ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Severe acne Extremely dry lips, Crusty nose but no bleeds, severe back pain, long-lasting headaches, reduced night vision, loss of hearing, lots of fatigue, joint pain, overall dry skin, mood swings, crying spells, weird earwax The dry lips started after about 5 days, the back pain was really bad when i got into bed at nite but faded after 15 minutes... So far, I havent gotten any new blemishes. slowly its clearing up.... I really cant handle the side effects tho... sumtimes so bad i had to stay in bed.. F 17 4 weeks
9/26/2006
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 3  scarring acne on face, back, chest Migraine headaches! dry lips, dry eyes, extremely sensitive skin, joint pain, changes in hearing I was only on brand name accutane at 60mg a day for two days. About an hour after taking the first dose I developed a headache. Pain relievers did not help it. After two days on the drug my headache was so painful I was in tears. Light affected me and any noise seemed extremely loud and hurt my ears. My joints ached when I moved. My skin was so sensitive and my body so dehydrated that if I clutched anything tightly in my hand, the imprint of it stayed on my hand for an hour later. It hurt to open a water bottle. I stopped taking the drug and my doctor told me I had had a migraine. I have never had a migraine before in my life and my family has no history of it. It was extremely painful and I may not be able to take the drug, even on a lower dosage. I did notice immediate improvement in my pimples, which shrunk in size. I guess this drug just wasn't for me. It causes different side effects in everyone who takes it and it may cause side effects not listed. So beware of what it's doing to F 21 2 days
9/20/2006
 1  mild acne HAIR LOSS,HAIR LOSS,HAIR LOSS!!dry mouth,lips,nose,face,rash on hands,HORRIBLE lower BACK PAIN! PAINFUL SEX, FREQUENT URINATION,sensitive skin,weight loss,insomnia,more energy,blurred night vision I DO NOT RECOMMEND THIS MEDICATION UNLESS YOU HAVE SEVERE ACNE, WHICH I DID NOT. MY HAIR WAS FALLING OUT EVERYWHERE. I STOPPED ACCUTANE 1 1/2 YRS AGO AND MY HAIR IS STILL FALLING OUT AND IS EXTREMELY THIN!! IT HASN'T GROWN BACK AND I DON'T THINK IT EVER WILL. I STILL HAVE FREQUENT URINATION WHICH WAKES ME UP ABOUT 3-4 TIMES A NIGHT... ACCUTANE IS A VERY DANGEROUS DRUG AND SHOULD BE USED WITH CARE F 23 5 months
9/14/2006
 2  pretty face, bad acne. SUPER dry lips and nose, rash on hands and arms, easily broken skin, and my biggest complaint- inability to concentrate at all!!! this means conversations, tv, and school. and i cant remember anything! scary feeling of not being able to think (about anything). extremely tired all the time. used aquaphor on my lips literally every 10 minutes (best moisturizer of all 6 that i tried) and could not smile, talk normally, or laugh bc they would bleed. (my food had to be the size of a dime or smaller). i am in grad school and was unable to concentrate on anything! i had no idea how to focus, it's all fuzzy and uncomprehensible. i couldn't even understand what people were saying when they were speaking to me. i just stared off into space and couldn't grasp reality -same with tv. it's SUPER scary and makes you think you are losing your mind- SERIOUSLY! and my acne worsened and left scars bc of this drug, not to mention the ones from rash and broken skin. sacrifice ur vanity (even if ur acne is terrible) for peace of mind. i'm crossing my fingers these side effects dont last... F 23 60 days
9/6/2006
 4  Acne Slight dryness of skin Acne cleared up at a decent rate when all other methods do not seem to work. M 16 16 weeks
9/3/2006
 5  Mild/Moderate acne very dry lips, dry skin, flaking skin, flailing and dry hair, crusty nose (from bleeds), back pain, and temporary ringing in ears in 1st month---all these side effects were ok to deal with This sh*t really is a miracle. I can honestly say that it was like this drug removed a "mask" from my face to reveal my true face. When I started on this drug, I was at the lowest point of my life. I quit school because of the acne problem, tried everything else available, and had enough. I thought, whatever the side-effects of Accutane, I don't care. So, I took the drug and was quite disappointed in the first month. My skin was flaky, dry, and horribly itchy. I had thoughts of suicide at the time, but quickly realized it was probably the drug at work and set those thoughts aside. The girl I'm in love with (we're only friends yet) started getting irritated at me while I was on the drug, presumably because the drug caused mood swings. BUT...here's the good part. I think for anyone who really hates their life because of acne, like I did, Accutane is THE answer. After about 4 months, the girl that I like said "Wow, you look really different, your pretty hot". So that d M 18 4 months
9/1/2006
 5  Mild/Moderate acne continued from below (18 y/o for 4 months) (continued...) So that did it for me, that's why I'm rating this a 5 lol. But anyway, after about 4 months I was taken off the drug and my face is almost completely perfect. I used to have the really deep-rooted acne, as in reddened skin and almost a mask of ugliness lol. Now my skin is exfoliated and shimmering, it's beautiful. This drug is a miracle and I would recommend it to anyone. Although I had a few side effects, I can honestly say I would rather have the side effects for the rest of my life than to have acne. Get Accutane! M 18 4 months
9/1/2006
 5  Mild/Moderate acne very dry lips, dry skin, flaking skin, flailing and dry hair, crusty nose (from bleeds), back pain, and temporary ringing in ears in 1st month---all these side effects were ok to deal with This sh*t really is a miracle. I can honestly say that it was like this drug removed a "mask" from my face to reveal my true face. When I started on this drug, I was at the lowest point of my life. I quit school because of the acne problem, tried everything else available, and had enough. I thought, whatever the side-effects of Accutane, I don't care. So, I took the drug and was quite disappointed in the first month. My skin was flaky, dry, and horribly itchy. I had thoughts of suicide at the time, but quickly realized it was probably the drug at work and set those thoughts aside. The girl I'm in love with (we're only friends yet) started getting irritated at me while I was on the drug, presumably because the drug caused mood swings. BUT...here's the good part. I think for anyone who really hates their life because of acne, like I did, Accutane is THE answer. After about 4 months, the girl that I like said "Wow, you look really different, your pretty hot". So that d M 18 4 months
9/1/2006
 5  cystic ance Very few side effects. moisturized with the best stuff I could get and stayed out of the sun! Terrified to get pregnant, though. 100% chance of Birth defects!! After years of acne "volcanos", antibiotics (and Yeast infections), and cortizone shots in my face I'm finally free!! F 33 4 months
8/31/2006
 4  Acne that created scars 1- Severe Chapped lips, The only brand that helped what Chapstick. 2- Nose dryness, and occassional bleeding, I applied liquid glycerin once in every two days. 3- Face dryness, treated by moisturizer 4- face sensitiviy to sun (sunblock). 5- dry patches, and small rash spots on my arms. 6- loss of tastes. 7- Minimal back pain. 8- Eye Dryness ( used artificial tears). I wish I had experienced some weight loss as some people have ;) 8- Dry hair. Supposidly this is my last month (th 5th), but till now I am not 100% satisfied with the texture of my skin. I have lost all acne expect for one huge under the skin bump, that is not going away. My skin doesn't look as smooth as I thought it would. Still not comfortable taking close-up pictures. F 23 5 months
8/29/2006
 3  Acne Dry face(flaking), severly chapped lips, dry scalp and hair loss, lower back pain, dry nasal passages. The face-flaking isn't really a big deal. It's just a bit annoying since I wear make-up and you can really see my dry skin. I've just been putting a mild lotion on everytime I get out of the shower and when I wake up in the morning. My lips kill. They peel and crack and just loathe me. Chapstick has become my new best friend since I've been taking Accutane. My scalp has become dry and flaky. I just wash it with just conditioner everytime I shower instead of shampoo. Conditoner still has alcohol in it so it still somewhat cleans your hair, but doesn't dry your hair out as much. My hair has beenn falling out a lot too. But that's not really a big deal to me. My lower back gets sore not when I'm active, but when I lay down and rest. It doesn't last long and it's a good excuse to have your friends massage your back. The only time I had a nose bleed was when I was sick and was blowing my nose a lot. Other than that, my nose hasn't really given me any problems. I keep some nasal spray in F 16 3.5 weeks
8/25/2006
 5  Cystic Acne Cracked and bleeding lips, dandruff, dry skin, involuntary weight loss. I was 16 when I started and didn't take very good care of my side effects (didn't use much lip balm, conditioner or moisterizer), so most of it could have been avoided. I did lose weight like crazy, and ate everything I could get my hands on without any gaining effect. That was pretty neat, but I hear it's rare. F 17 6 months
8/21/2006
 4  cystic acne decreased and blurred vision, extremely chapped/dry lips, moodiness, overly dry sinuses, PAINFUL back, shoulder, and joint aches in the morning, bouts of depression, lost of interest in daily activities... In terms of acne breakouts, i responded quickly to the Accutane, i experienced the usual "drying out" and that was not so bad, up until the 5th month of treatment where I began to wake-up with insanely painful aches in my joints, back and shoulders. I felt and feel like an elderly person. That's why I am here- trying to see what side effects others have felt. I realize everyone reacts differently, I just hope the joint pain goes away after my treatment... Good luck to everyone out there. Acne is something I wish none of us had to deal with. Instead of a trust fund, I inherited bad acne. Go figure. M 26 5 months
8/16/2006
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 4  Severe Adult Acne Extremely dry skin. Dry lips, dry cracked lining of nose (but no bleeding) EXTREME PAIN!!!! After I had my second child, I developed severe acne. Huge cysts all over my face. I actually had someone ask me if I had the chickenpox. I never looked anyone in the face I was so embarrassed. I was on Minocyn (Antibiotics) for about four years and then they just stopped working. Accutane was my last option. Being a brittle diabetic, this wasn't the best option for me but I didn't know what else to do. My acne got much, much worse when I first started, but I knew to expect that as my doctor went over all of the side effect with me. My acne cleared up comepletely. I haven't had a pimple since I stopped taking it. The pain however, is unbearable. I can't move my neck to either side, I can't rotate my left hip outward and my left arm is completely useless. I can't even dress myself anymore. I can't put my hair up anymore(and it's extremely long). When I say I have pain, I don't mean it kinda hurts, I mean it's excrutiating. It limits me in every thing I do. I can't go to F 30 5 months
8/15/2006
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 4  acne I have been off of Accutane for almost 6 years now...During and after taking Accutane, I experienced a serious loss of vision which has turned out to be permanent and is getting worse. My acne became seriously worse for a long time before it got better. I developed and still have digestive problems and urinary problems, but the urinary problems may have been from before. The texture of my hair changed; my hair went from thick and straight to very thin and curly. It didn't change back until after I stopped taking Accutane. I did get slightly depressed, but I do not contribute it to the Accutane. I think I was upset that the medicine wasn't working as I had hoped. BUT...today, my skin is clear as a baby's butt, and I couldn't be happier....except for the side effects I am STILL experiencing. F 22 2 years
8/11/2006
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 1  20 years of acne severe dryness of skin (but the acne still manages to continue), severe dryness of eyes (still have that problem, depression (on and off), migraines I do not recommend this med after two rounds of it. It worked short term for me, then the acne came back after about a year or so. Try chemical peels from a dermatologist's office along with the other meds they offer. The peels actually have helped the most of all. F 38 6 months
8/9/2006
 2  Acne I took this drug several years ago and ever since I've been having problems with my prolactin levels which never happened before I took this drug. I think it has something to do with Accutane but I haven't found it stated as a side effect by other people. F 35 4 months
8/4/2006
 1  severe cystic acne reddness all over...my lips peeled off by the layers...night blindness it was misery!!!several people i knew including my brother that needed help refused to take it after they saw what it did to me.. the 1st time i took acutane i was 14 years old an it was still experimental and i took it a second time about 3 years later when i was about 17...im now 37..and have had no relief...i continue to suffer F 37 2 times
8/4/2006
 4  acne Dry Lips, Vaginal dryness, decrease in sexual arousement, dry eyes My acne cleared up excellent, was it worth it, yes. I have to say my acne did come back after using accutane for 1 year. i will be starting it again soon. I have tried everthing in the book and nothing helped except accutane. F 25 1 months
7/27/2006
 4  acne seeing thing that wernt there(not to bad) found things i liked boring loss of appite weight loss. ate alot of jelly beans :) i had had acne sence i was about 12 my mom told me it was because of my hair (at the time i had cornrows down to my sholders) and that there was always dirt and stuff on my face so i cut it off and the acne dident go away so i tried many diffrent products which helped but as soon as i stopped using it it came back so the last resort was accutane and it showed some major imrovment after about 15 pills tho i did lose 10 pound after the 15 pills but i plan to out it back on. recomented to anyone whos willing to push it to the limit M 15 4 months
7/27/2006

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