LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  endometriosis hot flashes, back pain, mood swings, joint pain It is not helping me. I have taken 4 months worth of it and I am in more pain than I ever was. My doctor has no explanation. I think it might be the hormones I am on on top of the Lupron. I have had 2 laparoscopies and have actually been diagnosed with endo. F 29 4 months
1/26/2009
 2  Endometriosis severe depression, extreme fatigue, cramping, heavy bleeding So the first month has not been so great. I am extremely tired, but can't sleep. My period just showed up one day with such extreme cramping and pain that I could not even stand up..granted, not much different than before. Which is why I will continue to take the injections. I have had a laporoscopy already. Having 4 children, I would like to just have a hysterectomy, but the docs refuse to do it. My biggest thing is this...I HATE my husband. And I love my husband, so I really don't want to hate him. I just can't help it. Lupron is obviously causing some pretty severe mood swings. Hopefully I can get it under control before it causes a divorce! Email me if you are having problems too and care to talk about it :( F 29 1 months
8/24/2009
 1  Endometriosis Worsening of anxiety,mood swings, hot flashes that will turn into cold sweats(nausea tied into it)awful bone joint and nerve pain,tingly numbness,insomnia,lack of day time energy. I never comment on these things but i had to. Just to stress that no one should ever even entertain the thought of this drug let alone take it. December was suppose to be my very last injection(6th month)and i refused. It’s so infuriating to me that i was never informed on how much of a risk i was truly taking by agreeing to under go this monthly treatment. Not only did it NOT take my pain away..the pain that was the whole reason i was even put on lupron to take care of in the first place... but my pain and mental anguish is so much worse then when i started out. I’m a little over a month into completion and i haven’t slept in TWO DAYS! I am not exaggerating.. not so much as a cat nap in days. And that’s with me taking several OTC sleep meds! I have never been awake this long in my life. That..and the severe anxiety,nerve,bone,and joint pain and shortness of breath is torture. The many other side effects i can handle..these for me are by far the worst😔I was wondering if anyone could please tell me what to expect in the months after lupron? I haven’t been able to find anyone’s experiences each month after treatment.. I’m just hoping it gets better then this cause I’m really having a hard time seeing a light at the end of this tunnel. F 29 5 months
3.75mg
12/31/2019
Email
 1  endometriosis Fibromyalgia HELL! F 29 6 months
1x
2/10/2012
 1  Endo/PCOS/ Infertility F 29 1 months
1X M
7/19/2011
Email

Patient History
 1  Endometriosis Extreme hair loss, memory loss, fatigue, nausea, increase in original endo pain, depression, crying spells, hot and cold flashes, night sweats, increase in urination, loss of libido, occasional shortness of breath, awful taste in mouth So far, I'm miserable. I keep taking the shots hoping that if I wait long enough, it'll work and I'll feel better. No such luck. I spend alot of my time crying or thinking about how I'd be better off dead. I'm taking addback hormones, calcium, vitamins, Welbutrin, and handfuls of Ibuprofen to combat the lower back pain. I've also noticed shortness of breath which I assumed was from the humidity, but the more I think about it, I didn't really have that problem before my first shot. I'm giving it until the end of this month to see if it gets any better, but if I still feel this way, I'll stop the Lupron and discuss other options with my doctor. I won't say that this drug doesn't work, but it just doesn't seem to be working for me so far. F 29 2 months
7.5 1X M
7/12/2011
Email
 1  Endometriosis Hot flashes, night sweats, thinning hair, facial hair growth, deepening of voice, heart palpitations, bone pain. Lupron completely got rid of my pain for the six months I was on it. But when it wore off, a month later it was back. It was presented to me as an alternative to surgery, with the warning "Don't look this drug up on the internet or you'll freak yourself out". I really don't understand how this drug got approved. It has some unacceptable side effects for too many people. I know now that I should've just opted for the surgery. All Lupron did was postpone it. F 29 6 months
IV 1X O
1/30/2013
 1  Endometriosis I took two rounds of the 6 dose formulated for endometriosis first as a teen & 2nd in my early twenties. I now suffer from IBS, had to have my gallbladder out, blurred vision, fatigue, Chronic Migraines that don't respond to medication, Raynauds Syndrome, Tremors, Muscle Spasms & Jerks, Epilepsy, Odd weight fluctuations, Anxiety, Sleep Problems, Sleep Apnea, epilepsy, and I thought I had MS until I looked up a link to all of my current disorders & LUPRON POPPED UP! DO NOT TAKE THIS DRUG. Try continuous birth control skipping the sugar pill or anything before LUPRON. I took LUPRON to try to have children in the future, but what future do I have living this depressing life? My mom is staying with me & I am on disability. My short term has run out & I am not sure if I can even hold a job with all of this pain and fatigue. DON'T DO IT. F 29 1 days
3.7mg
2/21/2013
Email
 5  endometriosis the only side effect that I have had from the Lupron shot is hot flashes, night sweats, and some vagnial smelling. I was really scared about take Lupron from seeing the side effects that people have had especially on this site. I started my add back medication right away and at first I was a little crabby, and had spotting all the time I talked to my doctor though and she uped my add back meds and I was fine. F 28 6 months
1X M
2/16/2010
 5  IVF procedure Mild headaches in the PM. Noticeable skin thickening making it harder to get shots. That's really it. Super blessed and feeling great! I work, I work out, I take night classes, I do acupuncture once a week, and I am generally happy! F 28 3 weeks
10u
9/15/2015
 5  Stage III Endometriosis I had some hot flashing and night sweats, but it was sooo worth it! I was so scared to go on Lupron b/c of all of the horror stories I hear, but it was awesome. I am also very sensitive to hormones and can barely tolerate the moodiness from birth control. Lupron was actually better from me than birth control. I experienced less moodiness. I can't say enough good about this drug. Don't let people scare you. Everyone is different, but as a rule in general, people that are getting along with a medication aren't going to take the time to review it on the website. Go for it! F 28 6 months
5/14/2009
 5  endometriosis hot flashes, mild depression, mood swings, dry mouth and thristy. I was diagnosed with endomitriosis years ago. Completely frightened by the throught of Lupron I did nothing for a few years. About 5 months ago my pain from endo was too much to bare. I talked to my Doctor extensively about Lupron and decided to give it a shot. We had decided to do a 3 month trial, one month at a time to monitor side effects. I recently had my fourth injection (over a 4 month period). To me the side effects are worth being pain free. It has helped to have an understanding, support system and Doctor who took as much time as I needed answering my questions. My doctor told me that the younger you are the less side effects you tend to feel (relates to how much estrogen your body is producing). F 28 4 months
9/17/2008
Email
 4  Endo hot flashes, dry skin, excessive thirst, acne, joint pain(knees) I have completed my 6 month trial and have been mostly pain free. I was terrified after reading this site and some of the complaints from other users. Mostly I have had hot flashes in the nights, and I fix that with cold AC and a fan at night. I have been having problems with acne and excessive dry skin. For the most part I am very happy that I went ahead and used the medication despite the warning from this site. F 28 6 months
8/30/2008
 4  endometriosis (severe) with crohn's Extreme heat flashes, constant one after another, dizziness, nausea, horrible muscle cramping and muscle spasms in back and legs, insomnia, depression, crying spells, anxiety, bone and joint pain, urinary pain, itchiness, fatigue, "flu-like" feeling, some migranes, intolerance to heat and cold, vision changes, memory loss especially the first 3-5 days s/p injection. I would get faint, extremely nauseated right after injection, I would have to sit in the OB/GYN's office for an extra 30 min. to an hour to ensure I wouldn't pass out while driving home. Has anyone experienced this? F 28 3 months
3/4/2009
 4  Endometriosis Hot/cold flashes, face swelling, acne and face blemishes, lower and upper back pain, pain in the shoulders and neck, nausea, irritability, headaches and now migraines, memory loss and short term memory, and mood swings w/in the 1st mo I had really bad hot flashes, I tried to manage my body temp by wearing tube socks and short sleeve shirts. (sounds funny, but it worked for me esp. thru the winter season. I would have my fan on at my desk which also prevented me from sweating up a storm.) I had cramping the 1st 2 mos which have now subsided (thank god! b/c before then life was miserable. I couldn't do anything w/o being in pain which included walking,sitting, standing, etc. I got so stressed out I was depressed) Glad to hear I wasn't the only one out there dealing w/the same condition. I had my period the 2nd mo and during the 3rd mo I noticed my face swelled up and now I have acne. I got really bad lower back pain and then it moved up to my shoulders and neck. My headaches have gotten worse to the pt where I am getting migraines. Anyone else getting migraines? I have to take a separate med for my migraines so some of my side effects might be a result of this. The Dr. sd my headaches will only get wor F 28 6 months
3/9/2009
Email
 4  endometriosis during treatment: constipation, hot flashes, acne, sleeplessness Before Lupon, I had terrible nausia and cramping with my period. It was so painful I ended up in the ER twice. When I first got the shot, I was really sick and constipated an nauseated for about 2 weeks, during which time I was TERRIFIED at the thought of having this medication in my body for another 3 months. But it went away... and I felt FANTASTIC. I could go out with friends, go on vacation, make PLANS that did not hinge on the condition "...if I feel okay that day." My major side effects during that time were acne and sleeplessness. In fact, I did not sleep through the night for 6 months. THAT sucked, but was nothing in comparison to the relief I felt. Towards the end of the first 3 month shot, I started bleeding... and I bled for 5 weeks. I had to do estrogen add-back to get it to stop. The second 3 months shot was not as blissful, but I still felt a lot of relief. Again, when it started wearing off, I started bleeding, but that was only 8 days. It has now been a month since the shot wore off, and I still have some strange things going on. I am really tight in my abdomen and vagina. It is getting better, but it was painful at first. I had a headache for a few weeks that would not stop. That has gone away. Right now, I am having hot flashes. I think overall, my hormones are still just trying to adjust. We will see what happens! No matter what, I AM glad that I did it and had that 6 months of relief from my pain. Did anyone continue expe F 28 6 months
11/12/2009
Email
 4  Endometriosis I had extreme night sweats, hot flashes!! But nothing that I couldn't handle. At first I had joint [ain and heart palpitations. I took the Lupron and had an honestly great experience with it. I had the occasional night sweats and hot flashes. But it was nothing to complain about. I also got these itchy rashes anywhere I'd get hot or the sun was on me....at times that was irratating. Well I was going to continue the drug but first needed a dexa scan(measure your bone denstiy- side effect of Lupron is bone deplition) . I currently have osteoprosis and osteopenia at age 28. Some of that could of been from when I was a little girl and being diagnoised with juvenille rheumationd arthritis whos knows???? The drug made me feel better though! F 28 1 years
1X M
4/5/2011
 4  Endometriosis At the very beginning, I had some fairly extreme anxiety, had trouble concentrating and also had hot flashes. I began taking Lupron after I had major surgery in January for an endometrioma the size of a baby's head. It was attached to various organs in my body, but they couldn't just do a small surgery because they were uncertain what it was. I had NO pain and was extremely suprised when my gyno suggested that I get an ultrasound. I now have a "c-section" scar and no kids yet....but I was glad to hear it wasn't cancer. I was very reluctant to take the Lupron shot because of everything that I had read about teh side effects. I did start to get a little "crazy" teh first month and my doctor recommended that I try the shot along with Zoloft (an anti-anxiety drug). the combination of these two were unreal. It was the perfect balance. I was energized and actually lost 10 lbs, I didn't feel anxious, depressed, obsessive.....it was great. The only side effect that i had was hot flashes - but that wasn't a big deal to me. What I am more concerned with now is that i am off F 28 6 months
8/11/2006
 4  Endometriosis Headaches, Hot Flashes, night sweats, weight gain I took the last shot of my 6 month treatment (1 shot/mo) of Lupron in November. I read a LOT of horror stories online prior to taking the drug, but decided that personally, I needed to try it because the benefits could have out weighed the side effects. For me, that was a smart decision. I was in such severe pain. I was on continuous birth control, I had surgery, I took narcotic pain meds, I had cystoscopies and was on the IC diet for months. To say the least, I had investigated other options. I will not down-play the side effects. They are not pleasant. But compared to what I was living with, they are a walk in the park. If you are having mild discomfort and pain from endo, or other issues, think twice before taking this drug. The side effects will probably seem horrific if that is the case. But for me, I will take all those side effects and an extra 30 lbs over the pain and disruption endo was causing in my life. It may be short lived now that the shots are over, but I would do it again if needed and if it will mean keeping all of my organs necessary to conceive. The add-back therapy is a must to keep the worst of the side effects at bay. My doctor was thorough in explaining my choices, and I made an informed one. I suggest you do the same for your own situation. F 28 6 months
1X M
12/30/2011
Email
 4  Endometriosis Painful Periods a few night sweats, mood swings, no sex drive In the first month I still had the painful period and terrible mood swings. I was beginning to wonder if it was worth it. The second month got a lot better. I am going on my third month. I was told by my ob/gyn that if I could handle this drug and all of the side effects, they would give me a hysterectomy. I have not gained any weight and the mood swings have gotten a lot better. I still feel like I want to cry. I noticed that it is always when I am technically suppose to get my period F 28 2 months
5/22/2007

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