ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  acne Tried to commit suicide I have never had any sort of depression history in my family or in my life. I figured since this drug was doing what it was supposed to be doing...making me feel better about myself, then why would I be depressed. I honestly thought it was hype about the depression, and I didnt believe it. 5 months after being on the drug, I began having severe mood swings. I would lay in bed all day and just cry. Finally one night out of nowhere, I tried to kill myself. Now my entire family thinks I am insane, and I dropped out of college, because everyone knows. I had to stop taking accutane because it made me nuts. AND to top it all off, I've got pimples again. So I dont even know which is better. F 19 7 months
2/14/2005
 1  acne Tried to commit suicide I have never had any sort of depression history in my family or in my life. I figured since this drug was doing what it was supposed to be doing...making me feel better about myself, then why would I be depressed. I honestly thought it was hype about the depression, and I didnt believe it. 5 months after being on the drug, I began having severe mood swings. I would lay in bed all day and just cry. Finally one night out of nowhere, I tried to kill myself. Now my entire family thinks I am insane, and I dropped out of college, because everyone knows. I had to stop taking accutane because it made me nuts. AND to top it all off, I've got pimples again. So I dont even know which is better. F 19 7 months
2/14/2005
 5  acne, nodular acne on neck and back Dry lips, My face is getting really dry and therefore causing a little flaking and is also a little red. So far so good. When I started taking it I had nodular acne all over my back and neck and spotty acne around my lips. I have already noticed that most all the nodules on my neck and back are clearing up and my face is doing better too. The drying effect on my lips is a little aggrivating, but its already been worth it. Two weeks taking it, and no new zits. If this keeps up I will be very happy. Some of the people on here want to blame accutane for there problems, but I think some of there problems would have existed regardless of accutane. Sometimes on these sites you see a lot more complaining than you do praising and thats just human nature, If everything is working good you dont usually post anything. I am making this post for all those out there considering it. I waited a long time to do this and wish I would have done it earlier. I know I have not been taking it long, but let me tell you, so far it has been great aside from the dry lips, which to me is worth it because I am getting rid of this ridiculous freakin acne. M 32 2 weeks
2/9/2005
 5  bad ance; nodular & cystic Dryness of eyes, inside of nose. Severly chapped lips. I have only been on it for 1 month so far. i will continue for the next four months. I have seen an incredible difference so far and nothing has helped me to this extent in the past. The chapped lip are annoying, but totally worth it. I am 20 and past the teenage hormonal stage, so I don't know if it would have cleared up on its own. I have had few breakouts since I started the treatment and I noticed an incredible difference right away. My skin actually feels soft. I feel more confident about my skin too. I understand that it affects people differently, but one should not rule out trying it just because they have heard bad things about it. You and your doctor know what is best for your body and if it helps, I am working with one of the top derms in the country who would not recommend the drug if you were not a good candidate for it. F 20 4 weeks
1/29/2005
 2  Acne-last resort medication Extremely dry skin to the point of cracking and bleeding. I had a scab on my nose for most of my treatment. I was severly depressed and have had cycles of depression (with suicidal thoughts) for the 11 years since taking it. I also developed Irritable Bowel Syndrome (IBS). It cleared up my severe acne, but I still break out, even on Ortho-tricyclen, which is a birth control that's supposed to help acne. I know how it feels to want clear skin so bad that you don't care about the side effects, but my life has been severly impacted by the depression and IBS that I developed (most likely as a result of Accutane). F 27 6 months
1/26/2005
 5  
1/12/2005
 1  cystic acne I did two rounds of that crap in 1997.My skin cleared up.However I started having heart palpitations which have not stopped now for several years. Will they ever stop? Would I trade clear skin for these disturbing side affects? No, I am scared about what the future holds. This is a scary drug. I would never do it again F 48
1/8/2005
 1  cystic acne I did two rounds of that crap in 1997.My skin cleared up.However I started having heart palpitations which have not stopped now for several years. Will they ever stop? Would I trade clear skin for these disturbing side affects? No, I am scared about what the future holds. This is a scary drug. I would never do it again F 48
1/8/2005
 4  ACNE DRY LIPS, HAIR HAS NO OIL IN IT, WHICH WAS NICE. EYES GOT A BIT DRY, BROKE OUT THE FIRST 6 WEEKS I WAS TAKING IT. F 22 4 months
12/29/2004
 3  moderate to severe acne Just about everything the book warned of - tiredness, sore joints and dry skin, painful eyes, painful bowel movements, stomach cramps, general sense of exhaustion and lethargy, and heartburn - I could feel food crawling down my dry throat and oesophagus. However, the whole time I was on it, I did not have one pimple! The treatment hasn't cured my acne, but it's made it a lot better. I've gone from ugly, huge, cystic welts to a smattering of pimples. I had to give up martial arts and weight trainign after a while, and I think I have done quite severe damage to my joints. Was it worth it? At the time, yes. I was paranoid as hell about my face, and it was affecting my career (who wants a spotty employee in a high end professional job?). However, I fear that in the long term I may well change my mind. F 28 12 months
12/23/2004
 3  progressive acne complete absence of oils in my skin and hair. No earwax for about a year. Sweating in my eyebrows. Extremely painful bowel movements due to lack of normal body lubricants. My acne was completely gone for about a year then started to progress, although not as badly as when I went on to Accutane. I am now using Proactiv to control my acne with very good results, and no side effects. I would not do it again. F 33 6 months
11/19/2004
 5  acne dry and cracked skin, eyes, nose, lips, ear skin; easily sunburned i took the drug twice and both times it cleared up my skin. it's been much clearer now for about 5 years. in my case, the results were definitely worth the discomfort. (acne itself was at least as uncomfortable!) F 27 6 months
11/18/2004
 5  Acne tired all the time, dry skin It was totaly worth it I have been off it for 3 years now and nothing has come back M 16 4 months
11/11/2004
 5  Acne Dry skin and lips, almost no oil in my hair (nice!), some joint and bone pain, bad lower back pain towards the end of treatment, redish skin tone, acne got a whole lot worse the first two months of treatment. A lot of people talk about depression, how accutane can cause suicidal thoughts, and that the drug should be banned. I do not deny accutane could have caused such things in some people, but this does not mean people should avoid the drug. During my whole 6 months of treatment my best friend relapsed into cancer, was diagnosed as terminal, and passed away. If accutane was going to cause any kind of mental problems with me it surely would have done so with all that I was going through, but I experienced nothing besides normal grief. And believe me, my doc was watching me VERY closely! So apparently some people may have problems with accutane, while others like myself don’t. The decision should be made on a person by person basis, and I would do it all over again. For some people, it is a miracle drug! My skin is great now though I still have a few zits every now and then. F 19 6 months
11/5/2004
 5  acne dry lips, dry skin, dry eyes (could not wear contacts), weird ear wax, extreme exhaustion, severe joint pain I used Accutane in 1998-99 for approximately 6 or 7 months. I experienced pretty bad side effects, but feel it was worth it. I would take it again in a heart beat if it was necessary- which it is not. Went 2 full years w/o breakouts. Now I get 1 or 2 pimples during my monthly cycle that go away fairly easily. F 40 7 months
10/19/2004
 5  Acne Dry lips It's been a miracle cure for me - I am going on month 5 and I would do it all over again if need be. My skin looks fabulous and I barely had any side affects! F 29 4 months
10/5/2004
 3  cistic acne dry lips, skin, and severe redness and burning of my eyes. This drug is not worth the side effects. This drug is only now working after 5 months of being on it. In addition, I am taking 2 other drugs to help. I hae taken accutane when i was younger and saw no difference, but did not get the side effects. This is a rotten drug! F 20 5 months
9/13/2004
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 5  severe acne dry lips, nose, skin; sensitivity to the sun, joint pain; painful intercourse b/c of dryness recommend taking it only for a short period of time-side effects get worse the longer you are on it. M 29 5 days
7/21/2004
 5  super bad acne suicidal thoughts, very dry skin and lips, sore eyes, became less involved in activities, got angry at times, headaches in my case its worth the side effects. dont take this drug lightly M 15 3 days
4/19/2004
 2  acne- nodular Sore anus when having BM and stomach aches that seemed to be related to the tender/tearing tissue in my body. I think what was happening on the outside of my body (severe dryness) was happening on the inside. Also, my cervical mucus was almost non-existent and made sex unenjoyable. About a month after stopping the drug, all these symptoms had vanished. Accutane did clear up my acne some. I no longer have the big nodular zits that I once did, but now I seem to get acne in places I haven't before. I stopped taking the pills after 4 months because the side effects were unbearable. F 29 4 months
3/23/2004

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