ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  severe nodular acne since teens severe dry eyes, blurry vision, peeling skin, dry rash on wrists and lower arms, slight depression at times. This is my 3rd round. First was in my 20's, second in my 40's. Side effects were not as pronounced and skin cleared up incredibly, lasting for years. This time only cleared up 50% and side effects very difficult to take, especially dry eyes/blurry vision. Now taking every other day. F 54 3 days
5/22/2005
 4  cystic acne Dry skin, rash on forearms, nosebleeds especially in the morning, lower back and joint pain, muscle pain, my eyes hurt badly and developed little bumps on my eyelids that were very painful, some depression, constant exhaustion, sweating eyebrows(what's with that?), problems with vision I hated living with acne all my life but after taking it for 4 months I really don't know if it's worth it. It just seems like at least for now my quality of life isn't that great. Constantly I am experiencing new side effects that are equally painful and/or unpleasant. F 20 4 months
5/16/2005
 5  Moderate to Severe Acne Dry and chapped lips - can lead to a cold sore. (treated well with chapstick). Dry skin and skin peels to reveal new skin esp. on the face (Neutrogena face lotion helps a lot and Nivea for a body lotion). Appetite has increased. Much more emotional and susceptible to crying (drives my husband crazy!!) This drug has helped clear out so much of my skin. I also had acne on my back and it has helped to clear that up as well. The side effects are not enormous when I look at the benefits. I only hope the benefits will last for a long time. F 27 60 days
5/10/2005
 5  moderate acne morning nose bleeds. Extremely dry lips that can sometimes develope into cold sore. Dry tired eyes. Rash that comes and go on the back of my hands and forearms. Sunburn easily. Joint pain(more than I expected). Early in treatment developed nasty cold that had to be treated with antibiotics-FYI don't mix these two drugs. I have been working in a medispa for 5 years and have really tried everything for my acne(glycolic, microderm, blue light, antibiotics, etc) Accutane is the only thing that has positivly changed my skin. F 26 3 months
5/6/2005
 1  Severe acne on back Accutane worked like magic on my back. I was really, really happy to finally be able to wear a T-shirt after hiding my back for a decade. Then a year later, I started to get dry spots. Now I am 31, and have gone through bouts of major depression. I would not recommend this drug, and I want them to fix my brain. I want the happy life that should have been mine. I hate the doctor who prescribed it to me without taking care of the side effects. I have now lost faith in most doctors. F 25 8 months
5/3/2005
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 5  below moderate acne Dry lips, occasional joint pains accutane is freakin great! i've been on it for almost 9 weeks now and it's drastically improving my skin. i have so much more confidence now that i'm on it. it's way better than the other medicine your dermatologists have prescribed you before you have taken it. i totally recommend anyone who suffers with acne to go on accutane. i know side effects vary from person to person, but i haven't experienced anything worse than dry lips or joint paints that arent even that bad. all i have to do is take pain reliever and i'm fine. aaand, my skin used to be really oily that i would always have to wipe it with those oil patch things, but now everytime i feel my skin, its perfectly normal, the way it should be. i really wish i had taken this a few months sooner, when my dermatologist told me about this drug. it's unbelievably amazing! well, i dont know, maybe i'm not experiencing much side effects due to my age. i started it at 15. now im 16 and still continuing taking this...i heard that those older will feel more pain and discomfort on this drug. but besides that... who invented this anyway? its GREAT! good job. F 16 9 weeks
4/30/2005
 2  cystic acne severe heart palpitations, major depression, dry/cracked/bloody lips. mildly clearing up the skin was not worth the continuing heart trauma. F 26 7 days
4/26/2005
 5  Acne, cystic acne dry eyes, dry lips, dry inside of my nose, dry skin on ears, tiredness/laziness, a little bit of joint stiffness This is the best drug ever for acne. It's amazing. I used to have such oil skin/hair, I could shower three times a day and still be oily. Now, after being on accutane for 4 months, I could go for a week without washing my hair and it still wouldn't be oily! It's amazing. My skin is beautiful now, and I get lots of compliments on it. I say if you're thinking of taking it, just try it. And if you do get depression while you are on it, talk to a counselor right away. The clear face is worth it. No bumps or sores on my face! YAY! F 20 5 months
4/20/2005
 5  Nodular and cycstic acne severely dried lips, bloody noses, peeling skin, dry skin I had to go on accutane twice. My skin has never been so beautiful. It looks great. I don't regret being on accutane at all. As long as you've got a tough immune system and can put up with side affects, go for it. You've got a clear face to look forward to and confidence to come along with it. M 26 2 times
4/20/2005
 5  cystic acne No severe side effects except dry lips for my first two episodes of acutane usage. This third time around (20 years later) is different. Dry lips (normal) and some kind of rash on my hands which is now spreading up my arms and back. It's itchy, sore and looks horrible. Doctor says it's a normal reaction but I never experienced it with previous intakes. Honestly don't know if it's a normal reaction to the drug or if it's in anyway a dangerous symptom. Doctor doesn't seem to concerned about it and has given me cortisone cream. Took accutane in my early 20's (still experimental then) and again in my later 20's. Went 20 years with pretty much no cystic acne problems and now it's came back again in my 40's. This is the 3rd time I've been on the drug but it is the only drug that eliminated the cystic acne for me. All other prescriptions were worthless. F 43 3 months
4/15/2005
 3  severe acne severely chapped lips and dry skin, bloody nose, muscle soreness, joint and lower back pain, dry eyes, sunburn easily, high cholesterol good results on face, but not on my back, but the side effects are horrible, higher than usual doses M 16 7 days
4/7/2005
 5  acute acne on face and neck dry lips, dry forearms which developed into a rash when I sweat I didn't suffer any mood swings or depression from the drug. I swear by it. I had wrestled with the decision to take accutane for years and I wish I'd taken it sooner. F 28 7 months
4/5/2005
 4  Acne Dry lips, a little joint stiffness. I took lose dosage accutane, only 120mg a week, basically a pill every other day. It works, no question about it. Not sure if it is worth the expense or the side effects. I would never go on a full blown course of it. M 29 12 months
3/31/2005
 5  nodular scarring acne for 15 years dry lips, dry cracked hands/knuckles, dry skin generally It's easy to give in to hyperbole and call this a miracle drug. But that's how I felt. For me the depression caused by acne was occasionally horrible. This drug worked quickly and even after going off, acne was rare, not nodular, and very tolerable. I wish I had taken it earlier. Now many years later I get an occasional acne lesion, and I sometimes would like to take it again, but the dermatologist i saw discouraged me. If you have bad acne, that scars your skin, or scars your psyche and self-esteem, seriously consider this drug. Its not perfect, but get informed and if your skin is bad enough and you understand the risks, it can be a lifesaver. The person who makes a better accutane will be a billionaire. M 30 6 months
3/29/2005
 5  bad acne headaches, extremely dry skin F 19 6 months
3/22/2005
 1  Severe Acne Sudden and severe depression at the end of the 5-month period; this got significantly worse in the weeks after going off the drug. Any web search on its side effects reveals so much to worry about (class action law suits, over 100 suicide cases, and more) that I don't think anyone should be taking this drug without a LOT of research. M 17 5 months
2/27/2005
 5  Cystic acne The main side effect I had was flaky skin. Near the end of the third month, I got odd bumps on my knuckles and small black lines (look like splinters) under my nails. My derm referred me to a cardiologist, who found nothing wrong. I've been off of accutane for two years, but I still get knuckle bumps and nail lines intermittently, along with lips that peel constantly. I love my skin now. I actually get complements on it! Though my skin is still oily, it's not nearly as oily as it was - and it's remarkably clear and smooth. Well worth the mild side effects. F 27 3 months
2/22/2005
 5  Cystic Acne Lower Back - joint pain, dry lips, lethargy, sweaty eyebrows (just noted that someone else had this!) I have been pleasantly surprised - My face is finally clear! I did get breakouts on my back - the only other time was when I was pregnant 10 years ago! Good to know that I dont have to look like a teenager as I enter my 40's! F 39 4 months
2/22/2005
 3  cystic acne VERY BAD hair lose. My lips have been cracked and my skin and scalp are very dry. If it weren't for the hair lose it would be great. I could tell a difference in my skin a week after I started it. F 27 3 weeks
2/21/2005
 1  acne Tried to commit suicide I have never had any sort of depression history in my family or in my life. I figured since this drug was doing what it was supposed to be doing...making me feel better about myself, then why would I be depressed. I honestly thought it was hype about the depression, and I didnt believe it. 5 months after being on the drug, I began having severe mood swings. I would lay in bed all day and just cry. Finally one night out of nowhere, I tried to kill myself. Now my entire family thinks I am insane, and I dropped out of college, because everyone knows. I had to stop taking accutane because it made me nuts. AND to top it all off, I've got pimples again. So I dont even know which is better. F 19 7 months
2/14/2005

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