ZOLOFT Reviews (SERTRALINE HYDROCHLORIDE)

Average Rating: 3.3 (1667 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

ZOLOFT  (SERTRALINE HYDROCHLORIDE):  Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.   FDA Approval Date: 1991-12-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZOLOFTCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  depression didn't really work for me-used it because Prozac stopped working. F 43 3 years
1/11/2006
 5  SAD, depression I felt strange only the first few weeks, like I was "drugged," seeing tracers and things, feeling a little nauseated, especially if I took it on an empty stomach, weight loss, and felt numb during intercourse, even though I was still able to have an orgasm, though that felt numb too. I also had racing thoughts and rapid heart rate, and I felt a little jittery. The sexual side affects went away, thankfully, even after I increased the dose to 100mg. Today I don't experience ANY of these side affects, except I do have trouble gaining weight. I was so "against" taking drugs to help with my depression for about 10 years, then I finally decided to give it a try, nothing else was working. I am amazed at how great I feel. I can finally say that I am happy! I feel the best that I have in my whole life. I don't feel any different than my old self except that during the winter months, I feel the way I do on my good days in the summer. The sky was grey for weeks and I was still feeling good!! I can still get emotional or upset, but I am able to express my feelings in an intelligent way. I understand better how I feel and why I am upset, and I can work it out. It's like instead of being overwhelmed by my emotions, the feelings sort of go to my brain, and I can think about how I'm feeling and acting. I can act rather than react. F 23 3 months
1/10/2006
 4  Depression/Anxiety hot flushes, throbbing/racing heart beat, apathy, inability to cry, emotional numbness, dry mouth, poor erections/less sensitivity/decreased libido/diffuclty orgasming,high blood pressure, muscle fatigue/weakness, weight fluctuations, strange/vivid dreams, memory loss, hand tremors, excessive sweating under arms & during activity, What I finnd most alarming is the drug's effect on motivation. Only when I began taking Zoloft did I stop painting, an activity I've pursued from childhood and now professionally. Oddly, I 1st thought this to be a positive sign, a way of beginning anew having conquered depression. And I do believe Zoloft relieved my depression. But after almost 3 years of taking Zoloft, reading the opinions of other users, and a little research, I am of the notion that Zoloft, while relieving me of terrible loneliness and despare, has thwarted the pursuit of my goals, hence the emotionally numb, or apathy charge listd by myself and others. Research at John's Hopkins has found that medicines liked Zoloft actually produce serotonin axon growth, meaning they literally rewire the brain, connecting neurotransmitters. The area of the brain affected, the limbic region, controls smell, emotions, the heart, intestine, stomach, AND motivaion. My question is if such serotonin transports are connected, could the m M 30 3 years
1/10/2006
 1  Premature ejaculation Complete sexual shut-down. Apparently permanent chamical castration. Don't ever take this drug if you like sex because it can ruin your sexual ability forever. M 39 1 days
1/7/2006
 1  Depression Of all of the antidepressants I've tried, this one had the worst side-effects. On the third day, I was climbing the walls (serotonin syndrome, it's called), praying to God to allow the effects to wear off more quickly. The only benefit I got from Zoloft was the relief of having it leave my system. M 58 3 days
1/4/2006
 5  Depression/Generalized Anxiety Weight gain, initial insomnia and nausea that subsided after a few weeks, anorgasmia. I loved this drug, nothing ever made me feel so good, but in the end I was ballooning up. Zoloft just sets your mind at ease, and I'd become this lethargic, happy cow just content to while the day away doing nothing. Wellbutrin was added to counter the weight gain and libido loss, but it didn't help. Only 50 mg/day I gained about 15 pounds in 3 months that I couldn't shake. It took me nearly a year to get it off. It's too bad because it did wonders for my social anxiety and depression. I took this twice -- once from 2000-2001, and again from 2002-2003 and each time I'd gain weight. F 34 1 years
1/2/2006
 5  depression The first week or two was bliss! I loved the stuff. After that came a week or two of nail biting and jitters (like when you drink a quad shot of Starbucks coffee) No negative sexual side effect -- delayed ejaculation like every one else...is that really so bad!!! The only thing is I'm a little obsessive compulsive and that part of my personality has not been damped very much…in the long run, after a year of meds. I like these med lots. I battled for a long time if I should seek meds as a solution to my depression, and after one year and one dose increase to 100mg I feel like a person who is on top of my game. The long dark wet winters don't bother me. I always have the energy and positive attitude to do what I want -- not the negative depressed attitude I used to have. I used to get very nervous about being around other people and interacting with others. Now I actually enjoy being the center of attention and even seek out new friends. I can’t say that I’ve had any negative side effects from taking this medication. Sometimes counseling just isn’t enough to battle having little confidence in your self and a depressed attitude about life. Zoloft just allowed my true inner being (the person I am when I am by myself) to be displayed on the outside…for others to enjoy me as a person; so they can be positively influenced by me. M 32 1 days
12/31/2005
 4  Depression/Anxiety Jaw clenching, teeth grinding (bruxism), slight loss of short term memory. The drug has had a profound effect on my world. I am no longer afraid to live. I see things more clearly, for example, crises no longer freak me out, I can rationalize my way through problems. My desire to be happy in the moment is great, and I no longer worry about what others think of me and what I am doing "wrong." Simply put, Zoloft changed my life. F 49 9 years
12/30/2005
 3  Depression and Panic Attacks Slight headache for the first 2 days (not even bad enough to take asprin) Works fair I guess, I could still feel better F 31 12 years
12/30/2005
 2  anxiety/mild post partum depression dizziness, nausea, extreme loss of appetite, diarrhoea, lethargy, tingling in fingers, sleeplessness, low blood sugar from loss of appetite. Took 1 50mg tab at 10pm and woke at 1am feeling weird. Was bedridden that day. Didn't take another tab but still feeling side effects a day later. I know Zoloft works for a lot of people, but I am breastfeeding and have a 2-year-old to look after, so I can't keep taking it in the hope that the side effects might go away after a week or 2. I need to be able to eat and function. The doctor told me that it seems I have a hypersensitivity. My depression is not serious so it looks like I will have to go down a more natural path to help myself. F 29 1 days
12/27/2005
 5  Anxiety/Depression/OCD #1 side effect for me is sleepiness. I am unable to take my proper dossage for I will be tired and sleeping all the time. Does anyone have an answer to this? The only other side effect is sexual dysfunction however that is counteracted by Wellbutrin that I take. Sometimes dry mouth but that is the least of my problems with side effects. Zoloft is great for me, unfortunately I am unable to take anywhere near the proper amount that I need for it causes me to sleep all the time. This is an ongoing battle that I have had for 5 years now. Does anyone have the answer? I take Wellbutrin to counteract the sexual dysfunction from the Zoloft which is also a good combination in treating depression, however the Wellbutrin was suppose to counteract my sleepiness also but never has. Caffine will only make me anxious and unable to focus so that is not a solution. M 38 5 years
12/21/2005
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 2  Depression Constant yawning, very difficult time falling asleep and staying asleep, over 5 months I have completely lost my sex drive and desire for sex, when attempting sex little or no ejaculation, I have seemed to have lost feelings. I can be excited but not truly happy (my sons team earned a spot in the State Finals in football and I was excited but not really happy), I can be upset but not sad (when my sons team lost the State game, I was upset but without feelings). It seemed that I have lost all feelings about everything. Over the past 4 weeks, I have been coming off of Zoloft and now completely off for 5 days and the side effects are terrible. First were the very vivid dreams that lasted over a week. Now I am having jolting electric "zaps" in my arms and legs, dizziness, motor instability, nausea, abdominal discomfort, flu symptoms, agitation, anxiety, extreme insomnia, aggression, nightmares, tremor, and confusion. M 40 5 months
12/20/2005
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 4  depression mild diziness and buzzing ears F 22 3 months
12/19/2005
 5  anxiety, focus issues Some yawning, delayed ejaculation but subsided, soar throat (not sure if it's due to Zoloft) This stuff really works for me. Be patient, I tried 6 other drugs first. Paxil drove me nuts. Neurontin and trycyclics didn't work at all. I could feel this stuff work the first day, although full effects usually take a few weeks or more. I was actually able to run the NYC Marathon this year. Be careful of what you read on the internet. Most people cured by these meds don't think to post messages. Only the people who are having trouble do, so most of what you read will be negative and this will make you depressed. Find a doctor you trust, ask how he/she can be reached off hours so you know you have a support line, and be patient. It will pay off. FYI I'm at 150mgs. M 5 months
12/11/2005
 1  Anxiety I took this for anxiety,within 4 months i went from weighing 108 to 178 pounds.Three years later i am still battling losing the weight AND have more anxiety trying to lose it!! F 33 4 days
12/7/2005
 5  Depression Jaw clenching at night, yawning (seems to have subsided) I feel like I'm a completely different person on this medication. Before, I was withdrawn, moody, depressed and now I'm ready to live life again. I'm just hoping none of the other side effects hit me (like weight gain). F 26 4 weeks
12/6/2005
 4  postpartum depression At first, a little jittery but this went away fairly quickly. I did develop loose stools, which eventually irritated me enough to wean off this medication. I was no longer deeply, darkly depressed when taking Zoloft. I didn't feel any real joy either, but this didn't bother me too much. I was better than I was before Zoloft! F 30 4 months
12/5/2005
 1  Depression, anxiety, OCD Ringing in my ears, terrible headakes, chest pain I was only in Zoloft for 3 days and had to stop taking it because of crushing chest pain and terrible headakes, will be trying something else, this pill has worked for many people, I guess were all different and I just wasn't one of the people it could help. Any questions or comments or ideas of other drugs I could try, feel free to e-mail me. F 17 3 days
12/2/2005
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 5  depression/anxiety Dry mouth, weight gain, hands sweat. I feel better now that I am on Zoloft. I do not have crying spells anymore and I am a lot happier. I feel like I am back to my old self again. I sleep throughout the night now, but have strange dreams. F 19 4 months
12/1/2005
 5  Depression/Anxiety Decrease in sexually desire and ability to reach a climax. This only lasted about a month. Also Zoloft calmed me down to the point where I wasn't feeling emotions, but taking a complex B vitamin helped fixed that. I believe the B vitamin also helped with conteracting the tiredness. I resisted taking Zoloft, but I am so glad I finally did start taking it. The pains in my chest, due to anxiety, went away. My mood improved back to normal. Life in my head became painless again. I looked forward to waking up again. Life looked colorful again. Before taking Zoloft I was having anxiety attacks. I didn't want to be around people. Every little thing got to me. Sometimes I would get so angry I just wanted to kill someone, or so sad I wanted to kill myself. I don't feel that way anymore. Taking B vitamins along with the Zoloft really helped. The Zoloft calmed me down, the B vitamins made me happy and more energetic. But, just taking B vitamins alone did not work. I am so glad I started taking Zoloft. F 41 1 years
12/1/2005

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