LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  intestinal endometriosis at first: mood swings, occasional hot flashes, extreme fatigue now: Hot flashes every hour, zero sex drive, dryness, fatigue Despite all that, I am virtually asymptomatic for the endometriosis. I have had 2 "attacks" since I started and none of the usual bowel issues at all that I had regularly for 15 years. F 37 3 months
12/27/2009
 4  Part of IVF treatment Miagranes increased. SEVERE joint point pain, especially in my ankles. The worst acne since I was a teenager. Bloating. Increased crying. The only reason I took this medication is because it was part of my in-vitro fertilization protocol. It's been a rough 25 days & I just did my last injection tonight. F 37 25 days
12/13/2009
 3  Excessive Bleeding/Pain Hair loss, lots of it. migraines, decrease libido, vag. dryness, I havent had hot flashes yet, however, Ive only been taking this for one month. I still have grave concerns over what happens after the completion of this medication. And i really hope I still have hair left after this is all over with. Other than that I still think its working well. F 37 1 months
9/8/2009
 3  To treat endometriosis pain Depression, mood swings, SEVERE night sweats, hot flashes, blurred vision, fatigue. I have mixed feelings about this drug. I had such severe endometriosis pain and having a hysterectomy at 36 was not an option for me. I have had 2 surgeries to remove large cysts and scar tissue surrounding my left ovary. I have one more month to go before my 6 month Lupron treatment is over. I still experience pain in my left ovary - but 85% less since the Lupron. I hope the pain continues to subside once my body goes back to "normal". F 37 5 months
10/26/2008
Email
 3  uterine fibroids none thus far I have a question. How quickly does this drug take effect? I just got my first dose on Sept. 19th. I was supposed to start my next period Sept. 22nd. It can't work that fast, can it? I mean, there are other reasons why my period might be wonky, it often is, but this is weird. I've had more energy lately and my stomach looks like my stomach for the first time in I don't know how many years. The general fatigue, pain, and malaise that came from my fibroids seems to have evaporated. I don't trust anything that works this fast but I have to say that I feel better than I've felt in the past year. F 37 7 days
9/25/2008
 2  endometriosis WEIGHT GAIN, bloating, memory loss, TIRED, joint pains galore, emotional, cant sleep, sweats all night. Dizzy, Neaseaus- hot easily and faint. NOT NORMAL On 4th shot. 2nd time around- I did this 12 years ago. I dont remember ANY of this. I have gained soooo much weight! PLEASE someone tell me what happens after the shot it over? WIll I lose this weight? Its unreal- I dont even look like myself,m I work out and write down what I eat. Nothing any different Im doing but still I am gaining. HELP! I feel awful........i hope it helps like it did the 1st time but this is unreal....cant even find words to describe.... F 37 4 months
7/30/2006
 1  endometroius It has been the worst "roller coaster ride" of my life. I have bled bascially the whole time on the drug (except for a 2 week time span). High anxiety, not wanting to be around crowds or groups of people.I want to stay at home in my safe little "shell". This is NOT me! I am usually a very outgoing & bubbly type person. The feeling of hopelessness & suicidal thoughts are the worst. It has greatly affected my family. No sex drive....this drug should not be allowed. I was not told all of all the possible side effects. I can deal with hot flashes/ night sweats, but the emotional upheaval is absolutely the worst. I am so scared. I am not continuing on with the 4th injection. It is not worth it!!!!!!!!!!!!!!I want my life back!!! It needs to be taken off the market F 37 90 days
4/30/2007
Email
 1  Adenomyosis, Endometreosis Headaches, hot flashes, insomnia, constipation, mood swings, depression, burning skin, itchy skin, bloating, fatigue, memory issues - have to keep everything in a calendar now. I am supposed to get my 4th shot next week. I get it once a month. However, last Friday my period started again. At first it was a little light, but now at 7 days, it's heavier. I also am experiencing major cramps and bloating. I have a hysterectomy scheduled for July 13th. I'm totally unhappy on Lupron. I tell my doctor each month that I don't want it and he claims I need it. Now, I have all the side effects plus my period. I called the doctor and they said that if the bleeding doesn't stop they'll put me on estrogen. So - they've stopped my estrogen with a drug with lots of side effects and now have to give me back estrogen (with lots of side effects). Avoid this drug if possible. I feel like it's really thrown me for a loop. F 37 3 months
5/20/2005
 1  Endometriosis Severe anxiety attacks, mood swings. I was supposed to take 6 injections over 6 months. Thank goodness my symptoms appeared within the first two weeks because I cancelled my prescription. Although the pain went away for a couple of weeks, it came back with a vengeance! I was having severe anxiety attacks and mood swings. 2 months after getting off of the Lupron, I had a miscarriage and will be having my uterus and ovaries removed. I wish I'd had this done from the start... AVOID LURPON! F 37 1 months
1X M
5/19/2010
 1  Catemenial anaphalaxia Period didn't stop until two months after receiving Lupron. I have headaches, hair loss, palpations, difficult breathing, joint pain, extremely tired and depression. Not worth it. This was my first and last time on lupron. F 37 1 months
3 month
7/24/2012
 1  endometriosis Severe anxiety, severe depression, hair loss, hot flashes, night sweats, crying for no reason I was given a 3 month Lupron Depot shot. F 37 3 months
1X day
8/27/2012
Email
 1  Frozen Transfer Fertility cycle Weight gain of 10 lbs in 10 days, massive bloating, dizzyness, exhaustion, swelling of face, asthma symptoms, extreme mood swings, crying for no reason, depressiom Used at beginning of frozen cycle, not sure WHY when it's known to cause birth defects, you would think a drug like that would not be used right before an embryo transfer. I pray this works because I can't go through this again F 37 10 days
2/25/2009
 1  Endometriosis and fibroids Massive bone and joint pain, severe hot flashes, headaches, decreased sex drive, anxiety and severe irritability. The cons outweigh the pros for sure. F 37 1 years
30mg 1X day
1/5/2021
 5  Stage IV endo very mild hot flashes but those didn't start until the 2nd month. Slight decrease in sex drive. First month I was more tired than normal and had some headaches but both went away. I was so nervous about taking Lupron and I avoided it at all costs because of what I read of other people's experiences. What I've learned is that you have to rely on your doctor and don't assume you'll have a terrible time with it. Some people do but that doesn't necessarily mean you will. I am a professional classical singer and I was worried about what it would do to me vocally and I've been fine. I'm also a triathlete and I was terrified of weight gain and joint pain but neither one have been a problem. The pain from the endo is GONE and that's worth so much to me. I have it everywhere - on my colon, small intestines, in my left ovary, you name it. The pain was making my energy worse than the Lupron. I told my husband that if I could stay on it I would. After my 3rd shot next week, I'll have one to go. Do your research on the drug and find a doctor you trust. F 36 2 months
6/11/2009
Email
 5  Fibroids Breast tenderness. Have had no side effects so far from Lupron. F 36 10 days
3.75 1X M
4/14/2011
 5  Endo, Fibroids, Enlarged Uterus It honestly feels as if I'm not on anything at all, and I'm in my third month of treatment. I'm normally 'cold-blooded', so if I have had hot flashes, they have been minimal and barely noticeable. No weight gain or loss, no lowered sex-drive, no mood swings, headaches, NOTHING really to speak of. Only thing is I had a 5 week period two weeks after my first injection, but after about 11 or 12 days it was pretty light. Nothing at ALL like my normal, nasty periods (still needed a pad, though). Was having a lot of pain up till two weeks after my second injection. Lately I've been feeling GREAT! It reminds me of life before my estrogen levels were so high. I've had chronic pelvic pain since I was 11 years old (I'm almost 37 now), and I was even willing to deal with hair loss if it meant I could feel better (thank God, though, no real side effects at all for me!). I just thank God for some relief! For me, it's working with NO side effects. I know everyone's body is different, but for those suffering with severe pain as I was, I highly recommend it. F 36 2 months
11/5/2005
Email
 4  endometriosis menstrual cramping and pain with daily bleeding while on birth control pills. After having a laproscopy two years ago, symptoms began returning. I am taking this treatment to post-pone another laproscopy. I was fearful in taking Lupron as I have heard from my doctor and read about the side-effects. However, I have had good results thus far and hope they continue. Initially, I suffered from some migraines, leg pain, and pelvic pain, but after a few weeks these symptoms along with the bleeding have stopped. I have not experienced any hot flashes, night sweats or mood swings. In fact, I have had an unexpected and very pleasing result of depression and anxiety dropping out of my daily life. I have not felt this good since my early twenties. I hope the treatment continues to bless me with these good results. F 36 1 days
6/3/2006
 4  endometriosis menstrual cramping and pain with daily bleeding while on birth control pills. After having a laproscopy two years ago, symptoms began returning. I am taking this treatment to post-pone another laproscopy. I was fearful in taking Lupron as I have heard from my doctor and read about the side-effects. However, I have had good results thus far and hope they continue. Initially, I suffered from some migraines, leg pain, and pelvic pain, but after a few weeks these symptoms along with the bleeding have stopped. I have not experienced any hot flashes, night sweats or mood swings. In fact, I have had an unexpected and very pleasing result of depression and anxiety dropping out of my daily life. I have not felt this good since my early twenties. I hope the treatment continues to bless me with these good results. F 36 1 months
6/3/2006
 4  to shrink endometriosis mild hot flashes, itching, waking up in the middle of the night and having trouble falling asleep again. I had an endometrioma rupture on one ovary and it was removed. I am taking Lupron so I can keep my other ovary because it also has a cyst growing. So far, it is working! The cyst is shrinking! F 36 4 months
10/29/2008
 4  endo,after fibroid surgery The only side effects I have are night sweats, heat flashes and mood swings. I had surgery at the end of January, I have only had one injection. That was for the 1 month. My doctor didn't want me to get anymore injections; that is a great thing. My husband and I want to have children, so I hoping that lupron will help all the past problems withendo, and fibroids. F 36 3 months
5/2/2008

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