PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  gastritis anxious, dizzy, strange feelings in legs, headache would never take this again--very thankful for this website to see comments from others with similar symptoms--stopped taking 24 hours ago, waiting for symptoms to reverse F 66 14 days
20 mg 2X day
7/28/2011
Email
 1  GERD symptoms numbness, tingling and then weakness in left arm and leg (quite scary as it mimic MS) after being on prilosec for 10 days. also got chest pains, heart palpitations. after being on it for 14 days, prilosec did nothing for me except give me these terrible side effects. tried apple cider vinegar with the "mother" with chamomile tea and slippery elm for my gerd symptoms and my symptoms are much better. M 36 14 days
20 1X day
6/20/2011
Email
 1  Acute pancreatitis Severe stomach and back pain. My 11 year old daughter was prescribed this by her pediatrician. Her stomach and back pain went from mild to extremely severe. Two trips to the ER and three extended stays in the hospital before she got to see a GI specialist who deals with adult pancreatitis on a daily basis. Turns out they don't prescribe it to adults with pancreatitis. Within 24 hours of taking it her pain was SO severe and continued until we finally declined it on her 3 rd hospital visit and she started feeling better later that day. I would NEVER take this or give it to anyone I love. F 11 14 days
20 1X day
2/21/2012
Email
 1  Heartburn I had a near fatal allergic reaction to Prilosec around six years ago. My experience may have been atypical: I took Prilosec as recommended (and successfully) for an initial 14 day course. Then, my heartburn gradually came back, but I decided not to do another round of treatment. Instead, I took a prilosec one night when I had run out of rolaids. I became very ill, but did not associate it with the Prilosec. I actually took Prilosec three times more (with increasingly worse reactions each time) before I figured out what was making me sick. The final time I almost died. Ironically, I started having heart arrhythmia simultaneously with the final - worst - reaction. I have no idea of my ongoing arrhythmia has anything to do with the Prilosec but I came very close to dying from this OTC drug. My initial allergic reactions were severe stomach pain, vomiting and diarrhea. It wasn't until the fourth reaction that I had "classic" allergic symptoms - hives, constricted My husband has now (regular Prilosec user) developed persistent Atrial Fibrillation. Related? F 50 14 days
20 mg 1X day
6/2/2012
Email
 1  gerd dry mouth, muscle leg pain, intestinal cramps, gas, lightheaded, back pain, tingling in arms and legs I took prilosec otc for the two weeks recommended on box. Felt all of the side effects. Stopped taking it 6 days ago and still have some of the side effects. How long does it take to feel normal again? I had a prior experience with RX prilosec and had similar side effects. Of course doctors say it is not related. Thought this time would be different. Never again. M 41 14 days
2/4/2009
 1  Stomach problems RAPID Heart Beat- 120-NEVER had before. Stopping immed.-THINK this is causing problem. Pharmasist says not side effect - BULL. We are all not Crazy. Hosp. Dr. after I was admitted put me on this for stomach bleeding. I never had any symptoms, but was vommitting blood one day-went to hosp. Eating better now and off all aspirin used to live on it for headaches. (they failed to bring that up)- Now my heart is racing and hope that stopping this drug today will stop that. How long to get out of system I wonder? F 50 14 days
5/14/2009
 1  GERD and Barrett's Tightness in chest, heart palpations, trouble breathing, nervous feeling, headache, stuffy sinuses, tingling in hands, I felt as though I was on caffine overload I am so happy that I found this website. So many people have listed the same side effects as I was having. I was getting ready to call my PCP and make an appointment to have my heart checked . I have never had heart problems in my life. The palpations got worse when I would lay down at night especially on my left side. I was really starting to get scared. Seemed like nothing I did helped. I also have been taking Protonix 40 mg for several years without any problem. Why he put me on 2 different proton pump inhibitors is beyond me. When I asked I was told that it would help the several digestive problems I have. I haven't taken the Prilosec for 2 days now and I'm starting to feel much better. Thank you everyone that posted their comments about the awful side effects they were having while on this drug. F 62 14 days
5/11/2009
 1  acid reflux I took Prilosec daily for 2 weeks. I experienced unusual coldness in my fingers. They turned yellow with purple nails by afternoon and no amount of hot water on them or hot drinks or hot baths improved the condition. I also felt difficulty in my chest---breathlessness, coughing and pressure---like a weight on my chest. I became extremely thirsty had to get up 3 or 4 times at night. I became constipated. I also experienced muscle and joint pain. I stopped eating after lunch because of the increased feelings and went to bed by 8:00 pm. All my side effects evaporated when I took myself off Prilosec. Of course the acid reflux returned and I need to find an alternative medication for that. F 60 14 days
3/30/2009
 1  GERD severe weakness and fatigue, loss of appetite, depression I was put on this even though my endoscopy showed no problems. Unfortunately, I had a digestive problem and was put on several drugs to help with sypmtoms. I thought my weakness, fatigue, loss of appetite was from my rapid gastric emptying. What I found out was that Prilosec was causing me to be very sick. Within 24 hours of quiting Prilosec I began to feel much better. I have no doubt this medicine is useful to some people. Just be wary. M 48 14 days
12/31/2006
 1  GERD The only fender benders I've ever had, I had while on Prilosec. It's an antihistamine, it makes me stupid; just a little stupid, but it shows. P eliminates stomach acid, therefore makes digesting calcium impossible - if you're post menopausal, this is a disaster; if you're not, your nervous system needs CA, not just bones. I have a GERD cough for a year; the P doesn't help it. I've taken it on and off for years following surgeries with pain killers and antibiotics galore destroying my gut. P. suppresses the immune system. It may suppress acid reflux, the symptom, but the price is very, very high, especially long term. There has to be a better way than H-2 blockers, Mylanta et al. Stop eating? F 68 14 days
11/16/2006
 1  ulcers Accute nausea and severe stabbing pain in lower abdomen unlike anything I have had in 29 years of ulcerative colitus. Intermmitent headaches. Weakness and fatigue. Coughing. F 52 14 days
6/8/2006
 1  Reflux Severe headache and back cramps. Have been on and off the drug multiple times to confirm it wasn't my imagination. The side effects are very definite and predictable. Far worse than the symptoms I was taking the drug for. F 42 14 days
10/11/2006
 4  GERD I tolerated the drug well for 14 days, then, following the instructions I stopped taking it and immediately had much worse acid reflux and nausea than before! So I have started taking the pills again. Why does the drug company limit consumption to 14 days? Are they just covering themselves legally? M 72 15 days
2/15/2009
Email
 3  GERD At first prilosec seemed like a miracle pill. My gerd was gone so quickly and I could sleep at night. By the end of two weeks, appetite increased a great deal. I had awful night time anxiety and difficutly swallowing. This pill worked so well at first, but had to stop by third week. I was dissapointed because I don't want anymore damage to my esophagus. The anxiety that I experienced was very scary, so I stopped taking it. F 53 15 days
8/26/2008
 1  acid reflux metallic taste in mouth, tongue became VERY sore and tingling, "sore throat", gnawing sensation in stomach, bad breath, lumps the size of golfballs that could be palpated mid-neck bilaterally the were very tender, burning in throat/esophagus, exhaustion, joint pain (right iliac crest 5/10, low back/area of kidneys, thumb joints, quad muscle right, left knee), decreased appetite Generic prilosec was prescribed for acid reflux which was causing discomfort and interferring with my ability to sleep. It actually worked beautifully for the acid reflux for the first 3-4 days of taking it. I was so thankful and impressed that I nearly sent my MD flowers! But then the symptoms began as noted under the side effects I listed. Even with stopping it at day 15 (and I am now at day 18) I am still so lethargic and hurting so badly that I can't function very well. The metallic taste and tingling and soreness of my tongue are starting to recede, but my throat and neck still hurt enough that I don't want to eat. I went to see the MD on call at my physicians practice on day 15, they didn't give a definitive answer. I just said I was stopping taking it and they suggested taking Pepcid AC instead, and scheduled me for an upper and lower GI. Haven't done any of those things yet. The side effects have definitely been worse than the reflux. My goal now is to stay away from any medicines as much as possible. Are all doctors really so busy now that they don't have time to care for their patients and discuss the pros and cons of various alternatives? I remember my grandmother used to say, "Doctors bury their mistakes." F 52 15 days
20 mg 2X day
2/6/2010
 1  GERD Joint and muscle pain, loss of appetite, vertigo Diagnosed with a hiatal hernia and put on prilosec. Within days, I had a constant, throbbing ache in my legs and hips, foot cramps, dizziness, and several episodes of vertigo (which I've never had in my life and didn't know what was happening until I looked it up). Awful feeling. After some research, I am going to visit a chiropractor who has successfully "pushed back" hiatal hernias. Seems a common "natural" treatment for my issue, and I'm excited to try it since I will no longer be using prilosec! F 37 16 days
20 mg 1X day
3/23/2011
 1  Acid reflux Anxiety/depression, sadness, feeling of hopelessness about life in general! rapid heart rate, jitters, not at all myself. Stopped taking it four days ago when I realized it was causing these side effects, and I have started slowly getting back to normal each day. My doctor said it could take weeks. I highly recommend NOT taking this drug. F 60 16 days
40 mg 2X day
9/16/2021
 1  GERD Extremely tired, sad, crying, feeling like I was going crazy, very cold I took Prilosec about 10 years ago for GERD and didn't have a problem. However, this time is different. I woke up two days ago with a huge anxiety attack. That has never happened to me. I am normally a pretty calm and carefree person. Ever since then I have these crying spells where I just want to be better. I'm so tired all the time, and even after I take a nap I feel like I could still sleep. I truly feel like I'm going crazy. These side effects are not listed very well (at least not where I have looked). After I found this page, I decided I'm not going crazy and it has to be the Prilosec causing all of these. Today is the first day I have stopped taking it, so hopefully I will improve mentally. F 36 16 days
20 MG 1X day
4/27/2023
Email
 1  Possible GERD, H.Pylori ? Lump in throat, severe throat & mouth burning. Suddenly began having numbness, tingling in hands & fingers plus swelling, increased BP (always low before). Stopped 20 mg. dose following endoscopy & now increase in stomach acidity & discomfort since stopped pill. New gastric distress-increased symptoms. Had endoscopy that was negative.Never advised about side effects. Thought I had some very weird illness or virus. Did not relieve my symptoms now they are worse since stopping dose 5 days ago. Will this end? Any advice as to what to do to control withdrawal. How long does this last? F 63 16 days
12/21/2009
Email
 3  Gastritis Severe migraine, horrible anxiety, constipation, nausea, growling stomach A few years back I took Priolosec and was completely fine on it. I don't remember experiencing any kind of side effect. F 48 17 days
20 mg 2X day
2/16/2014

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