It was still helping, just not enough. I was taken off Zoloft and put on Seroquel. Big mistake! I suffered from extreme aggression, agitation, mood swings, and I was unable to feel peace or happiness. I wound up cutting my arm 3 times and needed 31 stitches! I suffered from a mental brake down after 5 weeks of being on the Seroquel and when I had to stay at a mental facility they put me back on Zoloft and increased my dose to 150mg. I was like a new person! I was the 'old', good me again and I have been better ever since. If the Zoloft stops 'working' then increase your dose before trying something else and risk having an adverse reaction like I did. Zoloft can be taken up to 350mg and still be safe, so if it has ever worked for you, please give a higher dose a try. F 25 4 years
9/30/2008
 3  Anxiety Stomach ache, diarrhea, sleepiness, clenching teeth, mild headache, HIGH libido. I had a really hard time making the decision to get on this med after all the scary posts, but I'm determined to find out for myself. Doc said to start at 25 mg but I am going to take it slow. Will document all side effects, good or bad, and post here. F 32 3 days
9/24/2008
 2  Depression/Anxiety At 150 mg: Periods of "zoning out" mentaly, felt like Zombie, uncontrolable eating (carb craving), weight gain, loss of willpower At 100 mg: Depression/Anxiety returned, eating more than usual, weight gain continued, loss of willpower I don't know if it was because Zoloft made me crave carbs, or lose my willpower or what but I started drinking alcohol alot while I was on it. Right about after lunch everyday I would start craving alcohol and I would start drinking right when I got home until I went to bed. That went on for several months until I tryed to stop and had a panic attack. I knew this was not normal for me so I stopped taking Zoloft in hopes that it might be the culprit. I have not had a craving for alcohol since I stopped Zoloft. I have a mostly full bottle of vodka in my cabinet right now and it can just stay there! F 27 10 months
9/24/2008

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