PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Occasional Heartburn Lethargy, rash and itching on entire bodyaches, flu-like symptoms, ear problems, no appetite, constipation.... so many things. People thought I was hypochondriac! Please, Do NOT take this and when stopping, do NOT give up! This has been an on and off 6 month struggle... I have been off them now for almost 2 months. There is a rebound effect but try to get by! I didn't even get to have a cookie on my birthday and am praying I can eat Christmas dinner and not feel so weak. Please... I keep telling myself it will go away and praying every single day, trying to get more vitamins in my system through boost drinks. I was on these meds for total of 3 months or so (adding all time together) and I pray to be better soon! I have to put off wedding plans because of this!!! Don't give up.... I have a friend who went through this too.. it does get better. Don't give in and go on more medicine! PLEASE! EMAIL ME IF YOU WANT SUPPORT!! F 24 3 months
12/15/2008
 1  acid reflux vertigo, tingling in arms, feet, hands, face, dizziness, vibration (felt like a cell phone) in right foot, leg tremors, facial tremors/spasms, extreme anxiety (can't say this wasn't my reaction to other symptoms), extreme joint pain, especially in ankles, feeling of weight on chest, siderweb-like visual distortion/hallucination at one point. Thinking back, I realize the tingling began almost immediately upon beginning Prilosec. The other side effects began to set in after 1 month. Well I should have believed everyone else on this website. I ended up getting a $9000 plus MRI to rule out MS which my neurologist thought I had. 3 doctors told me it could not be the Prilosec! I went off Prilosec 3 weeks ago--joint pain went away quickly, everything but tingling has tapered off. Tingling is much reduced though. Just got my MRI results yesterday...Thank God! Alas, my acid reflux has now returned. But I'll find some other way to handle it. F 41 3 months
5/28/2009
 1  acid reflux I began to feel tired. Later my joints & bones began to hurt. Heated sensations in my legs like a hot rag was pressing on me.The worst of all was the numbness and painful tingling in my hands, feet & shoulders. I now know that this drug took my B-12 out of my nervous system. It has been very scary these painful sensations I still have even after being off this drug for 3 months.I regret ever doing this to myself. I never had anything like this before I took Prilosec.I am taking B-12 Now and hope & pray that I can reverse the damage.I still have the bad side effects, including the headaches. I never had before. I just had acid reflux & wish that I had not taken my doctors advice & ever took this drug. AVOID THIS DRUG FOLKS. F 53 3 months
11/30/2008
 1  reflux insomnia after taking for a while, anemia, helped with the reflux though turns out I have too little acid instead of having too much (normal aging thing), same symptoms, test by seeing if a spoonful of white vinegar helps or makes worse, need more acid to absorb nutrients F 53 3 months
3/15/2008
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 1   SEVERE:anxiety, depression,panic attacks. Thought I was going crazy, losing touch with reality, nausea, vomiting,had to drop out of college because I literally couldn't/can't function. When taking Prilosec I was fine, it was when I stopped taking it (which the doctor said I could) that these symptoms started to happen.This drug is poison, DO NOT TAKE IT.It has been three weeks since I stopped taking it and I am still not back to normal. When I went to the doctor, he said it had nothing to do with the prilosec and that I needed to go on antidepressants-this is untrue, I have never had mental health problems in the past and they came on very suddenly as soon as I stopped taking Prilosec.DO NOT TAKE THIS DRUG, it is ruining my life. I would like to hear about how long after they stopped taking the drug, you felt normal again, because I can hardly take this. F 18 3 months
2X day
4/5/2011
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 1  acid reflux palpitations, anxiety, depression, derealization, heart palpitations, joint pain, insomnia, massive weight loss, fatigue. Took it for 3 months, had alot of symptoms and didn't know the reason, when a dr told me to take it twice a day everything became worse and I stopped cold turkey. I have been off it now for a month, everything is better, still having palpitations and derealization. Turns out I didnt have acid reflux and 3 months of my life went to waste, I lost 25 pounds in the 1st month. Anyone know how long till the symptoms go away? plz contact me if you do. M 21 3 months
20.6 1X day
5/12/2011
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 1  Gerd I wrote my review 3 days ago just wanted to give a quick update After quitting 3 days ago i have seen some improvement in the side effects but they are not gone all the way. I am still having bouts of palpitations, some anxiety and lump in the throat feeling. I started taking a multivitamin today to see if it helps. I'll give another update soon. M 32 3 months
40 1X day
5/21/2011
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 1  acid reflux/ H-Pylori infection Mind fog, out of body feelings, tingling & cramping in hands, arms. Tense shoulders & neck. High anxiety at times, feels like an adrenaline rush. Also seems to come in waves. I can feel it coming on mid morning. An overall crappy feeling. I took the OTC 2-3 times over the last year. Went in for a routine endoscopy because of family history. Told the Dr. I had been experiencing acid reflux occasionally.Lab reports came back H-Pylori infection in stomach. Was prescribed a NASTY antibiotic regimen,PYLERA, another story alltogether....and told me to double up on Prilosec during that treatment, and that I would be on it pretty much from then on... Started having these"episodes" and feelings soon after the antibiotics, which I know reaked havoc on my body too. In hindsight, I was having smaller episodes over the course of the year,, which i couldn't figure out. All my tests have been normal. Dr. wants me to get MRI , mentioned MS. Recently I was on a trip with some very good friends, and had another episode....basically a panic attack with all those symptoms.My friend told me about her husband's reaction to Prilosec.For him she said his overall personality changed. He stopped taking it, and got back to normal. It never occured to me that it could be this drug. But it's too coincidental to see so many people with the SAME EXACT symptoms as me. Today is day 4 without it. Wondering how long it will take to really feel 'normal' again.& I love how these Dr.s like to hand out prescriptions for Xanax because you come into their office, and start crying like you are out of your mind! It is such a helpless feeling!All they want to do is mask the symptoms, and don't really care about finding the problem. F 41 3 months
20mg-40mg 1X day
6/28/2011
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 1  Produced too much stomach acid Arthritis in my hands and feet (felt like I was walking on marbles), extreme fatigue, lump in my throat, a feeling of being choked, very stiff neck to the point of not being able to turn my head from side to side, sharp pain deep in my left hip (enough to wake me from a deep sleep), hot flashes followed by cold chills After reading the comments on this site, I stopped taking Prilosec. I have been off of it for 7 days. I began to feel better on Day 2. I cannot wait to get this out of my system and return to good health. F 54 3 months
20 MG 1X day
5/12/2012
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 1  gastritis made symptoms worse - a week after discontinuing the drug had five horrible months of colitis like symptoms - the end result was microscopic colitis and B-12 deficiency - suspect I never needed the drug in the first place. F 54 3 months
30 mg 1X day
6/17/2012
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 1  GERD, hiatal hernia, frequent heart burn,indigestion,have been having what I thought was chest pain since I was 12 years old,I thought my heart was hurting and it sharply hurt to breath in,I had to breath shallow little by little until it went away,I was always scared to tell anyone about it,then when I was 27 a doctor finally knew what I was talking about,spitting up stomach acid almost like vomiting,but it just comes up all of the sudden and burning,very nasty, was waking up and couldn't breath until I was able to catch my breath, very scary,thought I was going to die, had endoscopy done almost 9 years ago and a microscopic piece of fatty tissue was cut off my esophagus.I was introduced and prescribed Aciphex,which totally controlled all of my symptoms.I have only been taking Prilosec for 3 1/2 months.My insurance won't pay for Aciphex anymore.Aciphex is the only medication that has ever helped relieve all of my symptoms.I have tried all OTC and other Rx medications such as Nexium and they haven't been able to relieve I feel tired all the time,no energy.My body aches like I have the flu,along with stiff neck and joints.My left rotor cuff in my shoulder is now popping and rubbing.I have had problems with one of my ankles several times thinking I may have twisted it the wrong way,but didn't remember hurting it.I have had severe eye pain in one eye and blurred vision, very scary. The eye pain lasted for days,the blurred vision is now constant and sometimes worse.I wear glasses and contacts and have been drained all the time and have thought my eyes are just tired or my contacts may be defective and my glasses dirty.I've been cleaning them over and over,also thought I may have had a sinus infection,but have never had that happen with one.I have had severe headaches.My periods are longer and heavier.I have had a lot of stomach pain, bloating and gas.I have two little knots on my stomach that are very sore.I'm not sure what they are,they're kind of like cysts.I am really concerned and scared about them.I've been having dizzy almost fainting spells like hyper/hypoglycemia.I sometimes have heart palpatations and sweat and thought it may be early menopause hot flashes and maybe hormone imbalance.Oddly all of these symptoms immediately started after starting Prilosec.I am definately calling my doctor tomorrow.I can't believe I've let this suffering go on this long.It is a relief to probably have found what is causing all of my symptoms.My little boy that is 6 takes Prilosec 10mg.He takes several ot M 36 3 months
20 MG 1X day
6/22/2010
 1  GERD, hiatal hernia, frequent heart He takes several other allergy medications too.He is constantly tired and irritable. He's recently mentioned feeling the "lump" in his throat that I still experience too.I'm thinking it's the Prilosec and will be calling his doctor tomorrow.After reading others experiences and now thinking that's what is causing my symptoms,I definately don't want him taking this stuff.If it's affecting me this way,what is it doing to someone so little?I am thankful I found this site and others have shared their experiences to find help and to help others.I hate it and it is unfortunate others have gone through these terrible experiences. F 36 3 months
20 MG 1X day
6/22/2010
 1  Gastritis Tingling on my arms and legs. Joint pain. Took the med for almost three months and it seemed to help but after the second month I begun experiencing tingling on my arms and legs. I felt tired and not well. Went to the doctor and she decided to do some blood work. They found the I had a severe Vitamin D deficiency for which now I have to take supplements. I am not sure if this med caused the deficiency or if it was due to the gastritis. I stopped the medication after the tingling begun and now the gastritis symptoms have come back. M 46 3 months
20.mg 1X day
6/30/2010
 1  acid reflux and hh depression,chest pain, hair loss F 41 3 months
2/26/2001
 1  acid very bad chest pain. tired weak tingling in hands and legs. lost my job . spent lots of money on mri ekg chest xray . been off it for a week. how long will this last so tired all the time. M 39 3 months
40 2X day
11/27/2010
Email
 1  acid reflux severe anxiety, depression, loss of appetite, suicidal, stinging in the throat, out of my mind and world, very emotional, lack of sleep, dehydrated, metalic tongue, shortnesss of breath and tightness in my chest. This drug about killed me. I was taking the generic brand and thought it was helping. I never put it together what was going on with me until I found this site. I was ready to die. It didn't help my acid reflux, just made it worse. I have been off of the drug for 4 days and still are having some effects. I am not as depressed and the anxiety is starting to go away. Do not take this drug!! BADDDDDD!!!!!!! F 39 3 months
12/11/2009
Email
 1  acid indegestion/ bloating Glad to see I'm not alone or going crazy. Started prilosec in december, for acid. Bloating issues. And the first 14 days were fine but as soon as I was done with 14 days two days later the acid started and the bloating returned. So went back to Dr and he told me again to continue taking it so went to buy more. And symptoms went away. But 2 weeks later my knees, elbows, neck, gums, started aching, my neck felt like static or weird shocks, in my jawline, my joints were achy, was anxious, mild heaches, a lymp node on my neck swolled alittle. Had numbness and tingling in hands for no reason. My throat felt closed sometimes. I couldn't see right at night. Mind you my stomach issues were gone all the other new symptoms were wore neck issues being the worst. I took 3 , 14 day dosages Dr orders. But I have quit taking them have an apt with my Dr next week. I would no recommend this prilosec med. M 29 3 months
20mg 1 day
2/21/2014
Email
 1  Gerd Side effects sneak up on you. I had no idea Prilosec was causing me to feel so bad until I put two and two together. I had been taking this medication for about 3 months. It did help with acid reflux and gerd. I began to have daily headaches. My jaw began to ache and I thought I was having problems with TMJ syndrome. I also started to have constipation and a weird full feeling while my stomach was growling. Most troubling for me was the terrible panic attacks, severe depression and racing thoughts. I was ready to check myself in at a psych ward. I also experienced weird body aches and pains and feelings of complete exhaustion. I really thought I had a terminal disease or the end was near for me. I asked the Doctor if Prilosec could be causing all this but was told "no, it's a great drug". Yeah, right! PLEASE, PLEASE, PLEASE do yourself a favor and do not take this drug. It will sneak up on you and will change for life in a bad way. I have now been off of it for 4 days and I am starting to feel better already. Bad side effects are beginning to go away - thank GOD! M 46 3 months
9/24/2009
 1  Heartburn I experienced extremely swelling and bloatedness in the face. I was on this medication about 6 months ago (along with another med) and noticed the bloating in face. I didn't know if it was from the Prilosec or something else so I went off both. Just started back on Prilosec about 3 days ago and within a day my face became swollen immediately. GOING OFF THIS!!! F 27 3 months
9/24/2009
Email
 1  gastritis, possible ulcer Started having pain in right side up under ribs. Doctor did HIDA scan and ultrasound of gallbladder and was functioning at boarderline normal at 36 (34 is below normal). Found a study from the Univ of North Carolina at Chapel Hill Dr.s Cahan M.A., Balduf L.; Colton K.; Palacioz B.; McCartney W.; Farrell T.M. that showed that Prilosec decreases gallbladder function in healthy people. These people went back to normal after stopping Priolsec. This drug also has a nasty rebound effect for me. I have some bad acid days while trying to wean off. I am currently on a 50% dose (10mg) and want to switch to a 25% dose in 2 days. I am transisitioning to Zantac for a while and then hopefully to nothing. I am taking DGL, L-glutamine and Zinc-Carasate (not sure spelled right). Gastritis appears gone, as is most of the side pain from the gallbladder. Good luck to everyone! God Bless You! F 45 3 months
10/8/2009
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