ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Severe Acne It dries your entire body SEVERELY. You might just be able to see the outer skin dryness, but what what you don't see is the internal dryness that this drug causes. I had joint pain to go with the dryness. Acne disappeared completely, BUT i would rather be dead than like this. I am more depressed now than i was when i had severe acne. I was doing treatment when i was 17. Now 5 years later the side affects have killed me as a person. I use to be the most athletic, muscular, outgoing, funny and charismatic guy in my school. The only problem i had was acne and now since the treatment i haven't had a single zit on my face or body. BUT, I have lost 40 pounds (i now weigh 130 and look like a twig). I had a successful knee surgery two months ago because my bones are brittle. I use to have a 20-20 vision, now i am blind without glasses. I had to shave my head because of extreme hair loss. It hurts when i pee and poop. I use to be a great student, but now i have dropped out of college due to depression and lack concentration. In the past two years i haven't slept well a single night and i've been having constant thoughts of suicide. I have a hunch back now. None of my friends talk to me anymore because of the jerk i have become. I think my family has given up on me too because i'm getting worst day by day. I'm preying to god to take my life, I don't wanna live like this, I'm a burden on everyone's shoulders. People that have rated this drug a 5 have only been off the drug for a month or are still taking it. PLEASE DO NOT WASTE YOUR LIFE FOR THIS. The side affects trigger about a year after treatment. There's no way back for me but you can still save yourselves from this monster of a M 22 6 months
30 MG 2X day
10/5/2011
 2  severe acne Accutane only worked while I was on it. The acne returned after about two months of being off of it. The long term problem I have from accutane use (14 months later) is chronic dry lips with a clown line around the outside of the lips. I have tried everything under the sun and well as allergy testing. It was not worth it to me to have permanent clown lips and have the acne return. M 18 20 weeks
40 1X day
10/2/2011
Email
 1  Acne Please do not take this drug if you enjoy who you are. I miss who I used to be. After taking the first accutane pill I have had chronic constipation. While taking accutane I fell asleep for three days and woke up extremely aggressive and irritable for the next two weeks. My friends were afraid of me. Since stopping accutane, my constipation has not gone away. I have to take laxatives twice daily, and I have intense nervousness and anxiety from accutane. I was a successful 21 year old musician, and I am now a pathetic 22 year old who fears going out doors. I'm not joking. I have seen several doctors and been to the ER several times for feinting, intense migraines, and lives issues all developing after taking accutane. I have met with the inventor of accutane, and no help there. I finally consulted an eastern/wholistic doctor who has prescribed me 5,000mg of fatty acids / 200mg l-trytophan daily. I recommend this to any one who has used accutane and suffered from side effect M 22 14 days
50mg 2X day
9/28/2011
Email
 3  Acne Dry Chapped Lips, Extreme Stiff neck and pain in neck, dry nose, but no bleeding So far I am liking the results. If I do "break out" It seems to dry up really fast. The stiff neck thing is becoming more and more of a problem. It has been going on for a week non stop. In the morning I can hardly lift my head off my pillow and have to turn my whole body since my neck is stiff. Im trying to grin and bare it. Just hope it goes away. F 28 30 days
40mg 1X day
9/27/2011
Email
 4  acne dry skin around lips helped a lot M 29 4 months
20 2X day
9/26/2011
Email
 5  Severed Acne Dry/reddish skin, dry lips (peeled constantly) After several visits to my dermatologist, I finally decided I'd had enough of my acne nightmare (I was still in high school, need I say more). I switched doctors, and the new one immediately put me on accutane. Approximately 2ish months later, my acne was gone, completely. I've never had a problem with acne since, and I'm now 33. This was like a miracle drug. M 33
2X day
8/16/2011
Email
 4  stubborn but mild acne mostly Mild dry skin and lips joint pains Tiredness Chest pains Thin skin (but I had thin skin before) Eyes not dry or irritated No body dryness. No rash or any patchyness No depression or moodyness out of normal Loss of appetite All very mild and tolerable I started out on 10mg a day for 10 days, then moved onto 10mg twice a day (morning and night- 12 hour intervals) for about 2 weeks then now on 20mg a day. Been on isotretinoin for about 9 weeks now (little over 2 months). For the first 2 or so weeks, I had the initial breakout that was pretty bad for me since I have never had that many cysts, pimples, or whatever. I had about 30-40 at one time and it was red, a lot of hard ones and some with whiteheads that were ready to ooze out- it was so frustruating and hard for me. To give you some idea on what my skin was like before this and why I decided to go on it: I struggled with my skin all my life. I am 35 but look early 20s and usually, most people think I have great skin because I am a full time model and I know how to cover them. I've always had stubborn acne that would take forever to go away or come up and when it did, it would become a whitehead and I would either pop them myself to flatten them or go to a facialist and have them do it (which heals better and doesn't look as scabby and big) But towards the end and right before starting isotretinoin, my skin was hard to control. Esp. hiding it from my bookers and casting agents, etc. was becoming impossible. I knew if I didnt have this in control, my career would be down the drain overnight. I took a 'leave' from my work and took the plunge to take this controversial medication. I did my research for months before this and knew exactly what I was getting into. M F 35 6 months
20mg 1X day
7/8/2011
 5  facial acne at age 28 nasal dryness, chapped lips For me, Accutane is a godsend. My skin started breaking out terribly when I was 28, and I didn't know what to do, it was so unsightly. During an eight month course of Accutane, my skin was absolutely perfect, and since then, has been beautiful for the last two decades (I am now 49). I am so thankful for Accutane. F 49 8 months
20 mg 2X day
6/24/2011
Email
 5  Severe Nodular Acne NEXT TO NONE. Dry lips that peel about once a week. Dry skin. Even my doc was impressed with the lack of side effects and my dosage 80mg/day (2nd month+, 1st month was 40mg/day) That's it! No fatigue, aching, psycho suicidal thoughts etc etc. Use Aquafor at night and it will save them! Just blistex chap stick a few times a day. Just use a good moisturizer every morning and i was fine! This has been an absolute god send! My skin is amazing now and i get comments all the time about something is just "different" about how i look (i used to cover it all up with makeup so now there's so much less of it.) F 26 7 months
80mg 1X day
6/24/2011
Email
 5  For acne on my face The side effects were horrible.. my lips were dry 24/7 but after about 4 months of taking it my skin was legit flawless! i couldnt be happier :D totally worth it F 16 6 months
2X day
6/21/2011
Email
 5  severe cystic acne very, very dry lips I am not a pill-popper (Tylenol expires in our medicine cabinet!) but my Acne experience had made me desperate for a cure; this drug completely cured my horrific adult onset acne in a matter of months when I was 30 years old. . . I am now 36 and have beautiful skin (no scars). My doctor monitored me closely throughout treatment and now our 16 year old son is taking Accutane ~ praying for the same amazing results; so far so good! F 30 4 months
50 1X day
6/20/2011
 5  Cystic Acne Dry Lips, bad initial breakout Don't second guess Accutane, just do it. I struggled with acne since grade 5 and decided to go ahead with Accutane while in my 2nd Year of university. I finished my treatment two months ago but haven't had a single pimple during the past four. Although the initial breakout is definitely a pain in the arse to get through physically and emotionally, it's all worth it in the end. My only complaint is my skin is back to being as oily as it was before.. I miss having dry skin and non-greasy hair! If you have any questions feel free to email me. F 21 4 months
60 mg 1X day
6/20/2011
Email
 1   Neighbor's kid is taking in and he was a normal happy kid with a few zits. Now he's sullen and has violent outbursts. I hope he kills the doctor who gave him this poison. This is just one of many of the poisons big pharma is pushing. There is no need for a drug like this. The FDA should ban it but they are as bad as the drug companies who own them. M 17 4 months
40 1X day
6/1/2011
 2  Server acne At the time of taking it, I was depressed, moody, had hair loss, dry lips. But it did clear my face up eventually. I havent had a pimple in nearly 3 years. I have all my blackheads back though. A year after accutane I was dignosed with a 23cm cyst on my left ovary which had to be removed, aswell as the tube. Now I'm getting the same thing going on, on my remaining ovary. Have a cyst on my kidney aswell as kidney infections and still have hair loss and dry lips. I'm still depressed every day of my life and have major mood swings and crying fits. I never had any of this BEFORE accutane! F 22 11 months
40mg 1X day
5/19/2011
Email
 2  white huge pimples filled with pus i'm off the accutane for four months already, and the majority of my eyelashes and eyebrows are gone. Every day I experience a terrible loss of hairs. my eyes are incredibly dry and it kills to blink, to see in the light, and to read. it's a great drug to clear your acne but consider the side affects. I'm extremely pissed that I took this drug. F 20 4 months
40 mg 1X day
5/10/2011
Email
 5  Acne Dry flaking skin on hands and inside nostrils. Whilst some people have had terrible experiences using this, I found it to be the thing that saved my life, as I was very insecure about the proliferation of acne I had. Five years on, and not a single outbreak has occured. M 16 5 months
30 1X day
5/5/2011
 1  Acne Joint and muscle pain throughout the body. chest pains. Abdominal pain and constipation. Lethargy. ( ISOTRETINOIN ) knowing what i know now i would NEVER have let my 16 yr old son take this medication M 17 5 weeks
30 1X day
5/3/2011
Email
 1  Severe Acne During treatment: Dry skin, chapped lips, thinning hair, major itching when my body would heat up through excersise or other activities where my heart rate went up. Minor joint pain and stomach aches. This is a caution for those who consider this drug! I am 41 years old, and took accutane when I was 18 due to cystic acne on my face, chest and back. I figured it was puberty! I am male and at 18 was a serious athelete (Top 1% at just about any sport), don't drink or smoke, 6' tall 185 lbs and 4%-6% body fat. I spent a couple hours a day lifting weights, basketball, MMA, swimming, racket ball, competitive team sports, soccer, football, skiing. I have been into fitness since I was a kid and was truly in the best shape of my life. While on accutane I began to have joint pain in my knees, shoulders and back. I increased my water intake and continued with my active life style. Within 6 months, my knees were so bad I had to stop playing basketball. I went from jamming the ball to sitting on the bench. At 20 years old, both shoulders hurt and my mid and low back began to give me trouble. At 21 my back was so bad I could not work and went back to school. Accutane drys your body out so much and your joints end up taking significant abuse. Now after 3 knee surguries and cortizone shots in my back to function, I am living with joint pain beyond my years. In addition to this, I had an appendectomy at 21, and then went through a period of what I thought were ulcers, with fatigue, irritability and migrane headaches. I lost the ability to consume any alcohol. A good thing, YES, but my body would react crazy if a single beverage was consumed. 3 day hangovers from a 6 oz beverage! T M 41 6 months
n/a 2X day
4/23/2011
Email
 4  Severe acne Fatigue, cracked lips, slightly dry skin, severe mood swings, frequent stomach pain, migranes I took accutane for about four or five months then moved, so I had to come off of it for a while. But about two months ago I started again, but my doctor had me at 60 mg a day. I had really bad mood swings and my depression is getting a bit worse. (My mom thinks it's because of the residual accutane from before we moved) I'm always tired and my energy level is frequently low. F 15 2 months
30 mg 2X day
4/3/2011
Email
 1  acne dry everything!! it worked alright but now a few yrs later (16-20yrs old) i have constant intestinal pain and fluctuating constipation and diarhea. i was and am a very healthy girl...i jus have VERY painful insides!! i understand the desire for beauty but....try something else!!!! not worth the pain im in now!!!! wish i could save everyone from this!! :'( F 20 6 months
30 ? 2X day
4/2/2011

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