PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  reflux agitation, panic attacks, crying, out of body feeling..detached...light and sound sensitity...ringing in ears...could not get a deep breath without effort. Psychotic episodes where all I could feel were electrical feeling in my brain,,hands like ice...thought I was dying....I cried everyday. Finally saw a new Kaiser Doctor and she told me she has seen this toxic effect from Prilosec before and that it would take 4-6 weeks to get out of my system and the side effects to go away...I am nearly at that 4 week marker and I am happy to say today I had my first normal day,,got my love of life back, my focus, as I told one man "I got my mojo back!" So hang in there and when you turn a corner let others know. this is one quiet travesty and we suffer in silence because no one understands. So make a big noise and we can help alot of other people. Jane F 56 6 weeks
7/9/2009
Email
 1  Stomach erosion Mainly low back pain, calf tightness and fatigue. No post exercise recovery. Never had back pain before...I am a PT and work this area constantly. Within 1 week was getting never before experienced back pain with the most mild movements. Every joint was tight and my workout recovery was not happening. Off the med today. M 42 6 weeks
10/22/2008
 1  Severe epigastric pain/ vomiting Severe depression, ringing/pressure in ears, anxiety, panic attacks, chest pain/tightness, headaches, extreme fatigue Caused way more problems than cured. Was never informed of side effects. Thought I was going crazy F 30 6 weeks
40 mg 2X day
9/6/2010
Email
 1  acid reflux/heartburn SEVERE: anxiety, depression, hot flashes, night sweats, fatigue coupled with insomnia, heart palpatations, brain fog & confusion, memory problems, blurred vision, dry mouth MODERATE: stomach cramps, nausea, muscle weakness, muscle soreness, muscle twitching, mouth and throat bumps, tingling limbs, complete loss of sex drive, 24 hour "zombie" state of mind i stopped taking this medication 24 hours ago. my symptoms are already improving - much less brain fog, hot flashes are subsiding but have not yet stopped. depression and anxiety already greatly improved. this drug is an AWFUL poison. i honestly believe i was on the verge of becoming suicidal. i truly believed i was going crazy. i will NEVER take this drug again. it was the only medication i was on. i am a very physically active and normally healthy person - eat organic whole foods, work out and run daily. i have no idea what pocessed me to try this drug. there are healthy ways of dealing with acid reflux. clearly i need to do some tweaking to my diet. i believe all the "in-season" fruits and vegies i was consuming may have been a bit too much and will begin cutting back on tomatoes and such. please dont take this poison - you have other options. F 48 6 weeks
20 mg 1X day
8/20/2010
 1  GERD burning throat and mouth, dry mouth with foul taste, sore mouth felt like it had been scalded, bumps in mouth, agitation and severe anxiety. Felt unwell Was never warned about these side effects by doctor and he doubled my dose when I returned to list these symptoms. The info was not on the drug leaflet either. It was only finding this site that alerted me to the problems. I've been off it 2 weeks and only slowly feeling better. 2 days well, 2 days with side effects etc. It seems like a slow process. F 51 6 weeks
40mg 1X day
7/26/2010
 1  Acid Reflux Abdominal cramping, hunger, weight gain, severe pain under ribs on left side. Dr. Prescribed this for acid reflux symptoms. Had test for reflux where they give you the barium drink and lay you down in different positions to see if it comes up your esophagus. They had to practically turn me upside down for them to get their desired result. barium is very heavy so would come up on anyone! Went to homeopathic Dr. She told me about Betaine HCL, which I take with each meal and it really helps with my indigestion symptoms. do your own research into alternative cures for "reflux" symptoms. Eat healthier., digestive acids are reduced as we age, we actually need more acid. I know this sounds strange but it is true in most cases. P.S. a friend of ours just had his stomach removed from having stomach cancer, I know that he was on prilosec for years prior and Nexium too. Not sure they are related to the cancer. F 53 6 weeks
20.6 mg 1X day
9/4/2011
 1  Acid Reflux First I had severe abdominal cramps in my lower stomach in the first 3 days. So i cut my dosage in half to 10mg twice a day. Stomach pain stopped. Then I gained 15 lbs over the next 6 weeks. I also started having chest tightness and chest pain. I started to wonder what was going on so I googled Prilosec and side effects. This is a bad drug. I have had abdominal pain, left side chest pain and tightness on the left side, shortness of breath, when I eat it feels like the food stays there in my stomach for days, face and muscle twitches, severe weight gain, and an uneasy feeling like anxiety. I would not take this drug. M 50 6 weeks
20mg 2X day
3/3/2012
Email
 1  Reflux, small area of Barrett's You name it, I had it! Anxiety, tinnitus, nausea, dizziness, loss of appetite, chills, lump in throat. Dr. changed ppi 3 different times. Have been in ER every week since starting these meds due to the side effects. Tons of tests done that were all negative. I have never been this sick ever!!!! Decided to go off cold turkey and on day 4 without med. Now I know how a drug addict feels. As many have said, this medication is poison and not worth the side effects. Question is, how long will this take? F 51 6 weeks
20 1X day
5/7/2012
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 1  Diagnosed with GERD Brought on GERD symptoms I had not been experiencing: heartburn, sour stomach, and sore throat; I also experienced frequent chills, elevated blood pressure, raw mouth, anxiety, chest pain and palpitations, reduced food intake (all food became problematic), followed by rapid weight loss. This drug may be helpful if experiencing "traditional" GERD symptoms, but I would not recommend it for those who do not. F 48 6 weeks
20 MG 2X day
5/22/2012
Email
 1  Acid reflux Severe stomach cramps deep feeling of doom and gloom sores on the side of mouth and headaches. Prescriped Losac for acid reflux two months ago last couple of weeks noted stomach cramps and abdominal pain getting worse doctor advised stopping Losac for a week and then look at having a colonoscopy if no better. Noted the next day that my tablets were Omeprazol not losec chemist had supplied these about 6 weeks ago which coincided 100% with my symptoms starting. So pleased to have found this web site like all others the excruciating pain and panic attacks were of huge concern. Stopped taking tablets 5 days ago feeling better stomach still playing up but at least 70% better today and feel good in myself again,will have to watch what I eat for the next couple of weeks I think. This is one scary drug. M 58 6 weeks
20 1X day
4/21/2012
Email
 1  Acid reflux The first night taking it, I woke up with severe numbness and tingling in my arms, chest pain, stomach tenderness, and my husband said I looked very pale. I went to the emergency room and Dr said anxiety. For six weeks, I had numbness, tingling, blurred vision, no appetite, but felt like eating raised my blood sugar and reduced the tingling. I had difficulty sleeping, nausea, anxiety, headache, stomach tenderness, abdominal cramping, bloating, poor concentration, clouded thinking, sweating,weakness in arms and legs. I was told to double the dose. I didn't. I had a gastric emptying study and was told not to take any medication. I felt amazing!! I was full of energy and my symptoms were reduced by second day. I told myself I should probably take it again and follow what my doctor ordered. So I took it that second night and woke up in the middle of the night with tingling, nausea, spinning room feeling, sweating, anxiety and abdominal pains. It has been a week since that episode. I will never take this poison again. F 33 6 weeks
40
7/1/2013
 1  Indigestion, Heartburn Headaches, mild nausea, light-headedness, dizziness, feeling "out of it", palpitations/rapid heartbeat, tightness in left/center chest, muscle soreness/pain in left neck/chest/arm/leg, loose stool, no appetite, terrible anxiety, hopelessness, struggle to handle even basic life tasks. Been taking name brand OTC for several weeks for lower abdominal soreness/burning/etc. Worked like a charm. Mentioned this to my doctor, and he told me to just go ahead and take it daily for as long as I wanted, no problem. About 2 weeks ago I started having pain in my left chest and arm combined with dizziness/lightheadedness, nausea, lack of appetite. Thought I might be having a heart issue and went to the ER. Enzyme/EKG etc. came back normal, so they sent me home. Less than 24 hours later, I was back in the ER after having tightness/pressure feelings in my chest, horrible anxiety, etc. Went to sleep, and woke up a couple hours later feeling like my heart was pounding and terribly anxious for no reason. Went through another round of tests, again all normal. In addition to the enzyme/EKG, this time they did a CT scan on my chest as well, nothing doing. The only thing that has changed in my routine is having started Prilosec daily around Mid-November. I've not been a perfect picture of health but generally feel pretty OK. Of particular concern to me was the anxiety/panic stuff, as I've never ever experienced that before. Stopped Prilosec almost exactly 72 hours ago. Still having most symptoms, but nausea and headaches have mostly subsided. If anyone has any experience they'd like to share with me as to their successful experiences dealing with these symptoms by stopping Prilosec, and how long it took to feel better, I'd love to hear them. Please email me! M 31 6 weeks
40mg 1X day
1/16/2013
Email
 1  Chronic gastritis Spiraling depression ending with panic attacks. Agitation and constant anxiety. Paranoia over food. Pain and weakness in limbs. Loss of appetite and thirst, leading to hospitalization for dehydration. Pain in neck and shoulders. Inability to get out of bed. This was the most horrible experience I've ever had with medication. I ended up in a terrible depression that included panic attacks. I was terrified I was going crazy, that my brain was broken. I was moaning and weeping and shaking, unable to control my body. I was very close to being medicated with Ativan when I came across this site about prilosec. I was shocked and appalled to see how many other people were having the same issues I was. I reported all this to my gastro, who told me it wasn't the medication. Why is no one doing anything about this? People are being driven crazy by this drug! It's been about 10 days since I stopped it cold turkey, and I'm finally BEGINNING to feel better. Agitation is still present, but depression is lifting and panic attacks have ceased. F 40 6 weeks
40 MG 2X day
1/5/2013
Email
 1  Barretts To all here......try a good probiotic. The prilosec kills all bacteria in the gut and this leads to many complications. From reading reports here, it seems they may have modified the formula recently. I am 2 years off the poison and feel almost myself again. M 57 6 weeks
40 1X day
6/29/2015
Email
 1  barretts all the bad side effects I HAVE BEEN TAKING A GOOD MAGNESIUM, CALCIUM, VIT.D SUPPLIMENT AND A GOOD PROBIOTIC. STATING TO FEEL MUCH BETTER. M 57 6 weeks
40 1X day
2/5/2015
Email
 1  gastritis Blurred vision,no appetite,dry mouth,severe headaches,palpitations,tingling in hands,depression,worst anxiety ever(never been anxious in my life)tired but could not sleep,feeling not quite 'with it''. Took this awful drug on and off,alternating with zantac for about 6 weeks,worst time of my life,thought I was going mad.Dr. would not accept the tablets caused these problems, silly me I believed him,trusted him and carried on taking them, after endoscopy then ultrasound found I had gallstones!!!What damage did these tablets cause as I did not have gastritis.Still suffering months later from side effects ,when will it get better? M 6 weeks
20mg. 1X day
11/15/2014
 1  barretts anxiety and depression 1 year later 1 year update....still have anxiety and depression. showed my doc. this site and he just poo pooed it. and he was a friend of mine before he was my doc. this drug and the f.d.a. suck. can"t go on much longer M 56 6 weeks
40mg 1X day
5/11/2014
Email
 1  acid reflux insomnia, depression, anxiety, weight loss (20 lbs. in 1 month) do NOT take this poison. i was a very strong, athletic guy who worked out 5 days a week for the last 20 years. in one month i lost all my muscle mass and have suffered many symptoms since i stopped taking the poison 11 weeks ago. i PRAY for recovery. doctors SUCK. M 55 6 weeks
20 mg 1X day
9/17/2013
Email
 1  reflux noted below in my first review I wrote a review last week and wanted to write again to give those of you who are experiencing the horrible side effects.. some hope...I chose another primary care doctor with the insurance I am with and saw her today. She said yes Prilosec is a strong drug and can cause these side effects especially if you have a sensitive system...she said it would take 4-6 weeks for the symptoms to resolve..that I am not crazy..and she did bloodwork for Vitamin B which is not absorbed when you are on this med. She also said she has seen this before. So to those of you who are having side effects hang in there... F 6 weeks
7/7/2009
 1  Acid reflux Shortness of breath, lump in my throat, dizziness & anxiety (due to not catching my breath). Went back to Dr. and he gave me an inhaler, I am quitting the Prilosec and see what happens. Worse right after taking it and throughout the day. Symptoms happened after a month, thought I was dying! Helped my acid reflux! F 41 6 weeks
11/28/2009

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