LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  ovarian remnesed diease hot flashes, nightsweats, headache, nausea,vomiting, depression, anxiety, moodswings, crying, hairloss, weightgain, no energy, no sex drive, insomnia desperate, i am not a candidate for surgury,so my oncologist thought that lupron would be the way to go , i took 6 shots 1 mthonth apart, the lupron did swrink the growth, so he thought that 6 more may really help , dont know!!!!!!! the side effects are just hell i am here to tell you , i hope after this round the side effects do gradually go away, its really scary right now, but if it shrinks maybe it will be worth it in the long run, F 43 8 months
2/11/2009
 3  endo, fibroids, cysts hot flashes, headache, backache mid level (small of back), night sweats, tingling right arm, indigestion-started day after 2nd shot, fatigue, mood swings-irritable and finally no intimacy. This is my last attempt at a solution before surgery. I have very painful intercourse (that manifested right after my marriage)along with heavy and painful cycles. I am not sure if this shot is working outside of the numerous side effects that I am experiencing. My husband says that he will gladly take a loving wife and no sex instead of who I am now------- I do not see it happening! I had my usual cycle on the 1st shot but it was not nearly as heavy or painful. I will only stay on this shot for 3 months due to the side effects. But, I am praying that this works so that I will not have to have surgery. Oh, itimitacy was not painful but..........libido. dang, need I say more? F 43 2 months
10/12/2006
 2  Multiple Myeloma Hot flashes, depression, dizziness, MEMORY LOSS, MOOD SWINGS. Complete loss of sex drive, and other things that I CAN'T REMEMBER. NO JOKE. I think I am the only man on this site. I took the drug as a study for MM a cancer of the blood. I was having what I consider severe problems and started researching. I found that this drug was used on male sex offenders and regarding sex drive caused near castration levels. I did have a complete remission from a terminal cancer. I do not know if it was helpful in the remission. M 43 6 days
5/24/2007
 2  Endometriosis Exhaustion, swollen breasts, migrains, hot flashes, slight memory loss, depression, anxiety, nausea Prior to taking Lupron I wasn't feeling great either. It seemed like I was feeling a little worse so I searched for Lupron side effects and found this site. It explains so much. I've had a full hysterectomy. I have severe endometriosis still and was hoping to stop any endo remaining with Lupron. I believe now most of my pain must be related to adhesions as my pelvic pain is not going away. I was really frigtened to take Lupron so I only took the 1 month shot. The side effects so far are very uncomfortable but I can still function and as I mentioned I wasn't feeling good prior to taking Lupron so I wasn't sure if how I feel now was Lupron related or prior pain related. I believe now that much of the side effects I have are Lupron related. I'm taking imitrex for migrains, tums for nausea, and pain pills for pain as well as prozac for depression. Although I don't think Lupron is helping and the side effects are not great, I can still function, a fear I had after my initial reading of side effects. So if you plan on trying Lupron, the side effects are real, but with a 1 month shot I can still work. I want to put this in the reviews because that was one of my biggest fears ... that I would be in bed 24/7. F 43 15 days
1X M
1/4/2011
 1  adenomyosis/fibroids headaches, hot flashes, no energy, depression,pain in ovaries, dark eyes, aches and pains etc. why????????????? F 43 4 days
4/11/2006
 1  to shrink fibroids Intense night sweats alternating with extreme cold spells. Terrible and abnormal depression leading to suicidal desires. Total inability to deal with normal ups and downs of life. The terrible truth about this drug was not available 12 yrs ago when I took it. It never helped my fibroids shrink. The depression was unbelievable, and looking back, I can't recognize myself as that person. I had to quit my management job in order to take several months to heal emotionally and physically. I would absolutely never recommend lupron. F 43 7 months
5/30/2007
 1  infertility Horrible drug. Reproductive endocrinologist prescribed as part of IVF treatment. 3 months AFTER completing 1 IVF cycle with LUPRON: still have not managed to lose the 10 pounds I gained on LUPRON, although have severely restricted calorie intake, (I have never had problems losing weight in the past before LUPRON) still have some tingling in my feet and aching in knees after crouching for a while ( I never experienced this before taking LUPRON ), Condition of my hair is scraggly and poor since LUPRON, Periods for past 3 months since taking LUPRON have been on abnormal 38-day-cycle (I am normally on a 30 day cycle), I had heart palpitations right after I discontinued LUPRON If you value your health and your sanity, DO NOT TAKE LUPRON Its effects may NEVER wear off, and if they do wear off, it takes MONTHS for it to wear off LUPRON IS NOT NOT NOT FDA-APPROVED FOR INFERTILITY!! F 43 11 days
3/22/2009
 1  Endometriosis Muscle aches, bone aches, migraines, peripheral neuropathy, bone loss, blurred vision, depression, anxiety I took lupron over 3 years ago and still suffer daily. I continue to have whole body aches and pains and there are days I feel like I am 95. I have a college degree, worked a full time job 12 hours a day prior to these injections, now I am on disability. This drug has ruined my life. F 43 9 months
1X M
5/4/2014
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 5  Fibroids I've only had the shot for 10 days and immediately experienced hot flashes and headaches. I had minor abdominal pain, but other than that, I feel fine. I'm more tired than normal and felt like I had flu symptoms the other day, but no complaints. I think this is going to work for me. I'm scheduled to have surgery in August so I can be done with all this discomfort. At first, I wasn't looking forward to it, but seeing that I have my children and grandchildren, I don't plan on traveling down the road of reproduction. I'm glad my OB suggested this and wish I knew about it earler. F 42 10 days
5/27/2008
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 5  Endometriosis Hot flashes. It was heaven sent within one month, years of pain subsided. I took two courses. The risk / benefits were well worth the sweating. No joint pain, hair growth (in fact, had more facial hair after I stopped injections). It helped delay a hysterctomy for two years. I now have to have one in the next few weeks. I wish a third course was possible. remember, the first month is Aweful. We can take control of our own mood swings, as long as we know its a problem. Family support and self education is a must. My Immuran is scarier than this. F 42 2 years
8/13/2007
 5  Endometriosis, fibroids, ovary cyst Surge in stronger migraines, hot flashes, achy, gums bleeding... I have had severely painful endometriosis since my teens, had one child at 37 yo, years after the laparoscopy to diagnose my endometriosis and ovarian cysts. I am 42, I had hot flashes anyway, severe abdominal swelling, all over body aches, and really clotted, brutally painful menses. In my second month of Lupron, I had initial stronger migraines, and hot flashes, but about 2 weeks later, all the side effects eased off, and I am pain free. I did not have a menses from the first shot on, my breasts are shrunk and pain free from the swollen painfulness they were before, my abdomen is no longer painfully swollen, I havent gained or lost weight, but the loss of pain is wonderful. I know it is different for everyone, but my prior pain was far worse then any of the side effects were. I would recommend if you want more children, or lessen the suffering of a hysterectomy, which is why my Dr recommended it. I tried pregesterone, which made me psychotic angry, I had crazy anger on my estrogen heavy natural self, and it has calmed down alot....I am impressed. F 42 2 months
50 MG 1X M
10/3/2012
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 4  26 yrs Endometriosis/Pelvic Pain Weight Gain , Acne, Night Sweats , Major Hot Flashes had to dbl the dose of meds for hot flashes . This is my 3rd go around on Lupron . I am 42 yrs old w/ no children. I have been on every type of hormone therapy you can think of .I have had at least 5or more surgeries because of this illness . One was so extreme I had the nerves removed from my uterus but I still have pain . At this point this disease has robbed me of quality of life . I am so afraid of the long term effects of this medicine that I don't know what to do. I am actually scheduled for have surgery sometime in Nov to find out why in the recent months am I starting to have major cramping all over again. I have been really thinking/praying for answer weather or not I should have my Dr. do a hysterectomy. I am so over this ..Mentally and Physically . This medicine was a temporary fix as usual. :-( F 42 6 months
30MG 1X M
9/25/2012
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 4   Severe endometriosis, ovarian cysts, serious menstrual pain I went on Lupron almost 6 years ago. I was desperate and the alternative for me was a complete hysterectomy. I had grave concerns about the side effects, but felt I had no choice. I was already infertile at 36 due to endometriosis and cysts. Here is my experience: The shots put me into drug induced menopause within about 3 weeks. I wish I had been more prepared for what that meant. I would have felt more in control if I had known what to expect. By the second shot, I was experiencing moments of intense depression. I could sit and cry for no reason. Never, had I dealt with this before. After the second shot (I'm experiencing full menopause/hot flashes etc by now) I started having serious joint pain. So bad, there were days I could hardly walk. I was only able to complete 5 of the 6 shots. I simply could not cope with the last one. After about a month, my period started and the joint pain and menopausal symptoms gradually declined. I was so upset when I still had pain during F 42 5 months
12/11/2007
 4  endometriosis None so far I can't say anything about helping with pain, because for the most part I never felt any pain. What my doctor thought was that I had 3 cysts with endometriosis. It would be a simple laproscopy to remove them and the endo, because I never had heavy bleeding or severe cramping. When he opened me up it was a horror show. Stage IV endo with everything stuck together. I ended up needing a laparotomy. He could not believe I functioned with normally. Because I have Epilepsy add-back is not an option. I'm praying I won't end up with horrible side effects, but after seeing the pictures of my insides I know I need to put my big girl pants on and deal with it. F 42 2 months
3.75 mg
5/23/2015
 3  Uterine Fibroids Mild headaches, some mild hot flashes during the night, sleeplessness, irritability and depression I had my initial injection on Jan 9th in preparation for a hysterectomy. I have been on a mild menstrual cycle for 19 days and will have my next injection on Feb 5th. I will await the final result. F 42 25 days
1/30/2009
 3  endometriosis weight gain, extreme hot flashes, itchy skin, moodiness This is my third time on lupron. The first time worked like a charm; it was heaven to be pain and period free. My period took a long time to come back with the same vengance. The second time it was ok; but the endo came back quickly. This time i have been on the drug for three months and want to take a break. It is wonderful not having the terrible and debilitating endo pain, but the hot flashes are excrutiating and the moodiness and weight gain very unpleasant! I know there is a trade-off here, but I do think that Lupron is better suited for younger women. I have also been diagnosed with Fibromyalgia; I have always wondered if the symptoms worsened - or were even caused by - the lupron. But, since hysterectomies also present problems, we all need to stay as informed as possible and make our choices that we feel comfortable with. I think at this point i am done with the lupron, but the first time really helped. Everyone is different! F 42 3 months
8/27/2006
 3  Fibroids/Heavy Bleeding I got one shot 7.15.2010 and had one long heavy period exactly 1 week later 7.22.2010. I have extremely severe hot flashes and all-day sweating-sweat literally drips off me. The shot was supposed to be given every 3 mosnths but I declined all additional shots. I have had no period since the week of 7.22.2010; the doctor has no idea when it might start again. As far as she is concerned "mission accomplished". As far as I'm concerned new doctor is in order as the fibroids and bleeding were 2/3 of the problem; pain during intercourse still occurs. F 42 6 months
11.25 1x3m 1X O
12/28/2010
Email
 2  Firbroid and heavy bleeding Extreme joint & muscle pain, hot flashes, nausea, big mood swings and fatigue. Did NOT shrink my fibroid which is the reason I was put on it...did eventually stop periods in the 3rd month. Still need surgery after all the side effects. 42 3 months
7/24/2009
 1  fibroids very heavy bleeding musle pain. hot flashes, continued heavy bleeding I got the injection and suffered side effects but my bleeding slowed down a lot for five or six weeks, then I got terrible stomach pain and cramps increased bleeding I went back to the doctor my hemogloban was 4.4 I was admitted to our small local hosp started on the first of four units of blood I would recieve and was transferred to a large hosp in a bigger city by ambulance and after I was stableized had a hysterctomy I was able to keep one ovary that happened on Friday and I am in a lot of pain but i am so glad that it is over, I do not think the shot helped at all and oh yea I am still havin hot flashes from it. F 42 2 months
every 3 mo 1X day
10/4/2010
Email
 1  to shrink fibroids for surgery within 48 hours I developed phlebitis and blood clots. I later suffered a Pulmonary Embolism. Other "usual" side effects included hot flashes and mood swings. Most recently my hair started to fall out. It did really shrink the fibroids, but it lasted only 3 months. Now I have to wait even longer to have the hysterectomy because of the Pulmonary Embolism. F 42 1 months
one shot 1X M
9/4/2010
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