ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Stubborn Acne Dry skin (especially my nose) and lips. Vaginal discomfort. Fatigue I have experienced some vaginal discomfort while on this medicine. I havent heard it discussed before so I thought I'd mention it. F 16 1 days
10/30/2007
 5  moderate acne that wouldn't go away dry lips, skin, and hair, hip, ankle and back pain, weird appetite, weight gain (15 lbs), hair shed like crazy, but no visible difference in volume, slight moodiness, whole face was very pink, really bad breakout first 2 months I've been on prescription medication for my acne since I was 8 years old. I tried all the most popular medicines, including Differin, Benzaclin, Proactiv, and RetinA, as well as over a year of antibiotics but skin would just NOT CLEAR UP! My skin wasn't REALLY bad until I was about 13 though, and then I was shy and anti-social because i was very self conscious. My mother wouldn't let me go on accutane because she was terrified of all the side effects of depression and suicidal thoughts. Finally after seeing my scaring get worse and worse, my doctor convinced her to let me try it. While taking Accutane, I was slightly more moody, but not depressed.My lips were soooo dry! I definately reccomend aquaphor or a prescription lip balm. My skin was very dry, but nothing I couldn't handle with a combination of regular moisturizer and occasional cortisone cream for really dry patches. My hair got drier, but it made it perfect because it was greasy before and now i can go 2 whole days with my hai F 15 6 months
10/24/2007
 3  Acne (Adult acne) Sex drive is nada (watch out!!), dry lips I left a comment on September 9th (about 2 comments before this one) and would like to update. I have been on Accutane now for roughly 6 months. For the last 2 months, I've been on 80mg and 40mg, every-other day. Since then, my sex drive has basically left me. On top of that, I have gained weight since taking Accutane. About 15 pounds infact. I'm going to the doctors in a few days and just may stop Accutane. I'm really not satisfied with it. But, I just wanted to warn some about the possibility of sexual side-effects. F 24 6 months
10/23/2007
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 5  Acne I think this is the best drug! A miracle! I took a cycle of it and though I did have dry skin and cracked lips, it really improved my skin dramatically. I took 40 MG / day for 10 months. Some blemishes did return after stopping but not the cysts. I'm a 33 year old woman. People think Accutane should be off the market because it causes birth defects. Do not avoid taking it because it causes birth defects. Just don't get pregnant on it!!! Pretty simple. F 33 10 months
10/20/2007
 4   Dry lips and skin I am having to repeat the course because my acne has returned. F 18 4 months
10/20/2007
 5  accutane dry lips, nose, and skin. Sore muscles and fatigue. Painful sex F 24 5 months
10/17/2007
 1  Mild persistent Acne Permanent Dryness! All over skin Dryness on scalp, body, lips, hands, feet, etc. Permanent Hair Loss and continued Rectal bleeding. Depression, anxiety, heart palpitations. I am 33 years old. I took this drug when I was 18 or 19. I've had these "side effects" ever since. My skin immediately & permanently changed tone and texture. I had naturally tanned skin, know permantely "lighter" & doesn't tan anymore. I burn easily now. I have very little natural skin oils left. My hair changed texture. Used to be thick and beautiful, now is thin, brittle and whispy. The hair loss continues to this day. At 33, I have very thin whispy hair. It has aged me prematurely. The skins natural oils are permantely reduced by Accutane. This is what keeps your skin YOUNG! As we naturally age, our skin losses its oils. DON'T TRADE SHORT TERM GAIN 4 LONG TERM PROBLEMS! THIS DRUG IS TOO STRONG FOR MOST CASES! BAD, BAD, BAD! After reading all the posts, It's comforting to hear I'm not the only one who suffers from continued ACCUTANE "side effects". I thought for a long time it was just bad genes, poor health, Depression etc. I now know its from this FREAKIN DRUG I took when I was too naive to understand the potential consequences! We all want quick fixes, there's no such thing! WAKE UP! and stay away from this DRUG! ITS BAD NEWS for vulnerable teens looking for a way to end the traumatic effects of ACNE. THIS JUST TRADES one affliction for many! PERMANENTLY... M 33 6 months
10/15/2007
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 3  Mild but persistant acne Bloody nose, dry lips, flaky skin, lower back pain (not sure if from accutane), occasional testicular pain/weird urination/mucous in urine, slight loss of sex drive, pus in eyes. It got rid of my blackheads and I never felt depressed, which is good. However, I'm paranoid now that something may become wrong with me in the future and I have these strange urinary symptoms (though doc said not to worry)! M 17 5 months
10/14/2007
 1  Acne treatment Crohn's disease, irreversible gastro side effects. NO Bullshlt guys, I took Accutane in 1996-97 and am currently suffering from Crohn's disease since 1997. Not 100% sure that Accutane caused what I have but after all these court cases (which I am about to join with) showed they knew it caused IBS problems, I have to say it's an evident possbility. Just to let you know, it did work temporarily to clean the acne up. BEWARE Fellas and good luck. M 25 1 years
10/13/2007
 2  Cystic Acne Severely dry skin & depression Has anyone experienced excessive sleeping problems? It's been seven years since I have taken this drug, and I seem to be going in circles. Any help would be greatly appreciated! M 21 6 months
9/26/2007
 4  Acne dry cracked lips, bloated feeling in stomach area, weight gain (15 lbs.!!), hair falling out, dryer face than normal (but manageable), muscles sometimes ache, back sometimes aches, dry nostrils, dry eyes Sounds like a lot of side effects, but so far it's been worth it. My face is clearing up, although slightly dry. I noticed that the tone of my face is much better and more all one color rather than blotchy. Along with using Accutane, I also spot-treat any pimples that come up. I use Murad's Acne Spot Treatment (comes in a little tube)...I higly reccomend this because it seems to speed up the whole process of getting rid of it. The one thing that kinda upset me is that I gained roughly 15 pounds while I've been using this for the past 4 months. And I've NEVER gained like this before..not when I was a teen, and not even the Freshman 15! Accutane is the oly thing that I can come up with. Not only have I gained weight, but my stomach/bowels (I don't know..) feel bloated...not a great feeling. So, overall..the two things that stick out most in my mind are the weight gain and dry, cracked lips. BUT.....my acne is better and will hopefully continue like this... F 24 4 days
9/8/2007
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 2  Acne, Oily Skin Scarring, Dry Skin, Dry Lips, Dry Hair, Thined Skin I took Accutane at age 19 and didn't expect the side effects to be so severe. The first two weeks my skin cleared up and looked beautiful. About a month into it I developed minor acne but it never healed properly and quickly scarred. I had red scars and indentations, in my face and back, which I never **ever** had before. After three months my skin was permanently changed for the worse. It doesn't tan anymore, it just burns. I have to use soap and shampoo without "sulfates" or I will get severely dry skin, hair and lips (never happened before). Actually my skin didn't sweat or perspire for at least a year after I stopped taking Accutane. My once tough and thick skin seems much weaker now and is more susceptible to cuts and punctures. I'm not a fan of Accutane. I feel it un-naturally changes your skin for the worse by prematurely aging your skin (why do that?). I used 4 types of prescription medication before Accutane and none of them had nearly the short term or long term sid M 27 4 months
9/8/2007
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 1  Cystic Acne Irritable Bowel Syndrome, Severe Anxiety, Social Phobia, Headaches, Dry lips & Skin, Aching Joints, Muscles & Bones, Fatigue, Insomnia, Severe Depression, Short & Long term memory loss, SEVERE Concentration Problems, Hair Loss, Sexual Dysfunction. Some may call this the miracle drug, at the age of 15 when I took a 6 month course of roaccutane I thought this was my miracle cure as it cleared my skin completely. Little did I know what would come in the following years. I am now 23 years of age turning 24 and this drug has COMPLETELY RUINED MY LIFE. I am unable to work anymore and have severe problems in social situations due to all the adverse side effects that are STILL in my body after taking this drug nearly 9 years ago. My ability to concentrate is getting worse by the year as well as my memory; I'm constantly unable to remember the smallest mundane things to even the largest. If I had the choice now I would of preferred to keep my acne and deal with it. My advice to anyone contemplating taking this drug, if you want your life COMPLETELY AND UTTERLLY RUINED then by all means take it, but to this day taking this drug is the biggest regret, and always will be the biggest regret of my life. DO NOT TAKE ACCUTANE!!!!! I WOULD M 23 6 months
8/21/2007
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 5  severe cystic acne dry skin, eyes, lips I loved it. I'm normally extremely oily. i enjoyed not having to dab my face all day to keep the shine at bay. my makeup looked great all day. not sliding off with the oil. tho i had to moisturize my lips constantly, the rest of my body was not as dry. i started using a moisturizer for dry skin and that took care of the dryness on my face. i have finished taking accutane and my skin still looks good. back to using a moisturizer for oily skin. F 48 4 months
8/17/2007
 4  Cystic Acne Dry Skin, cracked nostril membranes, cracked dry lips I have completed my accutane treatment and am happy with the results (so far). Along the way I had to come up with some treatments for my side effects that I would like to share. For my chapped lips I found Lip Vitamins to be the best. It is not waxy like many others and really help prevent the cracking. For my face, used Jasmine & Aloe Vera Gentle Moisturizing Gel from Serindipity-Doo It is lighter than regular aloe vera gels and a little lasted between face washes. I had experienced flaky dry skin all over my face and neck. My symptoms were not noticable except after washing my face. For my nose I liked Nasal Comfort http://www.nasalcomfort.com/. It was not a cure but it helped alleviate the discomfort quite a bit. M 40 6 months
8/13/2007
 1  Cystic acne Ulcerative Colitis Developed colitis 3 years after taking Accutane, and I'm 90% sure it's from the drug--even though I was taking a pretty low dose (20mg) for a short time (4 months). Also, cystic acne returned within 5 years. Taking this drug is NOT WORTH the potential long term side effects which now, for me, includes the possibility of loosing my colon and the increased risk of colon cancer. F 26 4 months
8/10/2007
 4  Acne, what else? dry lips and dry skin are a given, chap stick and moisturizer will be your new best frends I'm fairly confident some of the aformentioned complaints should not be attributed to Accutane. I didn't experience depressive feelings any more so than I did before treatment, nor any libido changes (where the hell did that come from by the way). For those of you comtemplating Accutane, I'd go for it if your skin is bad. Perhaps, it is better to take during the Summer, although sun avoidance could be very disconcerting. The cold weather and Accutane don't mesh well, however. M 23 21 weeks
8/3/2007
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 5  persistant acne... nothing helped dry eyes, achy joints and dry lips I am a medical student... 23 years old and have been dealing with acne since I was 17. Nothing worked, I was on antibiotics, spirlactone, duac, retin-A, proactive, benzoyl peroxide... you name it. My acne was not that bad... just consistent. I began to get tiny little scars, and thought about how much I was spending on finding a treatment. After my first year of medical school, and learning about accutane I decided to try it. (I am super health conscious, and really concerned about my liver.) I began to talk to some peers in my class who did accutane and had incredible results. I did not hear from any of my classmates that they regreted their decision. That was importnat to me, because all of them are very aware of the side effects, and how harsh it can be on the liver. Just know that your doctor will be monitoring your liver during your treatment. If anything is ever out of range your physician will take the necessary precautions. I am finishing my last month, and cannot believe the F 23 6 months
8/2/2007
 1  acne Extremely dry lips, nosebleeds, return of acne once off of medication, hair loss I took accutane 15 years ago, and continue to suffer from hair loss which I believe was caused by this drug. Also, the acne I had came back after I stopped treatment. So much for the "miracle" cure. A couple of years ago I found out acupuncture can treat acne, and it helped enormously. I highly recommend it. F 32 3 months
8/2/2007
 3  acne i had a rash on the back of my hands and arms during the winter months. it left my lips and nose very dry and I would get severe nose bleeds all the time. Also, while i was on it, my period seemed to disappear. It dried my skin up as well. It has been a year and a half since i took this and I feel pretty satisfied. the acne is not nearly as bad as it used to be, although it still flares up when my period comes. it has left my nasal membranes, lips, and eyes pretty dry, but my skin is still oily, like before. after getting off of it, my period returned to a normal cycle. the rash went away as well. F 17 6 months
8/1/2007

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