ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Scarring acne, inherited Extremely dry lips and eyes, dry skin and nasal passages I spent years dealing with acne, trying every medicine out there. They might work for a few months, but then it was on to something new. Accutane cleared up my acne (with the exception of the occasional hormonal outbreak). All I have left are some slowly fading scars! F 27 7 months
10/17/2005
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 2  acne very dry, chapped and peeling lips, increase in acne, depression related to the increase in acne, dry eyes, hair i was on accutane for six months. i don't believe that its improved my situation. i am still getting cystic acne although i went off the medication about a week and a half ago. it is so disturbing, especially since the dermatologist claimed that this would "cure" my acne forever. they really should not make such claims, because they are not true. there's unfortunately a percentage of people for whom accutane does not work, and i guess i happen to be one of those lucky few. lol. the first 3-4 months were absolute hell and my acne increased tenfold during that time. i seriously did not want to leave the house at all. i have less acne now, but its still a problem for me. i think i will try going back on minocycline at this point. F 36 180 days
10/1/2005
 5  scarring cystic acne dry lips,dry eyes,dry skin, trace amount of blood in nose This is my third time using accutane.I have PCOS and it is a hormonal syndrome/disease that causes acne.I have been on antibiotics in the past to no avail.I first took accutane when I was 19 and again about 2 years later.I am so thankful for this medication.I have had joint pain for about 6 years and I don't know if it is from the accutane or not.I just know that if it wasn't for accutane my life would have been very different.It is very emotionally draining to have acne, especially when you are left with scars.They are not only physical.I can't wait for this to start working.I am excited to start seeing the results!! F 30 1 weeks
9/19/2005
 5  acne Extreme chapped lips for the entire 5 months. A bit more emotional at times. It was the only thing that worked for me. My acne was not extreme and so doctors often tried to cure it with antibiotics. Went on them 3 times, they never worked. Also was on Differin, RetinaA, Proactive, etc. Finally insisted on trying Accutane. The side effects can be serious, you have to sign this entire booklet before you go on it. But the only real side effect I noticed was chapped lips. Looking back, I may have been a bit more emotional/sad at times, but it didn't really affect me. My skin is clear for the most part. Still have some scars and a few breakouts, but I can't complain...it's way better than it was. F 19 5 months
9/19/2005
 3  mild to moderate acne on face Severe knee pain - found it hard to walk up and down stairs or sit for periods of > a few minutes, dry, cracked lips and corners of mouth, ugly red itchy rashes all over my body (worse on hands, wrists and arms), severe tiredness, reduced immunity, general joint and muscle aches, sweaty eyebrows, sensitive, fragile skin, dry skin all over, red, inflamed and peeling skin on areas of acne, dry sore eyes, peeling skin in ear crevices and around nasal passages, increased cholesterol levels. I am extremely unhappy with the side effects and am hoping that they will pay off in the end. My acne is still there mainly around my chin and jawline but has gone on my forehead. The lesions arent as painful but seem to take a very long time to heal. I am still experiencing breakouts that are extremely depressing to the point where I dont want to leave the house. My side effects have really worsened since increasing the dose. F 26 2 months
9/1/2005
 1  cystic acne Cracking and bleeding from every mucus membrane I had. Drying of my joints (knees, shoulders, fingers). Till this day I cannot sleep on my side unless I sleep on my scapula due to pain in my shoulder. Hair loss, hair loss, hair loss! Irritable bowel syndrome (maybe)... I think its worse as I am chronically constipated. I seldomly have pain as I won't have a bowel movement for over 2 weeks unless I take drastic measures! I can't smell due to chronic edema in my nose. My face has no more acne, scars stopped forming after I completed my course but.....NOT WORTH IT with the MAJOR SIDE EFFECTS. To use the rest room once a day... priceless. I weighed 100lbs. Took 40 mg for extended period. F 43 1 years
9/1/2005
 3  cystic acne CHAPPED LIPS, stomach ache, tailbone always hurts, dry skin. I haven't really noticed any change yet. For the amount I paid for the medication, it better start working soon!!!! I am disappointed so far, but hopefully it will change. I would pay more if I knew it was going to work. So if it does make a difference it is well worth the cost and the side effects. F 26 4 weeks
8/26/2005
 2  Adult Acne Chapped lips, very dry skin. I've been taking it for almost 5 months now and it still didn't clear up my skin! I don't get it. I'm still having a lot of those very red breakouts... In addition to all the side effects (flaky lips are the worse part in my opinion), I'm having doubts about the eficiency of this medication. Can I be resistant to it? F 27 5 months
8/25/2005
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 4  acne dry throat made me cough frequently, dry nose, dry and cracked lips F 45 4 months
8/23/2005
 3  Moderate Acne Chapped lips, Bleeding gums Im optimistic about treatment. Yet this is pretty serious stuff. Within a week my lips were getting chapped pretty bad. Also, last night I brushed my teeth to a crimson surprise. I have pretty decent dental habits and history. I experience mild gingivitus time to time and it usually solves itself with good brushing and some listerine. This time around, I couldn't believe how much blood there was. Fortunately, this morning wasnt so bad. The sore seems to be localized to one tooth. I really hope this is worth it.... 25 days
8/22/2005
 5  cystic acne dry lips (Normal), joint pain (especially tailbone and hips), No oil in hair, painful bowel movements, easy to sunburn My acne is now 98% better and my side effects are subsiding well (have been off medication for 1 month). F 24 5 months
8/13/2005
 3  Severe Acne dry lips, headaches, stomach aches, vomitting, itchiness, and dry skin mostly on my face. I never had a problem with acne really my entire life until a year ago. It started on my back and has now moved to my chest, neck, and face. I never knew how having acne could impact my life. I honestly don't leave the house sometimes. I don't know how many times I said F 26 10 days
8/6/2005
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 1  acne, cystic acne dry nose, dry eyes, joint pain, extreme tiredness and fatigue, hair loss, unable to concentrate, major tiredness, feelings of sadness, crohn's disease While I was on it, I loved it. My skin, still, looks awesome and is perfectly clear. But, because of this medication, I cannot study and concentrate like I used to in college. I got Crohn's Disease from it (a terrible intestinal disease that has NO CURE!), and I am still unable to concentrate and am very tired. The clear face was not worth the embarassing, un-curable bowel disease. This drug is really bad. I would bear with the acne and save your body and you mind from the harshness of this truly un-safe drug. F 20 5 months
7/14/2005
 2  Moderate Acne on Face only **Immediate**: Dry lips, thinning of hair at hairline, grayish palor to skin, slight stomach pains, depression, dry skin **Long-term**: Acne is back and worse now on back, chest and neck. Worst side-effect of all is the dry skin around my anus which now bleeds everytime I have a bowel movement. While the accutane began to clear up my acne, I stopped after only two months because of the side effects F 28 60 days
7/10/2005
 1  30 years of acne nosebleeds, dry cracked lips, personality change and loss of smell and alteration of taste. Smell and taste took 8 years to return. Still not 100 percent. Acne was gone while on product. Came back when off. Many side effects not listed or known.This is a very serious drug. I do not know if it messed up my heart.Think twice before taking this drug. F 49 90 days
6/25/2005
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 5  Moderate cystic acne dry lips,nose,eyes,skin. pretty bad lower back and hip aches towards the end of treatment. Anus tears and mild BM problems eggasgerated from previous problems My skin looks great. I had really oily skin and hair and that went away. I mainly had cysts and they are of course gone and were by the end of my 2nd month. stopped the treatment about 2 weeks early because the lower back pain was concerning me. It was worth it so far. took it for about 4 and 1/2 months 40mgs then 60mgs F 23 20 weeks
6/21/2005
 4  Moderate to severe acne Dry skin, dry lips, dandruff, increased sensitivity to oncoming headlights at night when driving, decreased sex drive I've been on accutane for one month so far and it seems to be working fairly well. I started seeing results after about 5 days. A lot of people have warned me about the depressive side effects of the drug, but I feel I was more depressed with my skin the way it was before. I don't think anyone looking to go on Accutane should be influenced by other people's opinions; there are very serious side effects which each person themselves need to consider, however for me I believe the medication is working. F 22 30 days
6/9/2005
 4  acne face and back VERY chapped lips, dry and sensative skin all over, my hair was very shiny, but my skin and my face hurt pretty much the whole time i was on it, the skin where i had acne was very dry and flaky its very annoyning, and the side effects i experienced were hard to handle, and hard to hide, it was visually obvious i was on some medication, but now i have no zits and i have been off it for 3 months, it was worth it F 21 9 months
6/1/2005
 3  Acne Chapped lips, acne got much worse. It's been only 40 days that I'm on Accutane. At first, my skin looked great! But after a week, I started getting this huge zits all over my face (not on the forehead though). Now, I'm looking pretty bad, and I even started taking some antibiotics to help treating this breakouts. I'm hoping this medication will finally cure my acne. Although I do get sad with the fact that my skin got much worse, I'm still on my normal mood. Not depressed at all. F 27 40 days
5/31/2005
 5  Lifelong acne dry lips, hair loss, dry skin, reddish skin, skin got worse for about a week before it got better. Now it is almost completely clear for the first time in my life and I am not mopping oil off my face constantly. I've had acne for 47 years -- complete with cysts, breakouts on my neck, chest, back, even inside my ears! It would get worse, then get better, get worse, get better. My make-up was oil soaked within 30 minutes of putting it on. My hair was oily and stringy and had to be washed every day. This is the first time in my life that my skin has been clear and at age 58, its about time!!! I thought long and hard (6 months) when my dermatologist recommended Accutane, so I didn't make a snap decision. The side effect that worries me is the hair loss. I hope it tapers off some or stops. Barring that I hope it grows back when I finish the medication. I have a history of major depression, so I am watching closely for any problems there. So far, my mood is stable. Recommending a medication to someone else is iffy --- each person has to decide the risk-benefit ratio for themselves. F 58 3 weeks
5/29/2005

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