PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Reflux I was taking OTC prilosec for reflux. I have had the worst symptoms. Joint pain,face numbness and pain, pain in jaw, pain in teeth, head and face pressure. Never take this crap. F 33 2 weeks
20 MG
2/12/2015
 1  Gastritis I switched to this from Protonix due to insurance reasons. I had no symptoms on Protonix. With Prilosec, I have a shaky feeling all over, extreme dry tongue and roof of my mouth, dizziness, heart palpitations, increased anxiety attacks, headaches, fatigue, loss of appetitie and loss of libido. I am so glad I stumbled across this website, I will not be taking another dose of this medicine. I did Nexium over the counter and it worked fine for my gastritis and also didn't give me the major symptoms I am having with Prilosec. F 37 2 weeks
20mg 2X day
1/25/2016
Email
 1  maybe acid reflux, alergy, or asthm headache, mild confusion\dizziness, ear ache, dry mouth, eye pain, numness in right head, muscle cramps and tightness from head to toes, fullness, etc.... drugs.com/prilosec.html Found out from talking to others on the net and the drugs.com website that these 'side effects' are usually caused by over dosage, yes even the 20mg a day dosage for some of us! It should be taken only in the morning with a glass of water. Always wait a full 24 hours before taking the next dosage. Many people choose to way 48 hours, still the 20mg is too strong for some. You should read the entire web site that I show here, it has a list of medications along with mentioning you should not use with vitamins, minerals, etc. They give a phone # to report your side effects to the FDA. Prepare for MASSIVE heart burn after stopping this med. I am on my 3rd day and like others have posted, the heartburn is BAD, and I did not have it before. I've also learned that pillows are inefective, you MUST raise you headboard 6-8" so that the entire bed is tilted. Do not eat or drink anything except water 2 hours before laying down, and 3-4 if it is on the no-no list (milk, fat, carbinated drink (any type), caffine, etc.) Loose weight\excersize. I have also learned that most Americans have Acid Reflux\heartburn at least twice a week. Here's another website that gives REALLY good information. en.wikipedia.org/wiki/Gastroesophageal_reflux_disease M 39 2 weeks
7/13/2009
 1  stomach ulcer losec 20mg MUPS lightheadedness, severe anxiety, feeling out of body experience, feel like I want to scream and run away, feeling depressed, mild headaches, insomnia...the list goes on I am sooooooooooooooo glad to have found this forum. Informed doc that I was feeling these symptoms and could they related be to losec...he said most definitely not!!! The side effects on the enclosed form said that if you experience depression etc. that these have not been proven to be associated with losec...well I beg to differ now. I stopped taking 4 days ago, most side effects have lifted except for I am still experiencing anxiety, blurred vision and feeling shaky....can anyone tell me how long before I am back to normal...as normal can be. I was prescribed losec (and they are expensive paid €63) for possible stomach ulcer (have not officially been diagnosed as have to go for tests)...or could be gallstones (again awaiting tests)...but doc said to keep taking losec anyway....well I'll tell you no more, I feel like shxte. I think some people are more prone to side effects with certain drugs..for example my sister pointed out to me and recalled that when I had the flu once I had an adverse reaction to benylin cold and flu tablets...felt like I was going to faint, head extremely woozy...but nothing like the things I am experiencing with losec. F 39 2 weeks
1/23/2010
Email
 1  acid reflux, GERD anxiety and insomnia. it did help the acid reflux but i traded one negative symptom for two. also, after i stopped taking prilosec the heartburn, acid and nausea returned with a vengeance. this is not a preventative medicine bc your acid will return as soon as you stop taking it. and it might even be worse than before. F 40 2 weeks
20MG 1X day
3/12/2013
Email
 1  GERD, BARROTS. First week was fine. Second week waking up with severe pains in both legs and headaches. This sucks! M 35 2 weeks
40mg
11/19/2013
Email
 1  Supposed Laryngopharyngeal reflux Tightness in neck and chest, pain under chin, severe anxiety... Seriously BAD anxiety. Shortness of breath. I've been trying to figure out what was causing it. Seems like it could be the prilosec OTC, seeing as my chest never hurt from the supposed LPR. I'll never take that garbage again. Been without it for three days. When will the pain and anxiety end? M 26 2 weeks
20mgX1
1/29/2014
Email
 1  acid reflux Took this for GERD. Had squeezing chest pain. Blood pressure increased, anxiety. Took 2 weeks to figure out this was causing problems. Tried generic. Then just quit. Doctor and pharmacist said they never heard of this side effect. But it happened to me. F 54 2 weeks
3/2/2014
 1  Gerd Terrible muscle spasms legs and hips I took this medication for years on and off at 20 mg and always suffered with muscle pain , I didn’t realize that it was the prilosec that gave me those pains until my doctor raised my dosage to 40 mg per day and the muscle pain and spasm got so bad I had to stop taking the medication F 73 2 weeks
40 mg
4/18/2021
 1  mild gastritis Severe back ache. Anxiety. Depression. Hair thinning. Lethargy. Threats of acid reflux even if this is a ppi, acid reducer. Hip pain. Loss of nutrients in the body. I wish I didn't take this from the beginning. Now I am feeling suicida , depression, all kinds of aches in my muscles and joints. Loss of appetite. I wish I've just tried natural supplements. Now I am scared weaning off of this because of rebound/withdrawal. Never ever take this. Never! 37 2 weeks
20 mg
5/20/2016
Email
 1  Chest pain pounding heart, anxiety, inability to breath, dizziness, stiff neck, tight throat, headaches, diarrhea, lost 10 pounds, exhaustion, uncontrollable shaking Both the ER doc and my doctor denied that Prilosec could be the cause and put me on Zoloft and Xanax. I quit the Prilosec but am now afraid to quit the Zoloft until the anxiety calms down. I am feeling better about 6 days out from my last dose of Prilosec. Some things which have helped me so far: lots of carbs and not letting my stomach get empty, magnesium (Calm powder), Minchex tablets as needed for anxiety, valerian root, chamomile tea, green tea, hot baths, exercise (when I have the strength). I’m also taking a quality multi-vitamin, fish oil, priobiotics, and eating fermented foods. Not sure how long these horrible side effects will last but hoping that I improve soon. I can’t work or take care of my child. This stuff should be illegal. F 44 2 weeks
20mg 2X day
3/28/2018
Email
 5  Acid reflux dry mouth, thirsty, usually only on the day I take the pill I was having acid reflux mostly at night, usually only when I had eaten within about 2 hours of going to bed, but did have occasional symptoms during the day. Following suggestions found here and elsewhere, I started with 1 20mg per day, then to one every other day, then tried 1 every 3 days. Taking them in the morning, on the 3rd evening, I experienced mild acid reflux at bedtime, so I switched to taking them in the evening, around suppertime. Now on the 3rd day, I have no reflux at all. M 49 3 weeks
9/13/2005
 5  acid reflux A sudden gain of 4-5 pounds in a couple weeks (without eating more). Loss of usual high energy and drive. Almost daily brief stabbing headaches. It's wonderful to get rid of the acid reflux but I'm anxious to see if I can resolve the reflux and get off meds altogether. For me, this was a sudden onset last month so I'm getting a work-up. F 41 3 weeks
4/10/2006
 5  epigastric pain None My daughter had epigastric pain for 3 months. She was initially put on Zantac that made the symptoms much worse. She was then placed on Prilosec and within 30 minutes began to feel better. Prilosec has been a miracle drug for us! F 10 3 weeks
20 1X day
12/8/2011
Email
 5  gastric damage from NSAID NONE except possible small weight gain which I think is because with the Prilosec I don't get stomach pains. Duh -- eating is pain-free so I believe I eat more and gain weight. Figure it out and maybe it isn' a side effect of the drug but a relief of symptoms which made eating unpleasant. F 78 3 weeks
7/10/2007
 5  acid reflux No side effects that I am aware of. I have only taken Prilosec OTC for about 3 weeks, but so far it has really helped. I was disappointed when I read the comments on this site. I figured most everyone was happy with it. I will pay closer attention to any possible side effects. F 58 3 weeks
12/28/2007
 4  Acid Reflux - I had very bad acid reflux, I would feel bloated, nauseated, burp a lot and get frequent heart burn. My dad told me to try taking prilosec because it helped him out. I tried it for a few weeks and it helped. I didnt feel bloated anymore, I didnt burp as much and didnt feel as nauseated. Before on Prilosec, I woul dhave minor panic attacks which I believe came from the Acid Reflux because I was afraid something would happen in front of everyone. For some stupid reason, I stopped taking it. Well, now it came back. I am picking some up today and will be on it again. I hope it works just as good as last time. M 26 3 weeks
1X day
8/25/2011
Email
 4  Gerd This medicine is not the best, but it has helped me alot. I have alot of joint pain, shoulders really bother me,Sometimes feel alittle foggy headed. I auffer from anxiety already so who is to say this med makes it worse. Overall it helped me, but it didn't cure me at all. The joint pain sucks. I would recomend this med, but not for a long period of time. F 41 3 weeks
20mg 1X day
3/19/2010
 3  Gerd-Lump In Throat Upon third week 40mg a day. Extremely dry throat during sleep, very thirsty all day, worst back pain ever accompanied by super flu-like achyness, muscle cramps, dizzyness and headache with blurryness. My heartburn has subsided but these side effects just hit me hard and I found this page searching for others. It has to be the Prilosec. Will call doctor and explain because I would rather be dead than feel like this. M 32 3 weeks
12/24/2007
 2  Hiatus Hernia/GERD After weeks of stomach problems, had an upper GI and revealed a hiatus hernia. Prescribed Prilosec as Omeprazole 20 mg once a day. Did not agree w/ me at first, but kept on. After a week or so, told myself it WAS helping. Has been over 3 weeks and I am no better at all. Bloating, can hardly eat, reflux, all same as before. It did not make things better and may be making me feel worse. Stopped 2 days ago. Feel the same. Probably something more severe than GERD going on with me. Am not overweight and weigh 109. Developed UTI but doctor said unrelated to medication. Had no mood issues other than the usual. If I have to go back on it I will, or increase dose, but would like to rule out other possibilities, i.e cancer. F 44 3 weeks
5/30/2008

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