ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  I had a dry skin and lips F 16 1 days
8/9/2013
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 1  Acne I took roaccutane 8 yrs ago and it destroyed my health. I had the usual side effects while on it but the worst side effects came in the year after finishing treatment. I developed lower back pack which has spread to every joint in my body, i have a chronic pain in neck, shoulders and knees. I have arthritis in all my fingers. My skin is constant dry, irritable and gets red very easily. I have constant dandruff. My hair and fingernails are extremely weak. Ive suffered a lot of hairloss. About 2 years after roaccutane i developed chronic ibs. My eyes are constantly dry and extremely sensetive to light. I also have frequent pressure headaches and erectile dysfunction. There is no doubt in my mind roaccutane caused or played a major roll in all of these problems. Roaccutane is a toxic chemo drug that is not worth a clear complexion. You have no idea how your body will react to poison. I thought it worked great right after taking it, boy was i wrong. Roacuutane is one the worst things a healthy young person could put in there body. Please DO NOT take it. M 25 6 months
60
7/30/2013
 5  Acne Slight headaches in the first month of treatment. Chapped lips. Dry sinuses. Hip & back pain (mild). This is my third month taking Accutane (out of eight) and it has already helped a significant amount. I was reading some of the reviews that are posted and I've come to the conclusion that I can't really base my opinions off of other peoples experiences because everyone is different and different things happen to different people while in treatment. If you have real bad acne or you aren't happy with your skin and nothing else worked.. I would definitely recommend this! F 18 3 months
40mg 1X day
6/27/2013
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 4  Acne Dry Skin/Lips/Nose Hand Rash Muscle and back pain Slight fatigue Headache Hair Thinning/loss Redness of face Dry eyes Sensitivity M 17 6 months
60
6/14/2013
 5  acne Dry skin but moisturizing helped, dry lips Vaseline lip care helped this, dry eyes occasionally sore achy muscles but not unbearable the only thing bad about this is I am a little more short tempered than before but I am on my last month and would recommend to anyone it works amazingly!!!! F 24 5 months
2x daily
5/1/2013
 5  severe acne Very dry lips and nose over all very dry Skin.full body itching dry couch ,mouth ulcers .mood swings.sore back. My 3rd time taking the medication this time side affects seem worse,but worth every minute of discomfort. As it truly is an amazing drug for acne,acne wasted so many years of mg life hidding a way or covering it up as good as i could with expensive makeup.knocked my confidence.however still not perfect but so much better and happier.so plzzzzz stick with it . F 28 5 days
40 mg 1X day
3/26/2013
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 1  Acne Accutane completely ruined my life, these are just a few of the permanent side effects i have- dry scalp, eyes, lips, sinuses and skin, pressure headaches, joint and muscle pain, severe back pain and severe depression. If you value your health stay well away from this poison. M 24 6 days
3/17/2013
 4  severe acne My son took this for 5 months when he was 19. No apparent side effects while taking it. Had to have a blood test every month to test his liver function before doctor would give the next month's refill. Acne is now completely gone. However, he has been experiencing anger outbursts (uncontrollable)for a while now. We have just started to think that this might be related to the Accutane. He is now 22 years old so it has been a while since he took the drug. This anger thing is very worrisome and we are looking into counseling for this. So far the Accutane worked wonders. This acne thing was terrible for my son and made him very depressed - had him always looking at himself in the mirror studying the outbreaks. M 22 5 months
40 2X day
3/13/2013
 1  folliculitis I was given accutane (amnesteem) for folliculitis that had failed to respond to all other treatments. My face was always very greasy, so the doctor felt that a low dose of accutane for a short period would cure it. Pro: Within 2 weeks my face cleared. I have been off the drug for two weeks (after a 6 week course) and no recurrence of the folliculits, but its a bit soon to tell if I'm "cured" or not. If I knew then what I know now, I would have stopped taking this drug as soon as I had the result I wanted. Con: My inner sense of well being was completely destroyed. I could not sit still without panicking. I lost the ability to be happy about anything or to sense any enjoyment or sense of well being at all. I have never in my life experienced the type of anxiety and depression that I experienced when on this drug. If I had knowledge of my experience before I took this drug, I would never have taken it at all. I want nothing to do with accutane at all. Howe I started taking the drug 11/5/12 last pill was 12/16/12. While taking the drug, I noticed that within 1-2 hours after taking it I would get very irritable, so I decided that I would take it about a 1/2 hour before bed, so that the aggression would express itself while I was sleeping. Within 2.5 - 3.5 weeks I started waking up in the middle of the night with a sense of utter despair and hopelessness. I'd tell myself it was just the drug and to shut up and go back to sleep. By 12/10, I wanted to stop taking it, but I had a Dr. appointment 12/17, so I kept taking the pills. The Doctor prescribed a different type of accutane to combat the depression.. The next morning, I woke up in a total panic at about 5:30 am. I went to the fridge and drank a lot of water and then laid back down, but the panic would not subside. For the rest of the day, I was experiencing sheer terror. I decided to skip the pill that night for fear of the side effects. By the week of Christmas, I was still having panic attacks that last for about 4-6 hours each. The panic was accompanied by a tingling and throbbing sensation in my head. Thankfully, there were parts of the day where I felt nearly like my old self again. Now on December 28, the panic attacks are much more mild and last about 1-2 hours. My fear is that they will never entirely go away. This drug has changed me and I hope and pray that the effects are not permanent. If you went though what I did, there is no WAY y M 40 41 days
40mg 3X W
12/28/2012
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 5  cystic acne. Blackheads. whiteheads Gloopy eyes, dry lips, dry elbows and knees, muscle and joint aches (minor), rib pain (minor), dryer hair (bonus) F 31 9 months
30mg
12/3/2012
 3  To clear mild, but persistent acne Dry, disgusting skin, mood swings, bloody nose, mild hair loss and psoriasis. Not worth the side effects unless acne is severe M 17 4 months
2xD
11/29/2012
 5  Persistent Facial Acne During the course of treatment, I experienced the usual side effects of dry skin, lips, a few nosebleeds, and some temporary headaches. I took Accutane 3 years ago as a last resort (80mg/day). I tried antibiotics, creams, etc. Nothing worked. I had bad facial acne since I was about 16 and it persisted into my early 20s. Three years later, and my face remains clear. I don't have to explain the kind of effects having acne can have on quality of life. It holds you back from so much. This drug has been a miracle to me and my only regret is not taking it earlier. F 24 5 months
80mg 1X day
11/27/2012
 1  Mild Acne Severe hair loss, Severe tight dry crepey skin, recurrance of acne after 12 months, severe depression from physical side effects, muscle wasting in face & upper body, MADE ME UGLY. Premature aging of skin, DO NOT TAKE THIS DRUG!!!!Roaccutane has runied my life. 3 mnths after stopping 10 mnth tx, hair began shedding like crazy and continues 18 mnths later I have about 25% of my hair left ( was long thick and healthy before accutane), my skin has become like a kabuki mask - tight and severley dry and Ive aged about 20 years in 18 months. SUICIDAL does not even begin to describe how depressed I feel. severe dry mouth, yellowing of askin on face, eye brow & lash loss - VERY patchy and not looking like they will grow back either. ROCHE, I hope you all burn n hell for eternity. My life has been robbed from me and I had a great one before this medication F 31 10 months
60mg/40 1X day
9/12/2012
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 5  Acne Aches in my back, hands, feet, knees etc. Extremely dry lips, severe eczema all over my body, severe dandruff (with scabs from having to scrub the flakes twice daily), dry hair. Fantastic results. My skin is beautiful. Prior to accutane, I had such terrible acne on my face, neck, back and chest after two pregnancies. The cysts would never heal or would heal, then return in a couple of weeks. I tried every over the counter product and oral and topical antibiotics to no avail. It was miserable. I have beautiful, glowing skin. Even the blackheads that covered my nose are gone! I would highly recommend this medication. I am very healthy, vegan and exercise regularly. My cholesterol levels actually improved while taking accutane! F 35 10 months
30mg 3X day
6/30/2012
 1  For acne and it worked! Changed my life forever, physically and spirtually. All I gotta say is f* this drug and i hope nobody takes it. M 18 3 years
70 2X day
6/21/2012
 1  Acne It caused anger problems. I got more violent and moody than ever. I never had a mood problem before taking acutane. It has been over a year and that problem has still not worn off. I would rather have felt with the acne than have anger problems for the rest of my life F 17 6 months
30
6/10/2012
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 5  Adult cystic acne Dry lips, dry skin I changed my skin care regime to Cetaphil face wash and cream and noticed very little dryness. My lips remained dry throughout treatment, but I used Aquaphor on them and they were fine. My skin is clear for the first time since having babies and other than minor dryness I had no side effects. Totally worth it! F 33 5 months
40 1X day
6/6/2012
 1  
1X day
6/3/2012
 5  To help with acne I read a woman who said the depression side is a load of crap and I want to say to her that she's full of crap actually, I am a terrifically upbeat person in living relationship with happy job and can tell you this drug mixes up your emotions in waves. I would say that if you are a sensitive character your natural worries and feelings will be enhanced and you will pass from waves of feeling worthless to feeling angry. Despite this and the incredibly sore dry lips this is the absolute cure for acne. My sister took it ten years ago and has not needed another course so far. I am into my second month and my deep dark blackheads and pores have almost disappeared entirely something I never thought possible. Thank god my nightmare is finally over. F 29 2 months
30mg
5/12/2012
 5  Only option that worked Extreme fatigue, very chapped lips, nose bleeds, dandriff,eczema, conjunctivitis, overall dry skin, hair loss (eyebrows and eyelashes specifically). I also had some changes in vision, as well as sensitivity to sun. One of the worst side effects was that the corners of my mouth got really dry to the point where I couldn't eat without causing it to bleed. Depression was another thing, but I was also dealing with many outside factors that could have played a part in getting the depression, but I think that the accutane had some effect on it as well. However, most of the side effects were treatable and I have been able to cope with them and I think that it will be worth it to have clear skin. I have been told that my skin had cleared up, but for right now the psychological side effects of the drug have kind of made me feel like there wasn't much of a change, but as soon as the side effects wear off, I will probably be greatful that I decided to go on accutane. F 17 4 months
40 MG
5/10/2012
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