LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4   I had major hot flash and night sweats. Also couldnt stop eating and gained 20 pounds. The worst part was the weight gain because each month i put on like 5 pounds. However i stopped bleeding after the second shot and had little to no pain the rest of the time i was on the shot. We will see how it goes off the shot. F 22 6 months
2/26/2017
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 4  Endometriosis Soreness the first week. I wanted to submit a review after I finished taking Lupron because, when I first took the drug, the reviews terrified me. I was convinced I was going to end up depressed, gain 50 lbs, and be unable to walk. Well, I just finished taking it (two times of once every three months) and I had absolutely no problems. Of course, I was on Depo Provera for a long time before that, so my estrogen was already pretty low. Still, not everyone will have problems, so hopefully someone who just started the drug will see this and be given some perspective. In terms of pain, btw, it was okay--Depo helped with the pain more. F 22 6 months
1X O
2/16/2010
 4  Endometriosis I have had terrible hot flashes, and more recently my endo symptoms have come back. Well without boing you with TMI. I have had 4 laps (2005,2006, 2007,2008) Following my last one I was put on Lupron I have taken it continuously (except for 2 months) since then. I get bone density scans every 6 months. It has been a life saver. I am hoping when I have my next lap the docs will say I have the green light to have babies...Don't rule it out. Taking Lupron gave me an extra year of no surgery...The side effects are mild compared to the pain!! F 22 2.5 years
3.25mg 1X M
5/22/2010
 4  Post-op for endometriosis and cysts DON'T LET THESE POSTS SCARE YOU. It's been bad, but different for everyone. So, if you and your doctor think its best for your overall health, it is definitely worth the temporary misery. I'm going on my 4th shot. I have hot flashes/ night sweats allllll the time. In fact, I'm having one right now. I mean, it's the middle of winter and I have to wear a tank top or t-shirt under a hoodie, for those times when it gets unbearable. I feel a little less focused, more emotional and irritable. I had some vaginal dryness for about a month, but that has subsided for the most part. I find all of this easier to deal with if you constantly remind yourself that it's just the drugs taking over, its worth it, and you're not normally a total basketcase. Sometimes, that doesn't work! I'm not gonna lie, it sucks ass. But even though I really hate the side effects of lupron, I'd do it all over again if it meant I could be healthier and have children of my own someday. :) F 22 3 months
1/10/2008
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 3  Endometriosis I've been off of it for 2 years and I still have hot flashes and no sex drive!!! But It has reduced the rate at which the endo was growing. But if I had to do it all over again, I wouldn't. F 22 6 months
1 x month
2/10/2012
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 3  Endometriosis Mood swings, hot flashes, vaginal dryness,feeling achy all over, and Im still not the same and I have been off it for 3 months. I was on the shot for 6 months and the side effects were rough to deal with. I have started my period back and I am hurting the same way I was before. F 22 6 months
11/26/2009
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 3  ovarian cyst and endo hot flashes, depression, anxiety, night sweats and bad acne break outs i wasnt very excited to start on lupron because my mom suffered from endo and cysts so she warned me about all the crazy side effects. This is a very powerful lil shot! F 22 3 months
7/23/2009
 3  Endometriosis Long-term side effects after treatment had worn off. Lupron did what it was supposed to, I got all of the expected side effects which were bearable. But the week the Lupron should have been out of my body, I got severe symptoms that have lasted almost a year. The side effects while I was on Lupron were really not that bad because I had read up on it and knew what to expect. The add-back therapy with it helped tremendously! The only thing that affected my life significantly was short-term memory loss and now a whole list of symptoms that seem to have been caused by the treatment. If anyone has had long lasting anxiety, depression, palpitations, dizziness, fainting,etc. after finishing treatment PLEASE e-mail me. It has to be from this shot. F 22 7 months
5/7/2009
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 3  post op endometriosis acne, mood swings, joint pain, depression, hot flashes, headaches, fatigue, light headiness I've only had my first shot so far and ive already felt a lot of the side effects but theyre all pretty much bearabe. i only hope that they don't worsen or get extremely bad until i finish my 6 month treatment. I wouldnt reccomend this drug unless u REALLY need it and is a last option. F 22 1 months
6/21/2008
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 3  post op endometriosis Terrible acne, depression, fatigue, breast changes, nervousness,palpitations, mood changes, some hot flashes, daily headaches I'm on my 3rd shot and the symptoms seem to have lessen. The symptoms I'm currently experiencing are pretty bad acne, mild depression, extreme fatigue, some nausea, my breasts have shrunk an entire cup and I get palpitations and nervous out of nowhere. Hot flashes have lessened very much since my first shot. Daily headaches that only go away with sleep. It's not so bad people F 22 3 months
8/6/2008
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 2  Mild Endo diagnosed in July 07 Hot flashes, night sweats I have been receiving the Lupron injection of 3.75mg every for weeks since late Aug 2007. I was told by my doctor that this could take a few injections for it to work. I just had my 11th injection yesterday and in no way has this drug helped me so far. On top of all of that, my doctor added Interstial cystitis to my list of dyagnosis in Oct 2007, so it makes me even wonder if my real pain is from the Endo or the IC. My pain is pretty consistant and with my last three injections of Lupron, I have actually began to feel worse. I have been bleeding for the last two months and am not sure if there is any point to staying on the Lupron, but I do know that when I am late getting an injection (even by just a week) I am in unbearable pain, so again, its hard to pinpoint the pain. After reading over a lot of the comments on here, I am thankful that the Lupron has only caused mild sideeffects within me..I will tell you ladies that along with the Lupron my doctor prescribed Aygestin so comb F 22 11 months
8/21/2008
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 2  Severe Endometriosis Severe pain thru whole treatment(pain made 10x worse) lower back pain, numbing of left leg, headachs, hot flashes, mood swings, mild weight gain. Still deciding whether to finish 6 mo treatment plan?? F 22 2 months
12/8/2011
 1  endometreyosis EXTREMLEY BAD HOT FLASHES AND NIGHT SWEATS!VERY BAD NAUSEAU AND VOMITTING LIKE MORNING SICKNESS ALL THE TIME. VERY BAD HEADAHCES. EXTREME WEIGHT GAIN (25 TO 30 LBS IN 4 MONTHS) .TIREDNESS. YEAST INFECTIONS. UP AND DOWN EMOTIONS.CRYING OVER NOTHING AT ALL. EYE SIGNT CHANGE.JUST PURE MISSERY...... I DO NOT RECOMMEND IT TO ANYONE. THIS SHOT IS HORRIBLE. I STILL HURT AND EVERYTHING. THE ONLY GOOD THING IS THAT I DO NOT HAVE A PERIOD. F 22 4 months
7/21/2006
 1  ENDOMETRIOSIS Mild hot flashes, severe mood swings, joint pain, back pain, anxiety, night sweats, abdominal distention, weight gain, nightmares. I took lupron for 6 months for enometriosis that was more prominent on my left side than my right. I gained 25lbs on the shot the majority of it stomacch weight, and am having a really hard time getting the lbs off. Shot not worth it, still in pretty bad pain...add back therapy helped a little. I still have problems, cysts. I have been off for a month and a half and am still waiting for my period. I would rather live with the endo on pain killers - not much alternative. F 22 6 months
5/22/2008
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 5  Endomitriosis No side effects. I felt great the entire time. I felt great when I was on Lupron. I didn't have to worry about pain, cycles, or blood. I would suggest the add back therapy to help even out the hormones. F 21 12 months
6/19/2009
 5  endometriosis and severe bleeding The month after the first injection was bad, and I had a lot of weakness, mainly because it lengthened my period. But after the second shot, the side effects were very minimal, limited mainly to hot flashes, which are now almost non-existent. I read the comments on this page the night before my first injection, and I cried. I almost didn't go through with it, but I am SO GLAD that I did. Lupron has been an absolute God-send. Most of the horrible side effects listed on this page are what I got when I took birth control, so I was terrified to try something else. But it has helped me SO much, and I have regained my life. I recently went from the 1 month shot to the 3 month, and my problems without Lupron are so severe, that I am taking it for ten months instead of the normal six. I'm so thankful to have it. F 21 6 months
8/22/2009
 4  Endometriosis HOT flashes!! nightsweats, weight gain due to uncontrollable urges to eat, headaches, joint aches, mood swings, and breast tenderness and enlargement. I'm 4 days into my second shot and have put on 5 pounds in the last month. I have been relieved of all pain that I was experiencing so it's a catch 22 situation. By the 2nd week of my injection, one breast was noticably larger than the other making it hard to fit into my bras. The other has started to catch up, but now I must invest in new bras. I find it hard to stop eating and don't quite get the "I'm full" feeling until my stomach is fully extended and stuffed though I still feel the urge to eat. I love the shot, yet I hate it all the same. Hot flashes and nightsweats come and go as they please, but are highly annoying. I experience joint pain mainly in my hand. Mood swings are major and I sometimes cry for no reason. As a school teacher, I didn't know if my kids were getting were acting horribly or if I was to blame. It is a weird feeling. F 21 2 months
5/2/2006
 4  Endometriosis Hot flashes, mood swings, anxiety, weight fluxuation and night sweats. I was in a lot of pain with my endo, and I was desperate to find anything that would make my daily life more comfortable, especially during my periods. They were lasting for a month or two at a time and were excruciting enough to put me in the hospital. The shots made me feel pretty crappy at night, and I got very frequent hot flashes. However, I am pain free now that my 3 months is up. The worst side eefect for me came after my shots stopped. I have been off for three months, and I am now on anxiety medication. My doctor said it could be from the shot, or a combination of that and my job, which involves working with victims of crime. Overall, it was probably worth it. Haven't had a period for 45 days now. Don't know if it is the shot, or if our efforts to get pregnant are finally working. Overall, the benefits outweighted the risks... F 21 3 months
1/12/2009
 4  endometriosis headaches, pain at the injection site, hot flashes, mood swings, increased appetite, increased sweating, short term memory problems after injections i tend to have pain at the injection site for about a week. it just feels like a bruise. I also tend to have headaches for the first couple weeks after an injection, but they're not too bad. For about a month after an injection i ahve problems retaining short term memory and this tends to make it difficult to focus. I've gained a lot of weight and have the typical menopause symptoms, but it has definitely helped my pain associated with endometriosis. Ive especially noticed a difference in regards to pain during intercourse. F 21 4 months
1/29/2009
 4  Endometriosis, Constant Cramping Hot flashes, night sweats, forgetfullness, mood swings, anger, depression, acne. I am currently on Lupron after having my Laparoscopy in the end of June. The lap did not help as much as they thought it would, I was still bed-ridden with pain. The Lupron has helped to ease the majority of the pain, my biggest qualms with it are the mood swings and forgetfulness. My worst mood swings were generally right after my shot. I notice that I tend to get angry far quicker than before and my patience is short, but now that I am aware of it I try to keep it in check. The depression is difficult to deal with because my fiance is deploying next month. Though the side effects are unpleasant I have not been in tremendous pain like I was before. I did extensive research before taking Lupron and I reccomend that everyone do that (with any medication). The reason I started the lupron is because I want to have kids and did not opt for the hysterectomy. F 21 3 months
1X M
10/23/2011
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