ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Moderate Acne Severe dry eyes which causes very blurry vision, chapped lips, very mild depression, tiredness, thinning hair, slight joint pains. I've had acne for over 10 years and became immune to most antibiotics so Accutane was my last resort. I'm in the final month of my 6 month treatment and really didn't start noticing the side-effects until month 4. None are very bothersome except for the blurry vision because I snowboard and need to have excellent vision. But my skin looks perfect now! All in all, 2 months of side effects is worth ending a decade of acne. F 23 6 months
2/9/2009
 2  acne dry skin and lips, SEVERE tiredness (felt like I was asleep the entire 5 months I was on it), back pain that I still experience today though it's not THAT bad, its still bad. Caused a huge breakout which caused scarring. I had no scars before taking this, but now I do. I was on accutane about 5 years ago. It helped my skin, but I look different. Like it dried me up. Also had some SEVERE anxiety a whole year AFTER taking accutane. Thank god it went away. It was debilitating and messed up my life for a good amount of time. I would never, ever, take this again. M 23 5 months
2/5/2009
 1  Severe acne Severe neck and back pain, joint pain, arthritis, loss of movement I started taking these pills just three days ago, and immediately after I started taking them, I got really strong pains in my neck. I've never experienced pain so bad in my joints before. I have lost all movement in my neck, and have been unable to preform most tasks at my work. I thought that maybe I was sleeping wrong, but after consulting a nurse (who informed me that a matress, no matter how hard, could never creating this painful and lasting joint problems) and several websites, I put two and two together to blame Accutane for my loss of movement. F 21 3 days
2/3/2009
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 1  cystic acne SEVERE and PERMANENT BACK and JOINT PAIN! Thinning hair and poor vision. This drug has ruined my life! I took it at age 30 and was healthy before beginning it. 3 months later, the severe pain came in my back and EVERY joint in my body! My hair thinned, and my eyesight became worse. I have also noticed my skin looks older, no doubt because of the lack of oil needed to stay looking young. It is now 8 years later, and I am unable to work full-time and have to lie down or rest frequently throughout the day. I am with the other person about a class action law suit. This drug has no business on the market! F 38 3 months
1/28/2009
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 4  Acne Overall this is great! ive been on it for almost two months now and its dried me out great! Chapped lips; Back Pain; exzema type rashes on my forearms and on the top of my hands and knuckles. Shaving has become difficult. Now it just plain out hurts. So far i highly suggest this. Im sixteen years old and So far its done more good than bad. My arms do look funny from the rash; so thank god its winter! long sleeves are a blessing ahahha. When i wake in the morning; I get these dried patches of blood in my nose which is very gross; and when you blow your nose or scratch at them; they peel off; taking some of your skin with it so you have a sore in your nose; and this repeats nightly. No moisturising Nasal spray has helped. But its nothing horrible. No depression. Just aches in my back; hip and legs. Sitting for long period of time becomes difficult. F 16 2 months
1/27/2009
 5  severe acne While taking accutane i experienced many side effects. Severe scalp itch, to the point of getting a medication for that. my skin was so dry that i had to get a prescription lotion. Also the biggest thing is my sore achy joints. every single joint in my body hurt to the point that i had to sit out on any physucal activity. i was in middle school and could not participate in any sports or P.E. years down the road i have developed degenerative disc disease and osteo arthritus. i am 22 years old now and i took high dosages when i was only 12 13 years old. i isuffer from depression and have sexual problems. my body constantly aches. It completely cleared my acne and worked amazingly. i dont even have to wash my face anymore and not have to worry about a single pimple. i took this drug at very high dosages like 120 mg/day for about 9 months M 22 9 months
1/15/2009
 3  acne I am feeling very uncomfortable. My back hurts and my joints ache. I am tired to the point of needing to take a nap everyday. I used to play in the yard with the kids and I feel like I have no energy to do that and I also have such bad muscle cramps that I am afraid to use them. No headaches- just bad aches and pains. The dry lips are tolerable. I am wondering if anyone else has this problem and how long it lasted. It seems like there is a range of symptoms associated with the drug. I am 41, have mild acne but tired of the scars it leaves. Should I preserver? I have been on it about three weeks- have a pretty good breakout currently, and hope it works in the long run to make it worth the pain it causes. F 41
1/8/2009
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 5  Cystic acne, painful, unseen bumps I was part of the trial for Accutane, before approval, so there was no cost for me, just forms and reports. I did have the usual dry skin, chapped lips, sensitivity to light and lots of body & joint pain. I also had a few headaches. Since I was in jr high I had acne.I tried creams, antibiotics, sunlamp treatments & had dr cutting open the bumps, leaving scars. So,when I was asked by a dr if i was interested trying this, I jumped at it. It's been so long, since my experience, 2 of my sons used it only 1 stayed w/it the other fainted at his monthly blood draw. so the one that stuck it out has great clear skin, with no breakouts, his brother is not as clear, but it's his choice. I am entering my golden years & haven't had a breakout in many, many years. just the self esteem makes it worth it! For me it was a miracle drug. I owuld do it al again if I needed to. F 55 12 months
1/3/2009
 1  Moderate Acne Vomiting, chapped skin, depression, weight loss.I was on Accutane for 5 months and did not see results during or after my treatment. I started at 80MG and then my doctor tried to up my dose to 120MG. (I weight 124LB.) My pharmacy refused to fill the 120MG dose because it was ILLEGAL?! The first 1.5 months of treatment the side effects were bareable. I had chapped skin and some stomach irritation but nothing dramatic. During the last 3.5 months of treatment my side effects escalated and were horrible. I had severe depression (never had ANY issues before). I cried everyday for no reason. I would just sit in bed and cry. I also could not eat. I was so sick that I would throw up water. I could barely take a sip without running to the bathroom. I lost 20 pounds. I actually told my doctor I was having depression and losing weight from feeling sick and SHE KEPT ME ON IT! Finally, I went off thinking I would be fine. WRONG. Now 5 months after the drug I still cannot eat properly. I have no more depression (thankfully!), but I still am extremely thin. I can only eat bread. If I eat ANYTHING else (meat, cheese, fruit) I am running to the bathroom. If anyone knows why this is happening, please post and let me know! Did accutane ruin my digestive system? I do F 24 5 months
12/28/2008
 4  Acne mild joint pain (on and off), chapped lips/skin (aquaphor for lips does miracles), a little bit of eczema in the beginning (hydrocortisone cream helped) Everyone will react differently from Accutane as I've read. Luckily for me it worked. I took it in 2005 for about 5 months and it cleared my acne, but a few months later it came back. Then this year 2008 I am taking it again and am going on month 4 and am already clear. People comment on how my skin is glowing. This is a first! I have two months left and I can't imagine how much better it's going to look. I love how I don't have oily skin anymore. I hope it doesn't come back but because of my success I wouldn't mind going on it again. Also, apparently this medicine is known to increase suicide rates. I've had depression since I was 11, and have been seeing a therapist(and reconnecting with God is helping too), and I've been on accutane and find myself happier because of my confidence! So, no depression troubles for me. F 21 5 months
12/27/2008
 4  Moderate cystic acne on face Severe headaches during the first 2 weeks,Nausea, joint and muscles ache, dryness, chapped lips, dry and itchy eyes and eylids So far, I think that the medicine is really helping. The headaches in the beginning were virtually unbearable. My dr. advised that I stop the medicine until they subsided, then reintroduce to my body at just half of the dosage for a few days. Worked wonderfully, now haven't had another headache. But, alot of muscle aches and pains. Feels like I work out everyday, and I don't. M 32 2 months
12/27/2008
 3  severe acne I am currently taking accutane right now, I been on it for about a month now and see a slight change. My derm. had put me on 30mg which I take 2x a day. on my first week of accutane I realized that my face didn't look as oily as it did, & it seemed as if my acne was clearing up. After about the first 2 weeks, I had gotten the initial breakout which sucked. After being on if for about a month I still get those occasional breakouts, but overall it looks as if its clearing up. As of right now I am experiencing the chapped lips, dry skin, and some back pain. I believe I'm gettin this back pain due to weight lifting since I go to the gym. My friends also tell me that I tend to have mood swings, which I haven't really noticed. I just hope this pill works, I want to be acne free already! F 17 1 months
12/25/2008
 1  Persistant adult acne Whilst on it; Occassional nosebleeds, mild muscle and joint pain that disappeared after a while, dry skin and lips, small patches of eczema, tiredness and sometimes a headache. The WORST drug ever created by man. I took a 7 month course of 40mg per day and whilst my experience on it was brilliant and fairly smoot sailing, 3 months after stopping all hell broke loose. I now deal with chronic, widespread dehabilitating joint pain, sexual dysfunction, IBS and generally feel more suicidal than ever before and this is 18 months on from my last tablet. It just isn't worth it. Yes my life improved dramatically at first and my skin cleared instantly and is relatively clear to this day, but god how I wish I could go back in time. I have ruined my life. I can no longer fulfill my ambition and it required strenuous physical activity and I doubt I can hold down a job for much longer too. This is an absolute evil drug and I URGE everyone to get off it ASAP. THE SIDE EFFECTS SOMETIMES HIT YOU AFTER TREATMENT HAS FINISHED DON'T FORGET!!!!!!!! M 26 7 months
12/22/2008
 5  facial acne just dry lips basically dry skin overall IT IS AMAZING. i took it for 8 months and it completely cleared me up. after ONE DAY i saw improvement. after one week it got a little worse, and then improved from then on. I have been off of it for 4 months and my acne is coming back so im going to go get it again because i LOVE IT. M 19 8 months
12/20/2008
 4   The only side effects were try lips that occasionally cracked at the corners. My dermatologist had to give me a cream to treat these sites that were eventually infected with yeast. Kinda gross, I know... I also had dry itchy skin all over my body. I constantly had to moisturize myself, particularly during the dry winter months. Accutane gave me the clear skin I've always wanted; I just wish I took it earlier because I used to be very embarrassed about my acne. When I turned 20 and still had adult acne, I decided I had to try something potent. I am glad accutane worked for me. F 23 6 months
12/18/2008
 5  Nodular Acne, Folliculitus Dry Skin and Chapped Lips I'm almost finished with my 3rd month of Accutane. Started with 80mg a day, up to 160mg per day. I weigh 240#, therefore, the heavier dose. I had recurring bouts with folliculitus, nodular acne on the back of my head/neck. After about 5 years of being on different antibiotics, my new dermatologist precribed Accutane. What a fantastic drug. It cleared up the problem within the 1st month. I will remain on the drug for the recommended 5 months. Doctor says, if I remain on for 5 months, the problem "may" never reoccur. M 50 3 months
12/15/2008
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 5  Severe Acne dry skin I love love love this medicine!! I took one cycle of it and it cured my acne. It is heavy duty but the difference is miraculous. I went from having such oily, nasty skin to having beautiful, clear skin that I get complimented on often. I highly recommend this medicine! Throw away all the creams and special face washes because you wont need them anymore... F 16 6 months
12/13/2008
 3  persistent moderate acne, keloids After a week, acne got much worse, but they say this is common. 2 weeks in, skin on face got very dry and chapped lips all the time. I was also more emotional. Got down easier. Also much more irritable to the point where I was on the verge of violence. I have never felt this way my whole life. Those raging emotions subsided after a week or 2. But I stopped after 4 weeks because I started to get a tightness in my chest. very mild but still worried me. Chest pain is not a common side effect so it could be completely unrelated. But i didn't want to take the chance. And plus I noticed it was thinning my hair. Was on 40 mg daily dosage. Was only on it for 4 wks and I only got maybe a few small breakouts in the last couple weeks. So it was definitely working. M 30 4 weeks
12/12/2008
 4  severe acne dry, cracked lips I was on accutane for 6 months about 2 years ago after suddenly developing severe acne at age 40. It certainly cleared the acne which erupted all over my face for no reason. However, I suspect that the knee pains and elevated cholesterol that I still have today was due to the drug. Both of these started after I was taking accutane. M 40 6 months
12/4/2008
 3  Cystic Acne Normal dryness (happens with everyone). Major head pressure which affected vision to the point I began to feel my eye sight was deteriorating. Constipation! Depression.. I have never felt so "blah" in my entire life and I never wanted to leave the house. The drug has already cleared up my skin in just 3 weeks, but I stopped due to the side effects. I feel as though it has made me slightly more depressed and not as happy. What is worst though is my eye sight. I stopped because I feel like my eye sight was declining. It might just be the side effects of the drug but I just don't want to take that chance. It also caused major brain pressure to the point where I couldn't concentrate at work. This stuff is intense and just monitor your side effects well when taking it. I'm never going on it again. It's not worth it to me. F 23 3 weeks
12/3/2008

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