PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Acid Stomach pain that makes me feel hungry all the time and at the same time I feel like throwing up, asthma (I hear wheezing every morning since I started taking it), achy feeling all over, bloated, constipation, stomach gurgling, brain fog. I feel worse than I did before. I think I'll just watch what I eat and look for a natural alternative to deal with stomach acid. I am glad that I only took it for 5 days after reading everyone's comments. F 34 5 days
20.6 MG 1X day
1/19/2011
 2  Possible ulcer. Rec. by doctor Since I've been taking the Prilosec OTC, I have had very bad chest pains. It feels like i'm having a heart attack and it's really hard to breathe! M 24 5 days
2/19/2008
 2  acid reflux After the day three of the recommended fourteen day course I developed severe stomach, lower abdomen pain which was constant, nausea and bloating. I thought I had food poisioning. I continued taking prilosec with symptoms worsening, so I discontinued use. Going on my third day without prilosec and the symtoms are slowly going away. I read the enclosed documentation and followed the dosing directions. This is the first medication where I experienced any side affects. I was not taking any other meds while taking prilosec. M 57 5 days
1/22/2009
 2  Heart Burn Palpitations, upset stomach/nausea, chest pain, chest tightness, a bit short of breath, fatigue I thought I was crazy, like a lot of other people on this medication. I'd only been on it for 3 days before I felt the symptoms. I was sitting, eating breakfast and right as it kicked in I suddenly felt my chest was tight, harder to breath. It didn't go away the entire day which was unusual, not like the mild chest ache from heart burn. I was scared of course! I thought I was having a heart attack or something was just really really off. A lot of other people say this medication spiked their anxiety; I'm not sure if the omeprazole gave me anxiety or just the symptoms made me more panicky. The frustrating thing is the more I worried, the more the possibility that I was making it worse. I was so relieved to find other people commenting on this medication, I teared up. So even people only on it for a short time also feel like death is behind them! I didn't want to eat, I could barely do basic things I was so tired, and of course I was scared out of my mind that I was dying. It's only been one day I'm off of it, and the palpitations started up. I wish I didn't have to think about them, that's why I'm writing this to give help to someone who may need it. I think that if you've found other medications to make you sleepy or give you brain-fog, or basically mess with your head, this one may too. Besides that PPI drugs don't even fix heartburn necessarily, they just block the acid but the moment you're off the medication, the floodgates open and in come all the acid. F 18 5 days
20 mg 1X day
7/17/2018
 1  Reflux Extreme anxiety/panic attacks, sweaty palms and feet to the point my skin peeled, body twitches, pins and needles, chest pain, lightheaded, lost 10 lbs in 1 week, icy hot sensation on skin, and tons more Worst time of my life. I thought I was dying or going crazy. the anxiety was unbearable. I spent 1k on dr visits and testing only to do my research and find out it was the Prilosec. Been off for about 6 weeks and finally feel 98% back to normal. The physical symptoms stopped about 2-3 weeks after stopping. Horrible rebound reflux started about 2 weeks after stopping and lasted about 1.5 weeks (pure torture) the anxiety is lingering a little bit, but I'm able to leave the house again and drive without having an attack. F 29 5 days
20mg 1xD
12/23/2016
Email
 1  Acid/indigestion post virus Whilst on meds - Intense anxiety Inability to sit still Body jolts Shaking Jilting awake, even though I was so tired Coming off meds Tearful Low mood Burning sensations Pains in muscles (Legs) Pins and needles in head/arms and legs Brain fog I've been off these meds four weeks and still having issues with brain fog, headaches, burning feeling (mostly in upper back), Low mood Pins & needles Although I was recovering from a virus when I started taking this, I was calm and of a positive disposition before. Please can anyone tell me how long they experienced symptoms after coming off this awful drug! F 39 5 days
20mg
6/10/2020
Email
 1  Reflux/post viral indigestion Whilst on meds - Intense Anxiety, racing thoughts, panic attacks, jittering, jolting awake, shaking muscles, pain in neck, headaches, general ill feeling. UPDATE - Been off drug seven weeks. Have noticed some improvements, but still suffering. I have noticed that if I don't eat regularly I feel awful. Also around an hour after eating my body starts throbbing, like it's pulsating all over, has anyone else had this? I'm also feeling nauseous, which is new and the headaches are bad!! Some says I feel so on edge again, which had passed. Please can people who have recovered message, or if you want to chat. 39 5 days
20mg
7/2/2020
Email
 1  Chronic nausea and vomiting Increased nausea, upset stomach, foggy head, headaches, anxiety, depression, appetite loss, heart palpitations, chest spasms, eye sensitivity, grogginess I started a 12 day treatment of Prilosec OTC as prescribed by my G.I. for chronic nausea and vomiting in the mornings. I didn't notice any positive changes and by the second day my stomach was feeling worse that usual. By the fourth day I was in a fog and couldn't focus even though I take Adderall for A.D.D. I noticed that driving felt strange because my sense of time was off. Driving places seemed quicker than usual and almost unreal, sometimes even forgetting if I had stopped at the stop sign I just passed. By the fifth day I felt on the verge of puking and had the worst debilitating headache. After looking up "Prilosec headaches" I found this page and saw that everyone had the same negative side effects that I was experiencing. I'm grateful I did too, because I would've suffered through the rest of the 12 day treatment if I continued using Prilosec. F 21 5 days
20 MG 1X day
9/10/2020
 1  Acid Reflux. GERD Nausea - all the time. Chest pains, feeling dizzy, bloating, no appetite. Increased sweating. Tingling in fingers, lips. Sometimes pain in leg. I feel so ill all the time. The nausea is the worst thing. I don't want to look at food or prepare it let alone eat it. And yet I feel full and bloated. Also have tingling in arms and dull pain in left arm from time to time. Dull chest pain (I even went to get heart checked but it was OK). I tried to come off the medication slowly and finished on 28th January. How much longer will I have to feel ill? I would be grateful if anyone wants to email tips, how they are coping with the symptoms. How long did they go on for? Thanks F 64 5 days
20mg 2X day
2/17/2021
Email
 1  Acid reflux F 45 5 days
20 mg 1X day
2/18/2021
 1  GERD/ heartburn Thought I was losing my mind. The most dark and deep soul-less, hopeless, despair filled week in my entire life. Crying uncontrollably various times each day. Considered multiple ER visits. Called hotlines because I thought I was losing it. Fearful of everything. Detached from my loved ones. Completely, utterly debilitating and horrifying side effects. Not to mention the most awful migraines, nausea, chest pain, stomach issues, body aches, etc. Eventually did some searching and found these posts and other sites. I stopped the drug immediately. It has been two days since I stopped. Still having panic/ anxiety attacks but not as long lasting, frequent or severe. Still having stomach issues and chest pain, body aches. Can finally eat somewhat normally again. DO. NOT. EVER. TAKE. F 37 5 days
20 mg 1X day
4/28/2021
 1  Silent reflux High and severe anxiety, irrational fear, loss of appetite, nausea, shaking and jitters, throat tightness or lump in throat feeling, chest pains, severe panic attacks, racing heart, awaking from sleep with racing heart and anxiety, insomnia, hot flashes, cold shakes and sweats, lightheaded, feeling of doom or hopelessness, mood swings and extreme sadness. F 26 5 days
1X day
1/24/2022
Email
 1  Esophagitis Do not, I repeat do not take this medication if you have no prior history of headaches. I never had them before I took this, and since I've developed SUNCT syndrome along with other problems. M 22 5 days
10/20/2014
 1  Reflux due to high/low acid(???) Dry mouth, trembling, leg muscle twitching, shortness of breath, labored breathing, confusion, anxiety. After being on this medication for five days with no side effects other than headaches, I had to call my Gastro Dr. at 9:00pm last night. I almost went to ER, but the symptoms of overdose/allergic reaction subsided by 10:30. Dr. recommended discontinue medication and seek emergency treatment if symptoms did not subside in an hour or so. I had an endoscopy last week, but no issues came up. I asked about acid presence during endoscopy, but Dr. said there was none present -I had fasted for 16 hours though. He said I still may have too high acid, but I also may have too low acid (either could cause reflux, I suspect low acid). This has not been confirmed by my Dr, either way. I tried a baking soda test at home this morning for low acid, and it seems to lean that way (going to retest this), and going to try Betaine HCL as another at-home test. M 48 5 days
20 MG 2X day
3/15/2015
Email
 1  Ulceration in stomach This drug is terrible. It interacts with my Klonopin, causes stomach pain and nausea, nervous system issues like vertigo, low blood pressure caused by dehydration (that I cannot seem to fix, even after 1 gallon of water +), and diarrhea. F 25 5 days
20 mg
7/24/2015
Email
 1  stomach pain Gave me anxiety and I could not sleep. Neurologist said it should never have been prescribed to me as it causes anxiety and seizures. I already have both. DON'T TAKE THIS POISON M 13 5 days
30 1X day
11/8/2015
 1  GERD Headache all the time, dizziness, finally on day 5 blurred vision in left eye, severe enough to have to see a doctor, no GI side effects, but felt very jittery and easily startled, weird feelings. No reason to take this drug. Gaviscon works far better and has minimal side effects! F 62 5 days
1/20/2009
 1  Acid reflux, Bloating, pain in back On the fourth day i noticed my face getting numb, followed by my hands, forearms, legs then torso. Then at night i couldnt sleep, i couldnt lay in same spot for more than 10 mins without getting dizzy and havint to turn over. Following morning i could hardly move as had severe muscle weakness and was very very tired. Lastly was the palpitations that came on two-three times a day. I had used Prilosec (omeprazole) before around 4 years ago and had the numbness and palpitations then. At the time i didnt link this to the drug. I phoned the doctor who told me that he didnt think it was the drug that was causing this but to stop anyway. I have stopped and 2 days later i still have some symptoms. Muscles feel about 70% back to normal and there is still a small amount of numbness in my hands and face. I also have sore neck and shoulders and am still quite tired. The doctor says that i am 'anxious' well who wouldnt be... i thought i had something incurable!! I dont know how long this stuff stays in your system and wouldnt wish the effects on anyone (although it would help if the doctors could feel what you felt instead of labeling you as 'anxious' or a 'hypochondriac' It would be great to hear from anyone that has or have had the same symptoms as i would love to know how quickly symptoms are going away. M 34 5 days
12/12/2008
Email
 1  GERD general "out of it feeling", anxiety went through the roof, felt like I was having a heart attack even at my age and level of good health, shoulder/neck pain. Hot flashes, throat feels like something is lodged in it. Lack of Concentration. I have bad heartburn due to drinking too many diet cokes over my College career. Started taking prilosec to try and fix it. Side effects are much worse than actual heartburn. You have a constant "down in the dumps" feeling which comes and goes. I have always been a very anxious happy-go-lucky type of guy, after taking this it has slowly turned me into a very anxious, jumpy, nerve-wrecked man. I am stopping taking it TODAY M 23 5 days
2/8/2008
 1  heartburn Dizzyness, headache, testicular pain, stomach pain, constipation I took it for 5 days and decided to quit. Feeling much better after 3 days drug free. I will avoid all drugs in future unless essential. M 53 5 days
6/10/2009

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