PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  possible ulcer Bloating, weight gain, fatigue, anxiety (jittery like), gurgling sounds in left quadrant of abdomen. Would not take it again, I gained 6 pounds in 5 months and I am only 5 feet tall - so it was a lot of weight gain for me. Two weeks after I went cold turkey, I had lost 5 lbs. Also do not go off it cold turkey or you will have an acid reflux problem that is intense. Wean yourself and wean your acid (coffee etc). Then find a nother medicine. I am taking up bike riding and hot baths. Get an endoscopy to get properly diagnosed. F 48 5 months
10/31/2008
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 1  GERD Muscle aches and weakness especially in the upper arms (Biceps and Triceps), back and thighs, dizziness, palpitations. I am a physician, and have recommended this medication to patients for years. And often due to financial reasons, I would prescribe 2 pills daily as opposed to the single in order to achieve the "Prescribed Rx. dose". When my own gerd/reflux got out of control, I took this medication myself. Did wonders for my symptoms which completely resolved. But the previously mentioned side effects I described caused me to go searching for answers. I will no longer prescribe for my patients or for myself. M 38 5 months
12/2/2008
 1  Acid reflux First month taking it I started feeling good on my stomach. Second month I started feeling anxiety and chest pain. Later came rapid heart beats and panic attacks. Numbness on my right hand, arm and feet, also I would wake up in the middle of night because I couldn't breathe. At last shortness of breathe during the day. So I took 2 Covid tests thinking I had Covid on the second and third month and both came out Negative. I stopped taking Prilosec also know as Omeprazole. I change the way I eat and now I'm taking natural remedies and little by little I started to feel better. If your doctor prescribed you this medication you should take it helps at first and each body is different but if you get this bad side effects talk to your doctor about it could be the medication or you have something else. But personally I don't recommend this medication I thought I was going crazy will all chest pain and weird feelings. M 26 5 months
20mg 1X day
8/16/2020
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 1  Gastroenteritis I really regret taking prilosec, i fell ill with a virus last december that caused gastroenteritis (severe acid reflux and diarrhea).. i was told to take omeprazole for 14 day treatment.. at the time i did not experience any side effects so after the 14 day treatment was over, about a week later i experienced acid rebound that sent me to the ER. The er dr said i needed to up the dose to 40 mg 2x/day... and this is when i became more ill.. i had severe diarrhea for 9 days, blurry vision, brain fog, muscle twitching, cramping, body jolts before going to sleep, . i couldnt digest my food.. but i did not know what was happening to me.. i was so sick i had to have a colonoscopy and egd.. i was told i had unspecified colitis.. i stupidly cont this drug bc thats what the drs told me to do.. and as im trying to heal my gut from whatever virus i had i started to develop new symptoms.. extreme brain fog, memory loss, fatigue, anxiety, muscle twitching, buzzing in certain parts of my body.. frequent urination in am. I feel as if i have nerve damage of some kind because of this ppi.. after 4 1/2 months of this posion i have since stopped this med and it has been 11 days but my twitching is still there.. i know this drug caused these other problems bc as i weaned from 40 mg to 20mg to then every other day i began experiencing body jolts and more nerve problems, numbness in certain parts, etc. has this happened to anyone else and did anyone make a full recovery?? I need some help please.. Awful, do not take this drug. F 33 5 months
40mg
6/21/2018
 1  LPR, stomach bleed from endoscopy Brain fog, irritability, easily stressed, depression, increased anxiety, muscle aches, numb limbs, heart palpitations, join paint especially in right shoulder and arm, wrist pain, memory and attention issues.. probably more. ***update*** This drug treats the symptoms of acid reflux. This should not be used long term. Find out the underlying cause of your issues! If you must take it long term make sure you're in the care of a good doc that will test your vitamin levels regularly.. B12, iron, magnesium, D etc. This drug will likely cause more harm than good even if it isn't immediately. I am still suffering with minor improvements after 4 weeks off the drug. M 27 5 months
40mg 1x da
12/12/2018
 1  Gerd Brain fog, extreme anxiety, right chest, shoulder, back and under arm pain.. can't tell if it's from tension or just pain, hard to describe, bloating, indigestion, weight gain, magnesium deficiency I quit Prilosec the first time without having any natural tools to combat the rebound (which my doctor did not warn me about when his prescription ended) had severe reflux and esophageal spasms. This drug is a nightmare, cure GERD by increasing stomach acid not lowering it. This drug makes things worse for your gut and leaves you malnourished! M 27 5 months
40mg 1x
11/14/2018
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 1  Gerds Update from 12-8-19 I have stopped prilosec twice since then but had to go back on it because of nasty bad rebound effects. Stopped again June 1st. Again bad rebound effects. Headache, dizziness, chest pain, heavy head with pain, bad backache, crying spells, leg pain both legs, trouble sleeping, acid in throat, cough, stomach ache, and gas. I am really trying to stay off this poison. Don't take it. Went to the ER and was told to get off it or it will only get worse. Taking tums, chamomile tea, eating nothing after 3:00 p.m. Head propped up to get some sleep. Please don't take this poison. I fear for my health and you should to. So dizzy even laying down. ER says 2-4 weeks and the dizziness should go away they are wrong. All test come back normal. They say my age 64 it may take another two weeks. Poison !!!! F 64 5 months
20mg. Dail
6/29/2020
 5  Extreme heartburn in the evening A dry cough, mostly at night. I have very little side effects and have been taking OTC Prilosec for about 6 months. The benefits outweigh any side effects I experience. F 56 6 months
8/6/2007
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 5  GERD and acid reflux It seems that I've lost a lot of the sensation of impending bowel movements until the very last minute, and then I have to run for the bathroom. Not diarrhea but just urgency. I've never had this problem before, and have had several close calls. Prilosec OTC totally controls my acid reflux and GERD symptoms. I've been taking it six months, and my doctor said I should be able to take it for the rest of my life. However, the side effect of decreased bowel control outweighs the benefits (as great as they are), so I have discontinued its use. After one week, the side effects are clearing up, but the acid reflux pain is back with a vengeance. If Prilosec OTC came in a 1/2 strength, that would probably control my acid reflux with less problem "down below", but I don't think it does, and you're advised not to cut the pills in half. What's a girl to do? F 55 6 months
8/27/2005
 5  acid reflux slight headache at first, then none at all I suffered from acid reflux for 15 years or more and tried everything you can imagine, nothing worked- Prilosec has worked curing my acid reflux symptoms 100%! It really has changed my life. M 35 6 months
4/28/2001
 4  Gerd Muscle weakness, joint pain. Prilosec has been great for my Gerd. Dr. said after 5 months to go off it and see how I did. Then started to experience severe rebound joint and muscle pain. I thought I had the flu. I wish he had informed me there could be a rebound effect. I didn't want to go back on as I learned prilosec can contribute to osteoarthritis and became concerned, but my Gerd came back immediately. I was so uncomfortable I felt I needed to go back on it. Then I read that you can get a prescription for 10 mg and I wanted to try it at a lower dose. Unbelievable huh? The over the counter medicine is 20 mg, but you need a prescription for the 10 mg. I asked my dr to presribe this as we all know "one size doesn't fit all." I have been on 10mg for just 2 days and my Gerd has not been back. Maybe others should ask their dr to go on a lower dose? I hope to eventually go on it once every other day, watch my diet, and hope I can eventually discontinue it all together. F 52 6 months
20 1X day
9/6/2010
 4  GERD OMG.......Hot Flashes, Night Sweats......More Hot Flashes than I can even begin to describe. I "thought" since I just turned 50 that this was my "menopause". They are worse at night after I eat and horrible when I go to bed. Now they are beginning to happen during the day. Last night when I was having an "attack" as I call them, I looked up what else could cause hot flashes and woila.....there it was PRILOSEC. Just put a call into my doctor to get myself off the stuff. Thank God for the internet! Oh, I also have dry skin and I've put on about 40 lbs. Guess what else is linked to these? Yep, PRILOSEC.........I'm not a fan F 50 6 months
10 mg 1X day
3/15/2012
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 4  acid reflux Works wonderfully, feel great. Initially, had accelerated bowel function. But....makes me eat and gain weight. I can't explain the compulsive eating I experience after about 3 days of this medicine. As soon as I switch back to pepcid, my appetite disappears, but I crave the relief that I experience with Prilosec. F 55 6 months
7/17/2006
Email
 3  stomach ulcer F 25 6 months
5/31/2006
 3  Acid Reflux Dr. tried Nexium but my tongue swelled and burned, apparently it happens in 1 % of people. He put me on Prilosec otc 20 mgs, didn't help so he put me on 20 mgs twice a day. I still have reflux especially if i bend over or slip and eat anything with fat. I drink tons of water, don't smoke or drink alcohol. I have been researching natural methods. Read a tsp spoon of honey may help, before meals and a tablet called DGL it is derived form licorice. Didn't like reading that it may cause depression since I have felt a little depreesed lately, never thought of the Prilosec. My insurance does cover it if the Dr. writes a script for it, but wow reading all these side effects sure has scared me, but my attacks were so bad made him give me an E.K.G and a stress test, which were fine. Even had an edoscope to see if there was anything else going on, but no. Love to garden how am I not going to bend over? Have gained a few lbs come to think of it. Definetly going to keep researching some natural ways. Anyone have any luck with the natural route? F 61 6 months
4/14/2006
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 3  acid reflux shaking, numbness in arms and legs, heart palpitations, increased anxiety, constant fatigue My doctor put me on this drug to control my constant acid reflux. I have been on it for maybe six months or more and have just started to have these symptoms. I have been to the ER four times in the last six days with the same symptoms and all the usual tests have come back normal. After reading others complaints, I can only deduce that my long time on this drug has caused these effects. F 31 6 months
20 - 40 mg 1X day
6/18/2011
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 3  Oesophagitis / Acid Reflux Initially this worked really well & immediately was able to resume eating again. Had trouble swallowing for a year prior. Healed Oesophagitis. Then I realized I was ADDICTED. Began needing more & more to control reflux. DR. suggested I stay on it permanently. It took 3-4 miserable weeks to get off this stuff. Used Maalox pills & liquid, Rolaids, Gas X, & Activated Charcoal (Charcoal can be found at health food store) Gained 15lbs. in 6 months. This was a first. Still having stomach pain, bloating, gas, generally feel miserable. Still using Activated CHARCOAL, Gas x & Maalox. Symptoms are less some days. Who knows how long this will last. Feels like some Bacteria is overgrown in GI tract. DR. did not explain that PPI taken long term can allow Bacteria to overgrow until after I was on it for 5+ months. Thanks Doc. DR. decided that my GI tract may have suddenly become hyper-sensitive. So they wanted me to take NOR-tryptaline. Another med. with lots of bad side effects. I doubt my stomach has suddenly become sensitive. NO THANKS DOC. I'LL KEEP WORKING ON IT MYSELF. ACTIVATED CHARCOAL IS HELPING. NOW I GOT TO TRY TO LOSE THIS WEIGHT. M 46 6 months
20mg 2X day
2/9/2011
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 3  Severe Daily Heartburn Prilosec totally eliminated the heartburn. However, I began to experience significant joint pain (elbow/wrist) and later in the knees and lower back to a lesser extent. Finally realized it might be due to the Prilosec. Stopped taking it and 3 days later the pain is virtually gone. I'm now trying Zantac. M 49 6 months
20 mg 1X day
6/23/2010
 3  Gastric erosion Numbness, tingling, twitching This is an update to my comment from 7/9/2020. I saw a neurologist who did many scans, blood tests, and nerve tests trying to figure out the source of my numbness and tingling, but everything has come back normal. He can't find the source, but said it doesn't seem to be a serious health problem, so that's good. About a month ago I was put on a different PPI (Protonix) and my numbness is still present, but it is getting a little better. I guess I'll never know if Prilosec had anything to do with it, but it is interesting that so many people here have experienced similar issues. I developed these issues after taking it, so I will always wonder. This was not a fun chapter in my life but things seem to be improving. If you are experiencing weird symptoms, you should see a doctor and not just assume Prilosec is your problem (althought it might be!). M 35 6 months
40 1X day
8/12/2020
 3  Acid Reflux I had acid reflux really bad when I was 22 and tried this. It worked. It took a very long time to actually work though. It took about 6 months to make me feel 100% better. I'm now 30 and haven't taken it in a long time, but now have severe acid reflux (keep in mind I did not take this for the last 7 years so it's mainly from poor eating habits). I have taken it for a month so far with no improvements. I am hoping it will kick in eventually. This isn't the type of drug to work right away, you really need to think long term with it, and also change your eating habits in order to feel better. It my experiences it got worse for a while before it got better. For a whole month mine felt worse, but now I feel like it's starting to let up. If it doesn't work even a little bit after 2 months I suggest taking something else. Some meds make it worse to the point it's unbearable and losec shouldn't do that. It might make it worse a little and it's uncomfortable since your stomach isn't used to it Works but takes a while. F 30 6 months
40mg 1X day
7/3/2016
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