LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Endometriosis Insomnia, constant urination, hypersensitive back and neck muscles, headaches, mental fatigue, bloating Some days I could barely hold my head up. I was up every hour or two to urinate. That, on top of the hot flashes kept me up for practically two months straight. The drug is supposed to last for 30 days in your system. It took FIVE months for me to have a period. F 46 2 months
1 shot 1X M
11/22/2011
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 1  Endometriosis Terrible side effects. It took away my life for years. I took it 8 years ago and I still have side effects. For several years after the shots I had joint pain that made me move like someone who is 90, severe headaches, nausea, acne and unexplained boils all over my body. Since I have broken three bones and my favorite drink is ice cold milk, so I drink a lot of milk. Now I am slowly losing my teeth. For years I didn't leave the house because I was embarrased about how bad my skin was. I was afraid someone thought I had leprosy or something. Not to mention, I was so tired. All of these side affects have finally subsided, however, the absolutely worst was memory loss and inability to think logically. I use to be smart and I was an auditor. Now I cannot do anything that requires logic. It often happens that I drive places, then don't remember driving there. I might go out to eat with my family and the next day I do not remember any of it. DO NOT TAKE THIS MEDICINE FOR ENDOMETRIOSIS. THE SIDE EFFECTS ARE WORSE THAN THE DISEASE. ONE YEAR AFTER THE LUPRON I HAD A HYSTERECTOMY. DO NOT TAKE ANY MEDICINE BEFORE RESEARCHING IT FOR YOURSELF. DON'T TAKE FOR GRANTED THAT YOUR DOCTOR WILL KNOW EVERYTHING. F 46 3 months
8/20/2008
 1  Endometriosis Brain Fog-Sleeping problems-mood swings-acne-weight gain-Body stressed from the state body was put in. And nobody could understand I looked normal to them so What was I making a big deal over? They had no clue. Brain for pain I should of chosen brain. Months later I tool a class I had to drop out of because I could not retain what I was learning This stuff is toxic !!! I did lose my job over it because my brain fog and new personality was not helping. I wasn't evil to my co workers because I knew what I was feeling wasn't me. It is very tiring to be angry and not act on it. It was very tiring to be angry and act on it. I got a lump on my face under the skin like a second nose so I had it removed an now it is replaced with a scar. My body was so stressed from the unnatural state I was having left arm pain and ended up in the hospital checking on my heart for 2 days. The first month after the injection no major problems Then no brain(short term memory)I told the DR. I needed something for the body stress to calm down. She said go to a shrink. I had no choice. I had to try it if it would help. It didn't the visits to the shrink made me think like this..My body has a sick organ inside and it needs to be removed. Anyway I had to get a complete Hysterectomy and no one has the fix on HRT ask any Pharmisist And they will tell you wh F 46 1 times
7/24/2008
 1  endometriosis Hair loss, memory loss, severe hot flashes I will say that after I was off Lupron, I got preganant 5 months later. However, I would NOT recommend Lupron. This drug put me into early menopause the second I got off it. My docs have said that my body is actually 15yrs older than my age. I have very little short term memory, my hot flashes have never gone away and my last shot was 18 yrs ago. Now my daughter has started having hot flashes at the age of 14 and strongly believe it was because of the Lupron still in my system. I had endometriosis so bad that the doctors filmed my surgery and took it around the world for training classes. Ladies, get the hystorectomy!!! Yes, you'll feel better, still lose your hair and so on. If you have endo, don't keep the ovaries because the endo will still live. All the pain is gone except for the side effects of the Lupron. Several years ago there was a class action law suit againt the use of Lupron. You had to sign up for compensation however all the news regarding this just stopped being posted. I gave up and figured I got my daughter and will just deal with the worst of it the way I always have. If you can survive ENDOMETRIOSIS, you can survive anything! Can I hear an Amen?? F 46 6 months
10/1/2009
 5  Fibroids Hot flashes, especially intense at night. I, too, heard/read horror stories about Lupron but this was my last attempt at dealing with painful fibroids. I have a great MD who had great expereinces with Lupron, but still encouraged me to do research about the medication. I knew weight gain was a side effect, so I continued my running and was very careful with what I ate. I have to say I am very pleased with Lupron. The hot flashes are miserable, especially at night, but it beats the pain I was in prior to the protocal. I haven't had any issues with mood swings or loss of bone density, but I've always had dairy everyday and I take a calcium supplement as well. I can't say enough good things about Lupron. F 45 6 months
3.75 1X M
3/2/2012
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 5  Fibroids Hot Flashes mostly at night and slight headache at the beginning of my treatment. Not as bad as the comments on this site. Shrunk my fibriod from 26 week size down to 20 week size in 5 month pre-op. Everything went smoothly. F 45 4 months
4X M
7/15/2012
 5  fibroids very hot all the time-had to keep the A/C way down and then I was fine I had the 3 month injection for fibroids and non-stop bleeding. I absolutely loved this medication! I felt great! The bleeding stopped, my moodiness and irritability went away completely, my family couldn't believe how much fun I was, and I had no sexual problems. The fibroid did shrink slightly, but more importantly, the uterus' inflammation went away completely and the overall size was decreased. Clearly this is what I needed and was sorry when the effects wore off. I am now facing hysterectomy, but just wish I could stay on this medication until menopause. F 45 90 days
8/9/2007
 4  Fibroids Hot flashes, insomnia, fatigue I was expecting a lot worse from reading the comments on this site. But it's not as bad as I thought it would be. I do have hot flashes, and insomnia, and I am more tired than usual, but both my severe breast and abdominal pains have disappeared. Those who have said that this drug should be banned, etc., have no right to speak for others and I feel they are completely out of line to be so negative and possibly frighten others who may benefit from this drug. Everyone is different and everyone will react differently. I had the lupron injected to shrink my fibroids before hysterectomy. The person who commented that you can't have a hysterectomy in Canada unless it's cancer was either misinformed or lying. You most certainly can have a hysterectomy in Canada, even if you don't have cancer. For anyone checking this site for the first time, please don't get too stressed out because of some of the extreme and negative comments you read. I did, and I almost decided against it, which wouldn't h F 45 31 days
9/24/2007
 4  Fibroids, heavy cycles Hot Flashes, sleeplessness It has been GREAT. I am actually worried about getting off it. It was to shrink the fibroids , so far it actually hasn't done this, but I am not bleeding and feel like I have my life back. I am going for my 7th shot, and another sono to see if there has been an shrinkage onthe fibroid, so that I can be a candidate for Endometrial Ablation, a permanent solution to the bleeding without drugs, and outpatient(can't do it with a fibroid this size). Trying to avoid a Hysterectomy. Side effects have been minimal. I am glad I did not see these postings first. It may have stopped me from getting the shot. F 45 7 months
7/4/2007
 4  Fibroid reduction Significant hair loss and breakage I really have no complaints about Lupron (Eligard), for me it has significantly reduced the size of my fibroids so that my surgeon can perform a laproscopic procedure rather than an abdominal incision. I've experienced no side effects other than some significant hair loss and breakage. No hotflashes, sweats or confusion. It actually has not stopped my menses either.All in all, I'm glad I did it. I expected it to be so much worse. F 45 3 months
1X M
1/12/2013
 4  fibroids Dizziness, hot flashes,moodiness, insomnia, .my fibroid pain went away with days if my shot. Not sure if the lupron caused it, but I had one shot to last 3 months. After it wore off in the 4th month I started having bad heartburn that I am still dealing with and none of the pills the doctor is giving me are helping. Going to see specialist. F 45 3 months
10/9/2014
 3  Fibroid Tumors Hot flashes, mild headaches, dry skin, small rash on arm I admit I was terrified of getting the three month shot after reading the side effects that others were having. I am entering my third month and so far so good. I do experience the hot flashes but they are nothing like I was expecting. Just a warm flush and it's over. There was some pain at the shot site but that eventually went away. I have experienced headaches but nothing life altering. I am a marathon runner so I can't tell if my aches and joint pain are from the medication or the running. Either way it's bearable. I normally don't write reviews but I felt it was important to give a moderate view to someone who may be researching this drug. One word of advice would be to inform family and friends that you are taking this medication so that they are aware of any strange mood swings. I even told my boss. So far I haven't had any but I have had a few funny moments of memory loss. Again not life altering but I am more dependent than ever on my smart phone. F 45 3 months
not sure 1X M
6/10/2015
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 3  fibroid/pcos First month suffered 12 days straight of migraines. After that no migraines until 4 months on this dose, then they returned to once a month. Painful wrists and carpal tunnel like symptoms. Has brought tremendous relief in abdominal pain, painful periods and has reduced migraines, though somewhat. Has eliminated my acne, severe oily skin and reduced the number of skin tags. The tiredness though still remains and my weight gain has finally stopped, but not reduced. I have now been increased in my dosage as my hormone levels are still too high. It's a wait and see for symptoms vs hormone stability. F 45 12 months
7.5 1X M
9/1/2012
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 3  Fibroids Hot flashes, joint pain, stiffness, abdominal bloating & pain I was given two shots before surgery (hysterectomy) and I am not certain if I would do it again. I had my surgery before the Lupron could be effective so I never had the opportunity to see if the shots would truly be effective and help control the bleeding. Waiting to see if joint pain & stiffness subsides. F 45 1 months
2X O
8/12/2011
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 2  to shrink fibroids I have taken Lupron for 4 uterine fibroids. But two of them have grown and the other two only decreased minimally. The effect after the first shot, was very heavy menses for 2 weeks plus with many tissues along with extreme tiredness. For the remaining treatment, i had continued fatigue, hot flashes throughout the day, depression and had to limit my walking. I know everyone has different reactions but i hope this information may help someone else. F 45 3 months
1X M
3/16/2012
 2  endomitriosis/fibroids complete lack of control of my body 4 days after 1st shot. no focus,unable to sleep, pain everywhere,moody,hot flashes, night sweats,paranoid,achy, tired, initially no desirre for sex, came back, no problem. the strongest of the side effects lasted for two weeks, had mild bleeding for 2 weeks, 2 weeks after the first shot. Had a myomectomy in july 2008/ fibroids came back along with endo/ had three good weeks out of the 12. scheduled for a hysterectomy on March 11. Supposed to take another shot/ will not. Can anyone tell me how long after you quit the shot did you start bleeding again??? F 45 60 days
2/5/2009
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 2  Breast cancer treatment Migraines, hair loss, raging emotions, foot pain, hip pain, exhaustion, depression, 20 pound weight gain, blood pressure increased by 20 points. F 45 2 years
5/24/2020
 2  ER/PR positive breast cancer. Hot flashes, night sweats, painful joints, weight gain I couldn't take Tamoxiphen after I completed my chemo and radiation. My only option were the Lupron shots every 3 months for 5 years. I am now a year off the shots and I still have lingering issues from the shots. Still have the hot flashes, night sweats, mood swings, and my joints are a wreck. I've gained about 35 lbs in the past 5 years and am having a great deal of trouble taking any weight off. I wish there had been another option for me. F 45 5 years
3/3/2009
 1  Uterine Fibroids I started having hot flashes at the age of 32. Hot flashes, rapid weight gain, vision changes, acne, muscle and joint pain, extreme aggitation, heart palpitations, thoughts of causing others harm, short term memory loss, diagnosed with high blood pressure and arthritis, dizziness, shortness of breath, chest pains, looks like I am 5 months pregnant, and a daily migranes are all that come to mind at the moment. BUT I am sure the only reason I can't name more is because of the memory loss. Poison to body and soul. The temporary relief is NOT worth the long term suffering caused by Lupron!! I suppose the only thing that may make this nightmare worth it is if you are trying to conceive or you are being treated for a terminal illness. I am praying for all of us and even those that have read all of these posted warning and unwisely allows your doctor to convince you to alter your life forever. I only had fibroids and now I feel like an 80 year old woman. My daughter wants to know why I don't play with her anymore. Every day I have to tell them to be quiet because mommy doesn't feel good today maybe tomorrow. The Devil is a lie, I am going to play with my girls again. In the name of Jesus!!!!!!!!!!! F 45 3 months
10/12/2009
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 1  Endometriosis Severe anger, mood changes, joint pain, hip and leg pain, headache, hot flushes, weakness, fatigue, severe depression! Don't do it, 45 1 months
11.25 1X day
10/2/2021
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