ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  
1/26/2007
 1  mild acne long term side effects include extremly painful back,insomnia, depression,anxiety,lost of interest in things that I used to enjoy,hip and muscle pain,tiredness,blurry vision,muscle soreness, joint and lower back pain, dry eyes and lips. I took this posison 3 years ago..I am still suffering from all these horrible side effects. Lower back and insomnia are horrible enough to make me think of suicide. M 28 3 months
1/22/2007
 4  cystic acne I have recently ended my near 1 year run with accutane. It really geared me towards a healthier lifestyle, which was great. There have been some negative side effects, however. The dryness is most notable. Every morning (more so now than when I was on the med), dry throat, nose, EYES, skin. Also, there have been some new pimples showing up, which I'm getting totally scared about. My digestion is kind of funny as well, sometimes I'll feel extremely sick if I don't get water. All in all, I fully recommend accutane as a LAST RESORT because my skin did clear up remarkably (after months of dedication to the drug) Try other meds first, stick with them, be consistent, and DONT GIVE UP. Accutane is no miracle...it takes a confident person who's willing to make a lifestyle change. F 24 11 days
1/21/2007
 4  cystic acne I have recently ended my near 1 year run with accutane. It really geared me towards a healthier lifestyle, which was great. There have been some negative side effects, however. The dryness is most notable. Every morning (more so now than when I was on the med), dry throat, nose, EYES, skin. Also, there have been some new pimples showing up, which I'm getting totally scared about. My digestion is kind of funny as well, sometimes I'll feel extremely sick if I don't get water. All in all, I fully recommend accutane as a LAST RESORT because my skin did clear up remarkably (after months of dedication to the drug) Try other meds first, stick with them, be consistent, and DONT GIVE UP. Accutane is no miracle...it takes a confident person who's willing to make a lifestyle change. F 24 11 days
1/21/2007
 2  Presistant Acne Horrible itchy rash! Not worth having my face clear up to have a horrible rash over my body. Extreme fatigue some days. Inital stomach problems. Mild dry lips. I stopped the medicine once I developed the rash. I cannot see this medicine as being good for your insides if you develop a rash all over, cannot imagine what it is doing to me where I cannot see it! F 24 40 days
1/19/2007
 5  Cystic Acne Dry skin :) Dry Lips, Peeling ears and scalp, inability to wear earings at the present time, Tired, not depressed but more fatigued and apathetic than usual. I have to say I am more irritable, fell overwhelmed easier, and have lost my patience a couple of times at work, things just seem to get on my nerves more. Usually I am very easygoing. Oh and "night vision" problems..not difficulty seeing so much as lights on signs and headlights seem increadibly bright and drownd the road out. Seems to be working great; month 3 completly clear, month four I have broken out on my chin again, but healing faster than expected. Skin is dry which is a wonderful change, and I dont have to wash my hair every 12 hours. I just hope that it does not all come back full force when I stop. Also be sure your doctor and pharmacist are awear of the Ipledge program, if they are not very farmiliar with it it's a pain, doctors forget to ok you to anwser your questions, pharmacy looses your I pledge card, you can't rely on them to keep things straight. F 27 4 months
1/16/2007
 1  severe acne severe hair loss stunted growth nose bleeds extremely chapped lips My son was on Accutane for a 5 month stint. We were concerned about potential scarring both physically and mentally. We were mainly worried about the possible depression side effects. My son assured me that he still wanted to go thru with it. We had no insurance and at the cost of about $2500 for treatments I decided to carry medical thru my work. The medicine worked well overall (as far as reducing severe acne.) He has been off of it for over 2 years and his acne has been greatly reduced. But he now has extreme hair loss that has never grown back! He has the hairline of a middle aged man! He also has not grown 1 single inch since he took the drug!! At 18 he is 5'7" the same height that he was at age 15! It is very devastating! The dermatologist said that these side effects were not from the drug! B.S.! BE VERY INFORMED BEFORE YOU TAKE THIS DRUG! M 15 5 months
1/8/2007
 5  Acne Accutane completely cleared y acne within a few months. I experienced dryness nosebleeds and sore joints, but they were mild and the side effects are so worth it. i'm not done with accutane yet. i still have 4 weeks to go. hopefully the acne won't come back. M 20 20 weeks
1/5/2007
 3  Cystic Acne for 30 YEARS Dry lips; some dryness to face; dry scalp; joint pain; emotional sensitivity. Started at 20 mg 1st month; 40 mg 2nd month; 60 mg 3rd month and progressed now to 80 mg 4th month. I'm 5'7" & weigh 135#s. I was bumped up in dosage because my skin was still oily. Still get a cyst now & then, but they only last about 5 days instead of weeks. Major side effect is JOINT PAIN which I never had before, including hips, shoulders, neck, legs & feet. I move like I'm 75 - slow and heavy. Another side effect is emotional sensitivity. YES, this drug does cause emotional upset. The best way to describe is PMS 24/7 (nothing too serious, just don't look at me cross-eyed ;) My main concern is Joint Pain. Why? And will it go away????? Can anybody tell me. . . F 43 3.5 days
1/1/2007
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 3  Cystic Acne for 30 YEARS Dry lips; some dryness to face; dry scalp; joint pain; emotional sensitivity. Started at 20 mg 1st month; 40 mg 2nd month; 60 mg 3rd month and progressed now to 80 mg 4th month. I'm 5'7" & weigh 135#s. I was bumped up in dosage because my skin was still oily. Still get a cyst now & then, but they only last about 5 days instead of weeks. Major side effect is JOINT PAIN which I never had before, including hips, shoulders, neck, legs & feet. I move like I'm 75 - slow and heavy. Another side effect is emotional sensitivity. YES, this drug does cause emotional upset. The best way to describe is PMS 24/7 (nothing too serious, just don't look at me cross-eyed ;) My main concern is Joint Pain. Why? And will it go away????? Can anybody tell me. . . F 43 3.5 days
1/1/2007
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 5  bad acne Dry lips, dry all over. ACCUTANE DOES NOT CAUSE DEPRESSION. Anyone saying otherwise is trying to blame their problems on this miracle pill - stop being weak minded and take responsibility for yourself! There is NO scientific evidence showing a relationship between the two, and science doesn't lie (but people do). F 22 5 months
12/28/2006
 3  Cystic Acne Dry lips, eyes, dry earwax, increase in acne, mood changes, crying spells. I got angular cheilitis on the corner of my mouth, depression, and my acne has gotten much worse...but I am hoping it will get better since I'm only in the third month. F 25 3 months
12/28/2006
 5  acne sore anus...Muscle aches toe & joint pain Does anyone have a sore anus...please tell me what helps this...i use diaper rash cream & polysporin....But does not seem to help.... F 42 4 weeks
12/19/2006
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 5  adult acne & purigo nodularis headaches at 1st...slightly dry lips...Muscle aches & toe joints...back & hop pain... it seems to be working..But i feel extremely fatigue & my body aches & it hurts to bend down & up...Will this improve or get worse???? F 42 4 weeks
12/19/2006
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 3  acne dry lips and face. Got a cold sore on th 18th day. Anyone else get one?? 25 20 days
12/18/2006
 5  cystic & mod acne & excessive oil dry lips, nosebleeds (not often), dry skin, vaginal dryness... that's it! This cleared me 100%. If you have bad or cystic acne, please consider accutane! You will not be dissapointed. Don't believe all the hype about mental side effects - they are not true! Millions have taken this drug and been cleared, so can you! F 27 180 days
12/17/2006
 5  moderate acne dry lips, back pain, joint pain, dry, itchy skin, hair loss Be patient. This drug was awful to take for the first 2 months because i recieved no results other then dry dry skin. But now my skin is absolutely beautiful. Don't give up on it, and don't be afraid of the stories you hear about it. :) F 16 4 days
12/16/2006
 3  Severe Scaring Acne Chest/Back/Face I took this back in my late Teen years. I am 33 now. Around age 31 I began experiencing palpitations of heart. I am a marathon runner, no palpitation history in my family, so kinda a weird deal that I get it late in life.. It may have been the accutane, especially because I see other folks are reporting that. Other minor long term: I experience extremely dry skin during winter months. I must shower with a special soap or I have painful dryness. Accurate did clear my acne.. and I did have it bad. People talk about the emotional and depression part of Accutane.. I did not experience anything related to that. The huge open acne wounds were a pretty depressing thing, so it doesn't surprise me that folks who take it show a higher rate of depression over normal folks, they're depressed from their acne, not the drug. If I die from a heart attack or condition associated with the palpitations.. then obviously, accutane wasn't worth it.. its a pretty scary thing to live with heart palpitations, you slowly get used to them, but you never know when it might need a jumpstart.. M 33 1 years
12/15/2006
 5  moderate cystic acne dry scalp, chapped lips (mild), slight facial rash, headaches, fatigue (extreme at times), trouble concentrating, crying spells, anxiety, weight loss, mild hair loss, daydreaming. This drug has worked wonders for me! All of my acne is completely cleared (after about 3 weeks) and I have not had any further breakouts. I am able to deal with the side effects pretty well but the variable moods are challenging. I get anxious or depressed about things that generally I wouldn't even give a second thought to. Use this as a last resort as your lifestyle will be altered by the drug (may have to watch diet and alcohol intake). F 23 2 days
12/14/2006
 5  Severe acne While actively taking the medication, I experienced very dry lips, very dry skin in general, some fatigue. I can honestly say that this drug saved my life. Before Accutane, I had severe, cystic acne on my face( not really elsewhere) and was anxious at the thought of socializing with anyone outside of my family for even a few minutes. I also had fleeting thoughts of suicide on several occasions because it felt like a hopeless situation that I had no control over. Its not like obesity because you can control that. Severe acne came to dominate my every thought when I was outside of the house. I first tried all the topical treatments like Oxy(what a joke) because I really didn't know what worked. Then I tried Retin-A which I hear is a decent product but it really isn't meant for SEVERE ACNE. It was at that point that I decided to take the step and try Accutane because I heard from some high school classmates that it worked for them and I really had to try something, ANYTHING, to get rid of this crap that was on my face and ruining my life. Well, long store short, I love the results even th M 29 4 months
12/12/2006
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