PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Gastritus/ acid reflux muscle pain mostly in legs & hands Stomach pain,bloating,belching.. full feeling all the time severe constipation,,,,Constipated & severe diarreah severe fatigue,tired all the time, felt out of it,,,spacey feeling sinus pain,,, over eyes bad pain over eyes, fel like sinuses were blocked,,,heavy feeling in head blurry vision Annoying eyelid twitch, also twiching all over in differnt muscle areas,intermittant..leg, arm, hand, foot etc. SEVERE (Very Painful).... needle like pinprick pain in toes,fingers, etc. When i got the prescription...i immediately called my pharmacist & asked if there were any adverse reactions to this drug.. i was told "NO"!. Anything i need to be concerned about NO! He said that this was a safe drug. There are NO SIDE EFFECTS with this drug. I dont know how they can say that. I guess i cant even trust my pharmacist...i went online and boom there it was...how can this many people be complaining over & over about side effects? I took the drug out of fear because i didnt want to be hospitalized again for severe gastritus.(the pain was horrible)I am new to this problem but i changed my diet & when i have a acid flare up i take my Maalox advanced and im fine. If i would have known thats all that i needed i would have never touched this drug...i dont understand why a Dr. would prescribe this stuff,,its been 3 weeks since ive stopped this drug and im still having side effects...my left eyelid is still twitching, im having twitching intermittantly in muscles all over. My muscles in my legs are hurting... strangley enough in this past week. Constipation is still there.(taking laxitives)never took them before stomach issues have gotten better. no more bloating etc. Im still waiting for these symptoms to disappear,,,wish i knew how long it takes for it to finally get out of your system. F 41 17 days
6/25/2009
 3  Heartburn, GERD onset? Lightheadedness/dizziness, fatigue/woozieness, sour stomach with bloating/pain. The mental effects are particularly bad 1-3 hours after taking the med, the bloating, etc., starts in the afternoon a few hours after lunch. Seems to work re heartburn/GERD symptoms for a time but has side effects - the bloating and sour stomach started after two weeks on the med. Was using 20 mg once in the AM 1/2 hour before breakfast. Symptoms above disappear when Prilosec discontinued. Have run this A-B several times. M 67 18 days
1/24/2009
 2  GERD Right flank pain, gall bladder pain, belching, acid reflux My gastroenterologist prescribed Prilosec after diagnosing me with GERD (through upper endoscopy). I was surprised at the diagnosis because I had no heartburn. But I did have other GERD symptoms: pain in my ears, coughing after eating, clearing throat, insomnia. After starting the medication I slept a bit better and the pain on the left side of my abdomen was relieved. But I just felt weird. (Can't describe it.) After 18 days I discontinued. And that's when I got actual GERD symptoms: acid reflux, regurgitation, intense heartburn, pain and tightness in chest, palpitations, extreme anxiety. (I'd wake up at midnight feeling like I was going to die.) A couple of times I thought I was having a heart attack and went to the ER. So, my doctor put me back on Prilosec--to relieve the symptoms caused by the Prilosec. The next day I had a full-blown gall bladder attack. Once again, I stopped. I suffered horribly for a week--during which I took every home remedy known to mankind--before the sympto F 54 18 days
11/25/2007
 1  Stomach Acid Shooting head pain, tension headaches, tightness in throat, sinus infection symptoms F 36 18 days
21MG 3X day
4/30/2013
 1  Gastritis Anxiety, increased heart beat, feelings of panic, thoughts seem more obsessive, dry mouth, slow stomach emptying, insomnia, tingling feeling under skin, low mood, some headaches, eye sight seems worse (will be getting this checked out at opticians asap) I was diagnosed with moderate haemorraghic gastritis which was alarming as I don't drink, smoke, take anti inflammatories etc. I have been under stress for some time however. The H Pylori test came back negative but I know this can be wrong. The consultant recommended high dose PPI's however I am intolerant so can just manage this low dose. Even that gives me side effects. I hve to take something for the gastritis and don't know how to manage the increase in anxiety it is causing. Would appreciate any help about dealing with the gastritis without this and also how to deal with / manage the anxiety whilst still on the drug. F 57 18 days
10mg 1X day
12/19/2015
Email
 1  Supposedly Acid Reflux Many side effects, Extreme fatigue, weakness, heart palpitations, anxiety, depression, night sweats, lump in throat, vitamin D deficiency, vitamin B deficiency, Potassium deficiency, back pain, hip pain, lost weight, lost muscle mass, This drug is poison, should be banned. Side effects seem to slowly creep up, day 1 seemed ok, from there on I felt weak and very depressed, by day 12 I was having heart palpitations. I went to ER and they did EKG, blood work, etc and told me I was fine. I had no clue that the Prilosec was causing this so I continued taking it for another 6 days. By then I finally googled it and found this site. That convinced me it was the Prilosec and I stopped taking it that day. The next day the weakness stopped, but the other symptoms lingered. I went to my MD and she ran bloodwork and found the vitamin deficiences, so I started taking the needed supplements and I started feeling better but I still had the heart palpitations and anxiety. So 5 weeks after stopping the prilosec I started taking St. John's Wort and within a week I started feeling much better. St. John's Wort cleans the prilosec out of your bloodstream.... I am very disappointed in FDA and Proctor and Gamble and our drs....... This has been a horrible nightmare that should have never happened. F 55 18 days
20 Mg 1X day
3/21/2014
 1  GERD Extreme weakness in my thigh muscles. Pain in my hip joints that was so extreme it lead me to believe I was going to need a hip replacement in the near future. Weakness in my arms and hands, so much so that using my computer mouse began to become very wearysome. Shortly before I quit taking Prilosec my entire body started to feel like I had the flu, except without the headache. Prilosec is some bad stuff! I would rather have heartburn than feel the way I felt after taking Prilosec! It's back to Provacid for me, although I'm also going to start working out in hopes of loosing weight, which I believe will help. I took Provacid for two years without any problems, until my perscription ran out and I thought I would try Prilosec OTC. What a mistake! Prilosec is a bad joke. I've been off it for over a week and my legs still don't feel back to normal yet. If I know then what I know now, I NEVER would have tried Prilosec! If I could rate Prilosec a zero, (or negative 5), for extremely dissatisfied, I would. M 46 19 days
6/14/2007
 5  daily heartburn none at all I was taking a daily dose of Zantac which moved to two to three doses daily to control the heartburn. Decided to try something new and I'm glad I did. On this site to see if taking it longer than recommended would be a problem and I have found enough positive comments to assure me that I can use this as I did the Zantac. I probably will cut the pills in half but would consider this medicine a rousing success. M 53 20 days
20 1X day
4/1/2010
 4  reflux M 70 20 days
20mg 1X day
2/25/2010
 2  Heartburn anxiety, sleeplessness, occasional muscle twitching legs and arms. very unpleaeant sensations most of the time escpecially at night. Treat was upped from 20 to 40mg per day acid went down all other side effects went up M 44 20 days
12/19/2006
 2  gerd, ibs shakyness, anxiety, lightheadedness, just an overall feeling of uneasyness, weird appetite, bloating, gurgling in stomach, weak and wobbly limbs I was diagnosed with ibs and then i had an endoscopy/sigmoid and the dr. prescribed this drug for me because of an irritated area on my esophogus. he diagnosed me with GERD. At first it seemed ok, I was still having stomach issues which i though was just from the trauma of the procedure. Now ive started paying attention to how im feeling other than my stomach and have developed periodic shakyness(which i assumed was lack of nutrition) and also lightheadedness and weak limbs which i assumed was also the cause of this. Now, these side effects are seeming more prominent and now im wondering if it is actually the meds (generic omeprazole) F 21 20 days
11/27/2008
 1  gastritis tingling arms hands and feet. Leg pain. Sea sick feeling. Headache, pain above eye, Ulnar nerve pain/numbness in pinky and middle finger. Anxiety, pain in chest, insomnia. Joint pain. Pain in ends of fingers. Heart palps. Has anyones doctor told them why we cannot tolerate this stuff? Zantac does the same thing to me and is less effective on stopping my HB. Has anyone found another med that is effective on their HB and reflux without these side effects. Please post if anyone has any advise on what we can do instead of taking this crap. It should be illegal. What really sucks is my doc says it can't be the prilosec or zantac that causes these effects. Does anyone have a good doc out there that admitted it was the prilosec? Good news is side effects do wear off after a few mo's. You have to wean yourself off the prilosec gradually. Take 1/2 a pill and then every other day, etc. Acid rebound is horrible. Please email me if you have found a better med to take or if you know why it affects us this way. Are we allergic? F 41 20 days
3/11/2009
 1  acid reflux, gastritis, hiatal hern Although the medication worked for the most part, I suffered one side effect not mentioned. The reduction in acid caused an increase in clostridia difficile (c diff) that led to diarrhea 4-6 times a day. Now on flagyl (metronizadole) to correct c diff. Switched to Nexium which does not work as well in controlling acid. More info should be available about this common but not talked about side effect. Have to take another stool culture after the flagyl treatment. If positive, doctor suggest vancomycin --which is a *very* strong antibiotic that I wish not to take. M 48 20 days
12/28/2005
Email
 1  GERD Severe fatigue, muscle pain, joint pain, headache, pain at base of skull, cloudiness, confusion, spaciness, heart palpitations. I took this off/on for about a year only when my stomach bothered me. I have recently started taking it again but noticed the severe fatigue right away. I stopped for a few days then took ONE and noticed right away all the above symptoms. The GERD went away but it's not worth it!! Yes, it won't affect everyone this way but with this many people having many of the same side affects, why even risk it? My Dr. never informed me about the malabsorption risks yet prescribed it daily for a year. Scary. M 46 20 days
20 mg 1X day
1/16/2011
Email
 1  heartburn from taking Ibuprofen Anxiety, palpitations, high blood pressure, tingling left arm and possibly left leg. Also belching and constant feeling of gas. I ended up in the ER with an acute high BP, chest pain and an irregular pulse. Settled after 2 days - BP and ECG back to normal. All tests for heart attack normal. M 51 20 days
12/30/2005
Email
 1  Possible stomach ulcer Sore hard patches on hands, diarrhoea, nausea, confusion, vertigo, very painful joints especially wrists and swollen fingers. Feel very unwell to the point I have been unable to do anything for myself. Absolutely no appetite either, I've lost a stone in weight in 3 weeks! I was prescribed these due to a low red blood cell count which my Dr put down to many years of using Diclofenac. I must stress at the point in time I was prescribed them I actually felt very well. Within 5 days I developed sore patches on my palms and ulcers in my mouth, my GP said my hands were a type of eczema and prescribed cream. 5 days later I developed diarrhoea, which my GP said was a bug. I came off the Prilosec for a few days, some of my symptoms improved a little but the tummy didn't. So I stopped the diclofenac and started taking the Prilosec again. I have had such excruciating joint pain, especially in my hands and wrists - I have wrist supports to wear as its so bad. Terrible nausea and diarrhoea, and whole body aching. Very twitchy and unable to settle for long, very low mood and finally yesterday vertigo. I stopped these tablets 2 days ago, yesterday I had the worst day ever and was unable to lift my head off the pillow but today I feel a fair bit brighter. I'm hoping that over the next day or two things will improve so I can return to work. I have also started eating again today after 3 weeks of no appetite and had my first cup of tea that I actually wanted. I have had tests for stomach cancer, pancreatitis, kidney and liver problems etc since taking these. I am also booked for an endoscopy to see what is up. I now believe its the tablets as I had no reflux or gastric problems prior to taking them. F 54 20 days
20mg 1X day
8/18/2013
 1  heart burn/possible acid reflux I posted on 12/08/09 and forgot to list high BP 141/80 normally around 115/70 and ringing in my left ear. I have been off 40mg Omeprazole for 3 weeks now and the side effects have subsided but are still lingering to some degree. My chest pain is gone and my BP is down to 125/70. I still experience some weakness in arms and legs and have strange numbness/tingling sensation in the back of my head and neck.I also find that I am really fatigued at night. No more anxiety or stomach issues. I read that omeprazole can suppress acid production for 3-4 months after you stop taking it. i hope that the side effects don't last that long. M 37 20 days
12/23/2009
Email
 1  heart burn dizziness, light-headed, back, neck and left shoulder pain, weakness in biceps and legs, chest tightness, heart palpitations, abdominal pain, changes in stool, severe anxiety and fatigue I went the the ER one night with severe tightness/ burning in my chest. EKG-Chest X-ray, cardiac enzymes were normal. ER doctor prescribed 40 mg omeprazole and told me to try it for 30 days. After 3 days, I began to experience horrible side effects. I didn't think that prilosec could cause such severe symptoms and thought that I had some condition that was getting. worse. Several blood tests and CT scans later, my doctor could not figure out what was wrong and assured me that prilosec couln't be the cause. Thank God for this website! I stopped taking the omeprazole on Dec 1 and have been getting better ever since. I still and feeling the after effects but not as severe. I hope this stuff gets out of my system soon and that no permanent damage has been done. Please make sure that you ask to try the lowest dosage of prilosec first! 40 mg was overdosing in my case! M 37 20 days
12/8/2009
Email
 1  Acid Reflux Anxiety, Insomnia, Depression, Heart Palpitations, Hot Flashes I found this site in search of comfort. I was looking for some clarity on how long people experienced the side effects. I was supposed to take for 30 days. Only took it for 20 days then started having anxiety and sleeplessness. I didn't link the 2 together I really stopped taking the MED b/c I was on it for throat irritation and felt like it had cleared up so I stopped. It just so happened it was around the same time the sides started. Let me first start by saying I am an excellent sleeper and can normally not even make it through a movie without falling asleep. I can usually take naps no problem and could sleep 10-12 hrs if I didn't have to get up. When I was on vacation all of a sudden I started waking up for no reason(this was about 20 days on the MED) 2-3 times a night. I would wake up feeling hot, and kind of in a panic and felt claustrophobic. I was usually able to get back to sleep. I attributed to not being in my Some things I tried- Drinking Chamomile Tea before bed, melatonin, benydryl, magniesium, b12, b6, multivitamin, CBD oil On about the 2-3 week after stopping the MED I would still wake at night every 1-2 hrs. but would be able to go back asleep within 30 mins or so, I would still feel hot, the anxiety was lower but still intermittent. I was still not anywhere near my normal self but it was more tolerable as I could get some decent sleep and function the next day. Wk 4-6 I cont. to wake less freq. and would be able to get back to sleep within 10 mins. The anxiety was gone mostly After Wk 6 I felt like I was back to normal. I started sleeping through the night, could take nap during day, had no more waking up feeling hot, and no more anxiety. Also I have never had any sleep or anxiety problems ever in my life. I am not sure if any of the vitamins/ meds listed above helped decrease the amount of time to help me get back to myself or not. It could be that your body just needs time. I was willing to do about anything during the 2 worst weeks. I went to a sleep doctor (who just told me I had a sleep maintenance insomnia from anxiety). Anyways it looks like I am back to normal and hopefully no long term effects will be done. But this is a NASTY drug and I will never take again. I hope this helps someone in the future to give you hope that you will get back to normal with time. I had some long and miserable days of wondering if it would ever end. Best Wishes M 37 20 days
40mg 1X day
10/14/2020
 1  Silent reflux Jitters..tingling and numbness in both sides of face neck both arms legs and feet. Muscle spasms all over body. Horrible Brain fog Eye problems, problems with balance walking, chills with no fever, exhausted after doing nothing fatigue all day, weakness in right foot leg and arm. Ms or Parkinson like symptoms. Going to see neurologist soon. After 2 ER visit everything came back normal. After being off it for one week side effects still here Please never take this drug!!!!!!!!! F 35 20 days
40mg once
6/23/2020
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